Introduction: Thyroid pathologies are either the cause or a consequence of certain pathologies with which they interact, manifesting themselves through a polymorphic and non-specific clinic. They affect different devi...Introduction: Thyroid pathologies are either the cause or a consequence of certain pathologies with which they interact, manifesting themselves through a polymorphic and non-specific clinic. They affect different devices and/or systems, making the clinical picture more complex or even a delay in diagnosis and treatment. These latter aspects, being then multidimensional, could be preceded by a very specific patient itinerary for the diagnosis and management of cases of thyroid gland pathologies. Methods: This was a descriptive cross-sectional study whose data were collected from May 1 to October 30, 2022. It focused on patients followed for thyroid diseases at the Conakry University Hospital. The objectives were to describe the patient’s journey before their diagnosis of thyroid disease. Results: The subjects were 86.1% women with a mean age of 43.7 ± 28 years. Of the total, 67.85% had a comorbidity including diabetes and/or hypertension/heart disease. They are followed for goiters/simple nodules (22.78%), hypothyroidism (16.46%) and hyperthyroidism (60.76%). They spend at least 9 months before resorting to a healthcare facility. The general medicine services of the Conakry University Hospital are the first recourse (51.9%) of these subjects. They consult 2 to 4 times before the diagnosis is suggested. Hyperthyroidism, hypothyroidism and goiters/simple nodules spend 5.4;6.4 and 13.7 months respectively before the diagnosis is made. 31.6% were hospitalized and treated mainly for malaria (19.0%), hypertension (13.1%), salmonellosis (13.1%) and diabetes (8.3%). A third of patients used traditional therapy before being in contact with the endocrinology department by referral (73.4%). Conclusion: This study made it possible to show a pre-diagnostic pathway which has a particular character concerning patients followed for thyroid pathologies in Guinea.展开更多
Under the background of the rapid development of the air transport industry, the abnormal phenomenon of flights has become increasingly serious due to various factors such as the gradual reduction of resources, advers...Under the background of the rapid development of the air transport industry, the abnormal phenomenon of flights has become increasingly serious due to various factors such as the gradual reduction of resources, adverse climatic conditions, problems in air traffic control and mechanical failures. In order to reduce losses, it has become a major problem for airlines to use optimization algorithm to study the recovery of abnormal flights. By upgrading the passenger recovery engine, the purpose of this paper is to provide the optimal recovery scheme for passengers, so as to reduce the risk of transferring overseas flights, and thus reduce the economic loss of airlines. In this paper, the optimization model and algorithm based on network flow, combined with actual business requirements, comprehensively consider multiple optimization objectives to quickly generate passenger recovery solutions, and at the same time achieve the optimal income of airlines and the acceptance rate of passenger recovery, so as to balance the two. The practicability and effectiveness of the proposed model and algorithm are proved by some concrete examples.展开更多
The security problem of mobile agents is widely being discussed. The problem which protects mobile agents from malicious hosts is difficult to solve, because a host has access to the complete internal state of an agen...The security problem of mobile agents is widely being discussed. The problem which protects mobile agents from malicious hosts is difficult to solve, because a host has access to the complete internal state of an agent. Forward integrity in mobile agents guarantees that offers contained in a mobile agent from previously visited host can not be modified by a malicious host. Itinerary secrecy can prevent mobile agent from being passively attack. This paper proposes a new forward integrity and itinerary secrecy protocol for mobile agent. The protocol can also resist collusion truncation attack.展开更多
Pervasive developmental disorders (PDD) remain little known to populations in developing countries. In black Africa their social representations remain strongly influenced by local belief systems. The general objectiv...Pervasive developmental disorders (PDD) remain little known to populations in developing countries. In black Africa their social representations remain strongly influenced by local belief systems. The general objective of this study was to understand the perceptions and representations of Ivorian parents vis-à-vis PDD. This was a mixed (qualitative and quantitative) prospective cross-sectional study with a descriptive aim that involved a sample of 49 parents. The sampling was of the qualitative type by multiple cases with reasoned choice by saturation. Our results showed that male parents were mostly aged between 40 - 49 years (48.98%) with a higher level of education (67.34%) while mothers were mostly aged between 30 - 39 (61.22%) and a higher level (30.61%). Autistic children were negatively perceived by their parents: either as a source of psychological suffering (82.85%), or as mysterious children who sacrificed their parents (44.66%), or as “bobo” children (mute children in common Ivorian language) (16.66%) or like rude children (13.34%). The supposed origin of the disorder according to the parents was mystical-religious (60.94%);natural (25%);hereditary (6.25%). In 6.25% of cases, PDD were assumed to be of unknown or iatrogenic origin attributable to vaccination (1.56%). 75.51% of parents said that in addition to conventional medical therapies, they also used traditional therapies. The use of this therapeutic alternative would be linked to the perceptions and beliefs that feed the socio-cultural representations of our respondents.展开更多
The aspect discussed in the present paper should ont be identified strictly with the natu-ral and geogrophical arid areas in the whole China, but only referred to the seven provincesas Shaanxi, Gansu, Qinhai, Xinjiang...The aspect discussed in the present paper should ont be identified strictly with the natu-ral and geogrophical arid areas in the whole China, but only referred to the seven provincesas Shaanxi, Gansu, Qinhai, Xinjiang and Inner Mongolia. According to the real conditions of the development of tourism which was formedobjectively in the arid areas, it is necessary to consider comprehensively the influence by展开更多
<strong>Introduction:</strong> In black Africa, connectivites have been for a long time a source of diagnostic erraticity because of their clinical polymorphism. This study aims to determine the therapeuti...<strong>Introduction:</strong> In black Africa, connectivites have been for a long time a source of diagnostic erraticity because of their clinical polymorphism. This study aims to determine the therapeutic itinerary of patients followed for connectivitis in the Internal Medicine Department of the CNHU HKM of Cotonou. <strong>Methodology:</strong> This is a cross-sectional study that included patients followed for connectivitis in the HKM-Cotonou Internal Medicine Department from January 2010 to October 2018. <strong>Results:</strong> Out of 3600 patients hospitalized in the study period, 21 had connectivitis, <i>i.e.</i> a hospital frequency of 0.58%. Of the 21 patients collected, 18 met the inclusion criteria. The mean age was 40 (±11) years old and the youngest was of 21 and the oldest 58. The sex ratio was 17.9. The “Fon” ethnic group was the most represented (33.3%) and 15 (83.3%) subjects were Christians. Systemic lupus erythematosus was the most frequent connectivitis (55.6%). The average time of consultation was 38 months. Witchcraft was the most incriminating cause (78%). Ten (55.5%) patients had resorted to self-medication as their first choice of treatment, 5 (27.8%) to traditional medicine treatment and 3 (16.7%) to prayer for healing. The reasons for the first choice of treatment were satisfaction (44.4%), financial problems (27.8%), trivialization of the disease (16.7%), and advice from family and friends (11.1%). The consultation at the CNHU followed a referral from a first contact health structure (61%) or an initiative of the patient (27.8%). <strong>Conclusion:</strong> Connectivitis is a source of diagnostic error in our context. Awareness must be raised among patients for an early consultation at the first symptoms.展开更多
Introduction: The therapeutic pathway affects the patient who changes care facilities. This change is linked to factors such as financial means, geographical accessibility of care facilities, quality of care and the s...Introduction: The therapeutic pathway affects the patient who changes care facilities. This change is linked to factors such as financial means, geographical accessibility of care facilities, quality of care and the socio-cultural perception of the patient. In countries with limited resources such as Guinea, the therapeutic itinerary remains multiple and hampered by obstacles. The objective of this study was to describe the therapeutic itinerary of patients living with hepatitis B and C at the Donka National Hospital. Material and methods: This was a retrospective, descriptive study lasting 43 months (24 January 2017 - 27 August 2020);it focused on patients living with hepatitis B or C or viral cirrhosis. We collected sociodemographic, clinical and treatment history variables. The data were analysed with SPSS software version 21.0. Results: Out of 5400 patients, the proportion of viral hepatitis B or C represented 393 patients (7.3%). The mean age of our patients was 35 ± 10 years, with extremes of 16 - 77 years. The sex ratio was 2.5. Three hundred and forty-two patients (87%) had recourse to modern medicine, mostly in private facilities (50.6%). One hundred and twenty-five patients (31.8%) had received previous treatment, half of whom (57.6%) had received inappropriate treatment. The delay in treatment was long in 45% of cases. The main reasons for delaying treatment were feeling unwell in 33.3%;not knowing to consult a specialist in 29.9% and feeling that they were being treated with useful drugs in 24.3%. Conclusion: The lack of training of general practitioners on the management of viral hepatitis and the scarcity of awareness campaigns on viral hepatitis contributed to the inadequacy of the management.展开更多
晚清来华耶稣会士的论著是研究晚清社会宗教的重要文献资料。英国传教士约翰·亨利·格雷Walks in the City of Canton:with an Itinerary一书以观赏者的视角描述了晚清广州城的历史面貌,尤其是对广州城的佛寺有浓墨重彩的描述...晚清来华耶稣会士的论著是研究晚清社会宗教的重要文献资料。英国传教士约翰·亨利·格雷Walks in the City of Canton:with an Itinerary一书以观赏者的视角描述了晚清广州城的历史面貌,尤其是对广州城的佛寺有浓墨重彩的描述。不仅如实记录了佛教道场的历史传承,且重点探析了变动社会中佛门的真实转向。从中可以窥探社会经济背景与宗教文化之间的动态互动关系,进而藉此加深对晚清社会的理解。展开更多
文摘Introduction: Thyroid pathologies are either the cause or a consequence of certain pathologies with which they interact, manifesting themselves through a polymorphic and non-specific clinic. They affect different devices and/or systems, making the clinical picture more complex or even a delay in diagnosis and treatment. These latter aspects, being then multidimensional, could be preceded by a very specific patient itinerary for the diagnosis and management of cases of thyroid gland pathologies. Methods: This was a descriptive cross-sectional study whose data were collected from May 1 to October 30, 2022. It focused on patients followed for thyroid diseases at the Conakry University Hospital. The objectives were to describe the patient’s journey before their diagnosis of thyroid disease. Results: The subjects were 86.1% women with a mean age of 43.7 ± 28 years. Of the total, 67.85% had a comorbidity including diabetes and/or hypertension/heart disease. They are followed for goiters/simple nodules (22.78%), hypothyroidism (16.46%) and hyperthyroidism (60.76%). They spend at least 9 months before resorting to a healthcare facility. The general medicine services of the Conakry University Hospital are the first recourse (51.9%) of these subjects. They consult 2 to 4 times before the diagnosis is suggested. Hyperthyroidism, hypothyroidism and goiters/simple nodules spend 5.4;6.4 and 13.7 months respectively before the diagnosis is made. 31.6% were hospitalized and treated mainly for malaria (19.0%), hypertension (13.1%), salmonellosis (13.1%) and diabetes (8.3%). A third of patients used traditional therapy before being in contact with the endocrinology department by referral (73.4%). Conclusion: This study made it possible to show a pre-diagnostic pathway which has a particular character concerning patients followed for thyroid pathologies in Guinea.
文摘Under the background of the rapid development of the air transport industry, the abnormal phenomenon of flights has become increasingly serious due to various factors such as the gradual reduction of resources, adverse climatic conditions, problems in air traffic control and mechanical failures. In order to reduce losses, it has become a major problem for airlines to use optimization algorithm to study the recovery of abnormal flights. By upgrading the passenger recovery engine, the purpose of this paper is to provide the optimal recovery scheme for passengers, so as to reduce the risk of transferring overseas flights, and thus reduce the economic loss of airlines. In this paper, the optimization model and algorithm based on network flow, combined with actual business requirements, comprehensively consider multiple optimization objectives to quickly generate passenger recovery solutions, and at the same time achieve the optimal income of airlines and the acceptance rate of passenger recovery, so as to balance the two. The practicability and effectiveness of the proposed model and algorithm are proved by some concrete examples.
基金Supported by the National Natural Science Foun-dation of China (60373087 ,60473023 ,90104005)
文摘The security problem of mobile agents is widely being discussed. The problem which protects mobile agents from malicious hosts is difficult to solve, because a host has access to the complete internal state of an agent. Forward integrity in mobile agents guarantees that offers contained in a mobile agent from previously visited host can not be modified by a malicious host. Itinerary secrecy can prevent mobile agent from being passively attack. This paper proposes a new forward integrity and itinerary secrecy protocol for mobile agent. The protocol can also resist collusion truncation attack.
文摘Pervasive developmental disorders (PDD) remain little known to populations in developing countries. In black Africa their social representations remain strongly influenced by local belief systems. The general objective of this study was to understand the perceptions and representations of Ivorian parents vis-à-vis PDD. This was a mixed (qualitative and quantitative) prospective cross-sectional study with a descriptive aim that involved a sample of 49 parents. The sampling was of the qualitative type by multiple cases with reasoned choice by saturation. Our results showed that male parents were mostly aged between 40 - 49 years (48.98%) with a higher level of education (67.34%) while mothers were mostly aged between 30 - 39 (61.22%) and a higher level (30.61%). Autistic children were negatively perceived by their parents: either as a source of psychological suffering (82.85%), or as mysterious children who sacrificed their parents (44.66%), or as “bobo” children (mute children in common Ivorian language) (16.66%) or like rude children (13.34%). The supposed origin of the disorder according to the parents was mystical-religious (60.94%);natural (25%);hereditary (6.25%). In 6.25% of cases, PDD were assumed to be of unknown or iatrogenic origin attributable to vaccination (1.56%). 75.51% of parents said that in addition to conventional medical therapies, they also used traditional therapies. The use of this therapeutic alternative would be linked to the perceptions and beliefs that feed the socio-cultural representations of our respondents.
文摘The aspect discussed in the present paper should ont be identified strictly with the natu-ral and geogrophical arid areas in the whole China, but only referred to the seven provincesas Shaanxi, Gansu, Qinhai, Xinjiang and Inner Mongolia. According to the real conditions of the development of tourism which was formedobjectively in the arid areas, it is necessary to consider comprehensively the influence by
文摘<strong>Introduction:</strong> In black Africa, connectivites have been for a long time a source of diagnostic erraticity because of their clinical polymorphism. This study aims to determine the therapeutic itinerary of patients followed for connectivitis in the Internal Medicine Department of the CNHU HKM of Cotonou. <strong>Methodology:</strong> This is a cross-sectional study that included patients followed for connectivitis in the HKM-Cotonou Internal Medicine Department from January 2010 to October 2018. <strong>Results:</strong> Out of 3600 patients hospitalized in the study period, 21 had connectivitis, <i>i.e.</i> a hospital frequency of 0.58%. Of the 21 patients collected, 18 met the inclusion criteria. The mean age was 40 (±11) years old and the youngest was of 21 and the oldest 58. The sex ratio was 17.9. The “Fon” ethnic group was the most represented (33.3%) and 15 (83.3%) subjects were Christians. Systemic lupus erythematosus was the most frequent connectivitis (55.6%). The average time of consultation was 38 months. Witchcraft was the most incriminating cause (78%). Ten (55.5%) patients had resorted to self-medication as their first choice of treatment, 5 (27.8%) to traditional medicine treatment and 3 (16.7%) to prayer for healing. The reasons for the first choice of treatment were satisfaction (44.4%), financial problems (27.8%), trivialization of the disease (16.7%), and advice from family and friends (11.1%). The consultation at the CNHU followed a referral from a first contact health structure (61%) or an initiative of the patient (27.8%). <strong>Conclusion:</strong> Connectivitis is a source of diagnostic error in our context. Awareness must be raised among patients for an early consultation at the first symptoms.
文摘Introduction: The therapeutic pathway affects the patient who changes care facilities. This change is linked to factors such as financial means, geographical accessibility of care facilities, quality of care and the socio-cultural perception of the patient. In countries with limited resources such as Guinea, the therapeutic itinerary remains multiple and hampered by obstacles. The objective of this study was to describe the therapeutic itinerary of patients living with hepatitis B and C at the Donka National Hospital. Material and methods: This was a retrospective, descriptive study lasting 43 months (24 January 2017 - 27 August 2020);it focused on patients living with hepatitis B or C or viral cirrhosis. We collected sociodemographic, clinical and treatment history variables. The data were analysed with SPSS software version 21.0. Results: Out of 5400 patients, the proportion of viral hepatitis B or C represented 393 patients (7.3%). The mean age of our patients was 35 ± 10 years, with extremes of 16 - 77 years. The sex ratio was 2.5. Three hundred and forty-two patients (87%) had recourse to modern medicine, mostly in private facilities (50.6%). One hundred and twenty-five patients (31.8%) had received previous treatment, half of whom (57.6%) had received inappropriate treatment. The delay in treatment was long in 45% of cases. The main reasons for delaying treatment were feeling unwell in 33.3%;not knowing to consult a specialist in 29.9% and feeling that they were being treated with useful drugs in 24.3%. Conclusion: The lack of training of general practitioners on the management of viral hepatitis and the scarcity of awareness campaigns on viral hepatitis contributed to the inadequacy of the management.
文摘晚清来华耶稣会士的论著是研究晚清社会宗教的重要文献资料。英国传教士约翰·亨利·格雷Walks in the City of Canton:with an Itinerary一书以观赏者的视角描述了晚清广州城的历史面貌,尤其是对广州城的佛寺有浓墨重彩的描述。不仅如实记录了佛教道场的历史传承,且重点探析了变动社会中佛门的真实转向。从中可以窥探社会经济背景与宗教文化之间的动态互动关系,进而藉此加深对晚清社会的理解。