评审专家遴选是技术评审中的关键环节。鉴于颠覆性技术专家预判平台预判系统对时效性和智能型的要求,专家遴选对预判结果具有决定性影响。通过学术专长匹配和专业遴选来选择符合要求的专家,可以降低成本,提高推荐效率与准确度,完成颠覆...评审专家遴选是技术评审中的关键环节。鉴于颠覆性技术专家预判平台预判系统对时效性和智能型的要求,专家遴选对预判结果具有决定性影响。通过学术专长匹配和专业遴选来选择符合要求的专家,可以降低成本,提高推荐效率与准确度,完成颠覆性技术的预测任务。基于学术网络表示学习的方法既可以避免大量特征工程,又可以方便不同类型的特征进行融合。利用异质网络表示学习方法和标签排序的学术专长画像方法构建专家库,并使用融合专家综合评价指标特征的匹配方法对待预判的颠覆性技术和专家专长进行匹配,为专家遴选提供一份专业背景匹配的候选专家列表。这种方法在Academic Social Network数据集上进行模拟实验。实验结果表明,这种方法能提升项目评审专家学术专长匹配,在加入综合指标特征后,专家的综合指标特征能有效地反馈到实验结果中,从而提高评审系统的时效性和智能性。展开更多
The penetration behavior of topical substances in the skin not only relates to the transdermal delivery efficiency but also involves the safety and therapeutic effect of topical products,such as sunscreen and hair gro...The penetration behavior of topical substances in the skin not only relates to the transdermal delivery efficiency but also involves the safety and therapeutic effect of topical products,such as sunscreen and hair growth products.Researchers have tried to illustrate the transdermal process with diversified theories and technologies.Directly observing the distribution of topical substances on skin by characteristic imaging is the most convincing approach.Unfortunately,fluorescence labeling imaging,which is commonly used in biochemical research,is limited for transdermal research for most topical substances with a molecular mass less than 500 Da.Label-free imaging technologies possess the advantages of not requiring any macromolecular dyes,no tissue destruction and an extensive substance detection capability,which has enabled rapid development of such technologies in recent years and their introduction to biological tissue analysis,such as skin samples.Through the specific identification of topical substances and endogenous tissue components,label-free imaging technologies can provide abundant tissue distribution information,enrich theoretical and practical guidance for transdermal drug delivery systems.In this review,we expound the mechanisms and applications of the most popular label-free imaging technologies in transdermal research at present,compare their advantages and disadvantages,and forecast development prospects.展开更多
Mountain farming provides high-quality food products due to the peculiar characteristics of the raw materials combined with traditional processing conditions. However, these products and their intrinsic characteristic...Mountain farming provides high-quality food products due to the peculiar characteristics of the raw materials combined with traditional processing conditions. However, these products and their intrinsic characteristics are not clearly recognized by consumers on the market. Nowadays, Protected Designation of Origin(PDO), Protected Geographical Indication(PGI) and Traditional Specialities Guaranteed(TSG) certifications include products originating in mountain areas, even if a large part of mountain foodstuff is not protected by these certifications and foods not made in mountain areas are often labeled as ―mountain food products‖. For this reason, the European Union has set a specific Regulation in 2012 to recognize and protect mountain food and to make the consumers safer about the origin information. The objective of this paper is twofold: firstly, it presents the recent aspects related to European legislation of mountain food product; secondly, it aims at reviewing the main features of nutritional quality and technology of dairy and meat products, as the most widespread mountain food products, and the main protocols used to evaluate the authenticity of these food products. The promotion of mountain food product through a specific label and the use of tracing methods, which are able to verify the authenticity of the origin of these products, may play a pivotal role in increasing the consumer‘s loyalty towards these products and could be a way to boost a sustainable development of these economically marginal rural areas. However, the analytical protocols developed so far(stable isotopes, macro and microelements, radionuclides, spectroscopic, molecular techniques, volatile substances profile, terpenes) are in many cases still at the experimental level due to the extreme variability of the mountain origin of the products to be tested.展开更多
文摘评审专家遴选是技术评审中的关键环节。鉴于颠覆性技术专家预判平台预判系统对时效性和智能型的要求,专家遴选对预判结果具有决定性影响。通过学术专长匹配和专业遴选来选择符合要求的专家,可以降低成本,提高推荐效率与准确度,完成颠覆性技术的预测任务。基于学术网络表示学习的方法既可以避免大量特征工程,又可以方便不同类型的特征进行融合。利用异质网络表示学习方法和标签排序的学术专长画像方法构建专家库,并使用融合专家综合评价指标特征的匹配方法对待预判的颠覆性技术和专家专长进行匹配,为专家遴选提供一份专业背景匹配的候选专家列表。这种方法在Academic Social Network数据集上进行模拟实验。实验结果表明,这种方法能提升项目评审专家学术专长匹配,在加入综合指标特征后,专家的综合指标特征能有效地反馈到实验结果中,从而提高评审系统的时效性和智能性。
文摘The penetration behavior of topical substances in the skin not only relates to the transdermal delivery efficiency but also involves the safety and therapeutic effect of topical products,such as sunscreen and hair growth products.Researchers have tried to illustrate the transdermal process with diversified theories and technologies.Directly observing the distribution of topical substances on skin by characteristic imaging is the most convincing approach.Unfortunately,fluorescence labeling imaging,which is commonly used in biochemical research,is limited for transdermal research for most topical substances with a molecular mass less than 500 Da.Label-free imaging technologies possess the advantages of not requiring any macromolecular dyes,no tissue destruction and an extensive substance detection capability,which has enabled rapid development of such technologies in recent years and their introduction to biological tissue analysis,such as skin samples.Through the specific identification of topical substances and endogenous tissue components,label-free imaging technologies can provide abundant tissue distribution information,enrich theoretical and practical guidance for transdermal drug delivery systems.In this review,we expound the mechanisms and applications of the most popular label-free imaging technologies in transdermal research at present,compare their advantages and disadvantages,and forecast development prospects.
基金supported with funding from the Department of AgriculturalFood and Environmental Sciences(D3A)–Polytechnic University of Marche+1 种基金the Faculty of Science and Technology,Free University of Bolzanothe Chemical Safety Department,the Experimental Station for the Food Preserving Industry(SSICA)
文摘Mountain farming provides high-quality food products due to the peculiar characteristics of the raw materials combined with traditional processing conditions. However, these products and their intrinsic characteristics are not clearly recognized by consumers on the market. Nowadays, Protected Designation of Origin(PDO), Protected Geographical Indication(PGI) and Traditional Specialities Guaranteed(TSG) certifications include products originating in mountain areas, even if a large part of mountain foodstuff is not protected by these certifications and foods not made in mountain areas are often labeled as ―mountain food products‖. For this reason, the European Union has set a specific Regulation in 2012 to recognize and protect mountain food and to make the consumers safer about the origin information. The objective of this paper is twofold: firstly, it presents the recent aspects related to European legislation of mountain food product; secondly, it aims at reviewing the main features of nutritional quality and technology of dairy and meat products, as the most widespread mountain food products, and the main protocols used to evaluate the authenticity of these food products. The promotion of mountain food product through a specific label and the use of tracing methods, which are able to verify the authenticity of the origin of these products, may play a pivotal role in increasing the consumer‘s loyalty towards these products and could be a way to boost a sustainable development of these economically marginal rural areas. However, the analytical protocols developed so far(stable isotopes, macro and microelements, radionuclides, spectroscopic, molecular techniques, volatile substances profile, terpenes) are in many cases still at the experimental level due to the extreme variability of the mountain origin of the products to be tested.
