Aim: To explore the application effect of external diaphragm pacemaker combined with active respiratory circulation technology in pulmonary rehabilitation of perioperative lung cancer patients. Methods: A total of 98 ...Aim: To explore the application effect of external diaphragm pacemaker combined with active respiratory circulation technology in pulmonary rehabilitation of perioperative lung cancer patients. Methods: A total of 98 lung cancer patients admitted to our hospital from April 2020 to November 2021 were selected as the observation objects, and then divided into a control group and an observation group using the random number table method, with 49 cases in each group. The control group received routine admission guidance and active respiratory circulation training, while the observation group was supplemented with external diaphragm pacemaker on the basis of the control group. The intervention effect was evaluated by blood gas indicators, pulmonary function indicators, diaphragm function indicators, sputum comfort degree, and activity tolerance indicators before and after intervention. Results: Before intervention, there were no significant differences in blood gas analysis indicators, pulmonary function indicators, diaphragm function indicators, sputum comfort degree, and activity tolerance indicators between the two groups (P > 0.05). After intervention, the improvement degree of the above indicators in the observation group was higher than that in the control group (P < 0.05). Conclusions: The application of external diaphragm pacemaker combined with active respiratory circulation technology in pulmonary rehabilitation of perioperative lung cancer patients is significant, which can effectively improve the pulmonary function, blood gas function, and diaphragm function of lung cancer patients after surgery, and improve the activities of daily living and quality of life of patients.展开更多
目的:探讨微创肺表面活性物质给药(LISA)技术对新生儿呼吸窘迫综合征(NRDS)的治疗价值。方法:选取景德镇市妇幼保健院2019年5月-2022年8月收治的80例NRDS患儿,按随机数字表法分成传统组与LISA组,各40例。传统组采用气管插管-肺表面活性...目的:探讨微创肺表面活性物质给药(LISA)技术对新生儿呼吸窘迫综合征(NRDS)的治疗价值。方法:选取景德镇市妇幼保健院2019年5月-2022年8月收治的80例NRDS患儿,按随机数字表法分成传统组与LISA组,各40例。传统组采用气管插管-肺表面活性物质(PS)灌注-拔管(INSURE)治疗,LISA组采用LISA技术治疗。记录两组机械通气时间、吸氧时间、住院时间、PS用药剂量,比较两组给药前后的动脉血二氧化碳分压(PaCO_(2))、氧合指数(OI)、动脉血氧分压(PaO_(2))、动脉血氧饱和度(SaO_(2))、肺血管阻力(PVR)、血管外肺水含量(EVLW)、平均肺动脉压(mPAP)、右室每搏做功指数(RVSWI)及血清晚期氧化蛋白产物(AOPPs)、8-羟基脱氧鸟苷酸(8-OHdG)水平。记录患儿的不良反应与并发症情况。结果:LISA组机械通气及住院时间均短于传统组,PS用药剂量低于传统组,差异均有统计学意义(P<0.05)。两组给药后24 h PaCO_(2)均低于给药前,PaO_(2)、SaO_(2)、OI均高于给药前,且LISA组PaCO_(2)低于传统组,PaO_(2)、SaO_(2)、OI均高于传统组,差异均有统计学意义(P<0.05)。两组给药后24 h PVR、EVLW、mPAP均低于给药前,RVSWI高于给药前,且LISA组PVR、EVLW、mPAP均低于传统组,RVSWI高于传统组,差异均有统计学意义(P<0.05)。两组给药后24 h血清AOPPs、8-OHdG水平均低于给药前,且LISA组均较传统组低,差异均有统计学意义(P<0.05)。LISA组心动过缓、机械通气、再次给予PS占比分别为5.00%、12.50%、30.00%,低于传统组的20.00%、32.50%、52.50%,差异均有统计学意义(P<0.05)。结论:LISA技术能改善NRDS患儿的氧合功能与肺循环功能,降低心动过缓、机械通气、再次给予PS的发生率,并对血清AOPPs、8-OHdG水平有调控作用。展开更多
文摘Aim: To explore the application effect of external diaphragm pacemaker combined with active respiratory circulation technology in pulmonary rehabilitation of perioperative lung cancer patients. Methods: A total of 98 lung cancer patients admitted to our hospital from April 2020 to November 2021 were selected as the observation objects, and then divided into a control group and an observation group using the random number table method, with 49 cases in each group. The control group received routine admission guidance and active respiratory circulation training, while the observation group was supplemented with external diaphragm pacemaker on the basis of the control group. The intervention effect was evaluated by blood gas indicators, pulmonary function indicators, diaphragm function indicators, sputum comfort degree, and activity tolerance indicators before and after intervention. Results: Before intervention, there were no significant differences in blood gas analysis indicators, pulmonary function indicators, diaphragm function indicators, sputum comfort degree, and activity tolerance indicators between the two groups (P > 0.05). After intervention, the improvement degree of the above indicators in the observation group was higher than that in the control group (P < 0.05). Conclusions: The application of external diaphragm pacemaker combined with active respiratory circulation technology in pulmonary rehabilitation of perioperative lung cancer patients is significant, which can effectively improve the pulmonary function, blood gas function, and diaphragm function of lung cancer patients after surgery, and improve the activities of daily living and quality of life of patients.
文摘目的:探讨微创肺表面活性物质给药(LISA)技术对新生儿呼吸窘迫综合征(NRDS)的治疗价值。方法:选取景德镇市妇幼保健院2019年5月-2022年8月收治的80例NRDS患儿,按随机数字表法分成传统组与LISA组,各40例。传统组采用气管插管-肺表面活性物质(PS)灌注-拔管(INSURE)治疗,LISA组采用LISA技术治疗。记录两组机械通气时间、吸氧时间、住院时间、PS用药剂量,比较两组给药前后的动脉血二氧化碳分压(PaCO_(2))、氧合指数(OI)、动脉血氧分压(PaO_(2))、动脉血氧饱和度(SaO_(2))、肺血管阻力(PVR)、血管外肺水含量(EVLW)、平均肺动脉压(mPAP)、右室每搏做功指数(RVSWI)及血清晚期氧化蛋白产物(AOPPs)、8-羟基脱氧鸟苷酸(8-OHdG)水平。记录患儿的不良反应与并发症情况。结果:LISA组机械通气及住院时间均短于传统组,PS用药剂量低于传统组,差异均有统计学意义(P<0.05)。两组给药后24 h PaCO_(2)均低于给药前,PaO_(2)、SaO_(2)、OI均高于给药前,且LISA组PaCO_(2)低于传统组,PaO_(2)、SaO_(2)、OI均高于传统组,差异均有统计学意义(P<0.05)。两组给药后24 h PVR、EVLW、mPAP均低于给药前,RVSWI高于给药前,且LISA组PVR、EVLW、mPAP均低于传统组,RVSWI高于传统组,差异均有统计学意义(P<0.05)。两组给药后24 h血清AOPPs、8-OHdG水平均低于给药前,且LISA组均较传统组低,差异均有统计学意义(P<0.05)。LISA组心动过缓、机械通气、再次给予PS占比分别为5.00%、12.50%、30.00%,低于传统组的20.00%、32.50%、52.50%,差异均有统计学意义(P<0.05)。结论:LISA技术能改善NRDS患儿的氧合功能与肺循环功能,降低心动过缓、机械通气、再次给予PS的发生率,并对血清AOPPs、8-OHdG水平有调控作用。
