BACKGROUND Colorectal cancer is a common malignant tumor of the digestive tract.The relationship between sentinel polyps(rectal polyps with proximal colon cancer)and proximal colon cancer has received extensive attent...BACKGROUND Colorectal cancer is a common malignant tumor of the digestive tract.The relationship between sentinel polyps(rectal polyps with proximal colon cancer)and proximal colon cancer has received extensive attention in recent years.However,there is still no clear conclusion regarding the relationship.AIM To investigate the clinical characteristics of sentinel polyps and their correlation with proximal colon cancer.METHODS A retrospective analysis of 2587 patients with rectal polyps from January 2006 to December 2017 was performed.According to whether or not proximal colon cancer was diagnosed,the patients were divided into either a sentinel polyp group(192 patients)or a pure rectal polyp group(2395 patients).The endoscopic features,clinicopathological features,therapeutic effects,and short-term prognosis were analyzed and compared between the two groups.RESULTS The mean age of patients in the sentinel polyp group was generally higher than that of the pure rectal polyp group,and the positivity rates of anemia,stool occult blood,and tumor markers of the sentinel polyp group were also significantly higher than those in the rectal polyp group(χ^2=90.56,P<0.01;χ^2=70.30,P<0.01;χ^2=92.80,P<0.01).The majority of the patients in the sentinel polyp group had multiple polyps,large polyps,adenomatous polyps,or sessile polyps(χ^2=195.96,P<0.01;χ^2=460.46,P<0.01;χ^2=94.69,P<0.01;χ^2=48.01,P<0.01).Most of the proximal colon cancers were Duke’s A and B stages in the sentinel polyp group.In the pure rectal polyp group,2203 patients underwent endoscopic treatment,and all of the patients were cured and discharged.In the sentinel polyp group,65 patients underwent radical operation,and 61 patients received endoscopic submucosal dissection or endoscopic mucosal resection.Additionally,21 patients were lost to follow-up after 6-12 mo,and the loss rate was 10.94%.A total of 63.16%of patients experienced remission without tumor recurrence or metastasis,33.33%of patients experienced tumors regression or improved symptoms,and展开更多
目的回顾分析结直肠息肉术后再发的相关因素,为早期预防提供策略。方法对128例结直肠息肉术后患者,进行随访,并将随访资料及影响腺瘤再发相关因素进行Logistic回归分析,寻找息肉再发的高危因素。结果本组128例,5年内再发68例,再发率53....目的回顾分析结直肠息肉术后再发的相关因素,为早期预防提供策略。方法对128例结直肠息肉术后患者,进行随访,并将随访资料及影响腺瘤再发相关因素进行Logistic回归分析,寻找息肉再发的高危因素。结果本组128例,5年内再发68例,再发率53.13%。其中数目≥3个者46例,<3个者22例;息肉直径≥0.5 cm 45例,<0.5 cm 23例;单因素性别、年龄、生活习惯、息肉大小、数目等均为再发的重要因素。结论经多因素分析,男性、高龄、酗酒、吸烟、食用过多红肉、及息肉数目、大小等是结直肠息肉术后再发的高危因素;而素食、应用降糖药、非甾体类固醇激素等可降低其再发率。展开更多
文摘BACKGROUND Colorectal cancer is a common malignant tumor of the digestive tract.The relationship between sentinel polyps(rectal polyps with proximal colon cancer)and proximal colon cancer has received extensive attention in recent years.However,there is still no clear conclusion regarding the relationship.AIM To investigate the clinical characteristics of sentinel polyps and their correlation with proximal colon cancer.METHODS A retrospective analysis of 2587 patients with rectal polyps from January 2006 to December 2017 was performed.According to whether or not proximal colon cancer was diagnosed,the patients were divided into either a sentinel polyp group(192 patients)or a pure rectal polyp group(2395 patients).The endoscopic features,clinicopathological features,therapeutic effects,and short-term prognosis were analyzed and compared between the two groups.RESULTS The mean age of patients in the sentinel polyp group was generally higher than that of the pure rectal polyp group,and the positivity rates of anemia,stool occult blood,and tumor markers of the sentinel polyp group were also significantly higher than those in the rectal polyp group(χ^2=90.56,P<0.01;χ^2=70.30,P<0.01;χ^2=92.80,P<0.01).The majority of the patients in the sentinel polyp group had multiple polyps,large polyps,adenomatous polyps,or sessile polyps(χ^2=195.96,P<0.01;χ^2=460.46,P<0.01;χ^2=94.69,P<0.01;χ^2=48.01,P<0.01).Most of the proximal colon cancers were Duke’s A and B stages in the sentinel polyp group.In the pure rectal polyp group,2203 patients underwent endoscopic treatment,and all of the patients were cured and discharged.In the sentinel polyp group,65 patients underwent radical operation,and 61 patients received endoscopic submucosal dissection or endoscopic mucosal resection.Additionally,21 patients were lost to follow-up after 6-12 mo,and the loss rate was 10.94%.A total of 63.16%of patients experienced remission without tumor recurrence or metastasis,33.33%of patients experienced tumors regression or improved symptoms,and
文摘目的回顾分析结直肠息肉术后再发的相关因素,为早期预防提供策略。方法对128例结直肠息肉术后患者,进行随访,并将随访资料及影响腺瘤再发相关因素进行Logistic回归分析,寻找息肉再发的高危因素。结果本组128例,5年内再发68例,再发率53.13%。其中数目≥3个者46例,<3个者22例;息肉直径≥0.5 cm 45例,<0.5 cm 23例;单因素性别、年龄、生活习惯、息肉大小、数目等均为再发的重要因素。结论经多因素分析,男性、高龄、酗酒、吸烟、食用过多红肉、及息肉数目、大小等是结直肠息肉术后再发的高危因素;而素食、应用降糖药、非甾体类固醇激素等可降低其再发率。
