In this paper, the design of signal constellations parameters is studied for Differential Unitary Space-Time Modulation (DUSTM) based on the design criterion of maximizing the diversity product. Further, noninteger se...In this paper, the design of signal constellations parameters is studied for Differential Unitary Space-Time Modulation (DUSTM) based on the design criterion of maximizing the diversity product. Further, noninteger searching method for the signal constellation parameters design is proposed in order to get better codes. Experimental results show that under the different Doppler spread and data transmission rate, the proposed design performs better than the previous design using integer parameters in Multiple Input Multiple Output Orthogonal Frequency Division Multiplexing (MIMO-OFDM) system over frequency-selective fading channels.展开更多
Polo-like kinase 1 （Plkl）, a member of a family of serine/threonine kinases, is an attractive target for the development of anti- cancer drugs because it is involved in the regulation of cell-cycle progression and c...Polo-like kinase 1 （Plkl）, a member of a family of serine/threonine kinases, is an attractive target for the development of anti- cancer drugs because it is involved in the regulation of cell-cycle progression and cytokinesis. This kinase provides two pock- ets for developing Plkl inhibitors： the N-terminal catalytic domain （NCD） and the polo-box domain （PBD）. For both of the two pockets, some natural products were identified as Plkl inhibitors and some synthetic Plkl inhibitors were developed by mimicking ATP and phosphopeptides, natural products binding to NCD and PBD respectively. This article not only reviews the progression of Plkl inhibitors binding to these two pockets, but also discusses diversity evolution and jump in the process of drug development using Plkl inhibitors as examples and how they impact on drug design and pharmacopbore modeling.展开更多
A new non-orthogonal space-time-frequency code (STFC) was proposed. In conjunction with orthogonal frequency-division multiplexing (OFDM), it is appropriate for the application on frequency-selective fading channels. ...A new non-orthogonal space-time-frequency code (STFC) was proposed. In conjunction with orthogonal frequency-division multiplexing (OFDM), it is appropriate for the application on frequency-selective fading channels. On the basis of the existing non-orthogonal STC, frequency diversity is studied and a new non-orthogonal STFC is further designed. Monte-Carlo simulations show that the non-orthogonal STFC-OFDM has the advantage of large diversity order, high bandwidth efficiency and better BER performance when compared with the orthogonal STC/STFC-OFDM and non-orthogonal STC-OFDM systems.展开更多
A new constellation which is the multiplication of the rotation matrix and the diagonal matrix ac- cording to the number of transmitters is proposed to increase the diversity product, the key property to the performan...A new constellation which is the multiplication of the rotation matrix and the diagonal matrix ac- cording to the number of transmitters is proposed to increase the diversity product, the key property to the performance of the differential unitary space-time modulation. Analyses and the simulation results show that the proposed constellation performs better and 2dB or more coding gain can be achieved over the traditional cyclic constellation.展开更多
基金Supported by the National High-tech R&D Program of China(No.2001AA644010,2003AA644020)the National Sci-tech Supporting Program of China(2006BAJ04A06)+1 种基金the Key Project of Chinese Ministryof Education(107122)the Shanghai-Rhone Alpes Region Interna-tional Scientific Research Cooperation Fund(06SR07105)
基金Supported by the National Natural Science Foundation of China (No.60772062)the National Basic Research Pro-gram of China (No.2007CB310607)the Natural Science Research Fund of Jiangsu University (No. 05 KJB 510090)
文摘In this paper, the design of signal constellations parameters is studied for Differential Unitary Space-Time Modulation (DUSTM) based on the design criterion of maximizing the diversity product. Further, noninteger searching method for the signal constellation parameters design is proposed in order to get better codes. Experimental results show that under the different Doppler spread and data transmission rate, the proposed design performs better than the previous design using integer parameters in Multiple Input Multiple Output Orthogonal Frequency Division Multiplexing (MIMO-OFDM) system over frequency-selective fading channels.
基金supported by the Fundamental Research Funds for the Central Universities(2013HGCH0015)
文摘Polo-like kinase 1 （Plkl）, a member of a family of serine/threonine kinases, is an attractive target for the development of anti- cancer drugs because it is involved in the regulation of cell-cycle progression and cytokinesis. This kinase provides two pock- ets for developing Plkl inhibitors： the N-terminal catalytic domain （NCD） and the polo-box domain （PBD）. For both of the two pockets, some natural products were identified as Plkl inhibitors and some synthetic Plkl inhibitors were developed by mimicking ATP and phosphopeptides, natural products binding to NCD and PBD respectively. This article not only reviews the progression of Plkl inhibitors binding to these two pockets, but also discusses diversity evolution and jump in the process of drug development using Plkl inhibitors as examples and how they impact on drug design and pharmacopbore modeling.
基金National Natural Science Foundation ofChina(No.60 3 72 0 76)
文摘A new non-orthogonal space-time-frequency code (STFC) was proposed. In conjunction with orthogonal frequency-division multiplexing (OFDM), it is appropriate for the application on frequency-selective fading channels. On the basis of the existing non-orthogonal STC, frequency diversity is studied and a new non-orthogonal STFC is further designed. Monte-Carlo simulations show that the non-orthogonal STFC-OFDM has the advantage of large diversity order, high bandwidth efficiency and better BER performance when compared with the orthogonal STC/STFC-OFDM and non-orthogonal STC-OFDM systems.
基金Supported by the National Natural Science Foundation of China (No.60402014), and the Doctoral Program Fund of China (No.20010561007).
文摘A new constellation which is the multiplication of the rotation matrix and the diagonal matrix ac- cording to the number of transmitters is proposed to increase the diversity product, the key property to the performance of the differential unitary space-time modulation. Analyses and the simulation results show that the proposed constellation performs better and 2dB or more coding gain can be achieved over the traditional cyclic constellation.
