目的探讨症状性动脉粥样硬化性颅内动脉长节段闭塞患者血管成形术中置入37mm长Enterprise支架治疗的效果和安全性。方法 27例症状性颅内动脉粥样硬化性长节段闭塞患者,术中亚满意球囊扩张后采用37 mm长Enterprise支架行血管成形术。记...目的探讨症状性动脉粥样硬化性颅内动脉长节段闭塞患者血管成形术中置入37mm长Enterprise支架治疗的效果和安全性。方法 27例症状性颅内动脉粥样硬化性长节段闭塞患者,术中亚满意球囊扩张后采用37 mm长Enterprise支架行血管成形术。记录手术情况,术后30d行改良Rankin量表(modified Rankin scale,mRS)评分评定治疗效果;比较术前1d及术后3、30d美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)评分;观察术后30d神经系统并发症发生情况;随访3～12个月,行数字减影血管造影或CT血管造影,观察管腔再狭窄发生情况。结果 3例微导丝未通过闭塞段,24例成功置入支架、血管再通,置入支架后管腔残余狭窄率为(19.2±6.9)%;术后30d治疗效果为优10例,良9例,差5例;术后3、30dNIHSS评分[(8.2±2.0)、(6.1±1.9)分]均较术前[(10.6±2.2)分]降低(P<0.05);术后30d内发生缺血性脑卒中1例,造影剂外渗1例;平均随访7.8个月,6例发生管腔再狭窄。结论对症状性动脉粥样硬化性颅内动脉长节段闭塞患者,血管成形术中亚满意球囊扩张后置入37mm长Enterprise支架治疗效果满意,并发症及远期管腔再狭窄发生率较低。展开更多
Purpose: To evaluate the safety and efficacy of Enterprise stent in the treatment of symptomatic complex intracranial atherosclerotic stenosis. Methods and materials: 20 complex cases among 53 patients with symptomati...Purpose: To evaluate the safety and efficacy of Enterprise stent in the treatment of symptomatic complex intracranial atherosclerotic stenosis. Methods and materials: 20 complex cases among 53 patients with symptomatic ischemic stroke who were treated with balloon angioplasty and enterprise stents in Department of Neuro-interventional Radiology, The First Affiliated Hospital of Zhengzhou University from Jan. 2014 to Dec. 2017 were retrospectively enrolled in this study. Diagnostic criteria for complex intracranial atherosclerotic stenosis were as follows: 1) intracranial atherosclerotic stenosis was ≥70% confirmed by digital subtraction angiography(DSA) using the formulas described by the Warfarin Aspirin Symptomatic Intracranial Disease(WASID) method; 2) length of lesion was >10 mm. Basic characteristics of target lesions, technical success rate, perioperative safety, follow-up outcomes were investigated. Results: 20 patients were enrolled in this study, including 15 males and 5 females from 44 to 70 years old with an average age of 57.20 ± 9.25. 20 lesions were treated with 20 enterprise stents. The average preoperative and postoperative residual stenosis was reduced from(77.45 ± 8.44)% to(24.89 ± 16.61)%. The successful rate of operation was 100%. Among the perioperative complications, only 1 case(5%) experienced perforating branch event. The average clinical follow-up period was 13.15 ± 11.33 months(time range: 5–38). There were no ischemic events, no bleeding events and no various causes of death during the follow-up period. 8 lesions(40.0%) underwent DSA follow-up examinations and 12 lesions(60.0%) were checked by CT angiography during the follow-up period. 3 lesions(15.0%) developed ISR without any cerebral ischemia symptoms. Conclusion: This retrospective, single-center study suggests that enterprise stent is effective in the treatment of symptomatic complex intracranial atherosclerotic stenosis with less perioperative complications. Prospective, multicenter, randomized controlled trials are expec展开更多
文摘目的探讨症状性动脉粥样硬化性颅内动脉长节段闭塞患者血管成形术中置入37mm长Enterprise支架治疗的效果和安全性。方法 27例症状性颅内动脉粥样硬化性长节段闭塞患者,术中亚满意球囊扩张后采用37 mm长Enterprise支架行血管成形术。记录手术情况,术后30d行改良Rankin量表(modified Rankin scale,mRS)评分评定治疗效果;比较术前1d及术后3、30d美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)评分;观察术后30d神经系统并发症发生情况;随访3～12个月,行数字减影血管造影或CT血管造影,观察管腔再狭窄发生情况。结果 3例微导丝未通过闭塞段,24例成功置入支架、血管再通,置入支架后管腔残余狭窄率为(19.2±6.9)%;术后30d治疗效果为优10例,良9例,差5例;术后3、30dNIHSS评分[(8.2±2.0)、(6.1±1.9)分]均较术前[(10.6±2.2)分]降低(P<0.05);术后30d内发生缺血性脑卒中1例,造影剂外渗1例;平均随访7.8个月,6例发生管腔再狭窄。结论对症状性动脉粥样硬化性颅内动脉长节段闭塞患者,血管成形术中亚满意球囊扩张后置入37mm长Enterprise支架治疗效果满意,并发症及远期管腔再狭窄发生率较低。
文摘Purpose: To evaluate the safety and efficacy of Enterprise stent in the treatment of symptomatic complex intracranial atherosclerotic stenosis. Methods and materials: 20 complex cases among 53 patients with symptomatic ischemic stroke who were treated with balloon angioplasty and enterprise stents in Department of Neuro-interventional Radiology, The First Affiliated Hospital of Zhengzhou University from Jan. 2014 to Dec. 2017 were retrospectively enrolled in this study. Diagnostic criteria for complex intracranial atherosclerotic stenosis were as follows: 1) intracranial atherosclerotic stenosis was ≥70% confirmed by digital subtraction angiography(DSA) using the formulas described by the Warfarin Aspirin Symptomatic Intracranial Disease(WASID) method; 2) length of lesion was >10 mm. Basic characteristics of target lesions, technical success rate, perioperative safety, follow-up outcomes were investigated. Results: 20 patients were enrolled in this study, including 15 males and 5 females from 44 to 70 years old with an average age of 57.20 ± 9.25. 20 lesions were treated with 20 enterprise stents. The average preoperative and postoperative residual stenosis was reduced from(77.45 ± 8.44)% to(24.89 ± 16.61)%. The successful rate of operation was 100%. Among the perioperative complications, only 1 case(5%) experienced perforating branch event. The average clinical follow-up period was 13.15 ± 11.33 months(time range: 5–38). There were no ischemic events, no bleeding events and no various causes of death during the follow-up period. 8 lesions(40.0%) underwent DSA follow-up examinations and 12 lesions(60.0%) were checked by CT angiography during the follow-up period. 3 lesions(15.0%) developed ISR without any cerebral ischemia symptoms. Conclusion: This retrospective, single-center study suggests that enterprise stent is effective in the treatment of symptomatic complex intracranial atherosclerotic stenosis with less perioperative complications. Prospective, multicenter, randomized controlled trials are expec
