Differential susceptibility SIR epidemic models with time delay and pulse vaccination is studied in this paper. We show that there exists an infection-free periodic solution by using the comparison method, which is gl...Differential susceptibility SIR epidemic models with time delay and pulse vaccination is studied in this paper. We show that there exists an infection-free periodic solution by using the comparison method, which is globally attractive provided that R1 〈 1, and that R2 〉 1 implies the disease is permanent, which means that after some period of time the disease will become endemic.展开更多
We study the application of a pulse vaccination strategy to eradicate the slowly progressing diseases that have infectiousness in latent period. We derive the condition in which eradication solution is a global attrac...We study the application of a pulse vaccination strategy to eradicate the slowly progressing diseases that have infectiousness in latent period. We derive the condition in which eradication solution is a global attractor, this condition depends on pulse vaccination proportion p. We also obtain the condition of the global asymptotic stability of the solution. The condition shows that large enough pulse vaccination proportion and relatively small interpulse time lead to the eradication of the diseases. Moreover the results of the theoretical study might be instructive to the epidemiology of HIV.展开更多
In this paper, an SEIRS epidemic model with pulse vaccination and two time delays is proposed. By using stroboscopic map and comparison principle, the disease-free periodic solution(DFPS for short) is obtained and the...In this paper, an SEIRS epidemic model with pulse vaccination and two time delays is proposed. By using stroboscopic map and comparison principle, the disease-free periodic solution(DFPS for short) is obtained and the global asymptotic stability of the DFPS is proved. The sufficient conditions for the permanence of the model are obtained. In addition, numerical simulations are done to confirm our theoretical results.展开更多
This paper discusses the application of a pulse vaccination strategy to prevent and control some infectious diseases, which is described by age-structured SIR model in which susceptible and recovered individuals are s...This paper discusses the application of a pulse vaccination strategy to prevent and control some infectious diseases, which is described by age-structured SIR model in which susceptible and recovered individuals are structured by chronological age, while infected individuals are structured by infection age （duration since infection）. The time dependent disease-free equilibrium is determined, for which an explicit expression exists. The analytical results show that there exists a globally stable infectiomfree situation if the impulsive period T and proportion p satisfy Ro（p,T） 〈 1. Optimal problem is discussed： Pulse vaccination strategy with minimal costs at given R0（p, T） 〈 1.展开更多
Considering the fact that the production and provision of some vaccines are ordered and governed by the government according to the history data of disease, a kind of SIR model with constant vaccination rate and impul...Considering the fact that the production and provision of some vaccines are ordered and governed by the government according to the history data of disease, a kind of SIR model with constant vaccination rate and impulsive state feedback control is presented. The dynamical properties of semi-continuous three-dimensional SIR system can be obtained by discussing the properties of the corresponding two-dimensional system in the limit set. The existence and uniqueness of order-1 periodic solution are discussed by using the successive function and the compression mapping theorem. A new theorem for the orbital stability of order-1 periodic solution is proved by geometric method. Finally, numerical simulations are given to verify the mathematical results and some conclusions are given. The results show that the disease can be controlled to a lower level by means of impulsive state feedback control strategy, but cannot be eradicated.展开更多
基金Supported by the National Natural Science Foundation of China（10971001） Supported by Henan Science and Technology Department（082102140025, 092300410228）
文摘Differential susceptibility SIR epidemic models with time delay and pulse vaccination is studied in this paper. We show that there exists an infection-free periodic solution by using the comparison method, which is globally attractive provided that R1 〈 1, and that R2 〉 1 implies the disease is permanent, which means that after some period of time the disease will become endemic.
基金The research is supported by the National Science Foundation of Henan Province(No. 0611051800).
文摘We study the application of a pulse vaccination strategy to eradicate the slowly progressing diseases that have infectiousness in latent period. We derive the condition in which eradication solution is a global attractor, this condition depends on pulse vaccination proportion p. We also obtain the condition of the global asymptotic stability of the solution. The condition shows that large enough pulse vaccination proportion and relatively small interpulse time lead to the eradication of the diseases. Moreover the results of the theoretical study might be instructive to the epidemiology of HIV.
基金The Natural Science Basic Research Plan in Shaanxi Province of China(2018JM1011)Natural Science Basic Research Plan in Shaanxi Province of China(2017JQ1014)NSF of China(11701041)
文摘In this paper, an SEIRS epidemic model with pulse vaccination and two time delays is proposed. By using stroboscopic map and comparison principle, the disease-free periodic solution(DFPS for short) is obtained and the global asymptotic stability of the DFPS is proved. The sufficient conditions for the permanence of the model are obtained. In addition, numerical simulations are done to confirm our theoretical results.
基金supported by Natural Science Foundation of Henan Province under Grant No.092300410206Science and Technology Program of Educational Department of Henan Province under Grant No. 2009A110015
文摘This paper discusses the application of a pulse vaccination strategy to prevent and control some infectious diseases, which is described by age-structured SIR model in which susceptible and recovered individuals are structured by chronological age, while infected individuals are structured by infection age （duration since infection）. The time dependent disease-free equilibrium is determined, for which an explicit expression exists. The analytical results show that there exists a globally stable infectiomfree situation if the impulsive period T and proportion p satisfy Ro（p,T） 〈 1. Optimal problem is discussed： Pulse vaccination strategy with minimal costs at given R0（p, T） 〈 1.
文摘Considering the fact that the production and provision of some vaccines are ordered and governed by the government according to the history data of disease, a kind of SIR model with constant vaccination rate and impulsive state feedback control is presented. The dynamical properties of semi-continuous three-dimensional SIR system can be obtained by discussing the properties of the corresponding two-dimensional system in the limit set. The existence and uniqueness of order-1 periodic solution are discussed by using the successive function and the compression mapping theorem. A new theorem for the orbital stability of order-1 periodic solution is proved by geometric method. Finally, numerical simulations are given to verify the mathematical results and some conclusions are given. The results show that the disease can be controlled to a lower level by means of impulsive state feedback control strategy, but cannot be eradicated.
