目的通过对我院医学检验科生化专业组2012~2017年连续6年参加美国病理家协会(College of American Pathologists,CAP)组织的常规化学能力验证计划的成绩进行统计分析,全面评价检测性能,发现存在的问题并对其进行改进,为质量控制提供依据...目的通过对我院医学检验科生化专业组2012~2017年连续6年参加美国病理家协会(College of American Pathologists,CAP)组织的常规化学能力验证计划的成绩进行统计分析,全面评价检测性能,发现存在的问题并对其进行改进,为质量控制提供依据,提高检测结果的准确性。方法评估首都医科大学附属北京世纪坛医院医学检验科生化专业组2012~2017年参加CAP常规化学的PT结果,对失控项目的原因进行统计分析。结果 2013年项次合格率最高,为100%;2014年项次合格率最低,为87. 5%;共有19个检测项目在2012~2017年成绩全部为100分,13个项目出现过成绩不合格;导致项目不合格的所有原因中,PT样本问题最突出,占68. 75%;其次是检测系统问题和分组不恰当,均为9. 38%,随机误差占比6. 25%;技术问题和书写错误占3. 13%。结论 CAP的能力验证活动可以用于对实验室的检测能力进行评估,对2012~2017年参加CAP的常规化学能力验证成绩进行总结,分析探讨不合格原因并采取相应纠正措施,可以进一步提高实验室结果的可靠性、准确性及可比性,以保证实验室对患者的服务质量。展开更多
目的通过参加美国病理家协会(College of American Pathologists,CAP)的能力比对检验(proficiency testing,PT),评价骨髓细胞形态学检验水平。方法将收到的PT样本按照临床常规样本对待,在规定日期内通过网络将上述结果反馈给CAP,并根据...目的通过参加美国病理家协会(College of American Pathologists,CAP)的能力比对检验(proficiency testing,PT),评价骨髓细胞形态学检验水平。方法将收到的PT样本按照临床常规样本对待,在规定日期内通过网络将上述结果反馈给CAP,并根据回报结果进行自我评估。结果两次PT中骨髓细胞分类计数13项中有1项自评未通过,每次PT有5个细胞辨识参加测评,共有3个细胞辨识自评未通过。结论通过CAP认可及参加能力比对检验,规范了骨髓细胞形态学检测流程,并通过CA P学习罕见骨髓形态病例,拓展了实验室检测能力。展开更多
目的汇总我室参加美国病理家学会(College of American Pathologists,CAP)自身抗体项目的能力比对结果,发现问题并进行整改,提高专业组对自身抗体项目的检测能力和结果准确性。方法回顾分析2012年至2019年参加CAP自身抗体项目情况。按...目的汇总我室参加美国病理家学会(College of American Pathologists,CAP)自身抗体项目的能力比对结果,发现问题并进行整改,提高专业组对自身抗体项目的检测能力和结果准确性。方法回顾分析2012年至2019年参加CAP自身抗体项目情况。按照临床常规样本对待收到的PT样本,在规定日期内通过网络将上述结果反馈给CAP。根据CAP反馈结果,专业组对未评分项目开展自我评估,对不合格项目进行原因分析。结果2012年至2019年我室参加的CAP自身抗体能力比对共计17项、402项次,8年总合格率为98%。13项参评项目的8年总符合率为100%,4个参评项目总符合率未达到100%,项目以及总符合率分别是抗平滑肌抗体(ASMA)90%、抗组蛋白抗体(AHT)92%、抗SSA抗体(SSA)94%、抗胃壁细胞抗体(APC)96%。结论实验室对于自身抗体检测能力较好,对于不合格项目进行原因分析并持续改进,保证实验室检测准确性。展开更多
Objective： To compare the numbers of positive and total lymph nodes and prognosis in gastric cancer patients whose perigastric lymph node retrieval was performed by surgeons and pathologists. Methods： We conducted a...Objective： To compare the numbers of positive and total lymph nodes and prognosis in gastric cancer patients whose perigastric lymph node retrieval was performed by surgeons and pathologists. Methods： We conducted a retrospective analysis of clinical and follow-up data from 1,056 patients who underwent gastric cancer D2 radical lymph node resection between January 2008 and December 2010 in the Gastrointestinal Surgery Department of Yantai Yuhuangding Hospital. The follow-up ended in December 2015. Patients were divided into two groups according to the specialty of physicians who performed the postoperative perigastric lymph node retrieval： the surgeon group （475 cases） and the pathologist group （581 cases）. The numbers of positive and total perigastric lymph nodes and the 3- and 5-year survival were compared between gastric cancer patients in the two groups overall and stratified by TNM stage （AJCC 7th Edition）. Results： Overall, the numbers of positive and total lymph nodes were significantly higher in the surgeon group than in the pathologist group （6.53±4.07 vs. 4.09±3.70, P=0.021; 29.64±11.50 vs. 20.71±8.56, P〈0.001）. Further analysis showed that the total number of lymph nodes in stage Ⅰ patients （19.40±9.62 vs. 15.45±8.59, P=0.011） and the numbers of positive and total lymph nodes in stage Ⅱ（1.38±1.08 vs. 0.87±1.55, P=0.031; 25.35±10.80 vs. 16.75±8.56, P〈0.001） and stage Ⅲ patients （8.11±6.91 vs. 6.66±5.12, P=0.026; 32.34±12.55 vs. 25.45±8.31, P〈0.001） were significantly higher in the surgeon group than in the pathologist group. The survival analysis showed that the 3- and 5-year survival of stage Ⅱ and Ⅲ patients was significantly higher in the surgeon group than in the pathologist group （82.0% vs. 73.1%, 69.5% vs. 61.2%, P=0.038; 49.2% vs. 38.9%, 36.3% vs. 28.0%; P=0.045）. Conclusions： Compared with retrieval performed by pathologists, postoperative perigastrie lymph node retrieval performed by surgeons was associated with significant展开更多
文摘目的通过参加美国病理家协会(College of American Pathologists,CAP)的能力比对检验(proficiency testing,PT),评价骨髓细胞形态学检验水平。方法将收到的PT样本按照临床常规样本对待,在规定日期内通过网络将上述结果反馈给CAP,并根据回报结果进行自我评估。结果两次PT中骨髓细胞分类计数13项中有1项自评未通过,每次PT有5个细胞辨识参加测评,共有3个细胞辨识自评未通过。结论通过CAP认可及参加能力比对检验,规范了骨髓细胞形态学检测流程,并通过CA P学习罕见骨髓形态病例,拓展了实验室检测能力。
文摘目的汇总我室参加美国病理家学会(College of American Pathologists,CAP)自身抗体项目的能力比对结果,发现问题并进行整改,提高专业组对自身抗体项目的检测能力和结果准确性。方法回顾分析2012年至2019年参加CAP自身抗体项目情况。按照临床常规样本对待收到的PT样本,在规定日期内通过网络将上述结果反馈给CAP。根据CAP反馈结果,专业组对未评分项目开展自我评估,对不合格项目进行原因分析。结果2012年至2019年我室参加的CAP自身抗体能力比对共计17项、402项次,8年总合格率为98%。13项参评项目的8年总符合率为100%,4个参评项目总符合率未达到100%,项目以及总符合率分别是抗平滑肌抗体(ASMA)90%、抗组蛋白抗体(AHT)92%、抗SSA抗体(SSA)94%、抗胃壁细胞抗体(APC)96%。结论实验室对于自身抗体检测能力较好,对于不合格项目进行原因分析并持续改进,保证实验室检测准确性。
文摘Objective： To compare the numbers of positive and total lymph nodes and prognosis in gastric cancer patients whose perigastric lymph node retrieval was performed by surgeons and pathologists. Methods： We conducted a retrospective analysis of clinical and follow-up data from 1,056 patients who underwent gastric cancer D2 radical lymph node resection between January 2008 and December 2010 in the Gastrointestinal Surgery Department of Yantai Yuhuangding Hospital. The follow-up ended in December 2015. Patients were divided into two groups according to the specialty of physicians who performed the postoperative perigastric lymph node retrieval： the surgeon group （475 cases） and the pathologist group （581 cases）. The numbers of positive and total perigastric lymph nodes and the 3- and 5-year survival were compared between gastric cancer patients in the two groups overall and stratified by TNM stage （AJCC 7th Edition）. Results： Overall, the numbers of positive and total lymph nodes were significantly higher in the surgeon group than in the pathologist group （6.53±4.07 vs. 4.09±3.70, P=0.021; 29.64±11.50 vs. 20.71±8.56, P〈0.001）. Further analysis showed that the total number of lymph nodes in stage Ⅰ patients （19.40±9.62 vs. 15.45±8.59, P=0.011） and the numbers of positive and total lymph nodes in stage Ⅱ（1.38±1.08 vs. 0.87±1.55, P=0.031; 25.35±10.80 vs. 16.75±8.56, P〈0.001） and stage Ⅲ patients （8.11±6.91 vs. 6.66±5.12, P=0.026; 32.34±12.55 vs. 25.45±8.31, P〈0.001） were significantly higher in the surgeon group than in the pathologist group. The survival analysis showed that the 3- and 5-year survival of stage Ⅱ and Ⅲ patients was significantly higher in the surgeon group than in the pathologist group （82.0% vs. 73.1%, 69.5% vs. 61.2%, P=0.038; 49.2% vs. 38.9%, 36.3% vs. 28.0%; P=0.045）. Conclusions： Compared with retrieval performed by pathologists, postoperative perigastrie lymph node retrieval performed by surgeons was associated with significant
