In the past decades, enzyme mimetics based on ceria nanoparticles （nanoceria） have been developed as potential substitutes for nature enzymes. The mixed valence states of cerium and the patterns of oxygen vacancies ...In the past decades, enzyme mimetics based on ceria nanoparticles （nanoceria） have been developed as potential substitutes for nature enzymes. The mixed valence states of cerium and the patterns of oxygen vacancies on crystal planes result in different enzyme mimetic activities. In this review we survey the bio-applications of nanoceria-based enzyme mimetics as well as the underlying mechanisms. Factors influencing the enzyme mimetic activities and future perspective of nanoceria-based enzyme mimetics are also addressed.展开更多
A simple and efficient colorimetric biosensing for hydrogen peroxide and glucose with peroxidase-like vitamin C（Vc） functionalized Fe3O4 magnetic nanoparticles（Vc/Fe3O4MNPs） as a catalyst is reported. Compared wit...A simple and efficient colorimetric biosensing for hydrogen peroxide and glucose with peroxidase-like vitamin C（Vc） functionalized Fe3O4 magnetic nanoparticles（Vc/Fe3O4MNPs） as a catalyst is reported. Compared with Fe3O4 MNPs and other catalysts, Vc/Fe3O4 MNPs exhibited superior catalytic properties. Kinetic studies indicated that vitamin C incorporated on Fe3O4 MNPs improved the affinity toward H2O2. As low as 0,29 μmol/L H2O2 can be detected with a wide linear range of 0.5-100 μmol/L H2O2; moreover, as low as 0.288 μmol/L glucose can be detected with a linear range of 0.5-25 μmol/L glucose. The detection method was highly sensitive in sensing H2O2 and glucose. The robustness of Vc/Fe3O4 MNPs rendered them suitable for wide ranging applications.展开更多
通过水热法合成了氧化铽纳米材料,并将合成的氧化铽纳米材料进行了TEM和XRD表征,同时研究了氧化铽对氧气氧化3,3’,5,5’-四甲基联苯二胺(TMB)发生显色反应的催化性能,并研究了类酶催化反应的动力学特征,得到米氏常数(Km)为0.123 m M和...通过水热法合成了氧化铽纳米材料,并将合成的氧化铽纳米材料进行了TEM和XRD表征,同时研究了氧化铽对氧气氧化3,3’,5,5’-四甲基联苯二胺(TMB)发生显色反应的催化性能,并研究了类酶催化反应的动力学特征,得到米氏常数(Km)为0.123 m M和最大反应速率(Vm)为2.6×10-6 M·s-1。探究了氧化铽氧化TMB的催化机理,可能是由于氧化铽表面的晶格氧导致其催化氧气氧化TMB。展开更多
文摘In the past decades, enzyme mimetics based on ceria nanoparticles （nanoceria） have been developed as potential substitutes for nature enzymes. The mixed valence states of cerium and the patterns of oxygen vacancies on crystal planes result in different enzyme mimetic activities. In this review we survey the bio-applications of nanoceria-based enzyme mimetics as well as the underlying mechanisms. Factors influencing the enzyme mimetic activities and future perspective of nanoceria-based enzyme mimetics are also addressed.
文摘A simple and efficient colorimetric biosensing for hydrogen peroxide and glucose with peroxidase-like vitamin C（Vc） functionalized Fe3O4 magnetic nanoparticles（Vc/Fe3O4MNPs） as a catalyst is reported. Compared with Fe3O4 MNPs and other catalysts, Vc/Fe3O4 MNPs exhibited superior catalytic properties. Kinetic studies indicated that vitamin C incorporated on Fe3O4 MNPs improved the affinity toward H2O2. As low as 0,29 μmol/L H2O2 can be detected with a wide linear range of 0.5-100 μmol/L H2O2; moreover, as low as 0.288 μmol/L glucose can be detected with a linear range of 0.5-25 μmol/L glucose. The detection method was highly sensitive in sensing H2O2 and glucose. The robustness of Vc/Fe3O4 MNPs rendered them suitable for wide ranging applications.
文摘通过水热法合成了氧化铽纳米材料,并将合成的氧化铽纳米材料进行了TEM和XRD表征,同时研究了氧化铽对氧气氧化3,3’,5,5’-四甲基联苯二胺(TMB)发生显色反应的催化性能,并研究了类酶催化反应的动力学特征,得到米氏常数(Km)为0.123 m M和最大反应速率(Vm)为2.6×10-6 M·s-1。探究了氧化铽氧化TMB的催化机理,可能是由于氧化铽表面的晶格氧导致其催化氧气氧化TMB。
