The morphology characteristics of cell apoptosis of the malignant tumour cells in magnetic field-treated mouse was observed for the first time. The apoptotic cancer cell contracted, became rounder and divorced from ad...The morphology characteristics of cell apoptosis of the malignant tumour cells in magnetic field-treated mouse was observed for the first time. The apoptotic cancer cell contracted, became rounder and divorced from adjacent cells; the heterochromatin condensed and coagulated together along the inner side of the nuclear membrane; the endoplasmic reticulums(ER) expanded and fused with the cellular membrane; many apoptotic bodies which were packed by the cellular membrane appeared and were devoured by some lymphocytes and plasma. Apoptosis of cancer cells was detected by terminal deoxynucleotidyl transferase mediated in situ nick end labeling(TUNEL). It was found that the number of apoptosis cancer cells of the sample treated by the magnetic field is more than that of the control sample. The growth of malignant tumour in mice was inhibited and the ability of immune cell to dissolve cancer cells was improved by ultralow frequency(ULF) pulsed gradient magnetic field; the nuclei DNA contents decreased, indicating that magnetic field can block DNA replication and inhibit mitosis of cancer cells. It was suggested that magnetic field could inhibit the metabolism of cancer cell, lower its malignancy, and restrain its rapid and heteromorphic growth. Since ULF pulsed gradient magnetic field can induce apoptosis of cancer cells and inhibit the growth of malignant tumour, it could be used as a new method to treat cancer.展开更多
Among electromagnetic methods of short-term earthquake prediction,an approach is being actively developed based on the phenomenon of magnetic ultra-low-frequency(ULF)power depression occurring a few days before an ear...Among electromagnetic methods of short-term earthquake prediction,an approach is being actively developed based on the phenomenon of magnetic ultra-low-frequency(ULF)power depression occurring a few days before an earthquake.In particular,a nighttime geomagnetic power depression in the band 0.03-0.05 Hz was observed approximately 5 days before the catastrophic Tohoku 2011 earthquake.To verify the reliability of this method,we performed an extended analysis using data from magnetometer arrays JMA,MAGDAS,PWING,and INTERMAGNET.The selected stations included sites close to the epicenter(<300 km)and remote points(~10000 km).The band-integrated spectral power of nighttime magnetic noise decreased significantly from March 6-9,several days before the earthquake.However,such variations occur simultaneously not only at nearby stations but also at distant stations.During this event,the ULF power depression was caused by low global geomagnetic activity,as evidenced by the planetary index SME.Thus,the depression of geomagnetic ULF noise cannot be considered a reliable short-term precursor.展开更多
This study reports the rare ultralow-frequency(ULF) wave activity associated with the solar wind dynamic pressure enhancement that was successively observed by the GOES-17(Geostationary Operational Environmental Satel...This study reports the rare ultralow-frequency(ULF) wave activity associated with the solar wind dynamic pressure enhancement that was successively observed by the GOES-17(Geostationary Operational Environmental Satellite) in the magnetosphere, the CSES(China Seismo-Electromagnetic Satellite) in the ionosphere, and the THEMIS ground-based observatories(GBO) GAKO and EAGL in the Earth's polar region during the main phase of an intense storm on 4 November 2021. Along with the enhanced-pressure solar wind moving tailward, the geomagnetic field structure experienced a large-scale change. From dawn/dusk sides to midnight, the GAKO, EAGL, and GOES-17 sequentially observed the ULF waves in a frequency range of0.04–0.36 Hz at L shells of ~5.07, 6.29, and 5.67, respectively. CSES also observed the ULF wave event with the same frequency ranges at wide L-shells of 2.52–6.22 in the nightside ionosphere. The analysis results show that the ULF waves at ionospheric altitude were mixed toroidal-poloidal mode waves. Comparing the ULF waves observed in different regions, we infer that the nightside ULF waves were directly or indirectly excited by the solar wind dynamic pressure increase: in the area of L-shells~2.52–6.29, the magnetic field line resonances(FLRs) driven by the solar wind dynamic pressure increase is an essential excitation source;on the other hand, around L~3.29, the ULF waves can also be excited by the outward expansion of the plasmapause owing to the decrease of the magnetospheric convection, and in the region of L-shells ~5.19–6.29, the ULF waves are also likely excited by the ion cyclotron instabilities driven by the solar wind dynamic pressure increase.展开更多
The ultra low frequency (ULF) wave in magnetosphere can act as an important means for solar wind energy inward transmission.This paper quantitatively analyzes the propagation process of the ULF wave triggered by the i...The ultra low frequency (ULF) wave in magnetosphere can act as an important means for solar wind energy inward transmission.This paper quantitatively analyzes the propagation process of the ULF wave triggered by the interplanetary shock propagating from inner magnetosphere equatorial plane along magnetic field lines to the top of the ionosphere and below ionosphere propagating process and establishes a relatively complete magnetosphere-ionosphere-atmosphere propagation model which can be used to study the relationship between the amplitude of the ULF waves triggered by the interplanetary shock wave in magnetospheric space and the magnetic effect caused by the ULF waves.After a comparison with recent observations,we found that: in the event during November 7,2004 that an interplanetary shock wave interacted with the magnetosphere,Cluster satellites observed that electric field fluctuations and the band-pass filtered result of ground stations meridional component had similar characteristics.Comparing with the geomagnetic measurement near the footprints,we found that the electric field disturbance in the magnetosphere spread along the ground magnetic field lines in the form of the ULF waves and changed into geomagnetic disturbance.The result reveals that the ULF wave is in contact with the ground geomagnetic observation.The ULF waves couple with ionized components in ionosphere and spread to the ground in the form of electromagnetic waves.In this research,we believe that the magnetosphere,ionosphere and ground magnetic effects caused by interplanetary shock wave are the same physical phenomena responding in different locations.Based on the overall consideration of entire electromagnetic response to the interplanetary shock wave,we found that the correlation between CLUSTER multi-satellite observation and geomagnetic station observation is due to the ULF wave propagated in magnetosphere-ionosphere-atmosphere system,and we quantitatively interpreted this response process.展开更多
The anomalies of electric-magnetic field and self-potential before earthquakes are important precursory phenom-ena. A simulating experiment study on the variations in ultra-low frequency (ULF) magnetic field and self-...The anomalies of electric-magnetic field and self-potential before earthquakes are important precursory phenom-ena. A simulating experiment study on the variations in ultra-low frequency (ULF) magnetic field and self-poten-tial during rock cracking was carried out in a magnetic field-free space. The results revealing in detail the whole process of the occurrences of electric and magnetic anomalies are significant for understanding the microscopic mechanism of ULF electric and magnetic signals. The experiment indicated that at the initial stage the slow changes in strain, self-potential and magnetic field with small amounts appeared firstly near the source of initial cracking, and then extended as the crack developed on. In the time domain, the self-potential anomaly emerged first and ULF magnetic field changes arose then. The shape of the ULF electric and magnetic anomaly varied ob-viously in early-, mid- and late-term of the test. The authors attributed the pulse-like changes of self-potential to the generation and movement of the accumulated electric charges during the cracking caused by charge separation on the crack tips within the sample. While the magnetic pulses of shorter-period at the last stage of the test, may be induced by instantaneous electric current of the accumulated charge during the cracking acceleration. The technical method and the observational results of this experiment are given in detail and the microscopic mechanism of elec-tric and magnetic precursors before earthquake are discussed in the present paper as well.展开更多
基金The authors thank Prof. Li Tongping of the Pathological Unit of Fundamental Medical School,Tongji Medical University for his kind instruction and help. This work was supported by the National Natural Science Foundation of China(Grant No. 39870823) and
文摘The morphology characteristics of cell apoptosis of the malignant tumour cells in magnetic field-treated mouse was observed for the first time. The apoptotic cancer cell contracted, became rounder and divorced from adjacent cells; the heterochromatin condensed and coagulated together along the inner side of the nuclear membrane; the endoplasmic reticulums(ER) expanded and fused with the cellular membrane; many apoptotic bodies which were packed by the cellular membrane appeared and were devoured by some lymphocytes and plasma. Apoptosis of cancer cells was detected by terminal deoxynucleotidyl transferase mediated in situ nick end labeling(TUNEL). It was found that the number of apoptosis cancer cells of the sample treated by the magnetic field is more than that of the control sample. The growth of malignant tumour in mice was inhibited and the ability of immune cell to dissolve cancer cells was improved by ultralow frequency(ULF) pulsed gradient magnetic field; the nuclei DNA contents decreased, indicating that magnetic field can block DNA replication and inhibit mitosis of cancer cells. It was suggested that magnetic field could inhibit the metabolism of cancer cell, lower its malignancy, and restrain its rapid and heteromorphic growth. Since ULF pulsed gradient magnetic field can induce apoptosis of cancer cells and inhibit the growth of malignant tumour, it could be used as a new method to treat cancer.
基金supported by Grant 22-17-00125 from the Russian Science Foundation.
文摘Among electromagnetic methods of short-term earthquake prediction,an approach is being actively developed based on the phenomenon of magnetic ultra-low-frequency(ULF)power depression occurring a few days before an earthquake.In particular,a nighttime geomagnetic power depression in the band 0.03-0.05 Hz was observed approximately 5 days before the catastrophic Tohoku 2011 earthquake.To verify the reliability of this method,we performed an extended analysis using data from magnetometer arrays JMA,MAGDAS,PWING,and INTERMAGNET.The selected stations included sites close to the epicenter(<300 km)and remote points(~10000 km).The band-integrated spectral power of nighttime magnetic noise decreased significantly from March 6-9,several days before the earthquake.However,such variations occur simultaneously not only at nearby stations but also at distant stations.During this event,the ULF power depression was caused by low global geomagnetic activity,as evidenced by the planetary index SME.Thus,the depression of geomagnetic ULF noise cannot be considered a reliable short-term precursor.
基金supported by the National Key Research and Development Program of China (Grant No. 2023YFE0117300)the National Natural Science Foundation of China (Grant No. 4187417)the APSCO Earthquake Research Project Phase Ⅱ, and the Dragon 5 Cooperation 2020-2024 (Grant No. 59236)。
文摘This study reports the rare ultralow-frequency(ULF) wave activity associated with the solar wind dynamic pressure enhancement that was successively observed by the GOES-17(Geostationary Operational Environmental Satellite) in the magnetosphere, the CSES(China Seismo-Electromagnetic Satellite) in the ionosphere, and the THEMIS ground-based observatories(GBO) GAKO and EAGL in the Earth's polar region during the main phase of an intense storm on 4 November 2021. Along with the enhanced-pressure solar wind moving tailward, the geomagnetic field structure experienced a large-scale change. From dawn/dusk sides to midnight, the GAKO, EAGL, and GOES-17 sequentially observed the ULF waves in a frequency range of0.04–0.36 Hz at L shells of ~5.07, 6.29, and 5.67, respectively. CSES also observed the ULF wave event with the same frequency ranges at wide L-shells of 2.52–6.22 in the nightside ionosphere. The analysis results show that the ULF waves at ionospheric altitude were mixed toroidal-poloidal mode waves. Comparing the ULF waves observed in different regions, we infer that the nightside ULF waves were directly or indirectly excited by the solar wind dynamic pressure increase: in the area of L-shells~2.52–6.29, the magnetic field line resonances(FLRs) driven by the solar wind dynamic pressure increase is an essential excitation source;on the other hand, around L~3.29, the ULF waves can also be excited by the outward expansion of the plasmapause owing to the decrease of the magnetospheric convection, and in the region of L-shells ~5.19–6.29, the ULF waves are also likely excited by the ion cyclotron instabilities driven by the solar wind dynamic pressure increase.
基金supported by the key project of National Natural Science Foundation of China (Grant No. 40831061)the Specialized Research Fund for State Key Laboratories of China
文摘The ultra low frequency (ULF) wave in magnetosphere can act as an important means for solar wind energy inward transmission.This paper quantitatively analyzes the propagation process of the ULF wave triggered by the interplanetary shock propagating from inner magnetosphere equatorial plane along magnetic field lines to the top of the ionosphere and below ionosphere propagating process and establishes a relatively complete magnetosphere-ionosphere-atmosphere propagation model which can be used to study the relationship between the amplitude of the ULF waves triggered by the interplanetary shock wave in magnetospheric space and the magnetic effect caused by the ULF waves.After a comparison with recent observations,we found that: in the event during November 7,2004 that an interplanetary shock wave interacted with the magnetosphere,Cluster satellites observed that electric field fluctuations and the band-pass filtered result of ground stations meridional component had similar characteristics.Comparing with the geomagnetic measurement near the footprints,we found that the electric field disturbance in the magnetosphere spread along the ground magnetic field lines in the form of the ULF waves and changed into geomagnetic disturbance.The result reveals that the ULF wave is in contact with the ground geomagnetic observation.The ULF waves couple with ionized components in ionosphere and spread to the ground in the form of electromagnetic waves.In this research,we believe that the magnetosphere,ionosphere and ground magnetic effects caused by interplanetary shock wave are the same physical phenomena responding in different locations.Based on the overall consideration of entire electromagnetic response to the interplanetary shock wave,we found that the correlation between CLUSTER multi-satellite observation and geomagnetic station observation is due to the ULF wave propagated in magnetosphere-ionosphere-atmosphere system,and we quantitatively interpreted this response process.
基金Joint Seismological Science Foundation of China (95-07-434) and the MOST under contract 2001BA601B02.
文摘The anomalies of electric-magnetic field and self-potential before earthquakes are important precursory phenom-ena. A simulating experiment study on the variations in ultra-low frequency (ULF) magnetic field and self-poten-tial during rock cracking was carried out in a magnetic field-free space. The results revealing in detail the whole process of the occurrences of electric and magnetic anomalies are significant for understanding the microscopic mechanism of ULF electric and magnetic signals. The experiment indicated that at the initial stage the slow changes in strain, self-potential and magnetic field with small amounts appeared firstly near the source of initial cracking, and then extended as the crack developed on. In the time domain, the self-potential anomaly emerged first and ULF magnetic field changes arose then. The shape of the ULF electric and magnetic anomaly varied ob-viously in early-, mid- and late-term of the test. The authors attributed the pulse-like changes of self-potential to the generation and movement of the accumulated electric charges during the cracking caused by charge separation on the crack tips within the sample. While the magnetic pulses of shorter-period at the last stage of the test, may be induced by instantaneous electric current of the accumulated charge during the cracking acceleration. The technical method and the observational results of this experiment are given in detail and the microscopic mechanism of elec-tric and magnetic precursors before earthquake are discussed in the present paper as well.
