Genetic analysis of three H1N2 viruses indicated that only HA genes of H1N2 viruses were similar to that of A/Guangdong/6/91(H1N1) virus (PR8-like strain), while the other seven genes of them were similar to those of ...Genetic analysis of three H1N2 viruses indicated that only HA genes of H1N2 viruses were similar to that of A/Guangdong/6/91(H1N1) virus (PR8-like strain), while the other seven genes of them were similar to those of H3N2 virus circulating in man in 1995. Therefore, it could be considered that the H1N2 viruses were derived from reassortment between PR8-like strain and H3N2 virus circulating in man in 1995. However, the genomes of H1N2 viruses were very similar to each other. So the H1N2 viruses isolated in 1998 were not derived from new reassortment between PR8-like strain and H3N2 virus circulating in man in 1998, but derived from the evolution of H1N2 virus found in 1995.展开更多
Dear Editor,Influenza A viruses cause pandemics at an interval of approximately 10-40 years,and pigs are regarded as a＂mixing vessel＂because they are easily infected with avian and human influenza viruses（Ito et al...Dear Editor,Influenza A viruses cause pandemics at an interval of approximately 10-40 years,and pigs are regarded as a＂mixing vessel＂because they are easily infected with avian and human influenza viruses（Ito et al.,1998）.According to previous studies,H3N2,H1N2,and H1N1 subtypes o（swine influenza viruses have been detected in Korean pigs （Pascua et al., 2013; Kim et al., 2014; Song et al., 2007）. Moreover, a novel H3N2 influenza virus containing the matrix （34） gene from a 2009 pandemic influenza virus was detected in Korean pigs in 2013 （Pascua et al., 2013）, an H1N2 influenza virus con- taining the internal genes from a 2009 pandemic influ- enza virus was found in Korean pigs in 2014 （Kim et al., 2014）, and an H1N1 influenza virus containing all genes from the classical swine influenza viruses was isolated from Korean pigs in 2007 （Song et al., 2007）.展开更多
目的:分析大连市2009年-2010年流感病毒核酸监测结果,了解甲型H1N1流感病毒和季节性流感病毒的流行规律,探讨甲型H1N1流感与季节性流感的相互关系。方法:对大连市2家国家级流感监测哨点医院的流感样病人咽拭子标本采用Real-tim e RT-PC...目的:分析大连市2009年-2010年流感病毒核酸监测结果,了解甲型H1N1流感病毒和季节性流感病毒的流行规律,探讨甲型H1N1流感与季节性流感的相互关系。方法:对大连市2家国家级流感监测哨点医院的流感样病人咽拭子标本采用Real-tim e RT-PCR方法进行检测,对数据采用描述性流行病学方法进行分析。结果:共检测1867份标本,各型流感病毒核酸检测总阳性率为19.82%,各年龄组阳性率差别有统计学意义(P<0.05);从2009年7月-2010年6月期间,共出现了2次流感流行高峰,第1个峰是在2009年10月-2009年11月,由甲型H1N1流感病毒引起,第2个峰是在2010年2月,由乙型流感病毒引起。结论:大连市2009年-2010年流感的主要发病群体为中小学生和青壮年人群;季节性流感的流行优势株为乙型流感病毒,甲型H1N1流感病毒的出现未引起季节性流感的流行特征的变化。展开更多
文摘Genetic analysis of three H1N2 viruses indicated that only HA genes of H1N2 viruses were similar to that of A/Guangdong/6/91(H1N1) virus (PR8-like strain), while the other seven genes of them were similar to those of H3N2 virus circulating in man in 1995. Therefore, it could be considered that the H1N2 viruses were derived from reassortment between PR8-like strain and H3N2 virus circulating in man in 1995. However, the genomes of H1N2 viruses were very similar to each other. So the H1N2 viruses isolated in 1998 were not derived from new reassortment between PR8-like strain and H3N2 virus circulating in man in 1998, but derived from the evolution of H1N2 virus found in 1995.
基金in part funded by a 2015 research fund from Chungnam National University
文摘Dear Editor,Influenza A viruses cause pandemics at an interval of approximately 10-40 years,and pigs are regarded as a＂mixing vessel＂because they are easily infected with avian and human influenza viruses（Ito et al.,1998）.According to previous studies,H3N2,H1N2,and H1N1 subtypes o（swine influenza viruses have been detected in Korean pigs （Pascua et al., 2013; Kim et al., 2014; Song et al., 2007）. Moreover, a novel H3N2 influenza virus containing the matrix （34） gene from a 2009 pandemic influenza virus was detected in Korean pigs in 2013 （Pascua et al., 2013）, an H1N2 influenza virus con- taining the internal genes from a 2009 pandemic influ- enza virus was found in Korean pigs in 2014 （Kim et al., 2014）, and an H1N1 influenza virus containing all genes from the classical swine influenza viruses was isolated from Korean pigs in 2007 （Song et al., 2007）.
文摘目的:分析大连市2009年-2010年流感病毒核酸监测结果,了解甲型H1N1流感病毒和季节性流感病毒的流行规律,探讨甲型H1N1流感与季节性流感的相互关系。方法:对大连市2家国家级流感监测哨点医院的流感样病人咽拭子标本采用Real-tim e RT-PCR方法进行检测,对数据采用描述性流行病学方法进行分析。结果:共检测1867份标本,各型流感病毒核酸检测总阳性率为19.82%,各年龄组阳性率差别有统计学意义(P<0.05);从2009年7月-2010年6月期间,共出现了2次流感流行高峰,第1个峰是在2009年10月-2009年11月,由甲型H1N1流感病毒引起,第2个峰是在2010年2月,由乙型流感病毒引起。结论:大连市2009年-2010年流感的主要发病群体为中小学生和青壮年人群;季节性流感的流行优势株为乙型流感病毒,甲型H1N1流感病毒的出现未引起季节性流感的流行特征的变化。
