Studies on plant peroxidases are reviewed in this paper, including enzyme types and localization, molecular structure, purification and identification and gene expression and regulation related to plant growth, develo...Studies on plant peroxidases are reviewed in this paper, including enzyme types and localization, molecular structure, purification and identification and gene expression and regulation related to plant growth, development, wounding and pathogen infection etc. The physiological functions of peroxida ses in plant are also discussed, which cover such as active oxygen metabolism, formation of lignin and suberin, degradation of auxin, oxidation of other compounds and responses for various environmental stresses, especially the pathogen attack.展开更多
New advances in molecular biology of plant secondary metabolic pathway were summarized. The biosynthesis of artemisinin was used as an example, combined with the research work in the authors’ laboratory. Some new way...New advances in molecular biology of plant secondary metabolic pathway were summarized. The biosynthesis of artemisinin was used as an example, combined with the research work in the authors’ laboratory. Some new ways for producing plant secondary metabolites were proposed.展开更多
Amino acids have various prominent functions in plants. Besides their usage during protein biosynthesis, they also represent building blocks for several other biosynthesis pathways and play pivotal roles during signal...Amino acids have various prominent functions in plants. Besides their usage during protein biosynthesis, they also represent building blocks for several other biosynthesis pathways and play pivotal roles during signaling processes as well as in plant stress response. In general, pool sizes of the 20 amino acids differ strongly and change dynamically depending on the developmental and physiological state of the plant cell. Besides amino acid biosynthesis, which has already been investigated in great detail, the catabolism of amino acids is of central importance for adjusting their pool sizes but so far has drawn much less attention. The degradation of amino acids can also contribute substantially to the energy state of plant cells under certain physiological conditions, e.g. carbon starvation. In this review, we discuss the biological role of amino acid catabolism and summarize current knowledge on amino acid degradation pathways and their regulation in the context of plant cell physiology.展开更多
We reported in this manuscript that TGF-beta1 induces apoptosis in AML12 murine hepatocytes, which is associated with the activation of p38 MAPK signaling pathway. SB202190, a specific inhibitor of p38 MAPK, strongly ...We reported in this manuscript that TGF-beta1 induces apoptosis in AML12 murine hepatocytes, which is associated with the activation of p38 MAPK signaling pathway. SB202190, a specific inhibitor of p38 MAPK, strongly inhibited the TGF-beta1-induced apoptosis and PAI-1 promoter activity. Treatment of cells with TGF-beta1 activates p38. Furthermore, over-expression of dominant negative mutant p38 also reduced the TGF-beta1-induced apoptosis. The data indicate that the activation of p38 is involved in TGF-beta1-mediated gene expression and apoptosis.展开更多
文摘Studies on plant peroxidases are reviewed in this paper, including enzyme types and localization, molecular structure, purification and identification and gene expression and regulation related to plant growth, development, wounding and pathogen infection etc. The physiological functions of peroxida ses in plant are also discussed, which cover such as active oxygen metabolism, formation of lignin and suberin, degradation of auxin, oxidation of other compounds and responses for various environmental stresses, especially the pathogen attack.
文摘New advances in molecular biology of plant secondary metabolic pathway were summarized. The biosynthesis of artemisinin was used as an example, combined with the research work in the authors’ laboratory. Some new ways for producing plant secondary metabolites were proposed.
文摘Amino acids have various prominent functions in plants. Besides their usage during protein biosynthesis, they also represent building blocks for several other biosynthesis pathways and play pivotal roles during signaling processes as well as in plant stress response. In general, pool sizes of the 20 amino acids differ strongly and change dynamically depending on the developmental and physiological state of the plant cell. Besides amino acid biosynthesis, which has already been investigated in great detail, the catabolism of amino acids is of central importance for adjusting their pool sizes but so far has drawn much less attention. The degradation of amino acids can also contribute substantially to the energy state of plant cells under certain physiological conditions, e.g. carbon starvation. In this review, we discuss the biological role of amino acid catabolism and summarize current knowledge on amino acid degradation pathways and their regulation in the context of plant cell physiology.
基金grants fromthe Chinese Academy of Sciences (No. KJ951-BI608), the National Natural Sciences FOundation ofChina (No. 39625007 and
文摘We reported in this manuscript that TGF-beta1 induces apoptosis in AML12 murine hepatocytes, which is associated with the activation of p38 MAPK signaling pathway. SB202190, a specific inhibitor of p38 MAPK, strongly inhibited the TGF-beta1-induced apoptosis and PAI-1 promoter activity. Treatment of cells with TGF-beta1 activates p38. Furthermore, over-expression of dominant negative mutant p38 also reduced the TGF-beta1-induced apoptosis. The data indicate that the activation of p38 is involved in TGF-beta1-mediated gene expression and apoptosis.
