Retailing is a dynamic business domain where commodities and goods are sold in small quantities directly to the customers.It deals with the end user customers of a supply-chain network and therefore has to accommodate...Retailing is a dynamic business domain where commodities and goods are sold in small quantities directly to the customers.It deals with the end user customers of a supply-chain network and therefore has to accommodate the needs and desires of a large group of customers over varied utilities.The volume and volatility of the business makes it one of the prospectivefields for analytical study and data modeling.This is also why customer segmentation drives a key role in multiple retail business decisions such as marketing budgeting,customer targeting,customized offers,value proposition etc.The segmentation could be on various aspects such as demographics,historic behavior or preferences based on the use cases.In this paper,historic retail transactional data is used to segment the custo-mers using K-Means clustering and the results are utilized to arrive at a transition matrix which is used to predict the cluster movements over the time period using Markov Model algorithm.This helps in calculating the futuristic value a segment or a customer brings to the business.Strategic marketing designs and budgeting can be implemented using these results.The study is specifically useful for large scale marketing in domains such as e-commerce,insurance or retailers to segment,profile and measure the customer lifecycle value over a short period of time.展开更多
The mammalian neocortex gives rise to perception and initiates voluntary motor responses.The cortical laminae are comprised of six distinct cellular layers of local circuit neurons and projection neurons.To explore mo...The mammalian neocortex gives rise to perception and initiates voluntary motor responses.The cortical laminae are comprised of six distinct cellular layers of local circuit neurons and projection neurons.To explore molecular identities of the distinct cortical projection neurons,discovery-orientated genomic approaches have been adopted.Microarray analysis of dissected cortical tissues has been applied to identify cortical layer markers.Early neuronal cells were sorted by FACS from GFP-labeled embryonic brains for gene expression profiling.Laser capture microdissection of retrograde-labeled pro-jection neurons,when coupled with optimal RNA amplification technology,has become a valuable strategy for neuronal isolation and gene expression analysis in differentiated neurons.RNA sequencing technology is promising not only for the determination of gene expression,but also for discovery of posttranscriptional modifications of the complex neural system.There is no doubt that advances in genomic studies are opening up novel research avenues for our understanding of the cortical neuronal functions.展开更多
文摘Retailing is a dynamic business domain where commodities and goods are sold in small quantities directly to the customers.It deals with the end user customers of a supply-chain network and therefore has to accommodate the needs and desires of a large group of customers over varied utilities.The volume and volatility of the business makes it one of the prospectivefields for analytical study and data modeling.This is also why customer segmentation drives a key role in multiple retail business decisions such as marketing budgeting,customer targeting,customized offers,value proposition etc.The segmentation could be on various aspects such as demographics,historic behavior or preferences based on the use cases.In this paper,historic retail transactional data is used to segment the custo-mers using K-Means clustering and the results are utilized to arrive at a transition matrix which is used to predict the cluster movements over the time period using Markov Model algorithm.This helps in calculating the futuristic value a segment or a customer brings to the business.Strategic marketing designs and budgeting can be implemented using these results.The study is specifically useful for large scale marketing in domains such as e-commerce,insurance or retailers to segment,profile and measure the customer lifecycle value over a short period of time.
基金supported by grants 30840034 and 30970924 from the National Natural Science Foundation of China.
文摘The mammalian neocortex gives rise to perception and initiates voluntary motor responses.The cortical laminae are comprised of six distinct cellular layers of local circuit neurons and projection neurons.To explore molecular identities of the distinct cortical projection neurons,discovery-orientated genomic approaches have been adopted.Microarray analysis of dissected cortical tissues has been applied to identify cortical layer markers.Early neuronal cells were sorted by FACS from GFP-labeled embryonic brains for gene expression profiling.Laser capture microdissection of retrograde-labeled pro-jection neurons,when coupled with optimal RNA amplification technology,has become a valuable strategy for neuronal isolation and gene expression analysis in differentiated neurons.RNA sequencing technology is promising not only for the determination of gene expression,but also for discovery of posttranscriptional modifications of the complex neural system.There is no doubt that advances in genomic studies are opening up novel research avenues for our understanding of the cortical neuronal functions.
