Based on the concept of "active blocks" and spatial distribution of historical earthquakes with surface ruptures as well as major and subordinate active faults. The Sichuan-Yunnan region can be divided into ...Based on the concept of "active blocks" and spatial distribution of historical earthquakes with surface ruptures as well as major and subordinate active faults. The Sichuan-Yunnan region can be divided into four first-order blocks. They are the Markam block (I), the Sichuan-Yunnan rhombic block (II), Baoshan-Pu'er block (III), and Mizhina-Ximeng block (IV). Cut by sub-ordinate NE-trending active faults, the Sichuan-Yunnan rhombic block (II) can be further divided into two sub-blocks: the northwestern Sichuan sub-block (II1) and the middle Yunnan sub-block (II2), while the Baoshan- Pu'er block (III) can be further divided into three sub-blocks: Baoshan sub-block (III1), Jinggu sub-block (III2), and Mengla sub-block (III3). A quantitative study of offset landforms is carried out and the basic types of active faults and their long-term slip rates along the major boundaries of active blocks of different orders in the Sichuan-Yunnan region are determined, through slip vector analysis, the motion states of the active blocks are clarified and the deformation coordination on the block margins is discussed. It is suggested that the tectonic motion of the blocks in this region is a complex or superimposition of three basic types of motions: southeastward sliding, rotating on vertical axis, and uplifting. The Markam block (I), the northwestern Sichuan sub-block (II1), and middle Yunnan sub-block (II2) have a southeastward horizontal sliding rate of 1-5 mm/a, clockwise rotating angular rate of 1.4-4(/Ma, and uplifting rate of about 1 mm/a. The Baoshan-Pu'er (III) and Mizhina-Ximeng (IV) blocks have also been extensively clockwise rotated. This pattern of motion is a strain response to the collision between the Indian and Eurasian plates and the localized deformation and differential slip on the block margins associated with the northward motion of the Indian Plate. Because a set of transverse thrusts between the blocks absorbs and transforms some components of eastward or southeastward sliding motion, the eastward escape or 展开更多
The National Strong Motion Observation Network System (NSMONS) of China is briefly introduced in this paper. The NSMONS consists of permanent free-field stations, special observation arrays, mobile observatories and...The National Strong Motion Observation Network System (NSMONS) of China is briefly introduced in this paper. The NSMONS consists of permanent free-field stations, special observation arrays, mobile observatories and a network management system. During the Wenchuan Earthquake, over 1,400 components of acceleration records were obtained from 460 permanent free-field stations and three arrays for topographical effect and structural response observation in the network system from the main shock, and over 20,000 components of acceleration records from strong aftershocks occurred before August 1, 2008 were also obtained by permanent free-field stations of the NSMONS and 59 mobile instruments quickly deployed after the main shock. The strong motion recordings from the main shock and strong aftershocks are summarized in this paper. In the ground motion recordings, there are over 560 components with peak ground acceleration (PGA) over 10 Gal, the largest being 957.7 Gal. The largest PGA recorded during the aftershock exceeds 300 Gal.展开更多
After a brief review of studies on artificial boundaries in dynamic soil-structure interaction, a three-dimensional viscous-spring artificial boundary (VSAB) in the time domain is developed in this paper. First, the...After a brief review of studies on artificial boundaries in dynamic soil-structure interaction, a three-dimensional viscous-spring artificial boundary (VSAB) in the time domain is developed in this paper. First, the 3D VSAB equations in the normal and tangential directions are derived based on the elastic wave motion theory. Secondly, a numerical simulation technique of wave motion equations along with the VSAB condition in the time domain is studied. Finally, numerical examples of some classical elastic wave motion problems are presented and the results are compared with the associated theoretical solutions, demonstrating that high precision and adequate stability can be achieved by using the proposed 3D VSAB. The proposed 3D VSAB can be conveniently incorporated in the general finite element program, which is commonly used to study dynamic soil-structure interaction problems.展开更多
This is a survey on normal distributions and the related central limit theorem under sublinear expectation.We also present Brownian motion under sublinear expectations and the related stochastic calculus of It's t...This is a survey on normal distributions and the related central limit theorem under sublinear expectation.We also present Brownian motion under sublinear expectations and the related stochastic calculus of It's type.The results provide new and robust tools for the problem of probability model uncertainty arising in financial risk,statistics and other industrial problems.展开更多
The recently built China Digital Seismic Network consists of the China National Digital Seismic Network (CNDSN), 31 regional seismic networks and several small aperture arrays with more than 1 000 stations including...The recently built China Digital Seismic Network consists of the China National Digital Seismic Network (CNDSN), 31 regional seismic networks and several small aperture arrays with more than 1 000 stations including 850+ broadband stations. It forms a gigantic seismic array that provides an unprecedented opportunity to study the Earth's deep interior besides its routine task of seismic monitoring. Many modern seismic studies rely on rotation of vertical and horizontal components in order to separate different types of seismic waves. Knowledge of the orientations of the two horizontal components thus is important to perform a correction rotation. We analyzed particle motions of teleseismic P waves recorded by the network and used them to estimate the northcomponent azimuth of each station. An SNR-weighted-multi-event method was introduced to obtain component azimuths that best explain the P-wave particle motions of all the events recorded at a station. The method provides robust estimates including a measurement error calculated from background noise levels. We found that about one third of the stations have some sort of problems, including misorientation of the two horizontal components, mislabeling and polarity reversal in one or more components. These problems need to be taken into account for any rotation based seismic studies.展开更多
Impacts of the MJO on winter rainfall and circulation in China are investigated using a real-time multivariate MJO index.Composite results using the daily rainfall anomalies and "rainy day" anomalies accordi...Impacts of the MJO on winter rainfall and circulation in China are investigated using a real-time multivariate MJO index.Composite results using the daily rainfall anomalies and "rainy day" anomalies according to eight different MJO phases show that the MJO has considerable influence on winter rainfall in China. Rainfall anomalies show systematic and substantial changes(enhanced/suppressed) in the Yangtze River Basin and South China with the eastward propagation of the MJO convective center from the Indian Ocean to the western Pacific.When the MJO is in phase 2 and 3(MJO convective center is located over the Indian Ocean),rainfall probability is significantly enhanced.While in phase 6 and 7(MJO convective center is over the western Pacific),rainfall probability is significantly reduced. MJO in winter influences the rainfall in China mainly through modulating the circulation in the subtropics and mid-high latitudes.For the subtropics,MJO influences the northward moisture transport coming from the Bay of Bengal and the South China Sea by modulating the southern trough of the Bay of Bengal and the western Pacific subtropical high.For the mid-high latitudes,the propagation of the low frequency perturbations associated with the eastward-propagating MJO convection modulate the circulation in the mid-high latitudes,e.g.the East Asian winter monsoon and the low trough over central Asia.展开更多
During the last 20 years, studies on active tectonics in China have entered a new quan-titative research stage and made a great progress. Summing up the quantitative results, a Map of Active Tectonics of China on the ...During the last 20 years, studies on active tectonics in China have entered a new quan-titative research stage and made a great progress. Summing up the quantitative results, a Map of Active Tectonics of China on the scale of 1︰4 million has been compiled. In the map all types of active tectonics and their kinematic parameters are reflected in possible detail, such as active faults, active folds, active basins, active blocks, volcanoes, and earthquakes. This paper summa-rizes the basic characteristics of active tectonics of China. The Himalaya Mountains and Taiwan Island are major plate boundaries where the slip rates are larger than 15 mm/a. Tectonic activity in the continental intraplate region is characterized by block motion. The crust and lithosphere in the region were dissected into blocks with different orders. Of them the Qinghai-Xizang (Tibet), Xin- jiang, and North China block regions exhibit the most recent tectonic activity. The kinematic char-acteristics of more than 200 active tectonic zones indicate that the intraplate tectonic activity represents a block motion at a limited low rate. Horizontal slip rate along the tectonic boundary belts between the blocks is generally less than 10 mm/a, and 10—15 mm/a in maximum, and hence it does not support the continental escape theory of high rate of slip.展开更多
AIM To compare intravoxel incoherent motion(IVIM)-derived parameters with conventional diffusion-weighted imaging(DWI) parameters in predicting the histological grade of hepatocellular carcinoma(h CC) and to evaluate ...AIM To compare intravoxel incoherent motion(IVIM)-derived parameters with conventional diffusion-weighted imaging(DWI) parameters in predicting the histological grade of hepatocellular carcinoma(h CC) and to evaluate the correlation between the parameters and the histological grades.METHODS A retrospective study was performed. Sixty-two patients with surgically confirmed h CCs underwent diffusion-weighted magnetic resonance imaging with twelve b values(10-1200 s/mm^2). The apparent diffusion coefficient(ADC), pure diffusion coefficient(D), pseudo-diffusion coefficient(D*), and perfusion fraction(f) were calculated by two radiologists. The IVIM and conventional DWI parameters were compared among the different grades by using analysis of variance(ANOVA) and the Kruskal-Wallis test. Receiver operating characteristic(ROC) analysis was performed to evaluate the diagnostic efficiency of distinguishing between low-grade(grade 1, G1) and high-grade(grades 2 and 3, G2 and G3) hC C. The correlation between the parameters and the histological grades was assessed by using the Spearman correlation test. Bland-Altman analysis was used to evaluate the reproducibility of the two radiologists' measurements.RESULTS The differences in the ADC and D values among the groups with G1, G2, and G3 histological grades of HCCs were statistically significant(P < 0.001). The D* and f values had no significant differences among the different histological grades of h CC(P > 0.05). The ROC analyses demonstrated that the D and ADC values had better diagnostic performance in differentiating the low-grade h CC from the high-grade h CC, with areas under the curve(AUCs) of 0.909 and 0.843, respectively, measured by radiologist 1 and of 0.911 and 0.852, respectively, measured by radiologist 2. The following significant correlations were obtained between the ADC, D, and D~* values and the histological grades: r =-0.619(P < 0.001), r =-0.628(P < 0.001), and r =-0.299(P = 0.018), respectively, as measured by radiologist 1; r =-0.622(P < 0.001), r =-0.63展开更多
Background: Diffusion-weighted imaging (DWI) with the intravoxel incoherent motion (IVIM) model has shown promising results for providing both diffusion and perfusion intbrmation in cervical cancer; however, its ...Background: Diffusion-weighted imaging (DWI) with the intravoxel incoherent motion (IVIM) model has shown promising results for providing both diffusion and perfusion intbrmation in cervical cancer; however, its use to predict and monitor the efficacy ofneoadjuvant chemotherapy (NACT) in cervical cancer is relatively rare. The study aimed to evaluate the use of DWl with 1VIM and monoexponential models to predict and monitor the efficacy of NACT in cervical cancer. Methods: Forty-two patients with primary cervical cancer underwent magnetic resonance exams at 3 time points (pre-NACT, 3 weeks after the first NACT cycle, and 3 weeks after the second NACT cycle). The response to treatment was determined according to the response evaluation criteria in solid tumors 3 weeks after the second NACT treatment, and the subjects were classified as two groups: responders and nonresponders groups. The apparent diffusion coefficient (ADC), true diffusion coefficient (D), perfusion-related pseudo-diffusion coefficient (D*), and perfusion fraction (f) values were determined. The differences in IVlM-derived variables and ADC between the different groups at the different time points were calculated using an independent samples t-test. Results: The D and ADC values were all significantly higher for the responders than tbr the nonresponders at all 3 time points, but no significant differences were observed in the D* and fvalues. An analysis of the receiver operating characteristic (ROC) curves indicated that a D value threshold 〈0.93 × 10 3 mm2/s and an ADC threshold 〈1.11× 10 3 mm2/s could differentiate responders from nonresponders at pre-NACT time point, yielding area under the curve (AUC) of which were 0.771 and 0.806, respectively. The ROC indicated that the AUCs of D and ADC at the 3 weeks after the first NACT cycle and 3 weeks after the second NACT cycle were 0.823, 0.763, and 0.787, 0.794, respectively. The AUC values of D and ADC at these 3 time points were not signifi展开更多
We obtain the preliminary result of crustal deformation velocity field for the Chinese con-tinent by analyzing GPS data from the Crustal Motion Observation Network of China (CMONOC), particularly the data from the reg...We obtain the preliminary result of crustal deformation velocity field for the Chinese con-tinent by analyzing GPS data from the Crustal Motion Observation Network of China (CMONOC), particularly the data from the regional networks of CMONOC observed in 1999 and 2001. We de-lineate 9 tectonically active blocks and 2 broadly distributed deformation zones out of a denseGPS velocity field, and derive block motion Euler poles for the blocks and their relative motionrates. Our result reveals that there are 3 categories of deformation patterns in the Chinese conti-nent. The first category, associated with the interior of the Tibetan Plateau and the Tianshan oro-genic belt, shows broadly distributed deformation within the regions. The third category, associatedwith the Tarim Basin and the region east of the north-south seismic belt of China, shows block-likemotion, with deformation accommodated along the block boundaries only. The second category, mainly associated with the borderland of the Tibetan Plateau, such as the Qaidam, Qilian, Xining(in eastern Qinghai), and the Diamond-shaped (in western Sichuan and Yunnan) blocks, has thedeformation pattern between the first and the third, i.e. these regions appear to deform block-like,but with smaller sizes and less strength for the blocks. Based on the analysis of the lithosphericstructures and the deformation patterns of the regions above, we come to the inference that thedeformation modes of the Chinese continental crust are mainly controlled by the crustal structure.The crust of the eastern China and the Tarim Basin is mechanically strong, and its deformationtakes the form of relative motion between rigid blocks. On the other hand, the northward indentation of the Indian plate into the Asia continent has created the uplift of the Tibetan Plateau and the Tianshan Mountains, thickened their crust, and raised the temperature in the crust. The lower crust thus has become ductile, evidenced in low seismic velocity and high electric conductivity observed. The brittle part of t展开更多
The equations of motion of an insect with flapping wings are derived and then simplified to that of a flying body using the "rigid body" assumption. On the basis of the simplified equations of motion, the longitudin...The equations of motion of an insect with flapping wings are derived and then simplified to that of a flying body using the "rigid body" assumption. On the basis of the simplified equations of motion, the longitudinal dynamic flight stability of four insects (hoverfly, cranefly, dronefly and hawkmoth) in hovering flight is studied (the mass of the insects ranging from 11 to 1,648 mg and wingbeat frequency from 26 to 157Hz). The method of computational fluid dynamics is used to compute the aerodynamic derivatives and the techniques of eigenvalue and eigenvector analysis are used to solve the equations of motion. The validity of the "rigid body" assumption is tested and how differences in size and wing kinematics influence the applicability of the "rigid body" assumption is investigated. The primary findings are: (1) For insects considered in the present study and those with relatively high wingbeat frequency (hoverfly, drone fly and bumblebee), the "rigid body" assumption is reasonable, and for those with relatively low wingbeat frequency (cranefly and howkmoth), the applicability of the "rigid body" assumption is questionable. (2) The same three natural modes of motion as those reported recently for a bumblebee are identified, i.e., one unstable oscillatory mode, one stable fast subsidence mode and one stable slow subsidence mode. (3) Approximate analytical expressions of the eigenvalues, which give physical insight into the genesis of the natural modes of motion, are derived. The expressions identify the speed derivative Mu (pitching moment produced by unit horizontal speed) as the primary source of the unstable oscillatory mode and the stable fast subsidence mode and Zw (vertical force produced by unit vertical speed) as the primary source of the stable slow subsidence mode.展开更多
文摘Based on the concept of "active blocks" and spatial distribution of historical earthquakes with surface ruptures as well as major and subordinate active faults. The Sichuan-Yunnan region can be divided into four first-order blocks. They are the Markam block (I), the Sichuan-Yunnan rhombic block (II), Baoshan-Pu'er block (III), and Mizhina-Ximeng block (IV). Cut by sub-ordinate NE-trending active faults, the Sichuan-Yunnan rhombic block (II) can be further divided into two sub-blocks: the northwestern Sichuan sub-block (II1) and the middle Yunnan sub-block (II2), while the Baoshan- Pu'er block (III) can be further divided into three sub-blocks: Baoshan sub-block (III1), Jinggu sub-block (III2), and Mengla sub-block (III3). A quantitative study of offset landforms is carried out and the basic types of active faults and their long-term slip rates along the major boundaries of active blocks of different orders in the Sichuan-Yunnan region are determined, through slip vector analysis, the motion states of the active blocks are clarified and the deformation coordination on the block margins is discussed. It is suggested that the tectonic motion of the blocks in this region is a complex or superimposition of three basic types of motions: southeastward sliding, rotating on vertical axis, and uplifting. The Markam block (I), the northwestern Sichuan sub-block (II1), and middle Yunnan sub-block (II2) have a southeastward horizontal sliding rate of 1-5 mm/a, clockwise rotating angular rate of 1.4-4(/Ma, and uplifting rate of about 1 mm/a. The Baoshan-Pu'er (III) and Mizhina-Ximeng (IV) blocks have also been extensively clockwise rotated. This pattern of motion is a strain response to the collision between the Indian and Eurasian plates and the localized deformation and differential slip on the block margins associated with the northward motion of the Indian Plate. Because a set of transverse thrusts between the blocks absorbs and transforms some components of eastward or southeastward sliding motion, the eastward escape or
基金NSFC Under Grant No. 90715038MOST of China Under Grant No. 2006BAC13B02
文摘The National Strong Motion Observation Network System (NSMONS) of China is briefly introduced in this paper. The NSMONS consists of permanent free-field stations, special observation arrays, mobile observatories and a network management system. During the Wenchuan Earthquake, over 1,400 components of acceleration records were obtained from 460 permanent free-field stations and three arrays for topographical effect and structural response observation in the network system from the main shock, and over 20,000 components of acceleration records from strong aftershocks occurred before August 1, 2008 were also obtained by permanent free-field stations of the NSMONS and 59 mobile instruments quickly deployed after the main shock. The strong motion recordings from the main shock and strong aftershocks are summarized in this paper. In the ground motion recordings, there are over 560 components with peak ground acceleration (PGA) over 10 Gal, the largest being 957.7 Gal. The largest PGA recorded during the aftershock exceeds 300 Gal.
基金National Natural Science Foundation of ChinaUnder Grant No.50478014Special Funds for Major State Basic Research Project Under Grant No.2002CB412706Research Funds from National Civil Defense Oficce of Chinafor the Tenth Five-year Plan。
文摘After a brief review of studies on artificial boundaries in dynamic soil-structure interaction, a three-dimensional viscous-spring artificial boundary (VSAB) in the time domain is developed in this paper. First, the 3D VSAB equations in the normal and tangential directions are derived based on the elastic wave motion theory. Secondly, a numerical simulation technique of wave motion equations along with the VSAB condition in the time domain is studied. Finally, numerical examples of some classical elastic wave motion problems are presented and the results are compared with the associated theoretical solutions, demonstrating that high precision and adequate stability can be achieved by using the proposed 3D VSAB. The proposed 3D VSAB can be conveniently incorporated in the general finite element program, which is commonly used to study dynamic soil-structure interaction problems.
基金supported by National Basic Research Program of China (Grant No.2007CB814900)(Financial Risk)
文摘This is a survey on normal distributions and the related central limit theorem under sublinear expectation.We also present Brownian motion under sublinear expectations and the related stochastic calculus of It's type.The results provide new and robust tools for the problem of probability model uncertainty arising in financial risk,statistics and other industrial problems.
基金supported by NSF grant EAR-063566(F.N.)National Natural Science Foundation of China grant 40774042(J.L.)
文摘The recently built China Digital Seismic Network consists of the China National Digital Seismic Network (CNDSN), 31 regional seismic networks and several small aperture arrays with more than 1 000 stations including 850+ broadband stations. It forms a gigantic seismic array that provides an unprecedented opportunity to study the Earth's deep interior besides its routine task of seismic monitoring. Many modern seismic studies rely on rotation of vertical and horizontal components in order to separate different types of seismic waves. Knowledge of the orientations of the two horizontal components thus is important to perform a correction rotation. We analyzed particle motions of teleseismic P waves recorded by the network and used them to estimate the northcomponent azimuth of each station. An SNR-weighted-multi-event method was introduced to obtain component azimuths that best explain the P-wave particle motions of all the events recorded at a station. The method provides robust estimates including a measurement error calculated from background noise levels. We found that about one third of the stations have some sort of problems, including misorientation of the two horizontal components, mislabeling and polarity reversal in one or more components. These problems need to be taken into account for any rotation based seismic studies.
基金supported by the National Natural Science Foundation of China (40905035)the National Basic Research Program of China (973 Program,Grant No.2010CB428606)+2 种基金the National Department Public Benefit Research Foundation of China(GYHY200806004)the Science Foundation of China(U0833602)the Key Technologies R&D Program of China under Grant Nos.2009BAC51B00 and 2007BAC29B04.
文摘Impacts of the MJO on winter rainfall and circulation in China are investigated using a real-time multivariate MJO index.Composite results using the daily rainfall anomalies and "rainy day" anomalies according to eight different MJO phases show that the MJO has considerable influence on winter rainfall in China. Rainfall anomalies show systematic and substantial changes(enhanced/suppressed) in the Yangtze River Basin and South China with the eastward propagation of the MJO convective center from the Indian Ocean to the western Pacific.When the MJO is in phase 2 and 3(MJO convective center is located over the Indian Ocean),rainfall probability is significantly enhanced.While in phase 6 and 7(MJO convective center is over the western Pacific),rainfall probability is significantly reduced. MJO in winter influences the rainfall in China mainly through modulating the circulation in the subtropics and mid-high latitudes.For the subtropics,MJO influences the northward moisture transport coming from the Bay of Bengal and the South China Sea by modulating the southern trough of the Bay of Bengal and the western Pacific subtropical high.For the mid-high latitudes,the propagation of the low frequency perturbations associated with the eastward-propagating MJO convection modulate the circulation in the mid-high latitudes,e.g.the East Asian winter monsoon and the low trough over central Asia.
基金The research was supported by National Key Basic Research Program(Grant No.1998040701)Key Research Project of the 9th Five-Year Plan of China Seismological Bureau(Grant No.95040701).
文摘During the last 20 years, studies on active tectonics in China have entered a new quan-titative research stage and made a great progress. Summing up the quantitative results, a Map of Active Tectonics of China on the scale of 1︰4 million has been compiled. In the map all types of active tectonics and their kinematic parameters are reflected in possible detail, such as active faults, active folds, active basins, active blocks, volcanoes, and earthquakes. This paper summa-rizes the basic characteristics of active tectonics of China. The Himalaya Mountains and Taiwan Island are major plate boundaries where the slip rates are larger than 15 mm/a. Tectonic activity in the continental intraplate region is characterized by block motion. The crust and lithosphere in the region were dissected into blocks with different orders. Of them the Qinghai-Xizang (Tibet), Xin- jiang, and North China block regions exhibit the most recent tectonic activity. The kinematic char-acteristics of more than 200 active tectonic zones indicate that the intraplate tectonic activity represents a block motion at a limited low rate. Horizontal slip rate along the tectonic boundary belts between the blocks is generally less than 10 mm/a, and 10—15 mm/a in maximum, and hence it does not support the continental escape theory of high rate of slip.
文摘AIM To compare intravoxel incoherent motion(IVIM)-derived parameters with conventional diffusion-weighted imaging(DWI) parameters in predicting the histological grade of hepatocellular carcinoma(h CC) and to evaluate the correlation between the parameters and the histological grades.METHODS A retrospective study was performed. Sixty-two patients with surgically confirmed h CCs underwent diffusion-weighted magnetic resonance imaging with twelve b values(10-1200 s/mm^2). The apparent diffusion coefficient(ADC), pure diffusion coefficient(D), pseudo-diffusion coefficient(D*), and perfusion fraction(f) were calculated by two radiologists. The IVIM and conventional DWI parameters were compared among the different grades by using analysis of variance(ANOVA) and the Kruskal-Wallis test. Receiver operating characteristic(ROC) analysis was performed to evaluate the diagnostic efficiency of distinguishing between low-grade(grade 1, G1) and high-grade(grades 2 and 3, G2 and G3) hC C. The correlation between the parameters and the histological grades was assessed by using the Spearman correlation test. Bland-Altman analysis was used to evaluate the reproducibility of the two radiologists' measurements.RESULTS The differences in the ADC and D values among the groups with G1, G2, and G3 histological grades of HCCs were statistically significant(P < 0.001). The D* and f values had no significant differences among the different histological grades of h CC(P > 0.05). The ROC analyses demonstrated that the D and ADC values had better diagnostic performance in differentiating the low-grade h CC from the high-grade h CC, with areas under the curve(AUCs) of 0.909 and 0.843, respectively, measured by radiologist 1 and of 0.911 and 0.852, respectively, measured by radiologist 2. The following significant correlations were obtained between the ADC, D, and D~* values and the histological grades: r =-0.619(P < 0.001), r =-0.628(P < 0.001), and r =-0.299(P = 0.018), respectively, as measured by radiologist 1; r =-0.622(P < 0.001), r =-0.63
基金This work was supported by the grants form National Natural Science Foundation of China (No. 81371524 and No. 81271529) and the Hubei Provincial Natural Science Foundation of China (No. 2014CFB298).
文摘Background: Diffusion-weighted imaging (DWI) with the intravoxel incoherent motion (IVIM) model has shown promising results for providing both diffusion and perfusion intbrmation in cervical cancer; however, its use to predict and monitor the efficacy ofneoadjuvant chemotherapy (NACT) in cervical cancer is relatively rare. The study aimed to evaluate the use of DWl with 1VIM and monoexponential models to predict and monitor the efficacy of NACT in cervical cancer. Methods: Forty-two patients with primary cervical cancer underwent magnetic resonance exams at 3 time points (pre-NACT, 3 weeks after the first NACT cycle, and 3 weeks after the second NACT cycle). The response to treatment was determined according to the response evaluation criteria in solid tumors 3 weeks after the second NACT treatment, and the subjects were classified as two groups: responders and nonresponders groups. The apparent diffusion coefficient (ADC), true diffusion coefficient (D), perfusion-related pseudo-diffusion coefficient (D*), and perfusion fraction (f) values were determined. The differences in IVlM-derived variables and ADC between the different groups at the different time points were calculated using an independent samples t-test. Results: The D and ADC values were all significantly higher for the responders than tbr the nonresponders at all 3 time points, but no significant differences were observed in the D* and fvalues. An analysis of the receiver operating characteristic (ROC) curves indicated that a D value threshold 〈0.93 × 10 3 mm2/s and an ADC threshold 〈1.11× 10 3 mm2/s could differentiate responders from nonresponders at pre-NACT time point, yielding area under the curve (AUC) of which were 0.771 and 0.806, respectively. The ROC indicated that the AUCs of D and ADC at the 3 weeks after the first NACT cycle and 3 weeks after the second NACT cycle were 0.823, 0.763, and 0.787, 0.794, respectively. The AUC values of D and ADC at these 3 time points were not signifi
文摘We obtain the preliminary result of crustal deformation velocity field for the Chinese con-tinent by analyzing GPS data from the Crustal Motion Observation Network of China (CMONOC), particularly the data from the regional networks of CMONOC observed in 1999 and 2001. We de-lineate 9 tectonically active blocks and 2 broadly distributed deformation zones out of a denseGPS velocity field, and derive block motion Euler poles for the blocks and their relative motionrates. Our result reveals that there are 3 categories of deformation patterns in the Chinese conti-nent. The first category, associated with the interior of the Tibetan Plateau and the Tianshan oro-genic belt, shows broadly distributed deformation within the regions. The third category, associatedwith the Tarim Basin and the region east of the north-south seismic belt of China, shows block-likemotion, with deformation accommodated along the block boundaries only. The second category, mainly associated with the borderland of the Tibetan Plateau, such as the Qaidam, Qilian, Xining(in eastern Qinghai), and the Diamond-shaped (in western Sichuan and Yunnan) blocks, has thedeformation pattern between the first and the third, i.e. these regions appear to deform block-like,but with smaller sizes and less strength for the blocks. Based on the analysis of the lithosphericstructures and the deformation patterns of the regions above, we come to the inference that thedeformation modes of the Chinese continental crust are mainly controlled by the crustal structure.The crust of the eastern China and the Tarim Basin is mechanically strong, and its deformationtakes the form of relative motion between rigid blocks. On the other hand, the northward indentation of the Indian plate into the Asia continent has created the uplift of the Tibetan Plateau and the Tianshan Mountains, thickened their crust, and raised the temperature in the crust. The lower crust thus has become ductile, evidenced in low seismic velocity and high electric conductivity observed. The brittle part of t
基金The project supported by the National Natural Science Foundation of China(10232010 and 10472008)
文摘The equations of motion of an insect with flapping wings are derived and then simplified to that of a flying body using the "rigid body" assumption. On the basis of the simplified equations of motion, the longitudinal dynamic flight stability of four insects (hoverfly, cranefly, dronefly and hawkmoth) in hovering flight is studied (the mass of the insects ranging from 11 to 1,648 mg and wingbeat frequency from 26 to 157Hz). The method of computational fluid dynamics is used to compute the aerodynamic derivatives and the techniques of eigenvalue and eigenvector analysis are used to solve the equations of motion. The validity of the "rigid body" assumption is tested and how differences in size and wing kinematics influence the applicability of the "rigid body" assumption is investigated. The primary findings are: (1) For insects considered in the present study and those with relatively high wingbeat frequency (hoverfly, drone fly and bumblebee), the "rigid body" assumption is reasonable, and for those with relatively low wingbeat frequency (cranefly and howkmoth), the applicability of the "rigid body" assumption is questionable. (2) The same three natural modes of motion as those reported recently for a bumblebee are identified, i.e., one unstable oscillatory mode, one stable fast subsidence mode and one stable slow subsidence mode. (3) Approximate analytical expressions of the eigenvalues, which give physical insight into the genesis of the natural modes of motion, are derived. The expressions identify the speed derivative Mu (pitching moment produced by unit horizontal speed) as the primary source of the unstable oscillatory mode and the stable fast subsidence mode and Zw (vertical force produced by unit vertical speed) as the primary source of the stable slow subsidence mode.