A medical device is an instrument that includes components,parts,or accessories to diagnose or treat patients.Since the complexity of medical devices has increased in recent years,functional safety and basic safety ar...A medical device is an instrument that includes components,parts,or accessories to diagnose or treat patients.Since the complexity of medical devices has increased in recent years,functional safety and basic safety are required to ensure the overall device safety.Functional safety is part of the overall safety that relates to the equipment under control(EUC)and to the EUC control system that depends on the correct functionality of the electrical/electronic/programmable electronic(E/E/PE)safety-related systems.This study proposes approach methods to functional safety of medical devices for which it is important to correctly identify the safety functions and the safety integrity level(SIL).The relationship between the functional safety and essential performance is identified focusing on the safety function.The essential performance of E/E/PE systems is defined as the safety function of the functional safety.The target SIL of the essential performance is determined according to the potential risk levels,based on the classification rules of medical devices.This approach is applied to the pulse oximeter as a case study.The target SIL for the functionality of the power-failure alarm condition is determined to be SIL1.The target SILs of other functions are determined as SIL2.展开更多
According to the study made by United Nation Economic Commission for Africa, Ethiopia stands as one of the worst countries with respect to road safety performance in terms of traffic accident fatalities per 10,000 veh...According to the study made by United Nation Economic Commission for Africa, Ethiopia stands as one of the worst countries with respect to road safety performance in terms of traffic accident fatalities per 10,000 vehicles (i.e. 95 in 2007/8). Road safety generally depends on humans, vehicles, and highway conditions. These factors influence road safety separately or in combination. One of the basic means to improve road safety is to reduce hazardous conditions of roads. The main objective of this study is to identify and rank hazardous locations and propose appropriate simple and inexpensive countermeasures along Hawassa-Shashemene-Bulbula main two-lane rural road. Accordingly, the road and traffic data were collected from field investigation and Ethiopian Road Authority and accident data were gathered from police stations. Then, the study road equally divided into short sections of 1.5 km and traffic volume and accident frequencies assigned for each road site to predict theoretical frequencies of accident. Empirical Bayes method and Safety Performance Function have been used to estimate an index known as Potential for Safety Improvement (PSI) for each site of the study area to identify and rank road sites. The result showed that out of 43 road segments 22 of them were identified as dangerous road segments. Moreover, based on further criterion established for screening the ranked road sections 8 road segments were found the most dangerous road segments as they have contributed 76% of total PSI values. The degree of haphazardness of a given road segment in the study area has directly associated with the availability of risk indicating road and traffic factors. Finally, it recommends that regulatory body of road safety in the study area should give high priority and immediate response for the improvement of most dangerous road segments.展开更多
Road safety performance function(SPF) analysis using data-driven and nonparametric methods, especially recent developed deep learning approaches, has gained increasing achievements. However, due to the learning mechan...Road safety performance function(SPF) analysis using data-driven and nonparametric methods, especially recent developed deep learning approaches, has gained increasing achievements. However, due to the learning mechanisms are hidden in a"black box" in deep learning, traffic features extraction and intelligent importance analysis are still unsolved and hard to generate.This paper focuses on this problem using a deciphered version of deep neural networks(DNN), one of the most popular deep learning models. This approach builds on visualization, feature importance and sensitivity analysis, can evaluate the contributions of input variables on model's "black box" feature learning process and output decision. Firstly, a visual feature importance(Vi FI) method that describes the importance of input features is proposed by adopting diagram and numerical-analysis. Secondly,by observing the change of weights using Vi FI on unsupervised training and fine-tuning of DNN, the final contributions of input features are calculated according to importance equations for both steps that we proposed. Sequentially, a case study based on a road SPF analysis is demonstrated, using data collected from a major Canadian highway, Highway 401. The proposed method allows effective deciphering of the model's inner workings and allows the significant features to be identified and the bad features to be eliminated. Finally, the revised dataset is used in crash modeling and vehicle collision prediction, and the testing result verifies that the deciphered and revised model achieves state-of-theart performance.展开更多
Safety performance functions(SPFs),or crash-prediction models,have played an important role in identifying the factors contributing to crashes,predicting crash counts and identifying hotspots.Since a great deal of tim...Safety performance functions(SPFs),or crash-prediction models,have played an important role in identifying the factors contributing to crashes,predicting crash counts and identifying hotspots.Since a great deal of time and effort is needed to estimate an SPF,previous studies have sought to determine the transferability of particular SPFs;that is,the extent to which they can be applied to data from other regions.Although many efforts have been made to examine micro-level SPF transferability,few studies have focused on macro-level SPF transferability.There has been little transferability analysis of macro-level SPFs in the international context,especially between western countries.This study therefore evaluates the transferability of SPFs for several states in the USA(Illinois,Florida and Colorado)and for Italy.The SPFs were developed using data from counties in the United States and provincias in Italy,and the results revealed multiple common significant variables between the two countries.Transferability indexes were then calculated between the SPFs.These showed that the Italy SPFs for total crashes and bicycle crashes were transferable to US data after calibration factors were applied,whereas the US SPFs for total and bicycle crashes,with the exception of the Colorado SPF,could not be transferred to the Italian data.On the other hand,none of the pedestrian SPFs developed was transferable to other countries.This paper provides insights into the applicability of macro-level SPFs between the USA and Italy,and shows a good potential for international SPF transferability.Nevertheless,further investigation is needed of SPF transferability between a wider range of countries.展开更多
In order to improve the prediction precision of the safety performance function （SPF） of freeway basic segments, design and crash data of 640 segments are collected from different institutions. Three negative binomi...In order to improve the prediction precision of the safety performance function （SPF） of freeway basic segments, design and crash data of 640 segments are collected from different institutions. Three negative binomial （NB） regression models and three generalized negative binomial （GNB） regression models are built to prove that the interactive influence of explanatory variables plays an important role in fitting goodness. The effective use of the GNB model in analyzing the interactive influence of explanatory variables and predicting freeway basic segments is demonstrated. Among six models, the two models （one is the NB model and the other is the GNB model. ） which consider the interactive influence of the annual average daily traffic （AADT） and length are more reasonable for predicting results. Furthermore, a comprehensive study is carried out to prove that when considering the interactive influence, the NB and GNB models have almost the same fitting performance in estimating the crashes, among which the GNB model is slightly better for prediction performance.展开更多
文摘A medical device is an instrument that includes components,parts,or accessories to diagnose or treat patients.Since the complexity of medical devices has increased in recent years,functional safety and basic safety are required to ensure the overall device safety.Functional safety is part of the overall safety that relates to the equipment under control(EUC)and to the EUC control system that depends on the correct functionality of the electrical/electronic/programmable electronic(E/E/PE)safety-related systems.This study proposes approach methods to functional safety of medical devices for which it is important to correctly identify the safety functions and the safety integrity level(SIL).The relationship between the functional safety and essential performance is identified focusing on the safety function.The essential performance of E/E/PE systems is defined as the safety function of the functional safety.The target SIL of the essential performance is determined according to the potential risk levels,based on the classification rules of medical devices.This approach is applied to the pulse oximeter as a case study.The target SIL for the functionality of the power-failure alarm condition is determined to be SIL1.The target SILs of other functions are determined as SIL2.
文摘According to the study made by United Nation Economic Commission for Africa, Ethiopia stands as one of the worst countries with respect to road safety performance in terms of traffic accident fatalities per 10,000 vehicles (i.e. 95 in 2007/8). Road safety generally depends on humans, vehicles, and highway conditions. These factors influence road safety separately or in combination. One of the basic means to improve road safety is to reduce hazardous conditions of roads. The main objective of this study is to identify and rank hazardous locations and propose appropriate simple and inexpensive countermeasures along Hawassa-Shashemene-Bulbula main two-lane rural road. Accordingly, the road and traffic data were collected from field investigation and Ethiopian Road Authority and accident data were gathered from police stations. Then, the study road equally divided into short sections of 1.5 km and traffic volume and accident frequencies assigned for each road site to predict theoretical frequencies of accident. Empirical Bayes method and Safety Performance Function have been used to estimate an index known as Potential for Safety Improvement (PSI) for each site of the study area to identify and rank road sites. The result showed that out of 43 road segments 22 of them were identified as dangerous road segments. Moreover, based on further criterion established for screening the ranked road sections 8 road segments were found the most dangerous road segments as they have contributed 76% of total PSI values. The degree of haphazardness of a given road segment in the study area has directly associated with the availability of risk indicating road and traffic factors. Finally, it recommends that regulatory body of road safety in the study area should give high priority and immediate response for the improvement of most dangerous road segments.
基金supported by the National Science and Engineering Research Council of Canada(NSERC)Ontario Research Fund–Research Excellence(ORF-RE)+3 种基金the Ministry of Transportation Ontario(MTO)through Its Highway Infrastructure Innovation Funding Program(HIIFP)Beijing Postdoctoral Science Foundation(ZZ-2019-65)Beijing Chaoyang District Postdoctoral Science Foundation(2019ZZ-45)Beijing Municipal Education Commission(KM201811232016)。
文摘Road safety performance function(SPF) analysis using data-driven and nonparametric methods, especially recent developed deep learning approaches, has gained increasing achievements. However, due to the learning mechanisms are hidden in a"black box" in deep learning, traffic features extraction and intelligent importance analysis are still unsolved and hard to generate.This paper focuses on this problem using a deciphered version of deep neural networks(DNN), one of the most popular deep learning models. This approach builds on visualization, feature importance and sensitivity analysis, can evaluate the contributions of input variables on model's "black box" feature learning process and output decision. Firstly, a visual feature importance(Vi FI) method that describes the importance of input features is proposed by adopting diagram and numerical-analysis. Secondly,by observing the change of weights using Vi FI on unsupervised training and fine-tuning of DNN, the final contributions of input features are calculated according to importance equations for both steps that we proposed. Sequentially, a case study based on a road SPF analysis is demonstrated, using data collected from a major Canadian highway, Highway 401. The proposed method allows effective deciphering of the model's inner workings and allows the significant features to be identified and the bad features to be eliminated. Finally, the revised dataset is used in crash modeling and vehicle collision prediction, and the testing result verifies that the deciphered and revised model achieves state-of-theart performance.
文摘Safety performance functions(SPFs),or crash-prediction models,have played an important role in identifying the factors contributing to crashes,predicting crash counts and identifying hotspots.Since a great deal of time and effort is needed to estimate an SPF,previous studies have sought to determine the transferability of particular SPFs;that is,the extent to which they can be applied to data from other regions.Although many efforts have been made to examine micro-level SPF transferability,few studies have focused on macro-level SPF transferability.There has been little transferability analysis of macro-level SPFs in the international context,especially between western countries.This study therefore evaluates the transferability of SPFs for several states in the USA(Illinois,Florida and Colorado)and for Italy.The SPFs were developed using data from counties in the United States and provincias in Italy,and the results revealed multiple common significant variables between the two countries.Transferability indexes were then calculated between the SPFs.These showed that the Italy SPFs for total crashes and bicycle crashes were transferable to US data after calibration factors were applied,whereas the US SPFs for total and bicycle crashes,with the exception of the Colorado SPF,could not be transferred to the Italian data.On the other hand,none of the pedestrian SPFs developed was transferable to other countries.This paper provides insights into the applicability of macro-level SPFs between the USA and Italy,and shows a good potential for international SPF transferability.Nevertheless,further investigation is needed of SPF transferability between a wider range of countries.
基金The National Natural Science Foundation of China(No.51408229,51278202)the Program of the Key Laboratory of Road and Traffic Engineering of the Ministry of Education,Tongji University(No.K201204)the Science and Technology Program of Guangdong Communication Department(No.2013-02-068)
文摘In order to improve the prediction precision of the safety performance function （SPF） of freeway basic segments, design and crash data of 640 segments are collected from different institutions. Three negative binomial （NB） regression models and three generalized negative binomial （GNB） regression models are built to prove that the interactive influence of explanatory variables plays an important role in fitting goodness. The effective use of the GNB model in analyzing the interactive influence of explanatory variables and predicting freeway basic segments is demonstrated. Among six models, the two models （one is the NB model and the other is the GNB model. ） which consider the interactive influence of the annual average daily traffic （AADT） and length are more reasonable for predicting results. Furthermore, a comprehensive study is carried out to prove that when considering the interactive influence, the NB and GNB models have almost the same fitting performance in estimating the crashes, among which the GNB model is slightly better for prediction performance.
