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Permutation Test在假设检验中的应用 被引量:38
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作者 荀鹏程 赵杨 +3 位作者 易洪刚 柏建岭 于浩 陈峰 《数理统计与管理》 CSSCI 北大核心 2006年第5期616-621,共6页
本文介绍了一种实用的、基于大量计算的统计推断方法———Permutation test。该法根据所研究的问题构造检验统计量,并利用手头样本,按排列组合的原理导出检验统计量的理论抽样分布;若难以导出确切的理论分布,则采用抽样模拟的方法估计... 本文介绍了一种实用的、基于大量计算的统计推断方法———Permutation test。该法根据所研究的问题构造检验统计量,并利用手头样本,按排列组合的原理导出检验统计量的理论抽样分布;若难以导出确切的理论分布,则采用抽样模拟的方法估计其近似分布,然后求出从该分布中获得手头样本及更极端样本的概率(P值),并界定此概率值,作出推论。本方法属分布自由检验,适用于总体分布未知的小样本资料,以及某些难以用常规方法分析的资料之假设检验问题。本文就“Permutation”的含义,“Permutation tes”t的特点,“统计量的构造”,“模拟次数的选择”,应用进展等问题展开探讨。 展开更多
关键词 排列(组合)检验 确切概率 假设检验 分布自由
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配电网电容电流的准确预测 被引量:5
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作者 赵建文 侯媛彬 《电工电能新技术》 CSCD 北大核心 2008年第3期49-53,共5页
配电网电容电流的准确测量是消弧线圈调节、补偿消弧的前提。本文分析了现有电网电容电流检测方法的特点;提出了单相附加电阻预测故障接地电容电流的新方法;该方法通过测量单相附加电阻后的电网零序电压和接地电阻上的电压,就能在电网... 配电网电容电流的准确测量是消弧线圈调节、补偿消弧的前提。本文分析了现有电网电容电流检测方法的特点;提出了单相附加电阻预测故障接地电容电流的新方法;该方法通过测量单相附加电阻后的电网零序电压和接地电阻上的电压,就能在电网正常运行时准确预测出电网发生单相接地故障时的电容电流。设计了基于此新方法,利用DSP实现的智能型电容电流预测装置方案;利用模拟电网对装置预测的准确性进行了验证。结果表明,该系统不仅能准确预测电网发生单线接地故障时的电容电流、对地绝缘电阻电流、接地点的残流等影响熄弧的关键参数,还能检测谐振电网的补偿状态,且操作安全、测量迅速、简便易用。 展开更多
关键词 电容电流 准确预测 DSP 配电网 单相接地 序网络
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确切logistic回归方法及其医学遗传学应用 被引量:4
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作者 王彤 韩宏 《中国卫生统计》 CSCD 北大核心 2003年第3期147-150,共4页
目的 探讨确切logistic回归分析方法及其在医学遗传学领域的应用。 方法 利用确切logistic回归方法对医学遗传学实例进行分析。结果 确切logistic回归适用于解决样本量小、数据分布偏和不平衡的数据 ,并具有最大似然法logistic回归... 目的 探讨确切logistic回归分析方法及其在医学遗传学领域的应用。 方法 利用确切logistic回归方法对医学遗传学实例进行分析。结果 确切logistic回归适用于解决样本量小、数据分布偏和不平衡的数据 ,并具有最大似然法logistic回归不可比拟的稳定性。结论 确切logistic回归方法在医学遗传学领域具有良好的适用性。 展开更多
关键词 LOGISTIC回归分析 医学遗传学 确切概率 条件分布 实例分析
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Exact Tail Asymptotics for a Discrete-time Preemptive Priority Queue 被引量:1
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作者 Yang SONG Zai-ming LIU Hong-shuai DAI 《Acta Mathematicae Applicatae Sinica》 SCIE CSCD 2015年第1期43-58,共16页
In this paper, we consider a discrete-time preemptive priority queue with different service com- pletion probabilities for two classes of customers, one with high-priority and the other with low-priority. This model c... In this paper, we consider a discrete-time preemptive priority queue with different service com- pletion probabilities for two classes of customers, one with high-priority and the other with low-priority. This model corresponds to the classical preemptive priority queueing system with two classes of independent Poisson customers and a single exponential server. Due to the possibility of customers' arriving and departing at the same time in a discrete-time queue, the model considered in this paper is more complicated than the continuous- time model. In this model, we focus on the characterization of the exact tail asymptotics for the joint stationary distribution of the queue length of the two types of customers, for the two boundary distributions and for the two marginal distributions, respectively. By using generating functions and the kernel method, we get the exact tail asymptotic properties along the direction of the low-priority queue, as well as along the direction of the high-priority queue. 展开更多
关键词 discrete-time queue stationary distribution kernel method exact tail asymptotics
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Exact Distribution of Difference of Two Sample Proportions and Its Inferences 被引量:1
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作者 Keshab R. Dahal Mohamed Amezziane 《Open Journal of Statistics》 2020年第3期363-374,共12页
Comparing two population proportions using confidence interval could be misleading in many cases, such </span><span style="font-family:Verdana;">as</span><span style="font-family:Ve... Comparing two population proportions using confidence interval could be misleading in many cases, such </span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> the sample size </span><span style="font-family:Verdana;">being</span><span style="font-family:Verdana;"> small and the test </span><span style="font-family:Verdana;">being</span><span style="font-family:Verdana;"> based on normal approximation. In this case, the only </span><span style="font-family:Verdana;">one</span><span style="font-family:Verdana;"> option that we have is to collect a large sample. Unfortunately, the large sample might not be possible. One example is a person suffering from a rare disease. The main purpose of this journal is to derive a closed formula for the exact distribution of the difference between two independent sample proportions, and use it to perform related inferences such as a confidence interval, regardless of the sample sizes and compare with the existing Wald, Agresti-Caffo </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> Score. In this journal, we have derived a closed formula for the exact distribution of the difference between two independent sample proportions. This distribution doesn’t need any </span><span style="font-family:Verdana;">requirements,</span><span style="font-family:Verdana;"> and can be used to perform inferences such </span><span style="font-family:Verdana;">as:</span><span style="font-family:Verdana;"> a hypothesis test for two population proportions, regardless of the nature of the distribution and the sample sizes. We claim </span><span style="font-family:Verdana;">that</span><span style="font-family:Verdana;"> exact distribution has the </span><span style="font-family:Verdana;">least</span><span style="font-family:Verdana;"> confidence width among Wald, Agresti-Caffo </span><span style="font-family:Verdana;">and</span><span style="font-family:Verdana;"> Score, so it is suitable for inferences of the difference between the pop 展开更多
关键词 Statistical Inferences exact distribution Difference of Sample Proportions
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Symmetrical Independence Tests for Two Random Vectors with Arbitrary Dimensional Graphs
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作者 Jia Min LIU Gao Rong LI +1 位作者 Jian Qiang ZHANG Wang Li XU 《Acta Mathematica Sinica,English Series》 SCIE CSCD 2022年第4期662-682,共21页
Test of independence between random vectors X and Y is an essential task in statistical inference.One type of testing methods is based on the minimal spanning tree of variables X and Y.The main idea is to generate the... Test of independence between random vectors X and Y is an essential task in statistical inference.One type of testing methods is based on the minimal spanning tree of variables X and Y.The main idea is to generate the minimal spanning tree for one random vector X,and for each edges in minimal spanning tree,the corresponding rank number can be calculated based on another random vector Y.The resulting test statistics are constructed by these rank numbers.However,the existed statistics are not symmetrical tests about the random vectors X and Y such that the power performance from minimal spanning tree of X is not the same as that from minimal spanning tree of Y.In addition,the conclusion from minimal spanning tree of X might conflict with that from minimal spanning tree of Y.In order to solve these problems,we propose several symmetrical independence tests for X and Y.The exact distributions of test statistics are investigated when the sample size is small.Also,we study the asymptotic properties of the statistics.A permutation method is introduced for getting critical values of the statistics.Compared with the existing methods,our proposed methods are more efficient demonstrated by numerical analysis. 展开更多
关键词 exact distribution minimal spanning tree asymptotic distribution symmetrical independence test
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一类上界型拟合优度检验统计量的精确分布 被引量:1
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作者 张军舰 李国英 赵志源 《应用概率统计》 CSCD 北大核心 2009年第4期421-432,共12页
对于简单假设的拟合优度检验,Zhang(2002)构造出一类上界型检验.取不同的参数λ和不同的权函数q(t),这类检验包含了Kolmogorov-Smirov检验,Berk andJones(1979)检验等已有的上界型检验.文献中仅对极少数λ和q(t)所对应的检验给出了零假... 对于简单假设的拟合优度检验,Zhang(2002)构造出一类上界型检验.取不同的参数λ和不同的权函数q(t),这类检验包含了Kolmogorov-Smirov检验,Berk andJones(1979)检验等已有的上界型检验.文献中仅对极少数λ和q(t)所对应的检验给出了零假设下的精确分布.然而,针对不同的问题,"好"的检验是不同的,因此有必要对任意给定的λ和q(t)情况,讨论该类检验.本文对任意给定的λ和q(t)≡1情况,导出了相应上界型检验统计量在零假设下的精确分布.当样本容量n较大时,精确分布的计算时间较长,本文还通过模拟比较得到了在不同样本量下,应采用的计算方法.最后,给出一个实际例子对前述方法加以简单说明. 展开更多
关键词 精确分布 广义非参似然比 拟合优度检验
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Aerosol transportation in horizontal channels w让h gravitational effects 被引量:1
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作者 Yongwei Gao Ke Zhong Yanming Kang 《Particuology》 SCIE EI CAS CSCD 2019年第3期159-168,共10页
Aerosol particle deposition in a narrow horizontal channel with gravitational effects is studied in the laminar flow regime. A general explic让 solution for predicting the aerosol transportation in the channel is obta... Aerosol particle deposition in a narrow horizontal channel with gravitational effects is studied in the laminar flow regime. A general explic让 solution for predicting the aerosol transportation in the channel is obtained theoretically. The characteristics of the asymmetric concentratio n profiles and their dependence on gravitational settling are analyzed for different settings of the diffusion and sedimentation parameters. Aerosol deposition on the channel walls, which is influenced by a combination of mechanisms, is also analyzed. The results are compared with those from simplified models obtained in previous studies in which only diffusion or gravity was considered. The analysis reveals that the literature results regarding this aspect may be simplified with the present solution under specific conditions. 展开更多
关键词 exact solution Combined DEPOSITION GRAVITATIONAL effect HORIZONTAL channel ASYMMETRIC distribution
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库特(Couette)剪切流准确解的一般形式 被引量:1
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作者 韩德才 周铁农 潘永阁 《高压物理学报》 CAS CSCD 北大核心 2000年第3期229-234,共6页
从N S方程出发 ,得到了轴对称异型断面管纯剪切流动速度分布的一般解 ,进而推出了纯剪切流动有限宽度矩形断面管的速度分布和流量计算公式 ,证明了库特剪切流是有限宽度矩形断面管当宽度趋向无穷大时的一种特例。并对库特剪切流流量的... 从N S方程出发 ,得到了轴对称异型断面管纯剪切流动速度分布的一般解 ,进而推出了纯剪切流动有限宽度矩形断面管的速度分布和流量计算公式 ,证明了库特剪切流是有限宽度矩形断面管当宽度趋向无穷大时的一种特例。并对库特剪切流流量的计算误差进行了分析 ,给出了该公式的适用范围 ,同时对有限宽度矩形断面管剪切流公式进行了曲线拟合 ,得到了便于工程使用的流量计算公式。 展开更多
关键词 库特剪切流 准确解 速度分布
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Stationary distributions for two-dimensional sticky Brownian motions:Exact tail asymptotics and extreme value distributions
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作者 Hongshuai Dai Yiqiang Q.Zhao 《Science China Mathematics》 SCIE CSCD 2021年第11期2539-2562,共24页
Sticky Brownian motions can be viewed as time-changed semimartingale reflecting Brownian motions,which find applications in many areas including queueing theory and mathematical finance.In this paper,we focus on stati... Sticky Brownian motions can be viewed as time-changed semimartingale reflecting Brownian motions,which find applications in many areas including queueing theory and mathematical finance.In this paper,we focus on stationary distributions for sticky Brownian motions.Main results obtained here include tail asymptotic properties in the marginal distributions and joint distributions.The kernel method,copula concept and extreme value theory are the main tools used in our analysis. 展开更多
关键词 sticky Brownian motion queueing model stationary distribution exact tail asymptotic kernel method extreme value distribution
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SUR模型参数估计量的精确分布
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作者 滕成业 陈图豪 方宏彬 《中山大学学报(自然科学版)》 CAS CSCD 1990年第3期31-36,共6页
将指数函数的矩阵分式算子的结论,推广到无穷可微函数的情形。利用此结论,导出扰动项遵循第三类椭球等高分布的SUR模型估计量的精确分布,并推广了 Phillips(1985)的结果。
关键词 SUR模型 精确分布 椭球等高分布
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Ground and Low-Lying Collective States of Rotating Three-Boson System
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作者 Mohd.Imran M.A.H.Ahsan 《Communications in Theoretical Physics》 SCIE CAS CSCD 2016年第4期473-482,共10页
The ground and low-lying collective states of a rotating system of N=3 bosons harmonically confined in quasi-two-dimension and interacting via repulsive finite-range Gaussian potential is studied in weakly to moderate... The ground and low-lying collective states of a rotating system of N=3 bosons harmonically confined in quasi-two-dimension and interacting via repulsive finite-range Gaussian potential is studied in weakly to moderately interacting regime.The N-body Hamiltonian matrix is diagonalized in subspaces of quantized total angular momenta 0 ≤ L ≤ 4N to obtain the ground and low-lying eigenstates.Our numerical results show that breathing modes with N-body eigenenergy spacing of 2hω⊥,known to exist in strictly 2D system with zero-range(δ-function) interaction potential,may as well exist in quasi-2D system with finite-range Gaussian interaction potential.To gain an insight into the many-body states,the von Neumann entropy is calculated as a measure of quantum correlation and the conditional probability distribution is analyzed for the internal structure of the eigenstates.In the rapidly rotating regime the ground state in angular momentum subspaces L=(q/2)N(N-1) with q=2,4 is found to exhibit the anticorrelation structure suggesting that it may variationally be described by a Bose–Laughlin like state.We further observe that the first breathing mode exhibits features similar to the Bose–Laughlin state in having eigenenergy,von Neumann entropy and internal structure independent of interaction for the three-boson system considered here.On the contrary,for eigenstates lying between the Bose–Laughlin like ground state and the first breathing mode,values of eigenenergy,von Neumann entropy and internal structure are found to vary with interaction. 展开更多
关键词 Bose–Einstein condensation exact diagonalization breathing mode Bose–Laughlin state von Neumann entropy conditional probability distribution
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基于精确Zoeppritz方程的非线性AVO三参数反演 被引量:13
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作者 周林 李景叶 陈小宏 《地球物理学报》 SCIE EI CAS CSCD 北大核心 2016年第7期2663-2673,共11页
常规AVO三参数反演通常存在密度反演不准确的问题,而密度参数对常规油气藏中的流体识别、流体饱和度计算、孔隙度计算以及非常规油气藏中TOC含量计算、裂缝预测等都至关重要,因此对于研究如何利用大偏移距振幅信息和富含密度信息的PS波... 常规AVO三参数反演通常存在密度反演不准确的问题,而密度参数对常规油气藏中的流体识别、流体饱和度计算、孔隙度计算以及非常规油气藏中TOC含量计算、裂缝预测等都至关重要,因此对于研究如何利用大偏移距振幅信息和富含密度信息的PS波地震资料来提高密度反演结果的稳定性和精度显得尤为重要.研究基于贝叶斯反演理论框架,引入三变量Cauchy分布先验约束,利用精确Zoeppritz方程构建了AVO三参数联合反演的目标函数,对目标函数进行Taylor二阶非线性简化,得到模型参数的迭代更新公式,实现了大偏移距地震振幅信息的利用和PP波、PS波联合反演.合成数据和实际地震数据的方法测试结果表明,新方法不仅可以直接反演纵波速度、横波速度和密度,而且还具有很高的精度,尤其是密度反演结果.基于合成数据的PP波、PS波单独反演结果与PP波和PS波联合反演结果对比显示,联合反演稳定性更好,精度更高,抗噪能力更强,验证了该方法的可行性和有效性.与基于Aki-Richards近似公式的反演结果对比表明,该反演方法具有更高的反演精度和更好的抗噪性. 展开更多
关键词 精确Zoeppritz方程 贝叶斯 三变量柯西分布 非线性 联合反演
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基于黏弹性解的土层地震反应分析程序LSSRLI-1和SHAKE2000的对比 被引量:8
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作者 李瑞山 袁晓铭 李程程 《地震工程与工程振动》 CSCD 北大核心 2015年第3期17-27,共11页
地震过程中震动传播的局部场地效应通常用一维的场地反应分析方法来考虑,目前使用最多的是线性、等效线性化和非线性三类,其中国内外分别以LSSRLI-1和SHAKE2000为代表的等效线性化程序使用最为广泛。LSSRLI-1是我国地震安全评价程序,提... 地震过程中震动传播的局部场地效应通常用一维的场地反应分析方法来考虑,目前使用最多的是线性、等效线性化和非线性三类,其中国内外分别以LSSRLI-1和SHAKE2000为代表的等效线性化程序使用最为广泛。LSSRLI-1是我国地震安全评价程序,提出已有20多年,为我国的防震减灾事业做出了巨大贡献,但也在实践过程中表现出了一些缺点和不足,是否可以改进有待研究。本文以经典波动理论为基础编制了相应的土层反应分析线性计算程序,并与LSSRLI-1和SHAKE2000就硬和软两种场地上地表加速度反应谱和土体剪应变分布进行了对比分析,考虑了不同输入波以及不同震动强度对分析结果的影响,也讨论了土体剪应变计算偏差对地表反应谱的影响。结果表明:硬和软场地上SHAKE2000计算出地表加速度反应谱和土体剪应变分布均符合较好;硬和软场地上传递函数计算中LSSRLI-1、SHAKE2000和精确解三者一致;硬场地上LSSRLI-1计算所得土体剪应变分布同SHAKE2000和精确解相比偏差很小且对反应谱的影响可以忽略;某些情况下,软场地上LSSRLI-1计算出的土体剪应变分布同SHAKE2000和精确解相比明显偏大,该偏差会导致地表响应显著偏小,说明LSSRLI-1用于软场地地震反应分析时其剪应变求解方法有待改进。 展开更多
关键词 地震反应分析 等效线性化 精确解 地表反应谱 土体剪应变分布
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Explicit Exact Solution of Damage Probability for Multiple Weapons against a Unitary Target 被引量:4
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作者 Hongyun Wang Cardy Moten +2 位作者 Morris Driels Don Grundel Hong Zhou 《American Journal of Operations Research》 2016年第6期450-467,共18页
Abstract We study the damage probability when M weapons are used against a unitary target. We use the Carleton damage function to model the distribution of damage probability caused by each weapon. The deviation of th... Abstract We study the damage probability when M weapons are used against a unitary target. We use the Carleton damage function to model the distribution of damage probability caused by each weapon. The deviation of the impact point from the aimpoint is attributed to both the dependent error and independent errors. The dependent error is one random variable affecting M weapons the same way while independent errors are associated with individual weapons and are independent of each other. We consider the case where the dependent error is significant, non-negligible relative to independent errors. We first derive an explicit exact solution for the damage probability caused by M weapons for any M. Based on the exact solution, we find the optimal aimpoint distribution of M weapons to maximize the damage probability in several cases where the aimpoint distribution is constrained geometrically with a few free parameters, including uniform distributions around a circle or around an ellipse. Then, we perform unconstrained optimization to obtain the overall optimal aimpoint distribution and the overall maximum damage probability, which is carried out for different values of M, up to 20 weapons. Finally, we derive a phenomenological approximate expression for the damage probability vs. M, the number of weapons, for the parameters studied here. 展开更多
关键词 Damage Probability Carleton Damage Function Multiple Weapons with Dependent Errors exact Solution Optimal distribution of Aimpoint
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基于精确特征分布匹配和多域信息融合的跨域行人重识别 被引量:1
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作者 杨真真 邵静 +1 位作者 杨永鹏 吴心怡 《信号处理》 CSCD 北大核心 2023年第6期1099-1107,共9页
无监督域自适应行人重识别(Unsupervised Domain Adaptation for person Re-identification, UDA-ReID)任务致力于将知识从已标记的源域数据转移到目标域。和传统的单源域自适应相比,将多源域的知识迁移到目标域是一项更具挑战性的任务... 无监督域自适应行人重识别(Unsupervised Domain Adaptation for person Re-identification, UDA-ReID)任务致力于将知识从已标记的源域数据转移到目标域。和传统的单源域自适应相比,将多源域的知识迁移到目标域是一项更具挑战性的任务。由于领域上的差距,多数据集的简单组合只能产生有限的改进。针对此问题,提出了一种基于精确特征分布匹配和多域信息融合的多源域对比学习(exact feature distribution Matching and multi-domain information Fusion based Multi-domain Contrastive Learning, MFMCL)方法。该方法首先采用具有混合记忆的自步对比学习提取不同域数据的特征,并对提取到的特征进行构图,然后通过两层残差图卷积网络进行多域特征融合。其次,为了增强交叉分布特征、产生更丰富的信息,通过基于排序算法的精确直方图匹配来实现精确特征分布匹配,以获得更多样化的特征增强。实验表明,与目前先进的无监督域自适应行人重识别方法相比,所提出的MFMCL方法在广泛使用的行人重识别数据集Market1501、MSMT17和Duke上都取得了优越的性能。 展开更多
关键词 行人重识别 无监督域自适应 精确特征分布匹配 多域信息融合 图卷积网络
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基于双重注意力与精确特征分布匹配的车辆重识别
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作者 徐岩 潘旭光 +1 位作者 郭晓燕 刘香兰 《计算机工程与应用》 CSCD 北大核心 2023年第23期114-124,共11页
为了解决目前车辆重识别方法细粒度特征提取能力弱、域泛化能力差的问题,提出了一种基于双重注意力与精确特征分布匹配的车辆重识别方法。提出一种新的双重注意力机制,使用WideResNet50与双重注意力模块构建多细粒度特征提取网络的前置... 为了解决目前车辆重识别方法细粒度特征提取能力弱、域泛化能力差的问题,提出了一种基于双重注意力与精确特征分布匹配的车辆重识别方法。提出一种新的双重注意力机制,使用WideResNet50与双重注意力模块构建多细粒度特征提取网络的前置部分,用于高效建模全局上下文信息并增强对车辆细粒度特征的提取能力。将基于精确特征分布匹配的风格迁移策略融入浅层主干来增强源域的域多样性,实现数据增广,从而有效提升车辆重识别的跨域性能和特征表达能力。提出了一种逐深度多尺度特征金字塔结构来加强特征提取,整合不同尺度特征层的多层次信息,并将该结构输出的车辆特征采用特征图分割的思想来突出局部细粒度信息,提升模型对车辆细粒度信息的敏感度。引入Tuplet边际损失来缓解最困难样本的过拟合问题。在两个大型基准车辆数据集VeRi-776和VehicleID上的实验结果表明,所提出算法在单域和跨域任务上都具有较好的重识别效果。 展开更多
关键词 双重注意力机制 精确特征分布匹配 多尺度特征金字塔 车辆重识别 深度学习
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Minimum Exact Cover Problem of Group Key Distribution 被引量:2
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作者 FU Xiong1,2, XU Shouzhi3 1. School of Law ,Wuhan University, Wuhan 430072, Hubei, China 2. Department of Technology, Guangzhou Luogang District People’s Court, Guangzhou 510730, Guangdong, China 3. College of Electronic Engineering and Information Technology, China Three Gorges University, Yichang 443002, Hubei, China 《Wuhan University Journal of Natural Sciences》 CAS 2009年第2期137-142,共6页
Secure group communications are restrained by the number of the group size, number of changes and their distribution, all existing works do not meet the commands of applications with large group size and high dynamic ... Secure group communications are restrained by the number of the group size, number of changes and their distribution, all existing works do not meet the commands of applications with large group size and high dynamic members. In this paper, minimum exact cover problem for group key distribution (GMECP) is presented, and a heuristic solution is testified. Then an algorithm of batch rekeying with renewing cost tending to zero is illustrated, which can process any large number of change requests with best security guaranteed. Efficiency analysis and simulation test show that the achievement can improve the efficiency of any tree-based group key management. 展开更多
关键词 minimum exact cover problem group key distribution secure multicast group key management
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基于RNA-seq数据的差异基因和异构体检测 被引量:2
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作者 王黎黎 刘学军 张礼 《南京大学学报(自然科学版)》 CAS CSCD 北大核心 2016年第2期253-260,共8页
基因和异构体表达水平的差异检测是获取基因和异构体功能的重要途径,目前差异检测已经是转录组研究中一个重要的研究方向.RNA-seq技术近年来被广泛用于差异基因的检测.为模拟读段的非均匀分布,通常采用负二项分布对读段计数进行建模.现... 基因和异构体表达水平的差异检测是获取基因和异构体功能的重要途径,目前差异检测已经是转录组研究中一个重要的研究方向.RNA-seq技术近年来被广泛用于差异基因的检测.为模拟读段的非均匀分布,通常采用负二项分布对读段计数进行建模.现存的负二项分布模型大都是直接对基因读段计数进行建模,不能进行差异异构体检测.提出基于PGseq模型计算出的基因和异构体表达水平的负二项分布模型,采用exact test方法进行差异分析,解决了异构体的差异检测的问题.经实验验证,该方法在基因和异构体两方面的差异检测中都具有较高的准确度和灵敏度. 展开更多
关键词 RNA-SEQ 差异基因 差异异构体 负二项分布 exact TEST
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An Exact Generalized Test for Homogeneity of Inverse Gaussian Scale Parameters
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作者 Xu-hua LIU Xing-zhong XU Wei-yan MU 《Acta Mathematicae Applicatae Sinica》 SCIE CSCD 2019年第4期761-769,共9页
In this paper, we propose a new generalized p-value for testing homogeneity of scale parameters λi from k independent inverse Gaussian populations. The proposed generalized p-value is proved to have exact frequentist... In this paper, we propose a new generalized p-value for testing homogeneity of scale parameters λi from k independent inverse Gaussian populations. The proposed generalized p-value is proved to have exact frequentist property, and it is also invariant under the group of scale transformation. Simulation results indicate that the proposed test is better than existing approximate χ^2 test. 展开更多
关键词 INVERSE GAUSSIAN distribution Generalized P-VALUE exact frequentist PROPERTY
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