This study investigates the motivations of Chinese domestic tourists visiting seismic memorial sites after the great Wenchuan earthquake of 2008, and examines their interpretation of experiences and benefits of the vi...This study investigates the motivations of Chinese domestic tourists visiting seismic memorial sites after the great Wenchuan earthquake of 2008, and examines their interpretation of experiences and benefits of the visits. Recent research on dark tourism has raised the possibility that people are attracted to death and memorial sites in ways different from other tourist attractions. The study used an empirical research design employing questionnaires to collect data from 255 Chinese domestic visitors at seismic memorial sites in west Sichuan. Analysis revealed that the obligation of commemoration mixed with curiosity represents a different set of travel motivation in dark tourism settings than in other kinds of tourism. In addition, the empirical evidence also suggests an interrelated pattern between motivations, experiences and benefits. This study implies that Chinese domestic tourists were attracted in ways different from other tourist attractions both because they tended to fulfill their obligation of commemoration and were interested in destruction; and visitor experiences played an important mediating role between travel motivations and benefits gained.展开更多
A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial con...A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the experts.The Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this meeting.This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these patients.This coordinated effort can minimise delays and give patients a chance for curative treatment and effective palliation.The diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance cholangiopancreato-graphy.Brush cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for diagnosis.However,histopathologic confirmation is not always required before resection.Endoscopic ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for staging.The only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette classification.Selected patients with unresectable hCCA can be considered for liver transplantation.Adjuvant chemotherapy should be offered to patients with a high risk of recurrence.The use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary discussions.Patients with acute cholangitis can be drained with endoscopic or percutaneous biliary drainage.Palliative chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.展开更多
Red cultural site is the carrier of red culture,containing profound revolutionary history and value of the times,we should deeply excavate the intrinsic potential of red cultural sites,pay attention to the ontological...Red cultural site is the carrier of red culture,containing profound revolutionary history and value of the times,we should deeply excavate the intrinsic potential of red cultural sites,pay attention to the ontological protection of red cultural sites,develop and improve the red cultural innovation projects,and strengthen the red culture itself and supporting the construction.This paper takes the old revolutionary area of Luxi as an example,conducts field investigation and visits based on the local county records and party history materials,and investigates a total of five red cultural sites and memorial halls in Luxi,focusing on the actual achievements and problems exposed in the protection and development of the current red cultural sites,to provide references and thinking for the protection,development,and innovative utilization of red cultural sites in the new era of our country.展开更多
Wu Lanfu Memorial Hall is taken as research object. By combining web text analysis with questionnaire research, comprehensive analysis of tourist experience information (thematic background, scenic area services and h...Wu Lanfu Memorial Hall is taken as research object. By combining web text analysis with questionnaire research, comprehensive analysis of tourist experience information (thematic background, scenic area services and hardware infrastructure) of research object is conducted under red tourism perspective. Via further correlation analysis, the dimensions that influence visitors’perception and experience of celebrity memorial hall are found, which attempts to contribute to the more comprehensive promotion of the tourism experience of red tourist attractions. Research results are as below. First, visitors are generally satisfied with the overall perception of celebrity memorial hall, and celebrity memorial hall occupies an indispensable position in the red tourism system. Second, visitors’ potential perception of memorial hall is quite different from their actual perception, and the quality of scenic spots does not match its potential perception. Third, celebrity effect plays a prominent role in red tourism attractions. Fourth, celebrity memorial hall play an important role in the inheritance and dissemination of red culture. Corresponding improvement suggestions are put forward in this paper based on above conclusions, and it aims to provide the reference for the development of red tourism and the spread of red culture in ethnic regions.展开更多
BACKGROUND Gastrointestinal stromal tumors(GISTs) are the most common mesenchymal tumor type in the gastrointestinal system. Presently, various classification systems to prognosticate GISTs have been proposed.AIM To e...BACKGROUND Gastrointestinal stromal tumors(GISTs) are the most common mesenchymal tumor type in the gastrointestinal system. Presently, various classification systems to prognosticate GISTs have been proposed.AIM To evaluate the application value of four different risk stratification systems for GISTs.METHODS Patients who were diagnosed with GISTs and underwent surgical resection at four hospitals from 1998 to 2015 were identified from a database. Risk of recurrence was stratified by the modified National Institute of Health(NIH)criteria, the Armed Forces Institute of Pathology(AFIP) criteria, the Memorial Sloan Kettering Cancer Center(MSKCC) prognostic nomogram, and the contour maps. Receiver operating characteristic(ROC) curves were established to compare the four abovementioned risk stratification systems based on the area under the curve(AUC).RESULTS A total of 1303 patients were included in the study. The mean age of the patients was 55.77 ± 13.70 yr; 52.3% of the patients were male. The mean follow-up period was 64.91 ± 35.79 mo. Approximately 67.0% the tumors were located in the stomach, and 59.5% were smaller than 5 cm; 67.3% of the patients had a mitotic count ≤ 5/50 high-power fields(HPFs). Thirty-four tumors ruptured before and during surgery. Univariate analysis demonstrated that tumor size > 5 cm(P <0.05), mitotic count > 5/50 HPFs(P < 0.05), non-gastric location(P < 0.05), and tumor rupture(P < 0.05) were significantly associated with increased recurrence rates. According to the ROC curve, the AFIP criteria showed the largest AUC(0.754).CONCLUSION According to our data, the AFIP criteria were associated with a larger AUC than the NIH modified criteria, the MSKCC nomogram, and the contour maps, which might indicate that the AFIP criteria have better accuracy to support therapeutic decision-making for patients with GISTs.展开更多
基金supported by the China Scholarship Council(Liujinfa[2011]No.5024)the Key Teachers Development Fellowship Program of CDUT(KYGG201313)the Center for Folk Culture Studies(MJ13-09)
文摘This study investigates the motivations of Chinese domestic tourists visiting seismic memorial sites after the great Wenchuan earthquake of 2008, and examines their interpretation of experiences and benefits of the visits. Recent research on dark tourism has raised the possibility that people are attracted to death and memorial sites in ways different from other tourist attractions. The study used an empirical research design employing questionnaires to collect data from 255 Chinese domestic visitors at seismic memorial sites in west Sichuan. Analysis revealed that the obligation of commemoration mixed with curiosity represents a different set of travel motivation in dark tourism settings than in other kinds of tourism. In addition, the empirical evidence also suggests an interrelated pattern between motivations, experiences and benefits. This study implies that Chinese domestic tourists were attracted in ways different from other tourist attractions both because they tended to fulfill their obligation of commemoration and were interested in destruction; and visitor experiences played an important mediating role between travel motivations and benefits gained.
文摘A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the experts.The Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this meeting.This effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these patients.This coordinated effort can minimise delays and give patients a chance for curative treatment and effective palliation.The diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance cholangiopancreato-graphy.Brush cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for diagnosis.However,histopathologic confirmation is not always required before resection.Endoscopic ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for staging.The only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette classification.Selected patients with unresectable hCCA can be considered for liver transplantation.Adjuvant chemotherapy should be offered to patients with a high risk of recurrence.The use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary discussions.Patients with acute cholangitis can be drained with endoscopic or percutaneous biliary drainage.Palliative chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.
文摘Red cultural site is the carrier of red culture,containing profound revolutionary history and value of the times,we should deeply excavate the intrinsic potential of red cultural sites,pay attention to the ontological protection of red cultural sites,develop and improve the red cultural innovation projects,and strengthen the red culture itself and supporting the construction.This paper takes the old revolutionary area of Luxi as an example,conducts field investigation and visits based on the local county records and party history materials,and investigates a total of five red cultural sites and memorial halls in Luxi,focusing on the actual achievements and problems exposed in the protection and development of the current red cultural sites,to provide references and thinking for the protection,development,and innovative utilization of red cultural sites in the new era of our country.
基金Sponsored by Inner Mongolia University Training Program of Innovation and Entrepreneurship for Undergraduates(201805069)“10,000 Tourism Talents Program”,Ministry of Culture and Tourism of the People’s Republic of China(WMYC20183-005)
文摘Wu Lanfu Memorial Hall is taken as research object. By combining web text analysis with questionnaire research, comprehensive analysis of tourist experience information (thematic background, scenic area services and hardware infrastructure) of research object is conducted under red tourism perspective. Via further correlation analysis, the dimensions that influence visitors’perception and experience of celebrity memorial hall are found, which attempts to contribute to the more comprehensive promotion of the tourism experience of red tourist attractions. Research results are as below. First, visitors are generally satisfied with the overall perception of celebrity memorial hall, and celebrity memorial hall occupies an indispensable position in the red tourism system. Second, visitors’ potential perception of memorial hall is quite different from their actual perception, and the quality of scenic spots does not match its potential perception. Third, celebrity effect plays a prominent role in red tourism attractions. Fourth, celebrity memorial hall play an important role in the inheritance and dissemination of red culture. Corresponding improvement suggestions are put forward in this paper based on above conclusions, and it aims to provide the reference for the development of red tourism and the spread of red culture in ethnic regions.
基金the State Key Project of Research and Development Plan,No.2017YFC0108300 and No.2017YFC01083032018 Special Funds for the Cultivation of Guangdong College Students'Scientific and Technological Innovation(Climbing Program Special Funds),No.pdjha0094
文摘BACKGROUND Gastrointestinal stromal tumors(GISTs) are the most common mesenchymal tumor type in the gastrointestinal system. Presently, various classification systems to prognosticate GISTs have been proposed.AIM To evaluate the application value of four different risk stratification systems for GISTs.METHODS Patients who were diagnosed with GISTs and underwent surgical resection at four hospitals from 1998 to 2015 were identified from a database. Risk of recurrence was stratified by the modified National Institute of Health(NIH)criteria, the Armed Forces Institute of Pathology(AFIP) criteria, the Memorial Sloan Kettering Cancer Center(MSKCC) prognostic nomogram, and the contour maps. Receiver operating characteristic(ROC) curves were established to compare the four abovementioned risk stratification systems based on the area under the curve(AUC).RESULTS A total of 1303 patients were included in the study. The mean age of the patients was 55.77 ± 13.70 yr; 52.3% of the patients were male. The mean follow-up period was 64.91 ± 35.79 mo. Approximately 67.0% the tumors were located in the stomach, and 59.5% were smaller than 5 cm; 67.3% of the patients had a mitotic count ≤ 5/50 high-power fields(HPFs). Thirty-four tumors ruptured before and during surgery. Univariate analysis demonstrated that tumor size > 5 cm(P <0.05), mitotic count > 5/50 HPFs(P < 0.05), non-gastric location(P < 0.05), and tumor rupture(P < 0.05) were significantly associated with increased recurrence rates. According to the ROC curve, the AFIP criteria showed the largest AUC(0.754).CONCLUSION According to our data, the AFIP criteria were associated with a larger AUC than the NIH modified criteria, the MSKCC nomogram, and the contour maps, which might indicate that the AFIP criteria have better accuracy to support therapeutic decision-making for patients with GISTs.
