A novel colorimetric chemosensor PBIOSi has been designed and synthesized. The addition of F to a THF solution of PBIOSi resulted in an obvious color change （from red to green） in a short time because of the specifi...A novel colorimetric chemosensor PBIOSi has been designed and synthesized. The addition of F to a THF solution of PBIOSi resulted in an obvious color change （from red to green） in a short time because of the specific cleavage of Si-O bond in PBIOSi by F-. It was interesting that PBIOSi showed excellent selectivity for F detection over other halides. The UV-Vis absorption and fluorescence were changed linearly with the concentration ofF over the range of 0- 10 μmol/L.展开更多
We consider a face-to-face videoconferencing system that uses a Kinect camera at each end of the link for 3D modeling and an ordinary2 D display for output. The Kinect camera allows a 3D model of each participant to b...We consider a face-to-face videoconferencing system that uses a Kinect camera at each end of the link for 3D modeling and an ordinary2 D display for output. The Kinect camera allows a 3D model of each participant to be transmitted;the(assumed static) background is sent separately.Furthermore, the Kinect tracks the receiver's head,allowing our system to render a view of the sender depending on the receiver's viewpoint. The resulting motion parallax gives the receivers a strong impression of 3D viewing as they move, yet the system only needs an ordinary 2D display. This is cheaper than a full3 D system, and avoids disadvantages such as the need to wear shutter glasses, VR headsets, or to sit in a particular position required by an autostereo display.Perceptual studies show that users experience a greater sensation of depth with our system compared to a typical 2D videoconferencing system.展开更多
Exhaled ammonia(NH_(3))can be used as a crucial biomarker of kidney and liver diseases.However,the high humidity in the detection conditions remains a challenge for accurate detection by gas sensors.Herein,a copper-ba...Exhaled ammonia(NH_(3))can be used as a crucial biomarker of kidney and liver diseases.However,the high humidity in the detection conditions remains a challenge for accurate detection by gas sensors.Herein,a copper-based metal-organic framework(CH_(3)-Cu-BTC)with methyl(CH_(3)^(-))functionalization of trimesic acid was synthesized for NH_(3) colorimetric sensing.The CH_(3)-Cu-BTC exhibited a strong response for 5 ppm NH_(3) with high selectivity under high relative humidity(75%RH).Density functional theory(DFT)simulations indicated that the NH_(3) molecules interacted more strongly with CH_(3)-Cu-BTC than H_(2)O molecules did,and the corresponding color switching was attributed to the lone-pair electron in NH_(3) changing the coordination environment of Cu^(2+)ions,leading to an obviously visible color switching response from ruby green to blue.Based on the tailor-made pore chemistry,the precise detection of trace amounts of NH_(3) in exhaled air was realized through functionalized MOF materials.The strategy used in this study not only offers a new pathway for the rapid detection of low concentration NH_(3) under humid conditions,but also shows a method for early respiration diagnosis of kidney and liver diseases.展开更多
Despite sufficient studies performed in non-primate animal models,there exists scanty information obtained from pilot trials in non-human primate animal models,severely hindering nanomaterials moving from basic resear...Despite sufficient studies performed in non-primate animal models,there exists scanty information obtained from pilot trials in non-human primate animal models,severely hindering nanomaterials moving from basic research into clinical practice.We herein present a pioneering demonstration of nanomaterials based optical imaging-guided surgical operation by using macaques as a typical kind of non-human primate-animal models.Typically,taking advantages of strong and stable fluorescence of the small-sized(diameter:~5 nm)silicon-based nanoparticles(SiNPs),lymphatic drainage patterns can be vividly visualized in a real-time manner,and lymph nodes(LN)are able to be sensitively detected and precisely excised from small animal models(e.g.,rats and rabbits)to non-human primate animal models(e.g.,cynomolgus macaque(Macaca fascicularis)and rhesus macaque(Macaca mulatta)).Compared to clinically used invisible near-infrared(NIR)lymphatic tracers(i.e.,indocyanine green(ICG);etc.),we fully indicate that the SiNPs feature unique advantages for naked-eye visible fluorescence-guided surgical operation in long-term manners.Thorough toxicological analysis in macaque models further provides confirming evidence of favorable biocompatibility of the SiNPs probes.We expect that our findings would facilitate the translation of nanomaterials from the laboratory to the clinic,especially in the field of cancer treatment.展开更多
A simple colorimetric acetate ion receptor based on 3-methoxysalicylaldehyde-4＇-nitrophenyl-hydrazone was synthesized in an ethanol solution through one step,and characterized by 1H NMR and elemental analyses.Its ani...A simple colorimetric acetate ion receptor based on 3-methoxysalicylaldehyde-4＇-nitrophenyl-hydrazone was synthesized in an ethanol solution through one step,and characterized by 1H NMR and elemental analyses.Its anion-binding ability was examined by UV-Vis absorption spectroscopy in DMSO（dimethyl sulfoxide）.The result shows that the compound has a high affinity for and a high selectivity toward acetate ions,and also an advantage of ＇naked-eye＇ recognition of color changing from yellow to purple.展开更多
A terpyridine derivative DPTP [di-（4-methylphenyl）-2,2＇：6＇,2＂-terpyridine] was conveniently synthesized from 2-bromopyridine via halogen-dance reaction, Kharash coupling and Stille coupling reaction. Then its co...A terpyridine derivative DPTP [di-（4-methylphenyl）-2,2＇：6＇,2＂-terpyridine] was conveniently synthesized from 2-bromopyridine via halogen-dance reaction, Kharash coupling and Stille coupling reaction. Then its corresponding ruthenium complex Ru-DPTP [N,N,N-4,4＇＇-di-（4-methy,phenyl）-2,2＇：6＇,2＂-terpyridine-N,N,N-tris（is,-thi,cyanat,）- ruthenium（H） ammonium] was obtained and fully characterized by IR, UV-Vis, ESI MS and elemental analysis. The MLCT absorption band of Ru-DPTP was blue-shifted from 570 to 500 nm upon addition of Hg^2＋. Among a series of surveyed metal ions, the complex showed a unique recognition to Hg^2＋, indicating that it can be used as a selective colorimetric sensor for Hg^2＋.展开更多
基金supported by the National Natural Science Foundation of China （Nos. 21272069, 20672035）, the Fundamental Research Funds for the Central Universities and Baihehua Group.
文摘A novel colorimetric chemosensor PBIOSi has been designed and synthesized. The addition of F to a THF solution of PBIOSi resulted in an obvious color change （from red to green） in a short time because of the specific cleavage of Si-O bond in PBIOSi by F-. It was interesting that PBIOSi showed excellent selectivity for F detection over other halides. The UV-Vis absorption and fluorescence were changed linearly with the concentration ofF over the range of 0- 10 μmol/L.
基金supported by the National Hightech R&D Program of China (Project No. 2013AA013903)the National Natural Science Foundation of China (Project Nos. 61133008 and 61272226)+1 种基金Research Grant of Beijing Higher Institution Engineering Research Center, an EPSRC Travel Grantthe Research and Enterprise Investment Fund of Cardiff Metropolitan University
文摘We consider a face-to-face videoconferencing system that uses a Kinect camera at each end of the link for 3D modeling and an ordinary2 D display for output. The Kinect camera allows a 3D model of each participant to be transmitted;the(assumed static) background is sent separately.Furthermore, the Kinect tracks the receiver's head,allowing our system to render a view of the sender depending on the receiver's viewpoint. The resulting motion parallax gives the receivers a strong impression of 3D viewing as they move, yet the system only needs an ordinary 2D display. This is cheaper than a full3 D system, and avoids disadvantages such as the need to wear shutter glasses, VR headsets, or to sit in a particular position required by an autostereo display.Perceptual studies show that users experience a greater sensation of depth with our system compared to a typical 2D videoconferencing system.
基金the financial support from the National Natural Science Foundation of China(Nos.22090062,22278287,22278288)the Shanxi Province 136 Revitalization Medical Project(General Surgery Department)+1 种基金the Shanxi Provincial Guiding Science and Technology Special Project(No.2021XM42)the Basic Research Program of Shanxi Province(No.202103021224341)。
文摘Exhaled ammonia(NH_(3))can be used as a crucial biomarker of kidney and liver diseases.However,the high humidity in the detection conditions remains a challenge for accurate detection by gas sensors.Herein,a copper-based metal-organic framework(CH_(3)-Cu-BTC)with methyl(CH_(3)^(-))functionalization of trimesic acid was synthesized for NH_(3) colorimetric sensing.The CH_(3)-Cu-BTC exhibited a strong response for 5 ppm NH_(3) with high selectivity under high relative humidity(75%RH).Density functional theory(DFT)simulations indicated that the NH_(3) molecules interacted more strongly with CH_(3)-Cu-BTC than H_(2)O molecules did,and the corresponding color switching was attributed to the lone-pair electron in NH_(3) changing the coordination environment of Cu^(2+)ions,leading to an obviously visible color switching response from ruby green to blue.Based on the tailor-made pore chemistry,the precise detection of trace amounts of NH_(3) in exhaled air was realized through functionalized MOF materials.The strategy used in this study not only offers a new pathway for the rapid detection of low concentration NH_(3) under humid conditions,but also shows a method for early respiration diagnosis of kidney and liver diseases.
基金the National Natural Science Foundation of China(Nos.21825402,31400860,22393932,T2321005,and 22204117)the Science and Technology Development Fund,Macao SAR(Nos.0002/2022/AKP and 0115/2023/RIA2)+3 种基金the National Key R&D Program of China(No.2023YFB3208200)the Natural Science Foundation of Jiangsu Province of China(Nos.BK20191417 and BK20170061)the Program for Jiangsu Specially Appointed Professors to Y.H.,a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)111 Project and Collaborative Innovation Center of Suzhou Nano Science and Technology(NANO-CIC).
文摘Despite sufficient studies performed in non-primate animal models,there exists scanty information obtained from pilot trials in non-human primate animal models,severely hindering nanomaterials moving from basic research into clinical practice.We herein present a pioneering demonstration of nanomaterials based optical imaging-guided surgical operation by using macaques as a typical kind of non-human primate-animal models.Typically,taking advantages of strong and stable fluorescence of the small-sized(diameter:~5 nm)silicon-based nanoparticles(SiNPs),lymphatic drainage patterns can be vividly visualized in a real-time manner,and lymph nodes(LN)are able to be sensitively detected and precisely excised from small animal models(e.g.,rats and rabbits)to non-human primate animal models(e.g.,cynomolgus macaque(Macaca fascicularis)and rhesus macaque(Macaca mulatta)).Compared to clinically used invisible near-infrared(NIR)lymphatic tracers(i.e.,indocyanine green(ICG);etc.),we fully indicate that the SiNPs feature unique advantages for naked-eye visible fluorescence-guided surgical operation in long-term manners.Thorough toxicological analysis in macaque models further provides confirming evidence of favorable biocompatibility of the SiNPs probes.We expect that our findings would facilitate the translation of nanomaterials from the laboratory to the clinic,especially in the field of cancer treatment.
基金Supported by the National Natural Science Foundation of China(Nos.20371028,20671052)the Doctor Foundation of Tianjin Normal University,China(No.52LX31)
文摘A simple colorimetric acetate ion receptor based on 3-methoxysalicylaldehyde-4＇-nitrophenyl-hydrazone was synthesized in an ethanol solution through one step,and characterized by 1H NMR and elemental analyses.Its anion-binding ability was examined by UV-Vis absorption spectroscopy in DMSO（dimethyl sulfoxide）.The result shows that the compound has a high affinity for and a high selectivity toward acetate ions,and also an advantage of ＇naked-eye＇ recognition of color changing from yellow to purple.
文摘A terpyridine derivative DPTP [di-（4-methylphenyl）-2,2＇：6＇,2＂-terpyridine] was conveniently synthesized from 2-bromopyridine via halogen-dance reaction, Kharash coupling and Stille coupling reaction. Then its corresponding ruthenium complex Ru-DPTP [N,N,N-4,4＇＇-di-（4-methy,phenyl）-2,2＇：6＇,2＂-terpyridine-N,N,N-tris（is,-thi,cyanat,）- ruthenium（H） ammonium] was obtained and fully characterized by IR, UV-Vis, ESI MS and elemental analysis. The MLCT absorption band of Ru-DPTP was blue-shifted from 570 to 500 nm upon addition of Hg^2＋. Among a series of surveyed metal ions, the complex showed a unique recognition to Hg^2＋, indicating that it can be used as a selective colorimetric sensor for Hg^2＋.
