Ⅰ. INTRODUCTIONThe fractal is an irregular form with the self-similarity between the ordered and the fully disordered structure. Although there is a very complex conformation for the polypeptide chain of proteins by ...Ⅰ. INTRODUCTIONThe fractal is an irregular form with the self-similarity between the ordered and the fully disordered structure. Although there is a very complex conformation for the polypeptide chain of proteins by spontaneous folding and wrapping in the three-dimension space, several types of regular conformations, such as α-helix and β-sheet, have been formed. Therefore, it should be a research topic of interest to study the fractal and the fractal dimension of展开更多
Colorectal cancer is one of the common malignant tumors in our country. A large number of statistical data indicates that the rate of incidence and mortality of the disease in our country has been going up in recent y...Colorectal cancer is one of the common malignant tumors in our country. A large number of statistical data indicates that the rate of incidence and mortality of the disease in our country has been going up in recent years. Liver metastasis causes severe and fatal effect on patients who underwent radical resetsion due to colorectal cancer. Early forecast and diagnosis of liver metastasis is the key to improvie survival rate of colorectal cancer patients. This review focuses on the differential proteins which are associated with colorectal cancer genesis and liver metastasis in recent years, in order to offer the evidences for the early diagnosis and the prognosis.展开更多
The compact conformations of polymers are important because the native conformations of all bio-polymers with certain function are highly compact. The properties of mutil-contact bio-polymer chains were studied by Gau...The compact conformations of polymers are important because the native conformations of all bio-polymers with certain function are highly compact. The properties of mutil-contact bio-polymer chains were studied by Gaussian statistics of the random-flight chain. The theoretical expressions(were given, also), the calculations of probability distributions and correlation functions for different topologic cases were derived and made respectively. Comparison between single, double and triple contacts was also made. By means of setting the parameters, the results of the current calculations of the multiple contacts are just the same as those calculated by single, double or tripe contacts separately. It is a useful method to investigate native conformations of biopolymers. The probabilities of multi contacts and correlation functions between chain 's contacts were calculated for the Gaussian chains. Because the bond probability distributions are Gaussian 's distributions, the probability distributions of the separations of various points along the chains are always consecutive. All the contacts may break up into several groups, and each group consists of many contacts. Here we investigated the probability distribution from one group to three groups of contacts.展开更多
基金This work was supported by the Chinese Academy of Sciences 'Hundred Talent program' and National Natural Science Foundation of China (No.U1532151)to X.Z.and by Chinese national high magnetic field facilities,the Fundamental Research Funds for the Central Universities (No.WK2340000035) and National Natural Science Foundation of China (Nos.U1232210,11204306,and 11374278) to Q.Y.L.
基金Project supported by the National Natural Science Foundation of China.
文摘Ⅰ. INTRODUCTIONThe fractal is an irregular form with the self-similarity between the ordered and the fully disordered structure. Although there is a very complex conformation for the polypeptide chain of proteins by spontaneous folding and wrapping in the three-dimension space, several types of regular conformations, such as α-helix and β-sheet, have been formed. Therefore, it should be a research topic of interest to study the fractal and the fractal dimension of
文摘Colorectal cancer is one of the common malignant tumors in our country. A large number of statistical data indicates that the rate of incidence and mortality of the disease in our country has been going up in recent years. Liver metastasis causes severe and fatal effect on patients who underwent radical resetsion due to colorectal cancer. Early forecast and diagnosis of liver metastasis is the key to improvie survival rate of colorectal cancer patients. This review focuses on the differential proteins which are associated with colorectal cancer genesis and liver metastasis in recent years, in order to offer the evidences for the early diagnosis and the prognosis.
基金Supported by Zhejiang Provincial Natural Science Foundation of China( No. 10 10 0 2 ) and WenzhouCityScience Tech-nologyDevelopment Plan( No. S2 0 0 2 A0 14 ) and the Special Funds for Major State BasicResearchProjects( No.G19990 6 4 80 0 )
文摘The compact conformations of polymers are important because the native conformations of all bio-polymers with certain function are highly compact. The properties of mutil-contact bio-polymer chains were studied by Gaussian statistics of the random-flight chain. The theoretical expressions(were given, also), the calculations of probability distributions and correlation functions for different topologic cases were derived and made respectively. Comparison between single, double and triple contacts was also made. By means of setting the parameters, the results of the current calculations of the multiple contacts are just the same as those calculated by single, double or tripe contacts separately. It is a useful method to investigate native conformations of biopolymers. The probabilities of multi contacts and correlation functions between chain 's contacts were calculated for the Gaussian chains. Because the bond probability distributions are Gaussian 's distributions, the probability distributions of the separations of various points along the chains are always consecutive. All the contacts may break up into several groups, and each group consists of many contacts. Here we investigated the probability distribution from one group to three groups of contacts.
