Magnetic-silver nanostructures were synthesized via optimized chemical conditions, and their characteristics and cytotoxicity were compared as candidates for the magnetic delivery of silver nanoparticles toward cancer...Magnetic-silver nanostructures were synthesized via optimized chemical conditions, and their characteristics and cytotoxicity were compared as candidates for the magnetic delivery of silver nanoparticles toward cancer cells. Magnetic-silver nanostructures were prepared through the reduction of silver ions in the presence of iron oxide nanoparticles using three different reducing agents （glucose, maltose and sodium citrate）. Their physicochemical characteristics were determined using ultraviolet-visible spectroscopy, X-ray diffraction analysis, transmission electron microscopy, selected area electron diffraction analysis, Fourier transformed infrared spectroscopy, atomic absorption spectroscopy, vibrating sample magnetometry and differential scanning calorimetry. Cytotoxic activities were evaluated against a human liver hepatocellular carcinoma cell line. Fabricated nanostructures, which exhibit differences in size, silver content, magnetic saturation value and cytotoxicity, represent sufficient superparamagnetic properties and considerable cytotoxicity to be suggested as effective tools in magnetic targeting of silver nanoparticles as an approach to cancer therapy.展开更多
The shape-controlled silver nanostructures have been widely used for template synthesis of metal nanostructures with desired morphologies and compositions for specific applications by galvanic replacement reaction,whi...The shape-controlled silver nanostructures have been widely used for template synthesis of metal nanostructures with desired morphologies and compositions for specific applications by galvanic replacement reaction,while the silver is sacrificed as oxidized to silver ion and abandoned as by-products.In view of the broad application prospect of the obtained metal nanostructures,the cost and environment problems after the template reactions should be taken into account for the large scale production in the future.To solve this problem,we conceptually demonstrate that the wasted AgCl generated from the template reactions can be easily recycled for the synthesis of valuable Ag nanowires.As representative examples,the average recovery of silver can be about 69.8%-84.6% after the template synthesis of Au/Pt nanostructures.The resynthesized Ag nanowires show uniform size distribution and excellent physical and chemical properties for the fabrication of transparent electrode and template synthesis.展开更多
The flower-like silver nanoparticles have been synthesized by reducing silver nitrate （AgNO3） with ascorbic acid （AA） as the reductant and polyvinyl pyrrolidone （PVP） as the capping agent under vigorous stirring...The flower-like silver nanoparticles have been synthesized by reducing silver nitrate （AgNO3） with ascorbic acid （AA） as the reductant and polyvinyl pyrrolidone （PVP） as the capping agent under vigorous stirring. Such flower-like nanoparticles are aggregates of small nanoplates and nanorods. They were tested as substrates for the surface-enhanced Raman scattering （SERS）, showing high sensitivity for detecting Rhodamine 6G （RBG） at a concentration as low as 10 7 mol/L. It has been found that replacing mechanical stirring with ultrasound sonication would drastically change the particle morphology, from flower-like nanoparticles to well-dispersed smaller nanoparticles. Furthermore, when trace amounts of NaC1 were added into the reagents, well-dispersed Ag nanoparticles formed even in vigorous stirring. These phenomena can be explained with the diffusion and reactant supply during nucleation and growth of Ag nanoparticles.展开更多
基金financially supported by Shiraz University of Medical Sciences,Shiraz,Iran(Grant Number92-6587)
文摘Magnetic-silver nanostructures were synthesized via optimized chemical conditions, and their characteristics and cytotoxicity were compared as candidates for the magnetic delivery of silver nanoparticles toward cancer cells. Magnetic-silver nanostructures were prepared through the reduction of silver ions in the presence of iron oxide nanoparticles using three different reducing agents （glucose, maltose and sodium citrate）. Their physicochemical characteristics were determined using ultraviolet-visible spectroscopy, X-ray diffraction analysis, transmission electron microscopy, selected area electron diffraction analysis, Fourier transformed infrared spectroscopy, atomic absorption spectroscopy, vibrating sample magnetometry and differential scanning calorimetry. Cytotoxic activities were evaluated against a human liver hepatocellular carcinoma cell line. Fabricated nanostructures, which exhibit differences in size, silver content, magnetic saturation value and cytotoxicity, represent sufficient superparamagnetic properties and considerable cytotoxicity to be suggested as effective tools in magnetic targeting of silver nanoparticles as an approach to cancer therapy.
基金supported by the National Natural Science Foundation of China(21431006)the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(21521001)+2 种基金the National Basic Research Program of China(2014CB931800 and 2013CB931800)the Users with Excellence and Scientific Research Grant of Hefei Science Center of Chinese Academy of Sciences(CAS)(2015HSC-UE007 and 2015SRG-HSC038)the CAS(KJZD-EW-M01-1)
文摘The shape-controlled silver nanostructures have been widely used for template synthesis of metal nanostructures with desired morphologies and compositions for specific applications by galvanic replacement reaction,while the silver is sacrificed as oxidized to silver ion and abandoned as by-products.In view of the broad application prospect of the obtained metal nanostructures,the cost and environment problems after the template reactions should be taken into account for the large scale production in the future.To solve this problem,we conceptually demonstrate that the wasted AgCl generated from the template reactions can be easily recycled for the synthesis of valuable Ag nanowires.As representative examples,the average recovery of silver can be about 69.8%-84.6% after the template synthesis of Au/Pt nanostructures.The resynthesized Ag nanowires show uniform size distribution and excellent physical and chemical properties for the fabrication of transparent electrode and template synthesis.
基金financial support for this work from the Natural Science Foundation for Young Scientists of Shanxi Province of China (No. 2015021078)International Cooperation of Science and Technology Project in Shanxi Province of China (No. 2014081006-2)
文摘The flower-like silver nanoparticles have been synthesized by reducing silver nitrate （AgNO3） with ascorbic acid （AA） as the reductant and polyvinyl pyrrolidone （PVP） as the capping agent under vigorous stirring. Such flower-like nanoparticles are aggregates of small nanoplates and nanorods. They were tested as substrates for the surface-enhanced Raman scattering （SERS）, showing high sensitivity for detecting Rhodamine 6G （RBG） at a concentration as low as 10 7 mol/L. It has been found that replacing mechanical stirring with ultrasound sonication would drastically change the particle morphology, from flower-like nanoparticles to well-dispersed smaller nanoparticles. Furthermore, when trace amounts of NaC1 were added into the reagents, well-dispersed Ag nanoparticles formed even in vigorous stirring. These phenomena can be explained with the diffusion and reactant supply during nucleation and growth of Ag nanoparticles.
