This paper presents the mean–variance(MV)model to solve power system reactive power dispatch problems with wind power integrated.The MV model considers the profit and risk simultaneously under the uncertain wind powe...This paper presents the mean–variance(MV)model to solve power system reactive power dispatch problems with wind power integrated.The MV model considers the profit and risk simultaneously under the uncertain wind power(speed)environment.To describe this uncertain environment,the Latin hypercube sampling with Cholesky decomposition simulation method is used to sample uncertain wind speeds.An improved optimization algorithm,group search optimizer with intraspecific competition and le´vy walk,is then used to optimize the MV model by introducing the risk tolerance parameter.The simulation is conducted based on the IEEE 30-bus power system,and the results demonstrate the effectiveness and validity of the proposed model and the optimization algorithm.展开更多
Hematopoietic stem cell transplantation(HSCT)becomes a standard form of cellular therapy for patients with malignant diseases.HSCT is the first-choice of immunotherapy,although HSCT can be associated with many complic...Hematopoietic stem cell transplantation(HSCT)becomes a standard form of cellular therapy for patients with malignant diseases.HSCT is the first-choice of immunotherapy,although HSCT can be associated with many complications such as graft-versus-host disease(GVHD)which is a major cause of morbidity and mortality after allogeneic HSCT.It has been shown that certain gut microbiota could exert protective and/or regenerative immunomodulatory effects by the production of short-chain fatty acids(SCFAs)such as butyrate in the experimental models of GVHD after allogeneic HSCT.Loss of gut commensal bacteria which can produce SCFAs may worsen dysbiosis,increasing the risk of GVHD.Expression of G-protein coupled receptors such as GPR41 seems to be upre-gulated in the presence of commensal bacteria,which might be associated with the biology of regulatory T cells(Tregs).Treg cells are a suppressive subset of CD4 positive T lymphocytes implicated in the prevention of GVHD after allogeneic HSCT.Here,we discuss the current findings of the relationship between the modification of gut microbiota and the GVHD-related immunity,which suggested that tactics with certain probiotics for the beneficial symbiosis in gut-immune axis might lead to the elevation of safety in the allogeneic HSCT.展开更多
基金The work is funded by Guangdong Innovative Research Team Program(No.201001N0104744201)National Key Basic Research and Development Program(973 Program,No.2012CB215100),ChinaThe first author thanks for the financial support from China Scholarship Council Program(No.201306150070).
文摘This paper presents the mean–variance(MV)model to solve power system reactive power dispatch problems with wind power integrated.The MV model considers the profit and risk simultaneously under the uncertain wind power(speed)environment.To describe this uncertain environment,the Latin hypercube sampling with Cholesky decomposition simulation method is used to sample uncertain wind speeds.An improved optimization algorithm,group search optimizer with intraspecific competition and le´vy walk,is then used to optimize the MV model by introducing the risk tolerance parameter.The simulation is conducted based on the IEEE 30-bus power system,and the results demonstrate the effectiveness and validity of the proposed model and the optimization algorithm.
文摘Hematopoietic stem cell transplantation(HSCT)becomes a standard form of cellular therapy for patients with malignant diseases.HSCT is the first-choice of immunotherapy,although HSCT can be associated with many complications such as graft-versus-host disease(GVHD)which is a major cause of morbidity and mortality after allogeneic HSCT.It has been shown that certain gut microbiota could exert protective and/or regenerative immunomodulatory effects by the production of short-chain fatty acids(SCFAs)such as butyrate in the experimental models of GVHD after allogeneic HSCT.Loss of gut commensal bacteria which can produce SCFAs may worsen dysbiosis,increasing the risk of GVHD.Expression of G-protein coupled receptors such as GPR41 seems to be upre-gulated in the presence of commensal bacteria,which might be associated with the biology of regulatory T cells(Tregs).Treg cells are a suppressive subset of CD4 positive T lymphocytes implicated in the prevention of GVHD after allogeneic HSCT.Here,we discuss the current findings of the relationship between the modification of gut microbiota and the GVHD-related immunity,which suggested that tactics with certain probiotics for the beneficial symbiosis in gut-immune axis might lead to the elevation of safety in the allogeneic HSCT.
