目的观察宫颈环扎手术治疗中期妊娠宫颈机能不全的临床效果。方法回顾性分析2012年1月~2018年3月48例中期妊娠诊断为宫颈机能不全行宫颈环扎术的临床资料,观察患者术后情况[术后保胎时间、术后并发症(1周内阴道出血、胎膜早破、感染)]...目的观察宫颈环扎手术治疗中期妊娠宫颈机能不全的临床效果。方法回顾性分析2012年1月~2018年3月48例中期妊娠诊断为宫颈机能不全行宫颈环扎术的临床资料,观察患者术后情况[术后保胎时间、术后并发症(1周内阴道出血、胎膜早破、感染)]、妊娠结局(活产率、延长妊娠孕周、分娩孕周)及新生儿预后(出生体重及Apgar评分)。结果术后保胎时间(8.2±5.7)d。术后1周内阴道出血率33.3%(16/48)、胎膜早破率14.6%(7/48),感染率10.4%(5/48)。≥37孕周分娩22例,28~37孕周16例,<28孕周难免流产10例。围生儿存活率为86.8%(33/38),33例新生儿1 min Apgar评分7~10分,出生体重(2415±207)g,低出生体质量儿5例。结论对中期妊娠出现宫颈功能不全行宫颈环扎术可以有效改善患者的妊娠结局,根据患者自身情况个体化选择手术方式才能达到最佳疗效。展开更多
Background: Cervical insufficiency is one of the major causes of preterm birth among pregnant women that leads to severe mortality and morbidity issues among newborns. Prophylactic cervical cerclage is a surgical proc...Background: Cervical insufficiency is one of the major causes of preterm birth among pregnant women that leads to severe mortality and morbidity issues among newborns. Prophylactic cervical cerclage is a surgical procedure performed between 11 and 14 weeks of gestation upon diagnosis of cervix insufficiency among pregnant women. Aims & Objectives: In this study, we aimed to evaluate the effectiveness of prophylactic cervical cerclage in comparison to other interventions to treat cervical insufficiency among pregnant women using a meta-analysis approach. Methods: We searched the three databases (Coachrane Library, PubMed, and MEDLINE) that were used for articles related to research aims by using MeSH keywords. The timeline of research was set from January 2015 to January 2024. The methodological quality assessment of included studies was performed by the Risk of Bias in Non-randomized Studies—of Interventions (ROBINS-I). A recent meta-analysis was conducted by using Review Manager 5.4.0 software. Results: About 441 research articles were extracted from three electronic databases and only 125 articles were assessed for eligibility criteria. Finally, 8 studies were included in the analysis for a recent meta-analysis. Six out of eight included retrospective or pilot studies were graded as having a moderate risk of bias, and two studies had low risk on the basis of owning bias. About 1008 pregnant women with cervical insufficiency were analyzed in a recent meta-analysis. By pooled analysis, it was evaluated that significant difference found in prolongation of delivery weeks (Mean difference = 1.05;Cl: 0.81 to 1.29: p > 0.00001), number of deliveries > 37 weeks (OR = 0.59;Cl: 0.19 to 1.84: p > 0.006), and preterm birth (OR = 0.73;Cl: 0.42 to 1.28: p > 0.50) among pregnant women receiving prophylactic cervical cerclage as compared to other treatment strategies. Conclusion: Recent meta-analysis suggested the prophylactic cervical cerclage reduces the rates of preterm birth, abortion rates, number of deliveries > 37 wee展开更多
文摘目的观察宫颈环扎手术治疗中期妊娠宫颈机能不全的临床效果。方法回顾性分析2012年1月~2018年3月48例中期妊娠诊断为宫颈机能不全行宫颈环扎术的临床资料,观察患者术后情况[术后保胎时间、术后并发症(1周内阴道出血、胎膜早破、感染)]、妊娠结局(活产率、延长妊娠孕周、分娩孕周)及新生儿预后(出生体重及Apgar评分)。结果术后保胎时间(8.2±5.7)d。术后1周内阴道出血率33.3%(16/48)、胎膜早破率14.6%(7/48),感染率10.4%(5/48)。≥37孕周分娩22例,28~37孕周16例,<28孕周难免流产10例。围生儿存活率为86.8%(33/38),33例新生儿1 min Apgar评分7~10分,出生体重(2415±207)g,低出生体质量儿5例。结论对中期妊娠出现宫颈功能不全行宫颈环扎术可以有效改善患者的妊娠结局,根据患者自身情况个体化选择手术方式才能达到最佳疗效。
文摘Background: Cervical insufficiency is one of the major causes of preterm birth among pregnant women that leads to severe mortality and morbidity issues among newborns. Prophylactic cervical cerclage is a surgical procedure performed between 11 and 14 weeks of gestation upon diagnosis of cervix insufficiency among pregnant women. Aims & Objectives: In this study, we aimed to evaluate the effectiveness of prophylactic cervical cerclage in comparison to other interventions to treat cervical insufficiency among pregnant women using a meta-analysis approach. Methods: We searched the three databases (Coachrane Library, PubMed, and MEDLINE) that were used for articles related to research aims by using MeSH keywords. The timeline of research was set from January 2015 to January 2024. The methodological quality assessment of included studies was performed by the Risk of Bias in Non-randomized Studies—of Interventions (ROBINS-I). A recent meta-analysis was conducted by using Review Manager 5.4.0 software. Results: About 441 research articles were extracted from three electronic databases and only 125 articles were assessed for eligibility criteria. Finally, 8 studies were included in the analysis for a recent meta-analysis. Six out of eight included retrospective or pilot studies were graded as having a moderate risk of bias, and two studies had low risk on the basis of owning bias. About 1008 pregnant women with cervical insufficiency were analyzed in a recent meta-analysis. By pooled analysis, it was evaluated that significant difference found in prolongation of delivery weeks (Mean difference = 1.05;Cl: 0.81 to 1.29: p > 0.00001), number of deliveries > 37 weeks (OR = 0.59;Cl: 0.19 to 1.84: p > 0.006), and preterm birth (OR = 0.73;Cl: 0.42 to 1.28: p > 0.50) among pregnant women receiving prophylactic cervical cerclage as compared to other treatment strategies. Conclusion: Recent meta-analysis suggested the prophylactic cervical cerclage reduces the rates of preterm birth, abortion rates, number of deliveries > 37 wee
