AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pan...AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis.展开更多
Songke Well No.2,one of the main part of the scientific drilling project in Songliao Basin,which was drilled 7018 m and acquired the part of cores continuously from the Low Cretaceous to the Carboniferous and the Perm...Songke Well No.2,one of the main part of the scientific drilling project in Songliao Basin,which was drilled 7018 m and acquired the part of cores continuously from the Low Cretaceous to the Carboniferous and the Permian from the 2843 m deep,can be considered as the deepest continental drilling project in Asia.Aiming at the features of longer well sections,larger diameters and multiple spud-ins for coring of Songke Well No.2,this project broke through the "coring in small diameter and reaming in large diameter"spud-in drilling-completion procedures which are always used in large-diameter-well coring for continental scientific drilling projects in domestic and overseas and the drilling method of short-singlecylinder roundtrip footage.At the same time,"coring in the same diameter and completing drilling at one single diameter"was achieved at all φ311 mm and φ216 mm coring sections of more than one thousand meters long,high-efficient operation with "drilling long footage with drill tools combined in multicylinders"was achieved at deep coring section.Four world drilling records were created which include more than a thousand meters continuous coring at φ311 mm,and the footage per roundtrip footage at φ311 mm,φ216 mm and φ152 mm is all more than 30 m,all of these breakthroughs reduced at least 300 days for this project;moreover,considering the characteristics of formations that the geothermal gradient is high in the drilled sections and the inside-well temperature is over 240℃ after drilling completion,a formate-polymer water-based mud system was developed by compounding attapulgite and sodium bentonite and by adding independently developed high-temperature stabilizer,which can provide critical technical support for successful well completion at 7018 m in the super-high-temperature environment It is the first time that the water-based mud is operated at the working temperature higher than 240℃ in China;Besides,considering the high-quality requirement on cores imposed by the project,the method "mechanical cor展开更多
Large eddy simulations(LES) were performed to study the non-reacting flow fields of a Cambridge swirl burner. The dynamic Smagorinsky eddy viscosity model is used as the sub-grid scale turbulence model. Comparisons of...Large eddy simulations(LES) were performed to study the non-reacting flow fields of a Cambridge swirl burner. The dynamic Smagorinsky eddy viscosity model is used as the sub-grid scale turbulence model. Comparisons of experimental data show that the LES results are capable of predicting mean and root-mean-square velocity profiles. The LES results show that the annular swirling flow has a minor impact on the formation of the bluff-body recirculation zone. The vortex structures near the shear layers, visualized by the iso-surface of Q-criterion, display ring structures in non-swirling flow and helical structures in swirling flow near the burner exit. Spectral analysis was employed to predict the occurrence of flow oscillations induced by vortex shedding and precessing vortex core(PVC). In order to extract accurately the unsteady large-scale structures in swirling flow, a three-dimensional proper orthogonal decomposition(POD) method was developed to reconstruct turbulent fluctuating velocity fields. POD analysis reveals that flow fields contain co-existing helical and toroidal shaped coherent structures. The helical structure associated with the PVC is the most energetic dynamic flow structure. The latter toroidal structure associated with vortex shedding has lower energy content which indicates that it is a secondary structure.展开更多
文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis.
文摘Songke Well No.2,one of the main part of the scientific drilling project in Songliao Basin,which was drilled 7018 m and acquired the part of cores continuously from the Low Cretaceous to the Carboniferous and the Permian from the 2843 m deep,can be considered as the deepest continental drilling project in Asia.Aiming at the features of longer well sections,larger diameters and multiple spud-ins for coring of Songke Well No.2,this project broke through the "coring in small diameter and reaming in large diameter"spud-in drilling-completion procedures which are always used in large-diameter-well coring for continental scientific drilling projects in domestic and overseas and the drilling method of short-singlecylinder roundtrip footage.At the same time,"coring in the same diameter and completing drilling at one single diameter"was achieved at all φ311 mm and φ216 mm coring sections of more than one thousand meters long,high-efficient operation with "drilling long footage with drill tools combined in multicylinders"was achieved at deep coring section.Four world drilling records were created which include more than a thousand meters continuous coring at φ311 mm,and the footage per roundtrip footage at φ311 mm,φ216 mm and φ152 mm is all more than 30 m,all of these breakthroughs reduced at least 300 days for this project;moreover,considering the characteristics of formations that the geothermal gradient is high in the drilled sections and the inside-well temperature is over 240℃ after drilling completion,a formate-polymer water-based mud system was developed by compounding attapulgite and sodium bentonite and by adding independently developed high-temperature stabilizer,which can provide critical technical support for successful well completion at 7018 m in the super-high-temperature environment It is the first time that the water-based mud is operated at the working temperature higher than 240℃ in China;Besides,considering the high-quality requirement on cores imposed by the project,the method "mechanical cor
基金supported by the National Natural Science Foundation of China(Grant Nos.51176178&91441117)the Key Program of National Natural Science Foundation of China(Grant No.50936005)
文摘Large eddy simulations(LES) were performed to study the non-reacting flow fields of a Cambridge swirl burner. The dynamic Smagorinsky eddy viscosity model is used as the sub-grid scale turbulence model. Comparisons of experimental data show that the LES results are capable of predicting mean and root-mean-square velocity profiles. The LES results show that the annular swirling flow has a minor impact on the formation of the bluff-body recirculation zone. The vortex structures near the shear layers, visualized by the iso-surface of Q-criterion, display ring structures in non-swirling flow and helical structures in swirling flow near the burner exit. Spectral analysis was employed to predict the occurrence of flow oscillations induced by vortex shedding and precessing vortex core(PVC). In order to extract accurately the unsteady large-scale structures in swirling flow, a three-dimensional proper orthogonal decomposition(POD) method was developed to reconstruct turbulent fluctuating velocity fields. POD analysis reveals that flow fields contain co-existing helical and toroidal shaped coherent structures. The helical structure associated with the PVC is the most energetic dynamic flow structure. The latter toroidal structure associated with vortex shedding has lower energy content which indicates that it is a secondary structure.
