Wilson’s disease is an autosomal-recessive disorder with an ATP7B mutation that causes a functional failure of the copper-transporting protein ATP7B(1,2).As a result,unbound copper in the blood increases,and due to c...Wilson’s disease is an autosomal-recessive disorder with an ATP7B mutation that causes a functional failure of the copper-transporting protein ATP7B(1,2).As a result,unbound copper in the blood increases,and due to copper accumulation,multiple organs show various symptoms,e.g.,Kayser-Fleischer rings,acute liver failure,liver cirrhosis,liver cancer,dysarthria,tremors,character changes,renal disorders,rheumatological symptoms,endocrinopathy,heart failure,and arrhythmias(3,4).This disease afflicts approximately 1 in 40,000 people,with approximately 1 carrier for every 100 people,and early diagnosis is difficult.展开更多
Celestial mechanics has been a classical field of astronomy. Only a few astronomers were in this field and not so many papers on this subject had been published during the first half of the 20th century. However, as t...Celestial mechanics has been a classical field of astronomy. Only a few astronomers were in this field and not so many papers on this subject had been published during the first half of the 20th century. However, as the beauty of classical dynamics and celestial mechanics attracted me very much, I decided to take celestial mechanics as my research subject and entered university, where a very famous professor of celestial mechanics was a member of the faculty. Then as artificial satellites were launched starting from October 1958, new topics were investigated in the field of celestial mechanics. Moreover, planetary rings, asteroids with moderate values of eccentricity, inclination and so on have become new fields of celestial mechanics. In fact I have tried to solve such problems in an analytical way. Finally, to understand what gravitation is I joined the TAMA300 gravitational wave detector group.展开更多
文摘Wilson’s disease is an autosomal-recessive disorder with an ATP7B mutation that causes a functional failure of the copper-transporting protein ATP7B(1,2).As a result,unbound copper in the blood increases,and due to copper accumulation,multiple organs show various symptoms,e.g.,Kayser-Fleischer rings,acute liver failure,liver cirrhosis,liver cancer,dysarthria,tremors,character changes,renal disorders,rheumatological symptoms,endocrinopathy,heart failure,and arrhythmias(3,4).This disease afflicts approximately 1 in 40,000 people,with approximately 1 carrier for every 100 people,and early diagnosis is difficult.
文摘Celestial mechanics has been a classical field of astronomy. Only a few astronomers were in this field and not so many papers on this subject had been published during the first half of the 20th century. However, as the beauty of classical dynamics and celestial mechanics attracted me very much, I decided to take celestial mechanics as my research subject and entered university, where a very famous professor of celestial mechanics was a member of the faculty. Then as artificial satellites were launched starting from October 1958, new topics were investigated in the field of celestial mechanics. Moreover, planetary rings, asteroids with moderate values of eccentricity, inclination and so on have become new fields of celestial mechanics. In fact I have tried to solve such problems in an analytical way. Finally, to understand what gravitation is I joined the TAMA300 gravitational wave detector group.