Polymer complex is a polymer association of different polymers with good miscibility resulting from the relatively strong intermolecular interactions or stereo match effect between polymer chains. Polymer complexes ha...Polymer complex is a polymer association of different polymers with good miscibility resulting from the relatively strong intermolecular interactions or stereo match effect between polymer chains. Polymer complexes have been utilized in various fields, such as food, biomedical, cosmetic, and pharmacy. Fiber is one of the most important material forms, and shaping polymer complex into fiber will further extend its applications. This review briefly introduces the fundamentals of polymer complex, and then demonstrates the main approaches to produce polymer complex fibers(PCFs). Followed by, the modification of fibers with polymer complexes is presented. Finally, the applications of PCFs and the polymer complex modified fibers are provided, and the prospect of polymer complexation for fibers is discussed properly.展开更多
The liquid-liquid phase separation of biopolymers in living cells contains multiple interactions and occurs in a dynamic environment.Resolving the regulation mechanism is still a challenge.In this work,we designed a s...The liquid-liquid phase separation of biopolymers in living cells contains multiple interactions and occurs in a dynamic environment.Resolving the regulation mechanism is still a challenge.In this work,we designed a series of peptides(XXLY)_(6)SSSGSS and studied their complexation and coacervation behavior with single-stranded oligonucleotides.The“X”and“Y”are varied to combine known amounts of charged and non-charged amino acids,together with the introduction of secondary structures and pH responsiveness.Results show that the electrostatic interaction,which is described as charge density,controls both the strength of complexation and the degree of chain relaxation,and thus determines the growth and size of the coacervates.The hydrophobic interaction is prominent when the charges are neutralized.Interestingly,the secondary structures of peptides exhibit profound effect on the morphology of the phases,such as solid phase to liquid phase transition.Our study gains insight into the phase separation under physiological conditions.It is also helpful to create coacervates with desirable structures and functions.展开更多
基金supported by the Science and Technology Commission of Shanghai Municipality(Grant No.16JC1400700)
文摘Polymer complex is a polymer association of different polymers with good miscibility resulting from the relatively strong intermolecular interactions or stereo match effect between polymer chains. Polymer complexes have been utilized in various fields, such as food, biomedical, cosmetic, and pharmacy. Fiber is one of the most important material forms, and shaping polymer complex into fiber will further extend its applications. This review briefly introduces the fundamentals of polymer complex, and then demonstrates the main approaches to produce polymer complex fibers(PCFs). Followed by, the modification of fibers with polymer complexes is presented. Finally, the applications of PCFs and the polymer complex modified fibers are provided, and the prospect of polymer complexation for fibers is discussed properly.
基金supported by the National Natural Science Foundation of China(No.21973002).
文摘The liquid-liquid phase separation of biopolymers in living cells contains multiple interactions and occurs in a dynamic environment.Resolving the regulation mechanism is still a challenge.In this work,we designed a series of peptides(XXLY)_(6)SSSGSS and studied their complexation and coacervation behavior with single-stranded oligonucleotides.The“X”and“Y”are varied to combine known amounts of charged and non-charged amino acids,together with the introduction of secondary structures and pH responsiveness.Results show that the electrostatic interaction,which is described as charge density,controls both the strength of complexation and the degree of chain relaxation,and thus determines the growth and size of the coacervates.The hydrophobic interaction is prominent when the charges are neutralized.Interestingly,the secondary structures of peptides exhibit profound effect on the morphology of the phases,such as solid phase to liquid phase transition.Our study gains insight into the phase separation under physiological conditions.It is also helpful to create coacervates with desirable structures and functions.
