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基于MRI下咽癌咽后淋巴结转移高危因素研究 被引量:4
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作者 王惠丽 曲媛 +10 位作者 王凯 吴润叶 刘清峰 张烨 张世平 肖建平 易俊林 高黎 徐国镇 罗京伟 黄晓东 《中华放射肿瘤学杂志》 CSCD 北大核心 2020年第8期625-628,共4页
目的基于MRI技术分析下咽鳞状细胞癌咽后区域淋巴结转移率和高危影响因素,以指导临床靶区勾画。方法搜集中国医学科学院肿瘤医院2012-2018年间的下咽癌患者的临床资料,入组的患者需经病理确诊,并且在所有治疗前接受了头颈部MRI检查,并... 目的基于MRI技术分析下咽鳞状细胞癌咽后区域淋巴结转移率和高危影响因素,以指导临床靶区勾画。方法搜集中国医学科学院肿瘤医院2012-2018年间的下咽癌患者的临床资料,入组的患者需经病理确诊,并且在所有治疗前接受了头颈部MRI检查,并且其淋巴结转移诊断、临床靶区勾画都经过全科查房讨论审核确定。通过建立受试者工作特征曲线找到原发灶体积GTVp及淋巴结体积GTVnd的最佳界值,将患者区分为高GTVp组、低GTVp和高GTVnd组、低GTVnd组后,纳入患者出现咽后区域LNM的高危因素分析,分别用χ2检验和Logistic回归模型行单因素和多因素分析。结果最终纳入患者326例,所有患者颈部淋巴结转移率为90.5%,最常见的区域为Ⅱa区,其次为Ⅲ、Ⅱb、Ⅳ、Ⅶa(咽后)、Ⅴ区。咽后淋巴结转移率为21.5%,原发灶位于咽后壁患者中咽后淋巴结转移率为53.1%。单因素和多因素分析表明肿瘤原发于咽后壁、双侧颈部淋巴结转移、GTVp>47 cm3、GTVnd>22 cm3与咽后淋巴结转移显著相关(P值为0.002、0.020、0.003、0.023)。结论下咽癌咽后淋巴结转移发生率较高,尤其是原发灶位于咽后壁患者。同时具有双侧颈部淋巴结转移、较大肿瘤负荷患者容易出现咽后淋巴结转移。对于具有以上高危因素患者推荐临床靶区勾画时将咽后淋巴结引流区包括在内。 展开更多
关键词 下咽肿瘤 淋巴结转移 咽后 高危因素
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Ultrasound-guided fine needle aspiration of retropharyngeal lymph nodes after radiotherapy for nasopharyngeal carcinoma: a novel technique for accurate diagnosis 被引量:3
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作者 Long-Jun He Chuanbo Xie +13 位作者 Yin Li Lin-Na Luo Ke Pan Xiao-Yan Gao Li-Zhi Liu Jian-Ming Gao Guang-Yu Luo Hong-Bo Shan Ming-Yuan Chen Chong Zhao Wei-Jun Fan Ping Yang Guo-Liang Xu Jian-Jun Li 《Cancer Communications》 SCIE 2018年第1期229-236,共8页
Background:Enlarged retropharyngeal lymph nodes(RLNs)are very common in patients with nasopharyngeal carcinoma(NPC)undergoing radiotherapy.The most suitable treatment option for enlarged RLNs depends on the pathologic... Background:Enlarged retropharyngeal lymph nodes(RLNs)are very common in patients with nasopharyngeal carcinoma(NPC)undergoing radiotherapy.The most suitable treatment option for enlarged RLNs depends on the pathological results.However,RLN sampling is difficult and imminent in the clinic setting.We recently developed a novel minimally invasive technique termed endoscopic ultrasound-guided fine needle aspiration(EUS-FNA)for sam-pling RLN tissues sufficient for pathological or cytological diagnosis.Methods:We enrolled 30 post-radiotherapy patients with NPC with suspected RLN metastasis detected via mag-netic resonance imaging(MRI).The EUS probe was introduced into the nasopharynx via the nostrils,and EUS was then used to scan the retropharyngeal space and locate the RLN in the anterior carotid sheath.EUS-FNA was subsequently performed.The safety and efficacy of using EUS-FNA to sample the RLN tissues were assessed.Results:Strips of tissue were successfully sampled from all patients using EUS-FNA.Of the 30 patients,23 were confirmed to have cancer cells in the biopsied tissues via pathology or cytology examinations with 1 EUS-FNA biopsy session.The seven cases without confirmed cancer cells were subsequently reanalyzed by using another EUS-FNA biopsy session,and two more cases were confirmed possessing cancer cells.The other five patients without con-firmed cancer cells were closely followed with MRI every month for 3 months.After follow-up for 3 months,three patients were still considered cancer-free due to the presence of RLNs with stable or shrinking diameters.The rest two patients who showed progressive disease underwent a third EUS-FNA biopsy procedure and were further confirmed to be cancer cell-positive.In the whole cohort reported here,the EUS-FNA procedure was not associated with any severe complications.Conclusion:EUS-FNA is a safe and effective diagnostic approach for sampling tissues from the RLNs in patients with suspected recurrent NPC. 展开更多
关键词 Fine needle aspiration Endoscopic ultrasonography retropharyngeal lymph node Nasopharyngeal carcinoma
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Kawasaki disease with retropharyngeal edema: case series from a single center experience 被引量:3
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作者 Dennis Chi Yu Au Nai Chung Fong Yat Wah Kwan 《Chinese Medical Journal》 SCIE CAS CSCD 2019年第14期1753-1754,共2页
To the Editor:Kawasaki disease (KD) and its classical diagnostic criteria are well known to pediatricians nowadays.However,KD can present with substantial overlap of clinical picture with many infectious diseases.Rece... To the Editor:Kawasaki disease (KD) and its classical diagnostic criteria are well known to pediatricians nowadays.However,KD can present with substantial overlap of clinical picture with many infectious diseases.Recently it is increasingly recognized that KD can present as pyogenic abscess-like formation with retropharyngeal edema (RPE).As estimated by Yoskovitch et al,[1] 5% of KD presented with some forms of deep neck infection.They could be in various forms,such as peritonsillar abscess,parapharyngeal or retropharyngeal abscess-like edema or acute mastoiditis.Not only do they mimic retropharyngeal abscess clinically,some with incomplete presentation may also contribute to delayed diagnosis and hence timely treatment.In this case series,we reported our experience in managing 24 cases of KD presenting with RPE. 展开更多
关键词 KAWASAKI DISEASE retropharyngeal EDEMA DELAYED diagnosis
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Tuberculous retropharyngeal abscess without cervical spine TB
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作者 Chandrakant Patil Rashmi Kharat(Patil) +2 位作者 Prasad Deshmukh Sameer Singhal Blenda D'Souza 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2011年第3期251-252,共2页
Tuberculous retropharyngeal abscess is a rare presentation.It is present in adults usually due to involvement of cervical spine by tuberculosis.Retropharyngeal space usually gets involved in children due to pyogenic o... Tuberculous retropharyngeal abscess is a rare presentation.It is present in adults usually due to involvement of cervical spine by tuberculosis.Retropharyngeal space usually gets involved in children due to pyogenic organisms or secondary to trauma.Here is a case of tuberculous retropharyngeal abscess in an adult female,with pulmonary tuberculosis.The patient was not having tuberculous involvement of cervical spine and was managed surgically by aspirating the retropharyngeal abscess transorally and AKT Category I. 展开更多
关键词 TUBERCULOUS retropharyngeal ABSCESS ASPIRATION
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Retropharyngeal emphysema: An unusual aetiology—A case report and literature review
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作者 Daniel Adekunle Onakoya Paul Adekunle 《Case Reports in Clinical Medicine》 2013年第3期194-197,共4页
Introduction: Retropharyngeal emphysema is a potentially life threatening condition which may require urgent diagnosis and intervention. It has been documented to occur following trauma to the aerodigestive tract and ... Introduction: Retropharyngeal emphysema is a potentially life threatening condition which may require urgent diagnosis and intervention. It has been documented to occur following trauma to the aerodigestive tract and is usually accompanied by subcutaneous emphysema of the cervical region. This condition may be complicated by mediastinal emphysema and pneumomediastinum. Foreign body ingestion is quite common in little children and in this environment;a cultural practice is for mothers or other caregivers to attempt to remove these foreign bodies by forcing their finger(s) down the oropharynx and Hypopharynx of these young children. This usually results in injuries to these anatomical sites. Retropharyngeal emphysema complicating this practice is rarely reported. Case presentation: We present the case of a 4-year-old Nigerian boy who presented with stridor and severe dyspnoea following repeated attempts at removal of a purportedly ingested foreign body by his mother. Examination revealed oedema of the soft palate with small multiple bleeding shallow lacerations of the oropharyngeal walls. Oxygen therapy was commenced and preparations for urgent upper airway intervention made. Soft tissue neck X-ray revealed retropharyngeal and subcutaneous emphysema with upper airway compromise. Conservative treatment with high dose steroids and antibiotics led to a gradual resolution of the condition. Conclusion: This is a rarely reported complication of this relatively common socio-cultural “foreign body removal method”. Public awareness is required to stop this potentially life threatening practice. 展开更多
关键词 retropharyngeal EMPHYSEMA FOREIGN BODY FOREIGN BODY Removal
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Traumatic Retropharyngeal Abscess of Insidious Onset—A Case Report and Literature Review
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作者 Shuaib Kayode Aremu 《Case Reports in Clinical Medicine》 2019年第4期57-61,共5页
Retropharyngeal abscess is an abscess of the deep spaces in the neck which if not treated urgently can be life-threatening as a result of airway compromise. It is important to detect and treat very early. It may arise... Retropharyngeal abscess is an abscess of the deep spaces in the neck which if not treated urgently can be life-threatening as a result of airway compromise. It is important to detect and treat very early. It may arise in pediatrics from direct neck trauma which is not very common and fishbone impaction. Direct anterior neck trauma resulting in insidious retropharyngeal abscess has not been widely reported. 展开更多
关键词 retropharyngeal ABSCESS TRAUMA NECK Spaces
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Upper Cervical Spine Infection. Complication of Hypopharyngeal Injury
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作者 Ghassan Skaf Elias Elias 《International Journal of Otolaryngology and Head & Neck Surgery》 2016年第2期96-102,共7页
Background: We describe a rare case of Candida albicans retropharyngeal infection with upper cervical spondylodiscitis associated with epidural abscess triggered by ingestion of a chicken bone. Case Description: A 63-... Background: We describe a rare case of Candida albicans retropharyngeal infection with upper cervical spondylodiscitis associated with epidural abscess triggered by ingestion of a chicken bone. Case Description: A 63-year-old woman presented with posterior neck and bilateral shoulders pain three weeks after choking on a 2-centimeter chicken bone. Magnetic resonance imaging (MRI) revealed spondylodiscitis and epidural abscess with significant spinal cord compression at C2 and C3 levels. A Barium swallow showed a focal disruption of the posterior wall of the esophagus. A posterior upper cervical fixation (C2-C5) was initially performed. One week later an anterior decompressive procedure was carried out followed by iliac crest bony fusion, and repair of the esophageal defect. Intra-operative cultures showed heavy growth of Candida albicans. After a transitory post-operative neurologic worsening, and after six weeks of appropriate antifungal therapy, the patient achieved a full clinical and radiologic recovery. Conclusion: Prompt surgical debridement, fusion and stabilization combined with adequate antimicrobial agents are necessary to guarantee a good outcome and reverse the neurological deficits. 展开更多
关键词 OSTEOMYELITIS Cervical Spine DISCITIS retropharyngeal Abscess Candida albicans
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Spontaneous Retropharyngeal Haematoma in a One-Year-Old Child: A Case Report
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作者 R. K. Mundra Richi Sinha Sunil Bajoliya 《Case Reports in Clinical Medicine》 2014年第5期272-275,共4页
Spontaneous retropharyngeal haematoma is an unusual condition and difficult to diagnosis early especially in infants. It has multiple aetiological factors and can present to a number of specialists including the otola... Spontaneous retropharyngeal haematoma is an unusual condition and difficult to diagnosis early especially in infants. It has multiple aetiological factors and can present to a number of specialists including the otolaryngologist. We describe an unusual case of a spontaneous huge retropharyngeal haematoma in 1-year-old male child which demonstrates the dramatic presentation and emphasizes the need for immediate surgical approach. 展开更多
关键词 CERVICAL HAEMATOMA Prevertebral retropharyngeal
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Retropharyngeal abscess presenting as acute airway obstruction in a 66-year-old woman: A case report
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作者 Jian Lin Xiao-Mai Wu +1 位作者 Jia-Xi Feng Mei-Fang Chen 《World Journal of Clinical Cases》 SCIE 2019年第22期3838-3843,共6页
BACKGROUND Adult retropharyngeal abscess(RPA)is extremely rare,and most cases reported in the literature were related to tuberculous infection.We present a case of RPA with acute airway obstruction as the main manifes... BACKGROUND Adult retropharyngeal abscess(RPA)is extremely rare,and most cases reported in the literature were related to tuberculous infection.We present a case of RPA with acute airway obstruction as the main manifestation in a 66-year-old woman that was considered to be non-tubercular suppurative inflammation in the retropharyngeal space.CASE SUMMARY A 66-year-old woman complaining of chills and fever was admitted to our hospital.She was initially diagnosed with an acute upper respiratory tract infection.She lost consciousness twice during hospitalization.She regained consciousness immediately upon emergency tracheal intubation.Acute upper airway obstruction was suspected as arterial blood gas analysis showed obvious acute retention of carbon dioxide before the second tracheal intubation.The diagnosis of RPA was confirmed by computed tomography and magnetic resonance imaging.Kocuria kristinae was isolated from blood samples taken from both hands.The patient recovered and was subsequently discharged after receiving antibiotic therapy together with surgical incision and drainage of the abscess.CONCLUSION Clinicians should be alert to the possibility of RPA in patients with acute airway obstruction.Surgical incision and drainage is an effective treatment for RPA. 展开更多
关键词 retropharyngeal ABSCESS AIRWAY OBSTRUCTION Kocuria kristinae INTUBATION Surgery Case report
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Giant Retropharyngeal Abscess in a Nigerian Adult Following Fish Bone Throat Injury
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作者 Stanley B. Amutta Daniel Aliyu +2 位作者 Mohammed Abdullahi Mohammed Danfulani Yunusa A. Mufutau 《International Journal of Otolaryngology and Head & Neck Surgery》 2013年第6期271-275,共5页
Retropharyngeal abscess (RPA) is an uncommon disease entity that typically occurs in children under 5 years of age, which has the potential to cause upper airway obstruction. Upper respiratory tract infection is the m... Retropharyngeal abscess (RPA) is an uncommon disease entity that typically occurs in children under 5 years of age, which has the potential to cause upper airway obstruction. Upper respiratory tract infection is the most common predisposing factor to RPA in children while cervical spine tuberculosis and trauma are the major aetiological factors in the adult. We report a case of a 21-year-old Nigerian farmer with giant retropharyngeal abscess following fish bone throat injury causing life-threatening upper airway obstruction. The patient responded well to emergency tracheostomy, intraoral surgical drainage and empirical antibiotic therapy. We highlight the diagnostic and therapeutic challenges of managing such a patient. 展开更多
关键词 GIANT retropharyngeal ABSCESS Fish Bone TRACHEOSTOMY Antibiotic INTRA-ORAL Drainage
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川崎病并发咽旁间隙炎性改变1例报告及文献复习 被引量:1
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作者 苏松 王洪波 +3 位作者 马瑜聪 方昕 刘俊荣 乔红梅 《吉林大学学报(医学版)》 CAS CSCD 北大核心 2022年第1期228-233,共6页
目的:探讨以并发咽旁间隙和咽后间隙炎性改变为主要表现的川崎病患儿的临床特征、诊疗和预后,以提高临床医生对该病的认识。方法:回顾分析2019年11月于本科住院的1例以咽旁间隙受累为主要表现的川崎病患儿的临床资料,并对既往文献进行... 目的:探讨以并发咽旁间隙和咽后间隙炎性改变为主要表现的川崎病患儿的临床特征、诊疗和预后,以提高临床医生对该病的认识。方法:回顾分析2019年11月于本科住院的1例以咽旁间隙受累为主要表现的川崎病患儿的临床资料,并对既往文献进行复习总结,分析川崎病并发头颈部症状患者的临床表现和影像学检查特征。结果:患儿,男性,3岁,因发热8 d伴颈部活动受限和斜颈2 d入院。查体,躯干部可见红色斑丘疹,颈部淋巴结肿大,结膜充血,口唇红,杨梅舌,手足硬肿,血常规中白细胞总数和C反应蛋白(CRP)明显升高,病程第20天四肢末端出现典型膜状脱皮,明确诊断为川崎病。患儿入院时伴有颈部活动受限和斜颈,影像学检查提示鼻咽和口咽右侧咽旁间隙肿物,给予抗生素及退热对症治疗无效,应用丙种球蛋白和阿司匹林治疗后,患儿颈部活动受限和斜颈表现消失,川崎病症状体征好转,实验室检查炎性指标逐渐恢复正常,复查颈部MRI提示咽旁间隙炎性改变较前明显减小。结论:头颈部异常表现可以作为川崎病的早期症状出现,易误诊为化脓性淋巴结炎或咽旁及咽后部化脓性感染。川崎病并发咽旁间隙或者咽后间隙炎性改变应尽早进行正确诊断和治疗,避免出现心血管系统损害以及行不必要的手术治疗。 展开更多
关键词 川崎病 咽旁间隙 咽后间隙 炎症 丙种球蛋白
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低温等离子射频消融联合博来霉素治疗咽后间隙淋巴管瘤 被引量:1
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作者 李万鹏 李晓艳 《中国中西医结合耳鼻咽喉科杂志》 2017年第4期285-288,共4页
目的探讨咽后间隙淋巴管瘤的诊断与治疗。方法采用低温等离子射频消融联合博来霉素治疗咽后间隙淋巴管瘤,分析临床资料并复习相关文献。结果该方法容易操作,术中出血少,不易损伤正常的组织结构,能够减少手术时间,明显改善临床症状,术后... 目的探讨咽后间隙淋巴管瘤的诊断与治疗。方法采用低温等离子射频消融联合博来霉素治疗咽后间隙淋巴管瘤,分析临床资料并复习相关文献。结果该方法容易操作,术中出血少,不易损伤正常的组织结构,能够减少手术时间,明显改善临床症状,术后无明显并发症,术后随访6个月均无复发情况。结论淋巴管瘤发生于咽后间隙属于罕见,目前国内外报道的案例很少,对其治疗的方法尚无定论,本研究采用低温等离子射频消融联合博来霉素治疗具有良好的疗效,值得在临床上推广。 展开更多
关键词 低温等离子射频消融 博来霉素 淋巴管瘤 咽后间隙
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Magnetic Resonance Imaging of Retropharyngeal Lymphadenopathy in Nasopharyngeal Carcinoma
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作者 Chunyan Cui Xuewen Liu 《Chinese Journal of Clinical Oncology》 CSCD 2007年第1期42-47,共6页
OBJECTIVE The aim of our study was to document the patterns of RLN spread by using MRI. METHODS The MR images of 294 patients with newly diagnosed NPC were reviewed retrospectively. Criteria for metastatic lymph nodes... OBJECTIVE The aim of our study was to document the patterns of RLN spread by using MRI. METHODS The MR images of 294 patients with newly diagnosed NPC were reviewed retrospectively. Criteria for metastatic lymph nodes included: shortest axial diameter, nodal necrosis, extracapsular spread, and a contrast enhancing rim. RESULTS RLN involvement was detected in 190 (64.6%) patients. A significantly higher incidence of metastatic RLNs was observed in patients with involvement of the oropharynx, nasal cavity, pre-styloid parapharyngeal space, post-styloid parapharyngeal space, levator muscle of the velum palatini, and tensor muscle of the velum palatine. Patients with level Ⅱ,Ⅲ, and Ⅴ node involvement also had a higher incidence of metastatic RLNs. Of the 231 patients who had metastatic RLNs or cervical lymph nodes, 43 (18.6%) had only metastatic RLNs, 41 (17.7%) had only metastatic cervical lymph nodes, and 147 (63.6%) exhibited an involvement of both the RLNs and cervical lymph nodes. The difference between the incidence of RLN involvements (82.3%) and the incidence of cervical lymph node involvement (81.4%) was very small. CONCLUSION Metastatic RLNs are significantly associated with early stage primary tumor involvement and supper cervical lymph node metastasis in NPC. 展开更多
关键词 cervical lymph nodes magnetic resonance imaging nasopharyngeal carcinoma retropharyngeal lymph nodes.
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双侧咽后颈内动脉一例
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作者 赵宏伟 陆忠烈 《中华解剖与临床杂志》 2018年第5期404-405,共2页
患者女,79岁。因“突发言语不清,左侧肢体乏力2d”门诊拟“急性脑梗死”收住入院。患者既往有高血压病史3年,自述服药控制良好;无糖尿病、高脂血症病史。查体:神志清楚,血压160/71mmHg(1mmHg=0.133kPa),心率78次/分,律齐;眼球活动正常,... 患者女,79岁。因“突发言语不清,左侧肢体乏力2d”门诊拟“急性脑梗死”收住入院。患者既往有高血压病史3年,自述服药控制良好;无糖尿病、高脂血症病史。查体:神志清楚,血压160/71mmHg(1mmHg=0.133kPa),心率78次/分,律齐;眼球活动正常,左侧鼻唇沟变浅,口角向右歪斜,伸舌偏左,颈软,左侧肌力4级、右侧肌力5级,病理征未引出,深浅感觉未见明显异常,美国国立卫生研究院卒中量表评分5分,洼田饮水试验4级。 展开更多
关键词 颈内动脉 咽后 CT血管造影 遗传变异
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Submandibular retropharyngeal cervical vertebra hook-plate for the treatment of C2 vertebral body tumors
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作者 晏怡果 《外科研究与新技术》 2011年第2期121-122,共2页
Objective To evaluate the clinical results of sub-mandibular retropharyngeal cervical vertebrahook-plate (RCHP)reconsruction for the treatment of of C2 vertebral body tumors.Methods Nine patents with C2 vertebral body... Objective To evaluate the clinical results of sub-mandibular retropharyngeal cervical vertebrahook-plate (RCHP)reconsruction for the treatment of of C2 vertebral body tumors.Methods Nine patents with C2 vertebral body tumors 展开更多
关键词 BODY Submandibular retropharyngeal cervical vertebra hook-plate for the treatment of C2 vertebral body tumors
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Management of pediatric peritonsillar and deep neck infections-cross-sectional retrospective analysis
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作者 Ana Sousa Menezes Daniela Correia Ribeiro +2 位作者 Joana Rocha Guimar(a)es António Fontes Lima Luís Dias 《World Journal of Otorhinolaryngology-Head and Neck Surgery》 2019年第4期207-214,共8页
Objective:Deep neck infections(DNI)are responsible for significant morbidity in children and healthcare expenditures.Few studies exist specifically addressing the clinical and epidemiologic characterization and manage... Objective:Deep neck infections(DNI)are responsible for significant morbidity in children and healthcare expenditures.Few studies exist specifically addressing the clinical and epidemiologic characterization and management of DNI's in the pediatric population.Our goal was to analyse the demographic characteristics,clinical presentation,diagnostic and therapeutic approaches of peritonsillar and DNI in pediatric patients.Methods:The medical records of patients,aged up to 18 years,admitted for peritonsillar and DNI at our department,from 2011 to 2016,were retrospectively reviewed and compared with the literature available.Ninety-eight patients were enrolled.Results:The mean age was higher in patients with peritonsillar abscess and lower in patients with retropharyngeal and parapharyngeal infections.Admissions have significantly increased from 2011.There was a seasonal variation for DNI incidence,with a peak incidence in Summer and Spring.All patients included were treated as inpatient and received empirical intravenous antibiotic therapy and steroids regardless of drainage procedures.Incision and drainage was performed in 72 patients.The hospital length of stay was higher among patients with retropharyngeal abscess and in the group with complications.Only 2 patients developed complications during hospital stay.The most common microbiological pattern was monomicrobial and the most commonly isolated pathogens were Streptococcus Pyogenes,Streptococcus Mitisand anaerobic bacteria.Conclusions:Surgical incision and drainage followed by intravenous antibiotic and steroids proved to be successfull with low morbidity related to surgical approach.However,in selected cases,medical therapy may be an alternative to surgical management in uncomplicated infections. 展开更多
关键词 Deep neck infection ABSCESS Peritonsillar PARAPHARYNGEAL retropharyngeal MICROBIOLOGY Epidemiology
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Surgical treatment of delayed cervical infection and incomplete quadriplegia with fish-bone ingestion:A case report
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作者 Suo-Yuan Li Ye Miao +5 位作者 Liang Cheng Ye-Feng Wang Zhi-Qiang Li Yu-Bo Liu Tian-Ming Zou Jun Shen 《World Journal of Clinical Cases》 SCIE 2021年第25期7535-7541,共7页
BACKGROUND The most commonly ingested foreign body in Asians is fish bone.The vast majority of patients have obvious symptoms and can be timely diagnosed and treated.Cases of pyogenic cervical spondylitis and diskitis... BACKGROUND The most commonly ingested foreign body in Asians is fish bone.The vast majority of patients have obvious symptoms and can be timely diagnosed and treated.Cases of pyogenic cervical spondylitis and diskitis with retropharyngeal and epidural abscess resulting in incomplete quadriplegia due to foreign body ingestion have been rarely reported.The absence of pharyngeal or esophageal discomfort and negative computed tomography(CT)findings of fish bone have not been reported.We report the case of an elderly female patient with delayed cervical infection and incomplete quadriplegia who had a history of fish bone ingestion.CASE SUMMARY A 73-year-old woman presented with right neck pain and weakness of four limbs for a week,and had a history of fish bone ingestion and negative findings on laryngoscopic examination one month previously.She did not complain of any pharyngeal or esophageal discomfort.Cervical magnetic resonance imaging showed C4/C5 spondylitis and diskitis along with retropharyngeal and ventral epidural abscesses.No sign of fish bone was detected on lateral cervical radiography and CT scans.The muscle strength of the patient’s right lower limb receded to grade 1 and other limbs to grade 2 suddenly on the 10th day of hospitalization.Emergency surgery was performed to drain the abscess and decompress the spinal cord by removing the anterior inflammatory necrotic tissue.Simultaneously,flexible esophagogastroduodenoscopy was carried out and a hole in the posterior pharyngeal wall was found.The motor weakness of the right lower limb improved to grade 3 and the other limbs to grade 4 within 2 d postoperatively.CONCLUSION This rare case highlights the awareness of the posterior pharyngeal or esophageal wall perforation in patients with cervical pyogenic spondylitis along with a history of fish bone ingestion,even though local discomfort symptoms are absent and the radiological examinations are negative. 展开更多
关键词 Fish bone Cervical infection Pyogenic spondylitis retropharyngeal abscess Epidural abscess Case report
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颈深部脓肿50例临床分析 被引量:73
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作者 郑艳 文定厚 乔晓明 《中华耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2005年第1期60-63,共4页
目的 探讨颈深部脓肿患者的临床表现、微生物学、影像学及治疗经验。方法 对 1997年 1月— 2 0 0 2年 12月收治的 5 0例颈深部脓肿患者的临床资料进行了回顾性分析。结果 颈深部脓肿的感染来源有 :牙源性 3例 ,急性化脓性扁桃体炎及... 目的 探讨颈深部脓肿患者的临床表现、微生物学、影像学及治疗经验。方法 对 1997年 1月— 2 0 0 2年 12月收治的 5 0例颈深部脓肿患者的临床资料进行了回顾性分析。结果 颈深部脓肿的感染来源有 :牙源性 3例 ,急性化脓性扁桃体炎及喉炎 8例 ,上呼吸道感染 9例 ,咽喉及食道异物14例 ,糖尿病伴感染 5例 ,不明原因 11例。 5 0例中 2 1例作了脓液细菌培养 ,其中 13例 (6 4 % )为阳性。通过采用脓肿切开引流术 ,经颈 纵隔引流术 ,大剂量抗生素等综合治疗 ,5 0例中治愈 4 6例(92 % ) ,死亡 4例 (8% )。死亡原因 :2例为咽旁脓肿致颈部大血管破裂出血死亡 ,1例食道周围脓肿伴消化道大出血死亡 ,1例咽旁脓肿合并糖尿病中毒性休克死亡。结论 颈深部脓肿一经确诊 ,应及时引流 ,合理应用抗生素 ,有效控制其他伴发病。重视对严重并发症的认识及处理 。 展开更多
关键词 颈深部脓肿 抗生素 开胸引流术 CT检查 咽后脓肿
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咽后淋巴结转移在鼻咽癌分期中的意义 被引量:28
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作者 唐玲珑 刘立志 +5 位作者 马骏 宗井凤 黄莹 林爱华 卢泰祥 崔念基 《癌症》 SCIE CAS CSCD 北大核心 2006年第2期129-135,共7页
背景与目的:鼻咽癌咽后淋巴结转移的发生率高,X92分期系统未明确其在临床分期中的意义,本研究旨在分析咽后淋巴结转移对鼻咽癌预后的影响及评价它在鼻咽癌分期中的意义。方法:收集1999年1月至1999年12月间中山大学肿瘤防治中心放疗科收... 背景与目的:鼻咽癌咽后淋巴结转移的发生率高,X92分期系统未明确其在临床分期中的意义,本研究旨在分析咽后淋巴结转移对鼻咽癌预后的影响及评价它在鼻咽癌分期中的意义。方法:收集1999年1月至1999年12月间中山大学肿瘤防治中心放疗科收治的经病理证实、治疗前进行鼻咽和颈部增强CT扫描的初诊鼻咽癌749例。多因素分析采用Cox风险比例模型,根据临床分期的原则,采用风险一致性、风险差异性、预后预测及分布均衡性等指标进行评价。结果:咽后淋巴结转移的发生率为51.5%。T分期、N分期及临床分期晚的患者咽后淋巴结转移发生率分别为57.8%、60.3%和57.9%,高于早期患者的发生率(45.2%、47.6%和38.9%),其差异均有统计学意义(P值分别为0.001、0.001、<0.001)。咽后淋巴结转移患者和无咽后淋巴结转移患者5年总生存率分别为58.7%和72.2%,5年无远处转移生存率分别为74.5%和84.9%,其差异有统计学意义(P均<0.001);多因素分析,咽后淋巴结转移并不是影响鼻咽癌总生存率的独立预后因素,对无远处转移生存率的影响有临界意义(P=0.053)。N0合并咽后淋巴结转移的死亡及远处转移的风险比分别为0.540及0.411,与N1组(0.601及0.555)相似。将其归为N1或T2比较,前者N分期预后的风险一致性较好,但N分期分布极不均衡,N1患者比例达50.2%。后者N分期及临床分期预后的风险差异性明显,且T、N分期及临床分期分布均衡性较好。结论:咽后淋巴结转移对鼻咽癌无远处转移生存率可能有影响,在目前&92分期系统及现行的鼻咽癌原发灶放射治疗模式的情况下,将咽后淋巴结转移归为T2分期内容更符合分期的原则。 展开更多
关键词 鼻咽肿瘤 咽后淋巴结 肿瘤转移 肿瘤分期
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颈深部感染95例临床分析 被引量:23
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作者 程泽星 余爵波 +3 位作者 肖路 练状 魏毅玲 汪俊峰 《中华耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2015年第9期769-772,共4页
目的 总结诊治颈深部感染的经验,探讨影像学评价和选择适当治疗方法的重要性.方法 回顾性分析2006年1月至2015年3月95例颈深部感染患者的临床资料.结果 95例患者的感染来源为急性化脓性扁桃体炎或咽喉炎27例(28.4%),上呼吸道感染23例... 目的 总结诊治颈深部感染的经验,探讨影像学评价和选择适当治疗方法的重要性.方法 回顾性分析2006年1月至2015年3月95例颈深部感染患者的临床资料.结果 95例患者的感染来源为急性化脓性扁桃体炎或咽喉炎27例(28.4%),上呼吸道感染23例(24.2%),牙源性感染或口腔炎症16例(16.8%),咽喉或食管异物9例(9.5%)和急性颈淋巴结炎5例(5.3%),不明原因15例(15.8%);CT检查显示47例患者蜂窝组织炎,48例形成脓肿.咽旁脓肿25例,咽后脓肿9例,颌下间隙脓肿6例,颈前间隙5例,食管周围脓肿3例.并发症:纵隔脓肿2例,心包积液1例,双侧液气胸2例.上消化道大出血1例35例患者行脓液细菌培养,其中21例呈阳性.21例在抗感染治疗同时进行脓肿切开引流术,16例行CT引导下经皮穿刺置管持续引流术,5例行B超下细针穿刺抽脓;4例患者行气管切开,3例患者因出现感染性休克症状转重症监护病房治疗,1例治愈,2例死亡,1例死因为上消化道大出血,1例死因为感染性休克.结论 颈深部感染患者必须首先保证气道通畅.经抗生素治疗无效后应在24 ~48 h内进行引流或手术.影像学检查对诊断颈深部感染及选择合理的治疗方案具有重要意义.细菌培养可为制定更为有效的治疗方案及明确病因提供了可靠依据. 展开更多
关键词 蜂窝织炎 咽后脓肿 脓肿 细菌感染
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