目的探讨剪切波弹性模量联合乳腺影像报告与数据系统(breast imaging reporting and data system,BI-RADS)分级对乳腺结节良恶性的诊断价值。方法对120个乳腺结节进行BI-RADS分级,并进行剪切波弹性成像检测,得到弹性模量平均值和标准差(...目的探讨剪切波弹性模量联合乳腺影像报告与数据系统(breast imaging reporting and data system,BI-RADS)分级对乳腺结节良恶性的诊断价值。方法对120个乳腺结节进行BI-RADS分级,并进行剪切波弹性成像检测,得到弹性模量平均值和标准差(Std),以弹性模量平均值、Std和BI-RADS分级作为自变量,建立回归方程;将回归方程计算得出的P值定义为结节恶性的预测概率值,找出最佳的诊断分界值。结果单纯BI-RADS分级的ROC曲线下面积为0.9330,诊断的灵敏性、特异性及准确度分别为0.95652、0.78378、0.85000,约登指数为0.74031。剪切波弹性模量联合BI-RADS分级的ROC曲线下面积为0.9900,对照病理诊断结果,取准确度与约登指数最大时结节恶性的预测概率值0.685为诊断分界点,诊断的灵敏性、特异性及准确度分别为0.91304、0.98649、0.95833,约登指数为0.89953。结论剪切波弹性模量与BI-RADS分级联合应用可显著提高乳腺结节诊断的特异性和准确率。展开更多
In this study, the 99mTc-MIBI myocardial bullseye display of 31 healthy persons and 34 patients with myocardial ischemia and 17 patients with myocardial infarction were analyzed quantitatively, and compared with the r...In this study, the 99mTc-MIBI myocardial bullseye display of 31 healthy persons and 34 patients with myocardial ischemia and 17 patients with myocardial infarction were analyzed quantitatively, and compared with the results of myocardial tomography analysis and qualitative bullseye analysis. The sensitivities of the three methods were 88.2%, 91.2 % and 94.1 % respectively (P>0.05),and the specificities were 93. 5%, 83, 9% and 83. 9% respectively (P<0.05).On the other hand, the quantitative analysis obviously outperformed the other two methods in the detection of ischemic segments of myocardium near infarction zone (P<0. 01). The quantitative analysis of 99mTc-MIBI myocardial bullseye (quantitative bullseye) was an objective, specific and sensitive method for diagnosis of coronary artery disease.展开更多
目的探讨超声造影(CEUS)定量分析在诊断移植肾肾小球性病变中的意义。方法回顾性分析44例移植肾患者的CEUS图像,用TCA定量分析软件拟合实质增强时的平均时间强度曲线(TIC),并输出定量参数。根据镜下是否存在移植肾小球性病变分为病变组...目的探讨超声造影(CEUS)定量分析在诊断移植肾肾小球性病变中的意义。方法回顾性分析44例移植肾患者的CEUS图像,用TCA定量分析软件拟合实质增强时的平均时间强度曲线(TIC),并输出定量参数。根据镜下是否存在移植肾小球性病变分为病变组及非病变组。比较校正后的峰值强度(PI)、曲线下面积(AUC)、上升段曲线下面积(AUC of wash-in)、下降段曲线下面积(AUC of wash-out)、相对AUC of wash-out及达峰时间(TTP)、平均通过时间(,MTT)等参数及病例资料。采用受试者工作曲线(ROC)评估各参数的诊断效能,并计算最佳临界值及该值的敏感性、特异性。结果排除取材不足的2例,余42例病例根据病理是否存在移植肾小球性病变分为病变组(n=22)及非病变组(n=20)。两组校正PI、校正AUC、校正AUC of wash-in及校正AUC of wash-out等参数之间的差异具有统计学意义(P<0.05)。上述参数的ROC曲线下面积分别为0.902、0.843、0.714及0.791,其诊断移植肾肾小球性病变的最佳临界值分别为≤0.237(敏感性90.9%,特异性83.0%)、≤0.188(敏感性63.6%,特异性100%)、≤0.148(敏感性77.3%,特异性75.0%)、≤0.179(敏感性59.1%,特异性90.0%)。结论校正PI、校正AUC、校正AUC of wash-in及校正AUC of wash-out等参数具有较高的诊断效能,其数值减低可提示移植肾肾小球性病变。展开更多
文摘目的探讨剪切波弹性模量联合乳腺影像报告与数据系统(breast imaging reporting and data system,BI-RADS)分级对乳腺结节良恶性的诊断价值。方法对120个乳腺结节进行BI-RADS分级,并进行剪切波弹性成像检测,得到弹性模量平均值和标准差(Std),以弹性模量平均值、Std和BI-RADS分级作为自变量,建立回归方程;将回归方程计算得出的P值定义为结节恶性的预测概率值,找出最佳的诊断分界值。结果单纯BI-RADS分级的ROC曲线下面积为0.9330,诊断的灵敏性、特异性及准确度分别为0.95652、0.78378、0.85000,约登指数为0.74031。剪切波弹性模量联合BI-RADS分级的ROC曲线下面积为0.9900,对照病理诊断结果,取准确度与约登指数最大时结节恶性的预测概率值0.685为诊断分界点,诊断的灵敏性、特异性及准确度分别为0.91304、0.98649、0.95833,约登指数为0.89953。结论剪切波弹性模量与BI-RADS分级联合应用可显著提高乳腺结节诊断的特异性和准确率。
文摘In this study, the 99mTc-MIBI myocardial bullseye display of 31 healthy persons and 34 patients with myocardial ischemia and 17 patients with myocardial infarction were analyzed quantitatively, and compared with the results of myocardial tomography analysis and qualitative bullseye analysis. The sensitivities of the three methods were 88.2%, 91.2 % and 94.1 % respectively (P>0.05),and the specificities were 93. 5%, 83, 9% and 83. 9% respectively (P<0.05).On the other hand, the quantitative analysis obviously outperformed the other two methods in the detection of ischemic segments of myocardium near infarction zone (P<0. 01). The quantitative analysis of 99mTc-MIBI myocardial bullseye (quantitative bullseye) was an objective, specific and sensitive method for diagnosis of coronary artery disease.
文摘目的探讨超声造影(CEUS)定量分析在诊断移植肾肾小球性病变中的意义。方法回顾性分析44例移植肾患者的CEUS图像,用TCA定量分析软件拟合实质增强时的平均时间强度曲线(TIC),并输出定量参数。根据镜下是否存在移植肾小球性病变分为病变组及非病变组。比较校正后的峰值强度(PI)、曲线下面积(AUC)、上升段曲线下面积(AUC of wash-in)、下降段曲线下面积(AUC of wash-out)、相对AUC of wash-out及达峰时间(TTP)、平均通过时间(,MTT)等参数及病例资料。采用受试者工作曲线(ROC)评估各参数的诊断效能,并计算最佳临界值及该值的敏感性、特异性。结果排除取材不足的2例,余42例病例根据病理是否存在移植肾小球性病变分为病变组(n=22)及非病变组(n=20)。两组校正PI、校正AUC、校正AUC of wash-in及校正AUC of wash-out等参数之间的差异具有统计学意义(P<0.05)。上述参数的ROC曲线下面积分别为0.902、0.843、0.714及0.791,其诊断移植肾肾小球性病变的最佳临界值分别为≤0.237(敏感性90.9%,特异性83.0%)、≤0.188(敏感性63.6%,特异性100%)、≤0.148(敏感性77.3%,特异性75.0%)、≤0.179(敏感性59.1%,特异性90.0%)。结论校正PI、校正AUC、校正AUC of wash-in及校正AUC of wash-out等参数具有较高的诊断效能,其数值减低可提示移植肾肾小球性病变。
