Background:Reinforcing-reducing manipulations are a crucial part of acupuncture therapy.The reinforcing manipulation with heat sensation(RMHS) and the reducing manipulation by inducing cool sensation(RMCS) are two rep...Background:Reinforcing-reducing manipulations are a crucial part of acupuncture therapy.The reinforcing manipulation with heat sensation(RMHS) and the reducing manipulation by inducing cool sensation(RMCS) are two representative methods of reinforcing-reducing manipulations.This trial aims to investigate the characteristic of cerebral responses to these two typical acupuncture manipulations.Methods:A total of 35 healthy participants will be included and receive acupuncture stimulation with RMHS and RMCS in a random order.The psychology,cognition,and body constitution of participants will be measured by the Self-rating Anxiety Scale(SAS),the Self-rating Depression Scale(SDS),the mindful attention awareness scale(MAAS),the Constitution in Chinese Medicine Questionnaire(CCMQ),and the needle sensation will be evaluated after each acupuncture stimulation immediately.The cerebral activity changes elicited by RMHS and RMCS will be detected by functional near-infrared spectroscopy(fNIRS)and analyzed with the general linear model-based activation and the channel-to-channel functional connectivity.Discussion:This trial will investigate the cerebral response induced by RMHS and RMCS by real-time fNIRS,so as to map the characteristics of the central responses’ patterns to these two manipulations and preliminarily explore the mechanism of traditional acupuncture manipulations.展开更多
Droplet manipulation on an open surface has great potential in chemical analysis and biomedicine engineering.However,most of the reported platforms designed for the manipulation of water droplets cannot thoroughly sol...Droplet manipulation on an open surface has great potential in chemical analysis and biomedicine engineering.However,most of the reported platforms designed for the manipulation of water droplets cannot thoroughly solve the problem of droplet evaporation.Herein,we report a shape-reconfigurable micropillar array chip for the manipulation of water droplets,oil droplets and water-in-oil droplets.Water-in-oil droplets provide an enclosed space for water droplets,preventing the evaporation in an open environment.Perfluoropolyether coated on the surface of the chip effectively reduces the droplet movement resistance.The micropillar array chip has light and magnetic dual-response due to the Fe3O4 nanoparticles and the reduced iron powder mixed in the shape-memory polymer.The micropillars irradiated by a near-infrared laser bend under the magnetic force,while the unirradiated micropillars still keep their original shape.In the absence of a magnetic field,when the micropillars in a temporary shape are irradiated by the near-infrared laser to the transition temperature,the micropillars return to their initial shape.In this process,the surface morphology gradient caused by the deformation of the micropillars and the surface tension gradient caused by the temperature change jointly produce the driving force of droplet movement.展开更多
The aerodynamic model of propeller,wing,fuselage and vertical tail are established for the tilt quad rotor(TQR)with partial tilt-wing,and then the flight dynamic model is established.Based on the six-degree-of-freedom...The aerodynamic model of propeller,wing,fuselage and vertical tail are established for the tilt quad rotor(TQR)with partial tilt-wing,and then the flight dynamic model is established.Based on the six-degree-of-freedom equation and the small disturbance linearization assumption,the trimming and stability of the tilt quad rotor with partial tilt-wing and the tilt quad rotor without tilt-wing are analyzed.The results show that in the hovering state,due to the existence of tilt-wing,the propeller wake reduces the downwash on the wing,thereby reducing the vertical weight gain of the aircraft.It is beneficial to increase the endurance time and improve the endurance performance.The transition corridor of the TQR with tilt-wing is narrower than that of the TQR without tilt-wing,but the transition corridor of TQR with tilt-wing still has a large space for design.Furthermore,the stability analysis shows that the Dutch roll damping ratio is larger,and in other modes the aircraft has a certain stability.The manipulation response analysis shows that in the transition mode the lateral-directional coupling is strong.展开更多
Tank sloshing in ship cargo is excited by ship motions, which induces impact load on tank wall and then affects the ship motion. Wave forces acting on ship hull and the retardation function are solved by using three-d...Tank sloshing in ship cargo is excited by ship motions, which induces impact load on tank wall and then affects the ship motion. Wave forces acting on ship hull and the retardation function are solved by using three-dimensional frequency domain theory and an impulse response function method based on the potential flow theory, and global ship motion is examined coupling with nonlinear tank sloshing which is simulated by viscous flow theory. Based on the open source Computational Fluid Dynamics (CFD) development platform Open Field Operation and Manipulation (OpenFOAM), numerical calculation of ship motion coupled with tank sloshing is achieved and the corresponding numerical simulation and validation are carried out. With this method, the interactions of wave, ship body and tank sloshing are completely taken into consideration. This method has quite high efficiency for it takes advantage of potential flow theory for outer flow field and viscous flow theory for inside tank sloshing respectively. The numerical and experimental results of the ship motion agree well with each other.展开更多
基金supported by grants from the National Natural Science Foundation of China (NO.81973960)the Sichuan Scientific and Technological Innovation Team (No.2019JDTD0011)。
文摘Background:Reinforcing-reducing manipulations are a crucial part of acupuncture therapy.The reinforcing manipulation with heat sensation(RMHS) and the reducing manipulation by inducing cool sensation(RMCS) are two representative methods of reinforcing-reducing manipulations.This trial aims to investigate the characteristic of cerebral responses to these two typical acupuncture manipulations.Methods:A total of 35 healthy participants will be included and receive acupuncture stimulation with RMHS and RMCS in a random order.The psychology,cognition,and body constitution of participants will be measured by the Self-rating Anxiety Scale(SAS),the Self-rating Depression Scale(SDS),the mindful attention awareness scale(MAAS),the Constitution in Chinese Medicine Questionnaire(CCMQ),and the needle sensation will be evaluated after each acupuncture stimulation immediately.The cerebral activity changes elicited by RMHS and RMCS will be detected by functional near-infrared spectroscopy(fNIRS)and analyzed with the general linear model-based activation and the channel-to-channel functional connectivity.Discussion:This trial will investigate the cerebral response induced by RMHS and RMCS by real-time fNIRS,so as to map the characteristics of the central responses’ patterns to these two manipulations and preliminarily explore the mechanism of traditional acupuncture manipulations.
基金the Natural Science Foundation of China(No.21874015)the Fundamental Research Funds for the Central Universities(No.N2005024).
文摘Droplet manipulation on an open surface has great potential in chemical analysis and biomedicine engineering.However,most of the reported platforms designed for the manipulation of water droplets cannot thoroughly solve the problem of droplet evaporation.Herein,we report a shape-reconfigurable micropillar array chip for the manipulation of water droplets,oil droplets and water-in-oil droplets.Water-in-oil droplets provide an enclosed space for water droplets,preventing the evaporation in an open environment.Perfluoropolyether coated on the surface of the chip effectively reduces the droplet movement resistance.The micropillar array chip has light and magnetic dual-response due to the Fe3O4 nanoparticles and the reduced iron powder mixed in the shape-memory polymer.The micropillars irradiated by a near-infrared laser bend under the magnetic force,while the unirradiated micropillars still keep their original shape.In the absence of a magnetic field,when the micropillars in a temporary shape are irradiated by the near-infrared laser to the transition temperature,the micropillars return to their initial shape.In this process,the surface morphology gradient caused by the deformation of the micropillars and the surface tension gradient caused by the temperature change jointly produce the driving force of droplet movement.
基金supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)
文摘The aerodynamic model of propeller,wing,fuselage and vertical tail are established for the tilt quad rotor(TQR)with partial tilt-wing,and then the flight dynamic model is established.Based on the six-degree-of-freedom equation and the small disturbance linearization assumption,the trimming and stability of the tilt quad rotor with partial tilt-wing and the tilt quad rotor without tilt-wing are analyzed.The results show that in the hovering state,due to the existence of tilt-wing,the propeller wake reduces the downwash on the wing,thereby reducing the vertical weight gain of the aircraft.It is beneficial to increase the endurance time and improve the endurance performance.The transition corridor of the TQR with tilt-wing is narrower than that of the TQR without tilt-wing,but the transition corridor of TQR with tilt-wing still has a large space for design.Furthermore,the stability analysis shows that the Dutch roll damping ratio is larger,and in other modes the aircraft has a certain stability.The manipulation response analysis shows that in the transition mode the lateral-directional coupling is strong.
文摘Tank sloshing in ship cargo is excited by ship motions, which induces impact load on tank wall and then affects the ship motion. Wave forces acting on ship hull and the retardation function are solved by using three-dimensional frequency domain theory and an impulse response function method based on the potential flow theory, and global ship motion is examined coupling with nonlinear tank sloshing which is simulated by viscous flow theory. Based on the open source Computational Fluid Dynamics (CFD) development platform Open Field Operation and Manipulation (OpenFOAM), numerical calculation of ship motion coupled with tank sloshing is achieved and the corresponding numerical simulation and validation are carried out. With this method, the interactions of wave, ship body and tank sloshing are completely taken into consideration. This method has quite high efficiency for it takes advantage of potential flow theory for outer flow field and viscous flow theory for inside tank sloshing respectively. The numerical and experimental results of the ship motion agree well with each other.