Traditional Chinese text retrieval systems return a ranked list of documentsin response to a user''s request. While a ranked list of documents may be an appropriate response forthe user, frequently it is not. ...Traditional Chinese text retrieval systems return a ranked list of documentsin response to a user''s request. While a ranked list of documents may be an appropriate response forthe user, frequently it is not. Usually it would be better for the system to provide the answeritself instead of requiring the user to search for the answer in a set of documents. Since Chinesetext retrieval has just been developed lately, and due to various specific characteristics ofChinese language, the approaches to its retrieval are quite different from those studies andresearches proposed to deal with Western language. Thus, an architecture that augments existingsearch engines is developed to support Chinese natural language question answering. In this paper anew approach to building Chinese question-answering system is described, which is thegeneral-purpose, fully-automated Chinese quest ion-answering system available on the web. In theapproach, we attempt to represent Chinese text by its characteristics, and try to convert theChinese text into ERE (E: entity, R: relation) relation data lists, and then to answer the questionthrough ERE relation model. The system performs quite well giving the simplicity of the techniquesbeing utilized. Experimental results show that question-answering accuracy can be greatly improvedby analyzing more and more matching ERE relation data lists. Simple ERE relation data extractiontechniques work well in our system making it efficient to use with many backend retrieval engines.展开更多
The estrogen receptor （ER）-related factor （ERRF） was previously reported as a novel modulator of breast cancer （Suet al., 2012）. Its expression was upregulated in breast cancer, and increased ERRF expression was...The estrogen receptor （ER）-related factor （ERRF） was previously reported as a novel modulator of breast cancer （Suet al., 2012）. Its expression was upregulated in breast cancer, and increased ERRF expression was significantly associated with ER and/or progesterone receptor （PR） positivity and human epidermal growth factor receptor 2 （HER2） negativity （Suet al., 2012）. In addition, ERRF was necessary for ER-positive breast cancer cells to form tumors in nude mice （Suet al., 2012）. Unexpectedly,展开更多
The objective was to investigate the estrogenic effects of Plantaginis Semen aqueous extracts and study the mechanism of action.Mouse uterine weight test and MCF-7cell proliferation assay were used to evaluate the est...The objective was to investigate the estrogenic effects of Plantaginis Semen aqueous extracts and study the mechanism of action.Mouse uterine weight test and MCF-7cell proliferation assay were used to evaluate the estrogenic effects of Plantaginis Semen aqueous extracts.Reporter gene assay were adopted to explore the mechanism展开更多
Low hip bone mineral density(BMD)is an important index for osteoporosis and is associated with hip fracture,which leads to more cases of disability and mortality than all other kinds of fractures(Kanis et al.,2007).BM...Low hip bone mineral density(BMD)is an important index for osteoporosis and is associated with hip fracture,which leads to more cases of disability and mortality than all other kinds of fractures(Kanis et al.,2007).BMD’s heritability is more than 60%(Arden et al.,1996).A number of candidate loci for BMD have been previously identified by Genome Wide Association Studies(GWAS)(Xiong et al.,2009;Karasik et al.,2010;Zhang et al.,2013).Nevertheless,many significant signals based on GWAS are展开更多
文摘Traditional Chinese text retrieval systems return a ranked list of documentsin response to a user''s request. While a ranked list of documents may be an appropriate response forthe user, frequently it is not. Usually it would be better for the system to provide the answeritself instead of requiring the user to search for the answer in a set of documents. Since Chinesetext retrieval has just been developed lately, and due to various specific characteristics ofChinese language, the approaches to its retrieval are quite different from those studies andresearches proposed to deal with Western language. Thus, an architecture that augments existingsearch engines is developed to support Chinese natural language question answering. In this paper anew approach to building Chinese question-answering system is described, which is thegeneral-purpose, fully-automated Chinese quest ion-answering system available on the web. In theapproach, we attempt to represent Chinese text by its characteristics, and try to convert theChinese text into ERE (E: entity, R: relation) relation data lists, and then to answer the questionthrough ERE relation model. The system performs quite well giving the simplicity of the techniquesbeing utilized. Experimental results show that question-answering accuracy can be greatly improvedby analyzing more and more matching ERE relation data lists. Simple ERE relation data extractiontechniques work well in our system making it efficient to use with many backend retrieval engines.
文摘The estrogen receptor （ER）-related factor （ERRF） was previously reported as a novel modulator of breast cancer （Suet al., 2012）. Its expression was upregulated in breast cancer, and increased ERRF expression was significantly associated with ER and/or progesterone receptor （PR） positivity and human epidermal growth factor receptor 2 （HER2） negativity （Suet al., 2012）. In addition, ERRF was necessary for ER-positive breast cancer cells to form tumors in nude mice （Suet al., 2012）. Unexpectedly,
文摘The objective was to investigate the estrogenic effects of Plantaginis Semen aqueous extracts and study the mechanism of action.Mouse uterine weight test and MCF-7cell proliferation assay were used to evaluate the estrogenic effects of Plantaginis Semen aqueous extracts.Reporter gene assay were adopted to explore the mechanism
基金partially supported by or benefited from grants from NIH (P50AR055081,R01AG026564,R01AR050496,R01AR059781,D43TW009107,P20GM109036,R01GM109068,R01MH104680,R01MH107354,R01AR057049,and R03TW008221)
文摘Low hip bone mineral density(BMD)is an important index for osteoporosis and is associated with hip fracture,which leads to more cases of disability and mortality than all other kinds of fractures(Kanis et al.,2007).BMD’s heritability is more than 60%(Arden et al.,1996).A number of candidate loci for BMD have been previously identified by Genome Wide Association Studies(GWAS)(Xiong et al.,2009;Karasik et al.,2010;Zhang et al.,2013).Nevertheless,many significant signals based on GWAS are
