为了评估了小动物锥束微型计算机层析图像(micro-CT)中低能X射线散射的大小和对系统成像结果的影响,该文引入了散射率(scatter-to-pri mary ratio,SPR)的概念。采用主射线终止法计算X射线散射率大小,并利用外推拟合法估测直径为0 mm阻...为了评估了小动物锥束微型计算机层析图像(micro-CT)中低能X射线散射的大小和对系统成像结果的影响,该文引入了散射率(scatter-to-pri mary ratio,SPR)的概念。采用主射线终止法计算X射线散射率大小,并利用外推拟合法估测直径为0 mm阻挡物的散射值。用铅板制成的狭缝改变系统成像的锥角大小,讨论了锥束micro-CT中锥角大小与散射率的关系。直径40 mm的均匀树脂模型用来模拟小鼠,当锥角分别为0.247°和5.67°时,X射线散射率分别为4.78%和27.58%。讨论了散射对重建图像均一度和对比度的影响。展开更多
Our previous study showed the early molecular responses of bone in response to obstructive nephropathy in a unilateral ureteral obstruction （UUO） mouse model. Here, we addressed the changes in trabecular bone proper...Our previous study showed the early molecular responses of bone in response to obstructive nephropathy in a unilateral ureteral obstruction （UUO） mouse model. Here, we addressed the changes in trabecular bone properties at greater trochanter, the proximal and the distal metaphysis of femur in UUO mice. The male mice were subjected to UUO （n= 10） or sham operation （n= 10）. All mice were killed on day 7 after the surgical operation. The micro-computed tomography （micro-CT） analysis for different femoral trabecular bone sites demonstrated pathological alterations of trabecular bone mass and micro-networks at greater trochanter as shown by decreases in bone mineral density/bone volume （P〈O.05） and trabecular number （P〈O.05） and increases in trabecular separation （P〈O.01） and bone surface/bone volume （P〈O.05） in UUO mice. The present study demonstrates that UUO-induced unilateral obstructivenephropathy has markedly detrimental effects on the trabecular trochanter of the femur.展开更多
β-TCP ceramic scaffolds were fabricated with selective laser sintering (SLS) in this work. Carbon nanotubes (CNTs) were mixed with porous β-TCP matrix to enhance the mechanical performance of the bone tissue enginee...β-TCP ceramic scaffolds were fabricated with selective laser sintering (SLS) in this work. Carbon nanotubes (CNTs) were mixed with porous β-TCP matrix to enhance the mechanical performance of the bone tissue engineering scaffolds. Scaffold reconstruction and microstructure analysis were fulfilled based on micro-computed tomography (Micro-CT) scanning data. Results show that the strength of scaffold mixed with 0.2% CNTs reaches 0.819 MPa which has been improved by 85.7% compared with that without CNTs. Micro-CT analysis shows that the scaffold has a good interconnectivity, and pore size mainly distributes in the two regions of 60-340 μm and 500-620 μm.展开更多
文摘为了评估了小动物锥束微型计算机层析图像(micro-CT)中低能X射线散射的大小和对系统成像结果的影响,该文引入了散射率(scatter-to-pri mary ratio,SPR)的概念。采用主射线终止法计算X射线散射率大小,并利用外推拟合法估测直径为0 mm阻挡物的散射值。用铅板制成的狭缝改变系统成像的锥角大小,讨论了锥束micro-CT中锥角大小与散射率的关系。直径40 mm的均匀树脂模型用来模拟小鼠,当锥角分别为0.247°和5.67°时,X射线散射率分别为4.78%和27.58%。讨论了散射对重建图像均一度和对比度的影响。
文摘Our previous study showed the early molecular responses of bone in response to obstructive nephropathy in a unilateral ureteral obstruction （UUO） mouse model. Here, we addressed the changes in trabecular bone properties at greater trochanter, the proximal and the distal metaphysis of femur in UUO mice. The male mice were subjected to UUO （n= 10） or sham operation （n= 10）. All mice were killed on day 7 after the surgical operation. The micro-computed tomography （micro-CT） analysis for different femoral trabecular bone sites demonstrated pathological alterations of trabecular bone mass and micro-networks at greater trochanter as shown by decreases in bone mineral density/bone volume （P〈O.05） and trabecular number （P〈O.05） and increases in trabecular separation （P〈O.01） and bone surface/bone volume （P〈O.05） in UUO mice. The present study demonstrates that UUO-induced unilateral obstructivenephropathy has markedly detrimental effects on the trabecular trochanter of the femur.
基金supported by the Innovation Program of Shanghai Municipal Education Commission (Grant No.09YZ34)
文摘β-TCP ceramic scaffolds were fabricated with selective laser sintering (SLS) in this work. Carbon nanotubes (CNTs) were mixed with porous β-TCP matrix to enhance the mechanical performance of the bone tissue engineering scaffolds. Scaffold reconstruction and microstructure analysis were fulfilled based on micro-computed tomography (Micro-CT) scanning data. Results show that the strength of scaffold mixed with 0.2% CNTs reaches 0.819 MPa which has been improved by 85.7% compared with that without CNTs. Micro-CT analysis shows that the scaffold has a good interconnectivity, and pore size mainly distributes in the two regions of 60-340 μm and 500-620 μm.
