AIM: To compare the short-term visual outcomes, residual refractive cylinder, and rotation stability after Tecnis toric intraocular lens(IOL) implantation during femtosecond laserassisted cataract surgery(Femto phaco)...AIM: To compare the short-term visual outcomes, residual refractive cylinder, and rotation stability after Tecnis toric intraocular lens(IOL) implantation during femtosecond laserassisted cataract surgery(Femto phaco) and conventional phacoemulsification surgery(Conventional phaco).METHODS: In a prospective cohort study, Conventional phaco and Femto phaco(anterior capsulotomy and lens fragmentation by a femtosecond laser) with Tecnis toric IOL implantation were performed in 40 eyes from 36 patients and 37 eyes from 33 patients, respectively. The uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA), and manifest refraction were assessed during 1 d, 1 wk, and 1 mo follow-ups. The orientation of the Tecnis Toric IOL was evaluated during 1 wk and 1 mo follow-ups.RESULTS: There were no significant differences in UDCA or CDVA between two groups at 1 mo postoperatively, though relatively more subjects had UDVA values of 20/25 or better in Femto phaco group than in the Conventional group(P>0.05). A lower but not significantly lower rate of having more than 5° of IOL rotation was observed in Femto phaco group at the 1-month follow-up, while a significant lower rate of residual astigmatism of ≤1 D was observed in Femto phaco group.CONCLUSION: The Femto phaco group has significantly more subjects with the residual astigmatism of ≤1 D, but there are no significant differences in rotation stability and visual outcomes as compared with the Conventional phaco group after the application of the Tecnis toric IOL in this cohort.展开更多
目的比较飞秒激光辅助白内障超声乳化手术与传统超声乳化手术后自然状态下高阶像差、调制传递函数值(modulation transfer function,MTF)的变化,为白内障患者术前手术方式方案选择以及提高白内障患者术后视觉质量提供指导。方法对2016年...目的比较飞秒激光辅助白内障超声乳化手术与传统超声乳化手术后自然状态下高阶像差、调制传递函数值(modulation transfer function,MTF)的变化,为白内障患者术前手术方式方案选择以及提高白内障患者术后视觉质量提供指导。方法对2016年7月至2017年7月在山东潍坊眼科医院就诊行白内障超声乳化吸除联合人工晶状体(IOL)植入术,随机选取且随访资料完整白内障患者82例100眼,按手术方式分组:实验组为飞秒激光辅助白内障超声乳化手术组45例52眼,对照组为传统超声乳化手术组37例48眼。术后1天、1周、1月分别测量2组患者的最佳矫正视力(BCVA),使用iTrace视功能分析仪测量两组术眼自然状态下取瞳孔直径为3mm的高阶像差(总眼高阶像差、球差、彗差、三叶草像差)及总高阶像差下的MTF。数据采用单因素方差分析。结果 2组的BCVA在术后1天、1周有差异,有统计学意义,术后1月的BCVA无明显差异,不具统计学意义;术后1天、1周、1月实验组术眼自然状态下取得瞳孔直径为3mm全眼的总高阶像差、慧差、球差、三叶草像差优于对照组,具有统计学意义,高阶像差下MTF优于对照组,具有统计学意义;术后1天、1周、1月实验组术眼全眼总高阶像差均值低于对照组,两组都随时间变化呈递减趋势,且两者均值随时间变化逐渐接近。术后1天、1周、1月实验组术眼总高阶像差下的MTF均值高于对照组,两组都随时间变化呈递增趋势,且两者均值随时间变化逐渐接近。结论飞秒激光辅助白内障手术与传统超声乳化白内障手术相比具有更好的视觉质量。飞秒激光辅助白内障手术术后早期能获得更好的视觉质量。展开更多
AIM： To evaluate human lens epithelium cell apoptosis and epithelial to mesenchymal transition （EMT） induced by femtosecond laser in femtosecond laser assisted cataract surgery （FLACS）. METHODS： Sixty cataract ...AIM： To evaluate human lens epithelium cell apoptosis and epithelial to mesenchymal transition （EMT） induced by femtosecond laser in femtosecond laser assisted cataract surgery （FLACS）. METHODS： Sixty cataract patients with N2 to N3 stage according to the LOCS III were enrolled in this study and divided into three groups randomly： FLACSl group （cataract surgery by FLACS with LenSx）, FLACS2 group （cataract surgery by FLACS with LensAR） and manual group （cataract surgery by phacoemulsification）. Patients in two FLACS groups performed anterior capsulotomy by LenSx or LensAR laser system. Patients in the manual group were performed continuous curvilinear capsulorrhexis （CCC） manually. The anterior capsules were fixed right after moved out of eye. Hematoxylin-eosine staining, immunofluorescence staining and real-time PCR were performed in order to observe human lens epithelium cells changes after cataract surgery. RESULTS： The capsule cutting edge was shown irregularity and roughness in two FLACS groups and smooth edge in manual capsulotomy by pathologic staining. Irregularities of the cell configuration with partly swollen and destroyed nuclei were observed in two FLACS groups. Femtosecond laser could induce a significantly higher cell apoptosis in human lens epithelium cell than manually performed CCC （P〈0.05）. Lens epithelium cells apoptosis were correlated with femtosecond laser duration according to Pearson correlation analysis. Decreased N-cadherin expression, alpha-SMA and FSP-1 level in two FLACS groups showed the inhibition of cell EMT. CONCLUSION： Femtosecond laser may affect the apoptosis and EMT of lens epithelium cells which are under the peeled central lens capsule.展开更多
AIM： To evaluate blood pressure（BP） changes during phacoemulsification（PC） and femtosecond laser（FSL）-assisted cataract surgery.METHODS： A retrospective chart review was performed for all patients who received...AIM： To evaluate blood pressure（BP） changes during phacoemulsification（PC） and femtosecond laser（FSL）-assisted cataract surgery.METHODS： A retrospective chart review was performed for all patients who received traditional phacoemulsification surgery（PC group） and FSL-assisted cataract surgery（FS group） from July 2013 to December 2014. Totally 206 eyes from 133 patients receiving the two types of procedures were included.Patient characteristics（age, gender, and hypertension history）, pre- and post-operative BPs were collected.RESULTS： The pro-operative systolic and diastolic BPs（mm Hg） were 124.89 ±20.48 vs 126.98 ±16.85, and71.88 ±9.81 vs 73.56 ±10.03, in PC and FS groups,respectively. While the post-operative systolic and diastolic BPs（mm Hg） were 130.13 ±22.59 vs 134.77 ±17.52, and 73.41 ±11.62 vs 78.89 ±12.2, in PC and FS groups, respectively. Paired-sample t-tests showed obvious systolic and diastolic BP elevations in FS group after surgery（P =0.001 and 0.007） and no reliability in PC group（P =0.094 and 0.359）. A linear regression model revealed systolic and diastolic BP elevations,which were related to longer surgical times for FS group（P =0.008 and 0.021）. Age, gender, and hypertension history were not correlated with blood pressure elevation in either group.CONCLUSION： BP increases but at a limited level after FSL-assisted cataract surgery compared to traditional phacoemulsification展开更多
基金Supported by Zhejiang Province Key Research and Development Program(No.2015C03042)
文摘AIM: To compare the short-term visual outcomes, residual refractive cylinder, and rotation stability after Tecnis toric intraocular lens(IOL) implantation during femtosecond laserassisted cataract surgery(Femto phaco) and conventional phacoemulsification surgery(Conventional phaco).METHODS: In a prospective cohort study, Conventional phaco and Femto phaco(anterior capsulotomy and lens fragmentation by a femtosecond laser) with Tecnis toric IOL implantation were performed in 40 eyes from 36 patients and 37 eyes from 33 patients, respectively. The uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA), and manifest refraction were assessed during 1 d, 1 wk, and 1 mo follow-ups. The orientation of the Tecnis Toric IOL was evaluated during 1 wk and 1 mo follow-ups.RESULTS: There were no significant differences in UDCA or CDVA between two groups at 1 mo postoperatively, though relatively more subjects had UDVA values of 20/25 or better in Femto phaco group than in the Conventional group(P>0.05). A lower but not significantly lower rate of having more than 5° of IOL rotation was observed in Femto phaco group at the 1-month follow-up, while a significant lower rate of residual astigmatism of ≤1 D was observed in Femto phaco group.CONCLUSION: The Femto phaco group has significantly more subjects with the residual astigmatism of ≤1 D, but there are no significant differences in rotation stability and visual outcomes as compared with the Conventional phaco group after the application of the Tecnis toric IOL in this cohort.
文摘目的比较飞秒激光辅助白内障超声乳化手术与传统超声乳化手术后自然状态下高阶像差、调制传递函数值(modulation transfer function,MTF)的变化,为白内障患者术前手术方式方案选择以及提高白内障患者术后视觉质量提供指导。方法对2016年7月至2017年7月在山东潍坊眼科医院就诊行白内障超声乳化吸除联合人工晶状体(IOL)植入术,随机选取且随访资料完整白内障患者82例100眼,按手术方式分组:实验组为飞秒激光辅助白内障超声乳化手术组45例52眼,对照组为传统超声乳化手术组37例48眼。术后1天、1周、1月分别测量2组患者的最佳矫正视力(BCVA),使用iTrace视功能分析仪测量两组术眼自然状态下取瞳孔直径为3mm的高阶像差(总眼高阶像差、球差、彗差、三叶草像差)及总高阶像差下的MTF。数据采用单因素方差分析。结果 2组的BCVA在术后1天、1周有差异,有统计学意义,术后1月的BCVA无明显差异,不具统计学意义;术后1天、1周、1月实验组术眼自然状态下取得瞳孔直径为3mm全眼的总高阶像差、慧差、球差、三叶草像差优于对照组,具有统计学意义,高阶像差下MTF优于对照组,具有统计学意义;术后1天、1周、1月实验组术眼全眼总高阶像差均值低于对照组,两组都随时间变化呈递减趋势,且两者均值随时间变化逐渐接近。术后1天、1周、1月实验组术眼总高阶像差下的MTF均值高于对照组,两组都随时间变化呈递增趋势,且两者均值随时间变化逐渐接近。结论飞秒激光辅助白内障手术与传统超声乳化白内障手术相比具有更好的视觉质量。飞秒激光辅助白内障手术术后早期能获得更好的视觉质量。
文摘目的通过观察行飞秒激光辅助白内障手术联合Restor+2.5 D和Restor+3.0 D多焦点人工晶状体(MIOL)双眼植入术后3个月患者的双眼全程视力、对比敏感度、视觉干扰现象及主观满意度等指标,综合评价其术后视觉质量及老视矫正的效果。方法连续选择自2015年3月至2017年3月就诊于重庆爱尔麦格眼科医院的双眼白内障合并老视患者105例(210只眼),采用信封法随机分为观察组和对照组,观察组行飞秒激光辅助白内障超声乳化吸出联合双眼先后植入Restor+2.5 D和Restor+3.0 D MIOL,对照组行飞秒激光辅助白内障超声乳化吸出联合双眼植入Restor+3.0 D MIOL。术后早期观察患者的并发症情况。术后3个月检查两组患者单眼与双眼的离焦曲线及对比敏感度,并填写MIOL植入术后的满意度调查问卷。裸眼远视力、对比敏感度及满意度评分采用均数±标准差(x±s)进行描述。治疗前后的组内比较采用配对t检验,观察组与对照组的组间比较采用独立样本t检验,两组间术后并发症、视觉干扰及满意度调查的比较采用卡方检验。结果观察组与对照组术后角膜水肿、高眼压及黄斑囊样水肿等并发症发生率的比较,差异无统计学意义(χ~2=0,0.10,0.84;P>0.05)。所有患者术后裸眼远视力较术前均有明显改善,差异有统计学意义(t=1.97,P<0.05)。观察组与对照组患者术后均获得了满意的双眼远视力,二者差异无统计学意义(t=1.02,P>0.05)。对两组患者进行33 cm的近距离视力测试,对照组的裸眼视力较好,但组间差异无统计学意义(t=1.89,P>0.05)。对两组患者进行67 cm的中距离视力测试,观察组视力明显好于对照组,差异有统计学意义(t=2.35,P<0.05)。将观察组与对照组患者术后产生眩光、光晕及色差等视觉干扰现象的情况进行比较,差异均无统计学意义(χ~2=0.43,0.46,0.06;P>0.05)。在暗视状态下,观察组患者6c.d-1和12c.d-1空间频率的对比敏�
文摘AIM： To evaluate human lens epithelium cell apoptosis and epithelial to mesenchymal transition （EMT） induced by femtosecond laser in femtosecond laser assisted cataract surgery （FLACS）. METHODS： Sixty cataract patients with N2 to N3 stage according to the LOCS III were enrolled in this study and divided into three groups randomly： FLACSl group （cataract surgery by FLACS with LenSx）, FLACS2 group （cataract surgery by FLACS with LensAR） and manual group （cataract surgery by phacoemulsification）. Patients in two FLACS groups performed anterior capsulotomy by LenSx or LensAR laser system. Patients in the manual group were performed continuous curvilinear capsulorrhexis （CCC） manually. The anterior capsules were fixed right after moved out of eye. Hematoxylin-eosine staining, immunofluorescence staining and real-time PCR were performed in order to observe human lens epithelium cells changes after cataract surgery. RESULTS： The capsule cutting edge was shown irregularity and roughness in two FLACS groups and smooth edge in manual capsulotomy by pathologic staining. Irregularities of the cell configuration with partly swollen and destroyed nuclei were observed in two FLACS groups. Femtosecond laser could induce a significantly higher cell apoptosis in human lens epithelium cell than manually performed CCC （P〈0.05）. Lens epithelium cells apoptosis were correlated with femtosecond laser duration according to Pearson correlation analysis. Decreased N-cadherin expression, alpha-SMA and FSP-1 level in two FLACS groups showed the inhibition of cell EMT. CONCLUSION： Femtosecond laser may affect the apoptosis and EMT of lens epithelium cells which are under the peeled central lens capsule.
文摘AIM： To evaluate blood pressure（BP） changes during phacoemulsification（PC） and femtosecond laser（FSL）-assisted cataract surgery.METHODS： A retrospective chart review was performed for all patients who received traditional phacoemulsification surgery（PC group） and FSL-assisted cataract surgery（FS group） from July 2013 to December 2014. Totally 206 eyes from 133 patients receiving the two types of procedures were included.Patient characteristics（age, gender, and hypertension history）, pre- and post-operative BPs were collected.RESULTS： The pro-operative systolic and diastolic BPs（mm Hg） were 124.89 ±20.48 vs 126.98 ±16.85, and71.88 ±9.81 vs 73.56 ±10.03, in PC and FS groups,respectively. While the post-operative systolic and diastolic BPs（mm Hg） were 130.13 ±22.59 vs 134.77 ±17.52, and 73.41 ±11.62 vs 78.89 ±12.2, in PC and FS groups, respectively. Paired-sample t-tests showed obvious systolic and diastolic BP elevations in FS group after surgery（P =0.001 and 0.007） and no reliability in PC group（P =0.094 and 0.359）. A linear regression model revealed systolic and diastolic BP elevations,which were related to longer surgical times for FS group（P =0.008 and 0.021）. Age, gender, and hypertension history were not correlated with blood pressure elevation in either group.CONCLUSION： BP increases but at a limited level after FSL-assisted cataract surgery compared to traditional phacoemulsification
