Objective:To examine the effect of moxibustion on the wound healing process and its mechanism using a rat wound model.Methods:Sixty male Sprague-Dawley rats were randomly divided into a sham-treated group(n=30,wound s...Objective:To examine the effect of moxibustion on the wound healing process and its mechanism using a rat wound model.Methods:Sixty male Sprague-Dawley rats were randomly divided into a sham-treated group(n=30,wound surgery only)and a moxibustion group(n=30,wound treated with moxibustion).Circular fullthick ness skin wounds were produced in rats.Moxibustion was applied to the edge of wound and was continued on alternating days till 14 days after surgery,followed by measurement of wound size.Expression of collagens,prolyl-4-hydroxylase(P4H)and transtorming growth factor-β(TGF-β)were evaluated by histochemical study and real-time polymerase chain reaction.Results:The size of the wound lesion was significantly reduced in rats treated with moxibustion as compared to that in sham-treated rats at 4-10 days after wounding(P<0.01).Moxibusti on stimulated mRNA expressi on of collage ns at 4 days(P<0.01),but not at 7 days,accompa nied by enhanced proliferation of P4H-positive fibroblasts.Of importanee,expression of TGF-β in tissue from the wound lesio n treated with moxibusti on was sign ifica ntly in creased as compared to that in sham-treated rats at 4 days(P<0.01 or P<0.05),but not at 7 days.Conclusions:The treatment with moxibustion promoted the wound healing process in the early phase through proliferation of fibroblasts and rapid formation of granulation,possibly mediated by induction of TGF-β which is a key molecule in the physiological process of wound healing.Moxibustion can be expected to be effective as complementary treatment for intractable ulcers.展开更多
Inter-regional and transnational grid interconnection is necessary for energy development. Xinjiang, which is rich in renewable energy resources, is adjacent to countries in Central Asia and has great potential for in...Inter-regional and transnational grid interconnection is necessary for energy development. Xinjiang, which is rich in renewable energy resources, is adjacent to countries in Central Asia and has great potential for interconnection with its neighbors. This paper outlines China's relevant policies for transnational power interconnection, and introduces the energy structure, load demand endowments, and power supply status of Xinjiang, Pakistan, and five Central Asian countries. Further, it analyzes the advantages of the multinational power interconnection from the aspects of power supply and load complementation. Finally, from the perspective of technical support and practical basis, the feasibility of interconnection between Xinjiang, Pakistan, and five Central Asian countries have been analyzed. This paper provides a theoretical basis for promoting and implementing China's "Belt and Road" power transnational interconnected development strategy.展开更多
文摘Objective:To examine the effect of moxibustion on the wound healing process and its mechanism using a rat wound model.Methods:Sixty male Sprague-Dawley rats were randomly divided into a sham-treated group(n=30,wound surgery only)and a moxibustion group(n=30,wound treated with moxibustion).Circular fullthick ness skin wounds were produced in rats.Moxibustion was applied to the edge of wound and was continued on alternating days till 14 days after surgery,followed by measurement of wound size.Expression of collagens,prolyl-4-hydroxylase(P4H)and transtorming growth factor-β(TGF-β)were evaluated by histochemical study and real-time polymerase chain reaction.Results:The size of the wound lesion was significantly reduced in rats treated with moxibustion as compared to that in sham-treated rats at 4-10 days after wounding(P<0.01).Moxibusti on stimulated mRNA expressi on of collage ns at 4 days(P<0.01),but not at 7 days,accompa nied by enhanced proliferation of P4H-positive fibroblasts.Of importanee,expression of TGF-β in tissue from the wound lesio n treated with moxibusti on was sign ifica ntly in creased as compared to that in sham-treated rats at 4 days(P<0.01 or P<0.05),but not at 7 days.Conclusions:The treatment with moxibustion promoted the wound healing process in the early phase through proliferation of fibroblasts and rapid formation of granulation,possibly mediated by induction of TGF-β which is a key molecule in the physiological process of wound healing.Moxibustion can be expected to be effective as complementary treatment for intractable ulcers.
基金Supported by the State Grid Scientific and Technological Project (Title: Research on the Development and Integration Mode of Renewable Energy in Xinjiang Power Grid under the Background of Multinational Interconnection, NY71-17-008)
文摘Inter-regional and transnational grid interconnection is necessary for energy development. Xinjiang, which is rich in renewable energy resources, is adjacent to countries in Central Asia and has great potential for interconnection with its neighbors. This paper outlines China's relevant policies for transnational power interconnection, and introduces the energy structure, load demand endowments, and power supply status of Xinjiang, Pakistan, and five Central Asian countries. Further, it analyzes the advantages of the multinational power interconnection from the aspects of power supply and load complementation. Finally, from the perspective of technical support and practical basis, the feasibility of interconnection between Xinjiang, Pakistan, and five Central Asian countries have been analyzed. This paper provides a theoretical basis for promoting and implementing China's "Belt and Road" power transnational interconnected development strategy.
