AIM: To summarize the clinical features, systemic associations, risk factors and choroidal thickness (CT) changing in posterior scleritis (PS) with serous retinal detachment.METHODS: This retrospective study included ...AIM: To summarize the clinical features, systemic associations, risk factors and choroidal thickness (CT) changing in posterior scleritis (PS) with serous retinal detachment.METHODS: This retrospective study included 23 patients diagnosed PS with retinal detachment from August 2012 to July 2017. All patients' medical history and clinical features were recorded. The examinations included best corrected visual acuity (BCVA), intraocular pressure (IOP), fundus examination, and routine eye examinations. Posterior coats thickness (PCT) was determined by B-scan ultrasound, the CT was measured by enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) and clinical data were compiled and analyzed.RESULTS: After application of extensive exclusion criteria, 23 patients with PS remained (13 females, 10 males). The average age at presentation was 29.5±9.24 years old. Ocular pain and blurred vision were the two most common complained symptoms by patients. Anterior scleritis occurred in 12 patients, which was confirmed by ultrasound biomicroscopy (UBM) examination. Despite all patients displaying serous retinal detachment in their macula, no fluorescein leakage was observed in the macular area. Optic disc swelling was documented in 10 of the 23 eyes. From B-scan ultrasound examination, the PCT in creased with fluid in Tenon's capsule demonstrated as a typical T-sign. The average PCT was 2.51±0.81 mm in the PS-affected eyes and only 1.09±0.29 mm in the unaffected eye (P<0.0001). The subfoveal CT was 442.61 ±55.61 μm, which correlated with axis length (r=-0.65, P=0.001) and PCT (r=0.783, P<0.001). The BCVA and IOP did not correlate with either CT or PCT.CONCLUSION: PS with serous retinal detachment presented a variety of symptoms, such as pain, visual loss, and physical indicators. Typical T-sign detected by B-scan ultrasound is a useful confirmatory sign for PS diagnosis. Pathological increases in CT might be a potential predictive factor for inflammation.展开更多
目的评价甲强龙联合地塞米松交替球周注射在玻璃体切割术治疗脉络膜脱离型视网膜脱离中的疗效。方法回顾性分析我科2012年1月至2013年12月收治的临床确诊为脉络膜脱离型视网膜脱离的患者共46例46眼。按糖皮质激素的给药途径,分为静脉组...目的评价甲强龙联合地塞米松交替球周注射在玻璃体切割术治疗脉络膜脱离型视网膜脱离中的疗效。方法回顾性分析我科2012年1月至2013年12月收治的临床确诊为脉络膜脱离型视网膜脱离的患者共46例46眼。按糖皮质激素的给药途径,分为静脉组与球周组各23例23眼,均行玻璃体切除+硅油充填术,术后随访12个月以上。对比两组手术前后最佳矫正视力、眼压、术前糖皮质激素使用时间、不良反应发生率、视网膜脱离一次手术复位率、视网膜脱离复发率等。结果静脉组与球周组患者入院时眼压分别为(6.74±2.33)mm Hg(1 k Pa=7.5 mm Hg)和(6.96±1.88)mm Hg,使用糖皮质激素后术前眼压分别为(9.34±1.50)mm Hg和(9.43±1.08)mm Hg;最佳矫正视力入院时分别为2.07±0.14和2.23±0.16,出院时分别为2.02±0.17和2.03±0.14,两组组内比较差异均有统计学意义(均为P<0.05),而组间比较差异均无统计学意义(均为P>0.05)。术后12个月内静脉组与球周组一次性视网膜脱离复位例数分别为19例和21例、视网膜脱离复发例数分别为4例和2例,差异均无统计学意义(均为P>0.05);而两组在术前糖皮质激素使用时间,静脉组为(5.35±0.12)d、球周组为(4.04±0.38)d,差异有统计学意义(t=2.31,P=0.03);糖皮质激素使用不良反应,静脉组为6例、球周组为0例,差异有统计学意义(χ2=6.9,P=0.009)。结论甲强龙联合地塞米松交替球周注射是一种玻璃体切割术治疗脉络膜脱离型视网膜脱离的安全有效的方法。展开更多
基金Supported by the Fund of Natural Science Foundation of Zhejiang Province(No.LY18H120009)
文摘AIM: To summarize the clinical features, systemic associations, risk factors and choroidal thickness (CT) changing in posterior scleritis (PS) with serous retinal detachment.METHODS: This retrospective study included 23 patients diagnosed PS with retinal detachment from August 2012 to July 2017. All patients' medical history and clinical features were recorded. The examinations included best corrected visual acuity (BCVA), intraocular pressure (IOP), fundus examination, and routine eye examinations. Posterior coats thickness (PCT) was determined by B-scan ultrasound, the CT was measured by enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) and clinical data were compiled and analyzed.RESULTS: After application of extensive exclusion criteria, 23 patients with PS remained (13 females, 10 males). The average age at presentation was 29.5±9.24 years old. Ocular pain and blurred vision were the two most common complained symptoms by patients. Anterior scleritis occurred in 12 patients, which was confirmed by ultrasound biomicroscopy (UBM) examination. Despite all patients displaying serous retinal detachment in their macula, no fluorescein leakage was observed in the macular area. Optic disc swelling was documented in 10 of the 23 eyes. From B-scan ultrasound examination, the PCT in creased with fluid in Tenon's capsule demonstrated as a typical T-sign. The average PCT was 2.51±0.81 mm in the PS-affected eyes and only 1.09±0.29 mm in the unaffected eye (P<0.0001). The subfoveal CT was 442.61 ±55.61 μm, which correlated with axis length (r=-0.65, P=0.001) and PCT (r=0.783, P<0.001). The BCVA and IOP did not correlate with either CT or PCT.CONCLUSION: PS with serous retinal detachment presented a variety of symptoms, such as pain, visual loss, and physical indicators. Typical T-sign detected by B-scan ultrasound is a useful confirmatory sign for PS diagnosis. Pathological increases in CT might be a potential predictive factor for inflammation.
文摘目的评价甲强龙联合地塞米松交替球周注射在玻璃体切割术治疗脉络膜脱离型视网膜脱离中的疗效。方法回顾性分析我科2012年1月至2013年12月收治的临床确诊为脉络膜脱离型视网膜脱离的患者共46例46眼。按糖皮质激素的给药途径,分为静脉组与球周组各23例23眼,均行玻璃体切除+硅油充填术,术后随访12个月以上。对比两组手术前后最佳矫正视力、眼压、术前糖皮质激素使用时间、不良反应发生率、视网膜脱离一次手术复位率、视网膜脱离复发率等。结果静脉组与球周组患者入院时眼压分别为(6.74±2.33)mm Hg(1 k Pa=7.5 mm Hg)和(6.96±1.88)mm Hg,使用糖皮质激素后术前眼压分别为(9.34±1.50)mm Hg和(9.43±1.08)mm Hg;最佳矫正视力入院时分别为2.07±0.14和2.23±0.16,出院时分别为2.02±0.17和2.03±0.14,两组组内比较差异均有统计学意义(均为P<0.05),而组间比较差异均无统计学意义(均为P>0.05)。术后12个月内静脉组与球周组一次性视网膜脱离复位例数分别为19例和21例、视网膜脱离复发例数分别为4例和2例,差异均无统计学意义(均为P>0.05);而两组在术前糖皮质激素使用时间,静脉组为(5.35±0.12)d、球周组为(4.04±0.38)d,差异有统计学意义(t=2.31,P=0.03);糖皮质激素使用不良反应,静脉组为6例、球周组为0例,差异有统计学意义(χ2=6.9,P=0.009)。结论甲强龙联合地塞米松交替球周注射是一种玻璃体切割术治疗脉络膜脱离型视网膜脱离的安全有效的方法。
