Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capill...Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of enzyme inhibitor screening. The period covers 2013 to 2017. Both the pre-capillary enzyme assays and in-capillary enzyme assays which include electrophoretically mediated microanalysis(EMMA) and immobilized enzyme microreactor(IMER) are summarized in this article.展开更多
Objective To investigate the risk factors associated with combined post-capillary and pre-capillary pulmonary hypertension(Cpc-PH)and the prognostic difference between isolated post-capillary pulmonary hypertension(Ip...Objective To investigate the risk factors associated with combined post-capillary and pre-capillary pulmonary hypertension(Cpc-PH)and the prognostic difference between isolated post-capillary pulmonary hypertension(Ipc-PH)and Cpc-PH in pulmonary hypertension due to left heart failure.Methods From October 2012 to November 2016,patients with pulmonary hypertension due to heart failure with preserved ejection fraction(PH-HFpEF)and pulmonary hypertension due to heart failure with reduced ejection fraction(PH-HFrEF)were prospectively enrolled from 11 centers all over the country.展开更多
基金financial support from the National Natural Science Foundation of China (Grant nos. 81573384 and 21375101)
文摘Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of enzyme inhibitor screening. The period covers 2013 to 2017. Both the pre-capillary enzyme assays and in-capillary enzyme assays which include electrophoretically mediated microanalysis(EMMA) and immobilized enzyme microreactor(IMER) are summarized in this article.
文摘Objective To investigate the risk factors associated with combined post-capillary and pre-capillary pulmonary hypertension(Cpc-PH)and the prognostic difference between isolated post-capillary pulmonary hypertension(Ipc-PH)and Cpc-PH in pulmonary hypertension due to left heart failure.Methods From October 2012 to November 2016,patients with pulmonary hypertension due to heart failure with preserved ejection fraction(PH-HFpEF)and pulmonary hypertension due to heart failure with reduced ejection fraction(PH-HFrEF)were prospectively enrolled from 11 centers all over the country.