皮肤癌是一种广泛的、可能致命的疾病。针对皮肤病病灶与背景对比度低、面积和形状变化大等特点,本文提出一种新的皮肤病病灶分割模型(SECU-Net),该模型结合“挤压和激励”机制(Squeeze and Excitation,SE)并引入条件随机场(Conditional...皮肤癌是一种广泛的、可能致命的疾病。针对皮肤病病灶与背景对比度低、面积和形状变化大等特点,本文提出一种新的皮肤病病灶分割模型(SECU-Net),该模型结合“挤压和激励”机制(Squeeze and Excitation,SE)并引入条件随机场(Conditional Random Fields,CRF)做分割后处理,是一种将概率图形模型纳入神经网络的深度学习分割框架。SECU-Net通过SE模块建模通道之间的相互依赖性,自适应地重新校准通道特性响应。同时,CRF作为U-Net网络中端到端的可训练层,通过对相邻像素进行建模,使得相同属性的像素最大概率分配到相同的标签,产生与图像视觉特征一致的结构化输出。本文通过在具有挑战的ISIC2017皮肤病数据集上进行测试,实验结果表明,SECU-Net与其它医学图像分割模型相比,有更好的效果。展开更多
As a multi-factorial degenerative disease, Parkinson＇s disease （PD） leads to tremor, gait rigidity, and hypokinesia, thus hampering normal living. As this disease is usually detected in the later stages when neuron...As a multi-factorial degenerative disease, Parkinson＇s disease （PD） leads to tremor, gait rigidity, and hypokinesia, thus hampering normal living. As this disease is usually detected in the later stages when neurons have degenerated completely, cure is on hold, ultimately leading to death due to the lack of early diagnostic techniques. Thus, biomarkers are required to detect the disease in the early stages when prevention is possible. Various biomarkers providing early diagnosis of the disease include those of imaging, cerebrospinal fluid, oxidative stress, neuroprotection, and inflammation. Also, biomarkers, alone or in combination, are used in the diagnosis and evolution of PD. This review encompasses various biomarkers available for PD and discusses recent advances in their development.展开更多
文摘皮肤癌是一种广泛的、可能致命的疾病。针对皮肤病病灶与背景对比度低、面积和形状变化大等特点,本文提出一种新的皮肤病病灶分割模型(SECU-Net),该模型结合“挤压和激励”机制(Squeeze and Excitation,SE)并引入条件随机场(Conditional Random Fields,CRF)做分割后处理,是一种将概率图形模型纳入神经网络的深度学习分割框架。SECU-Net通过SE模块建模通道之间的相互依赖性,自适应地重新校准通道特性响应。同时,CRF作为U-Net网络中端到端的可训练层,通过对相邻像素进行建模,使得相同属性的像素最大概率分配到相同的标签,产生与图像视觉特征一致的结构化输出。本文通过在具有挑战的ISIC2017皮肤病数据集上进行测试,实验结果表明,SECU-Net与其它医学图像分割模型相比,有更好的效果。
文摘As a multi-factorial degenerative disease, Parkinson＇s disease （PD） leads to tremor, gait rigidity, and hypokinesia, thus hampering normal living. As this disease is usually detected in the later stages when neurons have degenerated completely, cure is on hold, ultimately leading to death due to the lack of early diagnostic techniques. Thus, biomarkers are required to detect the disease in the early stages when prevention is possible. Various biomarkers providing early diagnosis of the disease include those of imaging, cerebrospinal fluid, oxidative stress, neuroprotection, and inflammation. Also, biomarkers, alone or in combination, are used in the diagnosis and evolution of PD. This review encompasses various biomarkers available for PD and discusses recent advances in their development.
