To explore the feasibility and superiority of iodine delivery rate(IDR)and tube voltage determined by patients'body mass index(BMI)in coronary CT angiography(CCTA),a total of 1567 patients undertaking CCTA during ...To explore the feasibility and superiority of iodine delivery rate(IDR)and tube voltage determined by patients'body mass index(BMI)in coronary CT angiography(CCTA),a total of 1567 patients undertaking CCTA during Feb.and Dec.2016 were enrolled and divided into two groups.In the control group,the IDR and tube voltage were fixed,while in the experimental group,the IDR and tube voltage were determined by patients,BMI.The volume of iodinated contrast media(ICM),extravasation rate,extravasation volume,extravasation recovery interval,incidence rate of adverse reactions,effective dose(ED)and image quality of the two groups were compared.The experiments demonstrated that the ICM volume,extravasation rate,extravasation volume,extravasation recovery interval,incidence of adverse reactions and ED were lower or shorter in the experimental group than in the control group,and the differences were statistically significant(all P<0.05).However,there were no significant differences in the mean CT value,image noise,signal to noise ratio and contrast to noise ratio between the two groups(all P<0.05),which were consistent with the diagnosticians*subjective evaluation outcomes.Our findings suggested that in CCTA,it is feasible to determine the IDR and tube voltage based on patients'BMI;low tube voltage and IDR are superior to the fixed tube voltage and IDR and are worthy of clinical promotion.展开更多
Available online Iodinated X-ray contrast media (ICMs) are clinical drugs used to enhance the imaging effect.Triiodobenzene ring structures of ICMs lead to its extremely high chemical stability,biological inertness,wh...Available online Iodinated X-ray contrast media (ICMs) are clinical drugs used to enhance the imaging effect.Triiodobenzene ring structures of ICMs lead to its extremely high chemical stability,biological inertness,which makes it difficult to be completely removed by traditional water treatment processes.Hence,considerable concentration of ICMs can be frequently detected in aquatic environment.Relying on the strong oxidation capacity of HO·or SO_(4)^(·-),various advanced oxidation processes (AOPs) have demonstrated substantial removal efficiency for ICMs.It is evident that ICMs can be decomposed mainly through(1) deiodination,(2) dehydration,(3) decarboxylation,(4) H-abstraction,(5) hydroxyl addition,(6) hydroxyl substitution,(7) oxidation of alcohol groups,(8) cleavage of amide bond,and (9) amino oxidation.However,during the ICMs removal process,the C-I bonds of ICMs molecules are broken,giving rise to the formation of cytotoxic iodination disinfection by-products (I-DBPs) that are potentially more harmful to the ecosystem and human health than their parent compounds.To better understand the technology gaps,this review elaborates the major AOPs which are effective for ICMs removal and emphasizes on the main degradation routes of ICMs in different oxidation system.Some prevailing concerns and challenges are discussed for optimizing the ICMs treatment process.展开更多
文摘To explore the feasibility and superiority of iodine delivery rate(IDR)and tube voltage determined by patients'body mass index(BMI)in coronary CT angiography(CCTA),a total of 1567 patients undertaking CCTA during Feb.and Dec.2016 were enrolled and divided into two groups.In the control group,the IDR and tube voltage were fixed,while in the experimental group,the IDR and tube voltage were determined by patients,BMI.The volume of iodinated contrast media(ICM),extravasation rate,extravasation volume,extravasation recovery interval,incidence rate of adverse reactions,effective dose(ED)and image quality of the two groups were compared.The experiments demonstrated that the ICM volume,extravasation rate,extravasation volume,extravasation recovery interval,incidence of adverse reactions and ED were lower or shorter in the experimental group than in the control group,and the differences were statistically significant(all P<0.05).However,there were no significant differences in the mean CT value,image noise,signal to noise ratio and contrast to noise ratio between the two groups(all P<0.05),which were consistent with the diagnosticians*subjective evaluation outcomes.Our findings suggested that in CCTA,it is feasible to determine the IDR and tube voltage based on patients'BMI;low tube voltage and IDR are superior to the fixed tube voltage and IDR and are worthy of clinical promotion.
基金supported by the Science&Technology Innovation Action Plan of Shanghai under the Belt and Road Initiative (No.19230742800)。
文摘Available online Iodinated X-ray contrast media (ICMs) are clinical drugs used to enhance the imaging effect.Triiodobenzene ring structures of ICMs lead to its extremely high chemical stability,biological inertness,which makes it difficult to be completely removed by traditional water treatment processes.Hence,considerable concentration of ICMs can be frequently detected in aquatic environment.Relying on the strong oxidation capacity of HO·or SO_(4)^(·-),various advanced oxidation processes (AOPs) have demonstrated substantial removal efficiency for ICMs.It is evident that ICMs can be decomposed mainly through(1) deiodination,(2) dehydration,(3) decarboxylation,(4) H-abstraction,(5) hydroxyl addition,(6) hydroxyl substitution,(7) oxidation of alcohol groups,(8) cleavage of amide bond,and (9) amino oxidation.However,during the ICMs removal process,the C-I bonds of ICMs molecules are broken,giving rise to the formation of cytotoxic iodination disinfection by-products (I-DBPs) that are potentially more harmful to the ecosystem and human health than their parent compounds.To better understand the technology gaps,this review elaborates the major AOPs which are effective for ICMs removal and emphasizes on the main degradation routes of ICMs in different oxidation system.Some prevailing concerns and challenges are discussed for optimizing the ICMs treatment process.
