Background:Medicinal herbs have always been closely associated with human beings,and no one deny their medicinal effects and uses.There are over 7,500 plant species in the rich flora of Iran.This study,intends to inve...Background:Medicinal herbs have always been closely associated with human beings,and no one deny their medicinal effects and uses.There are over 7,500 plant species in the rich flora of Iran.This study,intends to investigate the anti-bacterial properties of three different plant species from Iranian flora,including Echinops persicus,Cardamine uliginosa,and Vaccaria oxyodontha Boiss.Materials and methods:This cross-sectional study was performed after confirmation and identification of collected plants.The plants were dried in the shade for extraction.Then the methanol extract of these plants was extracted by the classical extraction method.The plants’antimicrobial effects of the plants were evaluated by agar disk diffusion,minimum inhibitory concentration,and minimum bactericidal concentration.The mentioned plants’anti-bacterial activity was compared with the antibiotic discs of gentamicin(10 mg)and vancomycin(30 mg).SPSS software v20 was used for data analysis of Kruskal-Wallis and Dunn’s tests(P<0.05).Results:The lowest minimum inhibitory concentration obtained from the methanol extract of Cardamine uliginosa on standard strains of Staphylococcus aureus and Escherichia coli at 15.62 mg/mL for methanol extracts of Echinops persicus and Vaccaria oxyodontha Boiss on S.aureus and E.coli at 31.25 mg/mL and 125 mg/mL,respectively.The highest diameter of inhibition zone caused by methanol extract of Cardamine uiliginosa was against S.aureus and E.coli with an inhibition zone of 23.9±0.29 mm and 20.4±0.43 mm,respectively.Compared with the antibiotics gentamicin and vancomycin,the Cardamine uliginosa showed a stronger inhibitory effect(P<0.05).Conclusion:Echinops persicus,Cardamine uliginosa,and Vaccaria oxyodontha Boiss have anti-bacterial properties.The anti-bacterial property of Cardamine uilignosa is higher than the other two herbal medicine.展开更多
文摘Background:Medicinal herbs have always been closely associated with human beings,and no one deny their medicinal effects and uses.There are over 7,500 plant species in the rich flora of Iran.This study,intends to investigate the anti-bacterial properties of three different plant species from Iranian flora,including Echinops persicus,Cardamine uliginosa,and Vaccaria oxyodontha Boiss.Materials and methods:This cross-sectional study was performed after confirmation and identification of collected plants.The plants were dried in the shade for extraction.Then the methanol extract of these plants was extracted by the classical extraction method.The plants’antimicrobial effects of the plants were evaluated by agar disk diffusion,minimum inhibitory concentration,and minimum bactericidal concentration.The mentioned plants’anti-bacterial activity was compared with the antibiotic discs of gentamicin(10 mg)and vancomycin(30 mg).SPSS software v20 was used for data analysis of Kruskal-Wallis and Dunn’s tests(P<0.05).Results:The lowest minimum inhibitory concentration obtained from the methanol extract of Cardamine uliginosa on standard strains of Staphylococcus aureus and Escherichia coli at 15.62 mg/mL for methanol extracts of Echinops persicus and Vaccaria oxyodontha Boiss on S.aureus and E.coli at 31.25 mg/mL and 125 mg/mL,respectively.The highest diameter of inhibition zone caused by methanol extract of Cardamine uiliginosa was against S.aureus and E.coli with an inhibition zone of 23.9±0.29 mm and 20.4±0.43 mm,respectively.Compared with the antibiotics gentamicin and vancomycin,the Cardamine uliginosa showed a stronger inhibitory effect(P<0.05).Conclusion:Echinops persicus,Cardamine uliginosa,and Vaccaria oxyodontha Boiss have anti-bacterial properties.The anti-bacterial property of Cardamine uilignosa is higher than the other two herbal medicine.
