采用参数化等间距点焊式沉积策略,以高能微弧火花数控化沉积工艺在45钢上制备出了Al Co Cr Fe Ni高熵合金多层涂层.通过SEM和XRD研究了Al Co Cr Fe Ni高熵合金涂层表面形貌及相组成.以层数为变量,研究了电极长度消耗规律和电极/工件质...采用参数化等间距点焊式沉积策略,以高能微弧火花数控化沉积工艺在45钢上制备出了Al Co Cr Fe Ni高熵合金多层涂层.通过SEM和XRD研究了Al Co Cr Fe Ni高熵合金涂层表面形貌及相组成.以层数为变量,研究了电极长度消耗规律和电极/工件质量过渡规律,并通过Bézier曲线拟合出电极长度消耗曲线、阳极质量损失曲线、和阴极质量增加曲线.电极长度消耗规律和质量过渡规律为实现多层连续不间断沉积和涂层显微结构的精确控制奠定基础.高能微弧火花数控化沉积工艺为功能涂层的制备提供了新方法.展开更多
AIM: To identify factors associated with the age at onset of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS: Five hundred and fifty-six consecutive patients positive for HCV antibody and treat...AIM: To identify factors associated with the age at onset of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS: Five hundred and fifty-six consecutive patients positive for HCV antibody and treatment-nafive HCC diagnosed between 1995 and 2004 were analyzed. Patients were classified into three groups according to age at HCC onset: < 60 years (n = 79), 60-79 years (n = 439), or ≥ 80 years (n = 38). Differences among groups in terms of sex, body mass index (BMI), lifestyle characteristics, and liver function were assessed. Factors associated with HCC onset in patients < 60 or ≥ 80 years were analyzed by logistic regression analysis. RESULTS: Significant differences emerged for sex, BMI, degree of smoking and alcohol consumption, mean bilirubin, alanine aminotransferase (ALT), and γ-glutamyl transpeptidase (GGT) levels, prothrombin activity, and platelet counts. The mean BMI values of male patients > 60 years old were lower and mean BMI values of female patients < 60 years old were higher than those of the general Japanese population. BMI > 25 kg/m2 [hazard ratio (HR), 1.8, P = 0.045], excessive alcohol consumption (HR, 2.5, P = 0.024), male sex (HR, 3.6, P = 0.002), and GGT levels > 50 IU/L (HR, 2.4, P = 0.014) were independently associated with HCC onset in patients < 60 years. Low ALT level was the only factor associated with HCC onset in patients aged ≥ 80 years. CONCLUSION: Increased BMI is associated with increased risk for early HCC development in HCV-infected patients. Achieving recommended BMI and reducing alcohol intake could help prevent hepatic carcinogenesis.展开更多
文摘采用参数化等间距点焊式沉积策略,以高能微弧火花数控化沉积工艺在45钢上制备出了Al Co Cr Fe Ni高熵合金多层涂层.通过SEM和XRD研究了Al Co Cr Fe Ni高熵合金涂层表面形貌及相组成.以层数为变量,研究了电极长度消耗规律和电极/工件质量过渡规律,并通过Bézier曲线拟合出电极长度消耗曲线、阳极质量损失曲线、和阴极质量增加曲线.电极长度消耗规律和质量过渡规律为实现多层连续不间断沉积和涂层显微结构的精确控制奠定基础.高能微弧火花数控化沉积工艺为功能涂层的制备提供了新方法.
文摘AIM: To identify factors associated with the age at onset of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS: Five hundred and fifty-six consecutive patients positive for HCV antibody and treatment-nafive HCC diagnosed between 1995 and 2004 were analyzed. Patients were classified into three groups according to age at HCC onset: < 60 years (n = 79), 60-79 years (n = 439), or ≥ 80 years (n = 38). Differences among groups in terms of sex, body mass index (BMI), lifestyle characteristics, and liver function were assessed. Factors associated with HCC onset in patients < 60 or ≥ 80 years were analyzed by logistic regression analysis. RESULTS: Significant differences emerged for sex, BMI, degree of smoking and alcohol consumption, mean bilirubin, alanine aminotransferase (ALT), and γ-glutamyl transpeptidase (GGT) levels, prothrombin activity, and platelet counts. The mean BMI values of male patients > 60 years old were lower and mean BMI values of female patients < 60 years old were higher than those of the general Japanese population. BMI > 25 kg/m2 [hazard ratio (HR), 1.8, P = 0.045], excessive alcohol consumption (HR, 2.5, P = 0.024), male sex (HR, 3.6, P = 0.002), and GGT levels > 50 IU/L (HR, 2.4, P = 0.014) were independently associated with HCC onset in patients < 60 years. Low ALT level was the only factor associated with HCC onset in patients aged ≥ 80 years. CONCLUSION: Increased BMI is associated with increased risk for early HCC development in HCV-infected patients. Achieving recommended BMI and reducing alcohol intake could help prevent hepatic carcinogenesis.
