KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and synonymous (Ks) substitution rates through model selection and model averaging. Since existing methods for this estimation adopt their s...KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and synonymous (Ks) substitution rates through model selection and model averaging. Since existing methods for this estimation adopt their specific mutation (substitution) models that consider different evolutionary features, leading to diverse estimates, KaKs_Calculator implements a set of candidate models in a maximum likelihood framework and adopts the Akaike information criterion to measure fitness between models and data, aiming to include as many features as needed for accurately capturing evolutionary information in protein-coding sequences. In addition, several existing methods for calculating Ka and Ks are also incorporated into this software. KaKs_Calculator, including source codes, compiled executables, and documentation, is freely available for academic use at http://evolution.genomics.org.cn/software.htm.展开更多
Real time remaining useful life(RUL) prediction based on condition monitoring is an essential part in condition based maintenance(CBM). In the current methods about the real time RUL prediction of the nonlinear degrad...Real time remaining useful life(RUL) prediction based on condition monitoring is an essential part in condition based maintenance(CBM). In the current methods about the real time RUL prediction of the nonlinear degradation process, the measurement error is not considered and forecasting uncertainty is large. Therefore, an approximate analytical RUL distribution in a closed-form of a nonlinear Wiener based degradation process with measurement errors was proposed. The maximum likelihood estimation approach was used to estimate the unknown fixed parameters in the proposed model. When the newly observed data are available, the random parameter is updated by the Bayesian method to make the estimation adapt to the item's individual characteristic and reduce the uncertainty of the estimation. The simulation results show that considering measurement errors in the degradation process can significantly improve the accuracy of real time RUL prediction.展开更多
We investigate an optimal harvesting problem for age-structured species,in which elder individuals are more competitive than younger ones,and the population is modeled by a highly nonlinear integro-partial differentia...We investigate an optimal harvesting problem for age-structured species,in which elder individuals are more competitive than younger ones,and the population is modeled by a highly nonlinear integro-partial differential equation with a global feedback boundary condition.The existence of optimal strategies is established by means of compactness and maximizing sequences,and the maximum principle obtained via an adjoint system,tangent-normal cones and a new continuity result.In addition,some numerical experiments are presented to show the effects of the price function and younger's weight on the optimal profits.展开更多
The Ms8.0 Wenchuan earthquake of 2008 dramatically changed the terrain surface and caused long-term increases in the scale and frequency of landslides and debris flows.The changing trend of landslides in the earthquak...The Ms8.0 Wenchuan earthquake of 2008 dramatically changed the terrain surface and caused long-term increases in the scale and frequency of landslides and debris flows.The changing trend of landslides in the earthquake-affected area over the decade since the earthquake remains largely unknown.In this study,we were able to address this issue using supervised classification methods and multitemporal remote sensing images to study landslide evolution in the worst-affected area(Mianyuan River Basin)over a period of ten years.Satellite images were processed using the maximum likelihood method and random forest algorithm to automatically map landslide occurrence from 2007 to 2018.The principal findings are as follows:(1)when compared with visual image analysis,the random forest algorithm had a good average accuracy rate of 87%for landslide identification;(2)postevent landslide occurrence has generally decreased with time,but heavy monsoonal seasons have caused temporary spikes in activity;and(3)the postearthquake landslide activity in the Mianyuan River Basin can be divided into a strong activity period(2008 to 2011),medium activity period(2012 to 2016),and weak activity period(post 2017).Landslide activity remains above the prequake level,with damaging events being rare but continuing to occur.Long-term remote sensing and on-site monitoring are required to understand the evolution of landslide activity after strong earthquakes.展开更多
A new method based on the maximum entropy principle for reconstructing the parton distribution function(PDF)from moments is proposed.Unlike traditional methods,the new method does not require any artificial assumption...A new method based on the maximum entropy principle for reconstructing the parton distribution function(PDF)from moments is proposed.Unlike traditional methods,the new method does not require any artificial assumptions.For the case of moments with errors,we introduce Gaussian functions to soften the constraints of moments.Through a series of tests,the effectiveness and reconstruction efficiency of this new method are evaluated comprehensively,demonstrating that this method is reasonable and can achieve high-quality reconstruction with at least the first six moments as input.Finally,we select a set of lattice quantum chromodynamics(QCD)results regarding moments as input and provide reasonable reconstruction results for the pion.展开更多
基金grants from the Ministry of Science and Technology of China (No. 2001AA231061) the National Natural Science Foundation of China (No. 30270748)
文摘KaKs_Calculator is a software package that calculates nonsynonymous (Ka) and synonymous (Ks) substitution rates through model selection and model averaging. Since existing methods for this estimation adopt their specific mutation (substitution) models that consider different evolutionary features, leading to diverse estimates, KaKs_Calculator implements a set of candidate models in a maximum likelihood framework and adopts the Akaike information criterion to measure fitness between models and data, aiming to include as many features as needed for accurately capturing evolutionary information in protein-coding sequences. In addition, several existing methods for calculating Ka and Ks are also incorporated into this software. KaKs_Calculator, including source codes, compiled executables, and documentation, is freely available for academic use at http://evolution.genomics.org.cn/software.htm.
基金Projects(51475462,61374138,61370031)supported by the National Natural Science Foundation of China
文摘Real time remaining useful life(RUL) prediction based on condition monitoring is an essential part in condition based maintenance(CBM). In the current methods about the real time RUL prediction of the nonlinear degradation process, the measurement error is not considered and forecasting uncertainty is large. Therefore, an approximate analytical RUL distribution in a closed-form of a nonlinear Wiener based degradation process with measurement errors was proposed. The maximum likelihood estimation approach was used to estimate the unknown fixed parameters in the proposed model. When the newly observed data are available, the random parameter is updated by the Bayesian method to make the estimation adapt to the item's individual characteristic and reduce the uncertainty of the estimation. The simulation results show that considering measurement errors in the degradation process can significantly improve the accuracy of real time RUL prediction.
基金the National Natural Science Foundation of China(11871185)Zhejiang Provincial Natural Science Foundation of China(LY18A010010).
文摘We investigate an optimal harvesting problem for age-structured species,in which elder individuals are more competitive than younger ones,and the population is modeled by a highly nonlinear integro-partial differential equation with a global feedback boundary condition.The existence of optimal strategies is established by means of compactness and maximizing sequences,and the maximum principle obtained via an adjoint system,tangent-normal cones and a new continuity result.In addition,some numerical experiments are presented to show the effects of the price function and younger's weight on the optimal profits.
基金financially supported by the National Key R&D Program(No.2018YFC1505402)the Key Research and Development Program of Sichuan Province(No.2023YFS0435)+1 种基金the State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Independent Research Project(No.SKLGP2014Z004)the Science and Technology Innovation Fund of Sichuan Earthquake Agency(No.201901)。
文摘The Ms8.0 Wenchuan earthquake of 2008 dramatically changed the terrain surface and caused long-term increases in the scale and frequency of landslides and debris flows.The changing trend of landslides in the earthquake-affected area over the decade since the earthquake remains largely unknown.In this study,we were able to address this issue using supervised classification methods and multitemporal remote sensing images to study landslide evolution in the worst-affected area(Mianyuan River Basin)over a period of ten years.Satellite images were processed using the maximum likelihood method and random forest algorithm to automatically map landslide occurrence from 2007 to 2018.The principal findings are as follows:(1)when compared with visual image analysis,the random forest algorithm had a good average accuracy rate of 87%for landslide identification;(2)postevent landslide occurrence has generally decreased with time,but heavy monsoonal seasons have caused temporary spikes in activity;and(3)the postearthquake landslide activity in the Mianyuan River Basin can be divided into a strong activity period(2008 to 2011),medium activity period(2012 to 2016),and weak activity period(post 2017).Landslide activity remains above the prequake level,with damaging events being rare but continuing to occur.Long-term remote sensing and on-site monitoring are required to understand the evolution of landslide activity after strong earthquakes.
基金Supported by Key Project for Undergraduate Teaching Reform and Quality Enhancement Research Plan in Ordinary Colleges and Universities in Tianjin (A231005505)。
文摘A new method based on the maximum entropy principle for reconstructing the parton distribution function(PDF)from moments is proposed.Unlike traditional methods,the new method does not require any artificial assumptions.For the case of moments with errors,we introduce Gaussian functions to soften the constraints of moments.Through a series of tests,the effectiveness and reconstruction efficiency of this new method are evaluated comprehensively,demonstrating that this method is reasonable and can achieve high-quality reconstruction with at least the first six moments as input.Finally,we select a set of lattice quantum chromodynamics(QCD)results regarding moments as input and provide reasonable reconstruction results for the pion.