在大视场红外光学系统中,基于普通红外光学材料实现的光学被动无热化系统存在透镜数量多且不易实现轻量化、小型化的技术问题。为解决这个问题,采用硫系玻璃与常用红外材料组合来实现光学被动无热化,并设计了一种视场为40°×32...在大视场红外光学系统中,基于普通红外光学材料实现的光学被动无热化系统存在透镜数量多且不易实现轻量化、小型化的技术问题。为解决这个问题,采用硫系玻璃与常用红外材料组合来实现光学被动无热化,并设计了一种视场为40°×32.5°、工作波段为8~12 m、F数为1.0、工作温度范围为-55℃~+70℃的小型化非制冷红外成像光学系统。设计结果表明,该系统结构简单紧凑、成像性能良好,在空间频率421p/mm处的调制传递函数(Modulation Transfer Function,MTF)值大于0.3,能够满足实际工程应用的需求。展开更多
Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously anal...Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.展开更多
Large field-of-view（FoV） three-dimensional（3 D） photon-counting imaging is demonstrated with a single-pixel single-photon detector based on a Geiger-mode Si-avalanche photodiode. By removing the collecting lens（C...Large field-of-view（FoV） three-dimensional（3 D） photon-counting imaging is demonstrated with a single-pixel single-photon detector based on a Geiger-mode Si-avalanche photodiode. By removing the collecting lens（CL）before the detector, the FoV is expanded to ±10°. Thanks to the high detection efficiency, the signal-to-noise ratio of the imaging system is as high as 7.8 dB even without the CL when the average output laser pulse energy is about 0.45 pJ/pulse for imaging the targets at a distance of 5 m. A 3 D image overlaid with the reflectivity data is obtained according to the photon-counting time-of-flight measurement and the return photon intensity.展开更多
In this paper a millimeter-wave （MMW） squint indirect holographic method is presented, which is suitable for imaging with a large field-of-view. The proposed system employs the squint operation mode to remove the ba...In this paper a millimeter-wave （MMW） squint indirect holographic method is presented, which is suitable for imaging with a large field-of-view. The proposed system employs the squint operation mode to remove the background and twin- image interferences, which achieves a similar effect to off-axis holography but leaves out the large-aperture quasi-optical component. The translational scanning manner enables a large field of view and ensures the image uniformity, which is difficult to realize in off-axis holography. In addition, a corresponding imaging algorithm for the presented scheme is developed to reconstruct the image from the recorded hologram. Some imaging results on typical objects, obtained with electromagnetic simulation, demonstrate good performance of the imaging scheme and validate the effectiveness of the image reconstruction algorithm.展开更多
文摘在大视场红外光学系统中,基于普通红外光学材料实现的光学被动无热化系统存在透镜数量多且不易实现轻量化、小型化的技术问题。为解决这个问题,采用硫系玻璃与常用红外材料组合来实现光学被动无热化,并设计了一种视场为40°×32.5°、工作波段为8~12 m、F数为1.0、工作温度范围为-55℃~+70℃的小型化非制冷红外成像光学系统。设计结果表明,该系统结构简单紧凑、成像性能良好,在空间频率421p/mm处的调制传递函数(Modulation Transfer Function,MTF)值大于0.3,能够满足实际工程应用的需求。
基金supported by National Key R&D Program of China(grant no.2022YFC2404201)the Chinese Academy of Sciences Project for Young Scientists in Basic Research(grant no.YSBR067).
文摘Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 mm.This restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain areas.In addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in vivo.Here we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 nm.We achieved a resolution of 0.74μm in fluorescent beads imaging.The versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging system.This mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11774095,11722431 and 11621404the Shanghai Basic Research Project under Grant No 18JC1412200+2 种基金the National Key R&D Program of China under Grant No2016YFB0400904the Program of Introducing Talents of Discipline to Universities under Grant No B12024the Shanghai International Cooperation Project under Grant No 16520710600
文摘Large field-of-view（FoV） three-dimensional（3 D） photon-counting imaging is demonstrated with a single-pixel single-photon detector based on a Geiger-mode Si-avalanche photodiode. By removing the collecting lens（CL）before the detector, the FoV is expanded to ±10°. Thanks to the high detection efficiency, the signal-to-noise ratio of the imaging system is as high as 7.8 dB even without the CL when the average output laser pulse energy is about 0.45 pJ/pulse for imaging the targets at a distance of 5 m. A 3 D image overlaid with the reflectivity data is obtained according to the photon-counting time-of-flight measurement and the return photon intensity.
文摘利用普通红外光学材料实现的大视场光学被动无热化系统应用于当前新型高分辨率、大面阵红外探测器时存在透镜数量多,不易实现轻量化、小型化的技术问题。为此,引入了低折射率温度系数的硫系玻璃,并设计了一种工作波段为8~12 μm、视场为40°×32.5°、F数为1.0且适配1280×1024探测器的光学被动无热化成像光学系统。设计结果表明,在-55℃~70℃的工作温度范围内,探测器特征频率42 1p/mm处的光学传递函数(Modulation Transfer Function,MTF)值均大于0.35,系统成像性能良好,能够满足实际工程应用需求。
基金Project supported by the National Natural Science Foundation of China (Grant Nos.11174280,60990323,and 60990320)the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No.YYYJ-1123)
文摘In this paper a millimeter-wave （MMW） squint indirect holographic method is presented, which is suitable for imaging with a large field-of-view. The proposed system employs the squint operation mode to remove the background and twin- image interferences, which achieves a similar effect to off-axis holography but leaves out the large-aperture quasi-optical component. The translational scanning manner enables a large field of view and ensures the image uniformity, which is difficult to realize in off-axis holography. In addition, a corresponding imaging algorithm for the presented scheme is developed to reconstruct the image from the recorded hologram. Some imaging results on typical objects, obtained with electromagnetic simulation, demonstrate good performance of the imaging scheme and validate the effectiveness of the image reconstruction algorithm.
基金国家自然科学基金(81930048)国家自然科学基金优秀青年科学基金(62105353)+3 种基金广东省自然科学基金(2019A1515011374,2019BT02X105,2020B121201010)香港Research Grant Council(15217721,C7074-21GF,R5029-19)香港创新科技署深港联合创新圈项目(GHP/043/19 SZ)香港创新科技署粤港联合创新圈项目(GHP/044/19GD)。
