The risk of dementia increases in patients with cognitive impairment.However,it is not clear what factors contribute to the onset of dementia in those with cognitive impairment.In this prospective cohort study,we will...The risk of dementia increases in patients with cognitive impairment.However,it is not clear what factors contribute to the onset of dementia in those with cognitive impairment.In this prospective cohort study,we will investigate the every-five-year incidence of cognitive impairment and prognostic factors for cognitive impairment.The Jidong cognitive impairment cohort was established from April 2012 to August 2015,during which we recruited 5854 healthy participants(55.1%male)older than 45 years(mean,57 years).Participants received a health examination in the Staff Hospital,Jidong Oilfield Branch,China National Petroleum Corporation.Baseline data and blood samples were collected.Cognitive impairment was evaluated using the Mini-Mental State Examination,and was defined as a Mini-Mental State Examination score of less than 24.Dementia was assessed using the criteria of Diagnostic and Statistical Manual of Mental Disorders(Fourth edition),the International Working Group criteria,and the Mini-Mental State Examination score.The follow-up will continue until December 2024,during which a prognostic model will be constructed.The primary outcome is the presence/absence of dementia and the secondary outcome is quality of life.Baseline screening results showed the following:(1)Cognitive impairment was apparent in 320 participants(5.5%).These participants will be excluded from the Jidong cohort study,and the remaining participants will be followed up.(2)Of the 320 participants with cognitive impairment,there was a significantly higher prevalence of illiteracy than other education levels(35.9%,P<0.05).Age,arterial hypertension,alcohol consumption,and passive smoking differed significantly between the cognitive impairment and healthy groups(P<0.05).Multivariate logistic regression models showed that age(odds ratio[OR]=1.059,95%confidence interval[CI]:1.044-1.074)and arterial hypertension(OR=1.665,95%CI:1.143-2.427)were risk factors for mild cognitive impairment.With the increase of educational level(illiteracy,primary school,ju展开更多
Aims: To identify the impact of social participation, socio-demographic, socio-economic and disease factors on nutritional risk among older persons in Hong Kong. Background: Few published work has investigated the rel...Aims: To identify the impact of social participation, socio-demographic, socio-economic and disease factors on nutritional risk among older persons in Hong Kong. Background: Few published work has investigated the relative risks of social participation, demographic, socioeconomic and disease factors with malnutrition in community-living older people, this study is to investigate the associations of these risk factors on the nutritional status in better nutrition support for the old age group. Design: A crosssectional study. Methods: It was a secondary analysis of a database in a mobile community centre between January 2008 and December 2009. One thousand seven hundred and thirty one participants aged between 54 and 103 were collected. With 319 full Mini Nutritional Assessment (MNA) completed, the participants’ demographic, socio-economic data, diseases, and nutritional status were analyzed with relative risk and 95% confidence interval level to identify the factors that make them vulnerable to nutritional risk. Results: The prevalence of malnutrition in the community-dwelling old was 3.95% and 83.7% of the sample was at risk of malnutrition. Living on allowances, young old who was socially engaged and good relationship with family members were at less risk to malnutrition. Conclusions: Special attention should be taken to these groups as they are prone to develop malnutrition.展开更多
目的老年高血压已经成为威胁老年人群健康的主要疾病之一。随着人口老龄化日益加重,独居老人逐渐增多,老年人对于自身慢性病的管理可能因认知功能、行为功能受限而导致服药错误、延误病情等,严重影响疾病控制进程。本研究针对老年人的...目的老年高血压已经成为威胁老年人群健康的主要疾病之一。随着人口老龄化日益加重,独居老人逐渐增多,老年人对于自身慢性病的管理可能因认知功能、行为功能受限而导致服药错误、延误病情等,严重影响疾病控制进程。本研究针对老年人的认知障碍进行分层指导,旨在改善高血压患者治疗效果。方法选取2016-05-01-2018-04-30青州市海岱苑社区87例老年高血压患者作为研究对象。选用简易智能状态量表(mini-mental state examination,MMSE)对社区老年高血压患者进行评估,根据评估结果划分为无认知障碍及轻、中、重度认知障碍,对后3种状况给予分层指导,并与患者既往高血压控制数据进行对照研究。选取MMSE评分为轻、中、重度痴呆的患者53例进行实验干预,对干预前及干预6个月后服药依从性以及血压水平进行对比。结果MMSE评价结果显示,未定义痴呆组34例(39.1%)、轻度痴呆34例(39.1%)、中度痴呆10例(11.5%)、重度痴呆9例(10.3%)。Morisky自我服药依从性问卷(medication adherence questionnaire,MAQ)结果显示,用药依从性高31例(35.6%),中44例(50.6%),低12例(13.8%)。MMSE与用药依从性呈显著正相关,r=0.660,P<0.001。轻、中及重度痴呆患者血压控制情况及用药依从性均较干预前改善,干预前后各项指标差异有统计学意义,均P<0.05。结论初步证实,根据MMSE量表对老年人认知功能进行分层,并按照层次特点进行健康指导,对控制老年高血压具有一定效果。展开更多
基金supported by the National Natural Science Foundation of China,No.91749205(to YZ),81973112(to YZ),81973138(to DL),81903401(to WJX)the Young Taishan Scholars Program of Shandong Province of China,No.tsqn20161046(to WJX)
文摘The risk of dementia increases in patients with cognitive impairment.However,it is not clear what factors contribute to the onset of dementia in those with cognitive impairment.In this prospective cohort study,we will investigate the every-five-year incidence of cognitive impairment and prognostic factors for cognitive impairment.The Jidong cognitive impairment cohort was established from April 2012 to August 2015,during which we recruited 5854 healthy participants(55.1%male)older than 45 years(mean,57 years).Participants received a health examination in the Staff Hospital,Jidong Oilfield Branch,China National Petroleum Corporation.Baseline data and blood samples were collected.Cognitive impairment was evaluated using the Mini-Mental State Examination,and was defined as a Mini-Mental State Examination score of less than 24.Dementia was assessed using the criteria of Diagnostic and Statistical Manual of Mental Disorders(Fourth edition),the International Working Group criteria,and the Mini-Mental State Examination score.The follow-up will continue until December 2024,during which a prognostic model will be constructed.The primary outcome is the presence/absence of dementia and the secondary outcome is quality of life.Baseline screening results showed the following:(1)Cognitive impairment was apparent in 320 participants(5.5%).These participants will be excluded from the Jidong cohort study,and the remaining participants will be followed up.(2)Of the 320 participants with cognitive impairment,there was a significantly higher prevalence of illiteracy than other education levels(35.9%,P<0.05).Age,arterial hypertension,alcohol consumption,and passive smoking differed significantly between the cognitive impairment and healthy groups(P<0.05).Multivariate logistic regression models showed that age(odds ratio[OR]=1.059,95%confidence interval[CI]:1.044-1.074)and arterial hypertension(OR=1.665,95%CI:1.143-2.427)were risk factors for mild cognitive impairment.With the increase of educational level(illiteracy,primary school,ju
文摘Aims: To identify the impact of social participation, socio-demographic, socio-economic and disease factors on nutritional risk among older persons in Hong Kong. Background: Few published work has investigated the relative risks of social participation, demographic, socioeconomic and disease factors with malnutrition in community-living older people, this study is to investigate the associations of these risk factors on the nutritional status in better nutrition support for the old age group. Design: A crosssectional study. Methods: It was a secondary analysis of a database in a mobile community centre between January 2008 and December 2009. One thousand seven hundred and thirty one participants aged between 54 and 103 were collected. With 319 full Mini Nutritional Assessment (MNA) completed, the participants’ demographic, socio-economic data, diseases, and nutritional status were analyzed with relative risk and 95% confidence interval level to identify the factors that make them vulnerable to nutritional risk. Results: The prevalence of malnutrition in the community-dwelling old was 3.95% and 83.7% of the sample was at risk of malnutrition. Living on allowances, young old who was socially engaged and good relationship with family members were at less risk to malnutrition. Conclusions: Special attention should be taken to these groups as they are prone to develop malnutrition.
文摘目的老年高血压已经成为威胁老年人群健康的主要疾病之一。随着人口老龄化日益加重,独居老人逐渐增多,老年人对于自身慢性病的管理可能因认知功能、行为功能受限而导致服药错误、延误病情等,严重影响疾病控制进程。本研究针对老年人的认知障碍进行分层指导,旨在改善高血压患者治疗效果。方法选取2016-05-01-2018-04-30青州市海岱苑社区87例老年高血压患者作为研究对象。选用简易智能状态量表(mini-mental state examination,MMSE)对社区老年高血压患者进行评估,根据评估结果划分为无认知障碍及轻、中、重度认知障碍,对后3种状况给予分层指导,并与患者既往高血压控制数据进行对照研究。选取MMSE评分为轻、中、重度痴呆的患者53例进行实验干预,对干预前及干预6个月后服药依从性以及血压水平进行对比。结果MMSE评价结果显示,未定义痴呆组34例(39.1%)、轻度痴呆34例(39.1%)、中度痴呆10例(11.5%)、重度痴呆9例(10.3%)。Morisky自我服药依从性问卷(medication adherence questionnaire,MAQ)结果显示,用药依从性高31例(35.6%),中44例(50.6%),低12例(13.8%)。MMSE与用药依从性呈显著正相关,r=0.660,P<0.001。轻、中及重度痴呆患者血压控制情况及用药依从性均较干预前改善,干预前后各项指标差异有统计学意义,均P<0.05。结论初步证实,根据MMSE量表对老年人认知功能进行分层,并按照层次特点进行健康指导,对控制老年高血压具有一定效果。
