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DOG1 is useful for diagnosis of KIT-negative gastrointestinal stromal tumor of stomach 被引量:11
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作者 Takuya Wada Satoshi Tanabe +8 位作者 Kenji Ishido Katsuhiko Higuchi Tohru Sasaki Chikatoshi Katada Mizutomo Azuma Akira Naruke Myunguchul Kim Wasaburo Koizumi Tetsuo Mikami 《World Journal of Gastroenterology》 SCIE CAS 2013年第47期9133-9136,共4页
Approximately 80%-95%of gastrointestinal stromal tumors(GISTs)show positive staining for KIT,while the other 5%-20%show negative staining.If the tumor is negative for KIT,but is positive for CD34,a histological diagno... Approximately 80%-95%of gastrointestinal stromal tumors(GISTs)show positive staining for KIT,while the other 5%-20%show negative staining.If the tumor is negative for KIT,but is positive for CD34,a histological diagnosis is possible.However,if the tumor is negative for KIT,CD34,S-100,and SMA,a definitive diagnosis is often challenging.Recently,Discovered on GIST-1(DOG1)has received considerable attention as a useful molecule for the diagnosis of GIST.DOG1,a membrane channel protein,is known to be overexpressed in GIST.Because the sensitivity and specificity of DOG1 are higher than those of KIT,positive staining for DOG1has been reported,even in KIT-negative GISTs.KITnegative GISTs most commonly arise in the stomach and are mainly characterized by epithelioid features histologically.We describe our experience with a rare case of a KIT-negative GIST of the stomach that was diagnosed by positive immunohistochemical staining for DOG1 in a patient who presented with severe anemia.Our findings suggest that immunohistochemical staining for DOG1,in addition to gene analysis,is useful for the diagnosis of KIT-negative tumors that are suspected to be GISTs. 展开更多
关键词 KIT NEGATIVE GASTROINTESTINAL STROMAL tumors discovered on GASTROINTESTINAL STROMAL tumor-1 PLATELET-DERIVED growth factor receptor alpha
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A Newly Discovered Oil-bearing Mesoproterozoic Erathem within the Niu D1 Well, Liaoxi Depression, Yanliao Faulted Depression Zone, NE China 被引量:3
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作者 SUN Qiushi GAO Xiaoyong +5 位作者 ZONG Wenming SUN Shouliang ZHANG Tao XIAO Fei LI Yongfei SHI Lei 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2020年第1期202-203,共2页
Objective The Yanshan Fold Belt is located within the northern margin of the North China platform and contains welldeveloped and widespread Neoproterozoic and Mesoproterozoic sedimentary units with a total thickness o... Objective The Yanshan Fold Belt is located within the northern margin of the North China platform and contains welldeveloped and widespread Neoproterozoic and Mesoproterozoic sedimentary units with a total thickness of up to 9000 m.Previous studies identified many oil seedlings as well as asphalt and ancient hydrocarbon reservoirs in Northern Hebei depression and western Liaoning depression.This research indicates that the Mesoproterozoic and Neoproterozoic sedimentary units are ideally suited for the formation of significant oil and gas resources.The Niu D1 well was drilled by the China Geological Survey(CGS)in the Niuyingzi area and intercepted oil immersions and oil-and gas-bearing units within a limestone reservoir in the middle Proterozoic Gaoyuzhuang Formation(Fig.1).This study presents new biomarker compound and carbon isotope data that indicate that the oil within this formation was derived from hydrocarbon source rocks of the Hongshuizhuang Formation,part of the Mesoproterozoic Jixian Series,and the reservoir type is overthrust fault fractured anticline hydrocarbon reservoir.The oil reservoir within the Gaoyuzhuang Formation limestone might represent the oldest oil reservoir discovered to date within the Yanliao faulted depression zone. 展开更多
关键词 NE China A NEWLY discovered Oil-bearing MESOPROTEROZOIC Erathem within the Niu D1 WELL Yanliao Faulted DEPRESSION ZONE Liaoxi DEPRESSION
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广西马山县HIV/AIDS发现即治疗预防措施结果分析 被引量:3
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作者 黄海洪 曾世培 +4 位作者 覃宁 黄群 黄舒婷 甘艳 曾翠柳 《医学动物防制》 2017年第3期312-314,共3页
目的探讨马山县HIV/AIDS发现即治疗预防措施及传染源管理模式,为今后艾滋病防治措施的制定提供参考。方法对2014年马山县发现的HIV/AIDS转介治疗。采用Excel 2003对资料进行统计,应用描述性流行病学方法进行分析。结果 2014年发现病例... 目的探讨马山县HIV/AIDS发现即治疗预防措施及传染源管理模式,为今后艾滋病防治措施的制定提供参考。方法对2014年马山县发现的HIV/AIDS转介治疗。采用Excel 2003对资料进行统计,应用描述性流行病学方法进行分析。结果 2014年发现病例的治疗率为77.36%,存活病例治疗率为81.63%,死亡病例治疗率为25.00%,两者差异有统计学意义(χ2=10.50,P<0.01)。参加抗病毒治疗的单阳家庭阴性配偶未发现阳转情况。结论 HIV/AIDS发现即治疗可延长病例寿命,减少HIV传播,有效管理传染源。 展开更多
关键词 艾滋病 发现 治疗 预防措施
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Two Super-Large Gold Deposits Have Been Discovered in Jiaodong Peninsula of China 被引量:3
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作者 HAO Ziguo FEI Hongcai +1 位作者 HAO Qingqing LIU Lian 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2016年第1期368-369,共2页
During 2015, gold prospecting in Laizhou City of Shandong Peninsula in China has achieved a major breakthrough. Deposits containing 470 and 389 tons of gold metal were discovered in the northern sea area of Sanshandao... During 2015, gold prospecting in Laizhou City of Shandong Peninsula in China has achieved a major breakthrough. Deposits containing 470 and 389 tons of gold metal were discovered in the northern sea area of Sanshandao and the Shaling area, respectively. As a result, the gold prospective resources in the entire Jiaodong Peninsula have now exceeded 4000 tons, fully indicative of the super-large prospecting potential of the Jiaojia-type deposits. 展开更多
关键词 GOLD Two Super-Large Gold Deposits Have Been discovered in Jiaodong Peninsula of China
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Significant New Dinosaur Egg Fossils Discovered in 2017 被引量:1
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作者 HAO Ziguo FEI Hongcai +1 位作者 HAO Qingqing LIU Lian 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2017年第6期2302-2304,共3页
1 Dinosaur Eggs in Yiwu City, Zhejiang Province In February 2017, dinosaur egg fossils were discovered in China Town part of Yiwu City, Zhejiang Province. They were confirmed by dinosaur experts from the Zhejiang Muse... 1 Dinosaur Eggs in Yiwu City, Zhejiang Province In February 2017, dinosaur egg fossils were discovered in China Town part of Yiwu City, Zhejiang Province. They were confirmed by dinosaur experts from the Zhejiang Museum of Natural History to be those of Mesozoic herbivorous dinosaurs (Fig. 1). Not long before, Yiwu Museum staff had discovered dinosaur eggs close by this place. 展开更多
关键词 Significant New Dinosaur Egg Fossils discovered 2017
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China First Discovered Massive Available Hot Dry Rock Resources 被引量:2
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作者 HAO Ziguo FEI Hongcai +1 位作者 HAO Qingqing LIU Lian 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2015年第3期1039-1040,共2页
Hot Dry Rock (HDR) refers to those generally deeply buried impermeable metamorphic or crystallized biotite gneiss, granite and granodiorite rock bodies, with a burial depth greater than 2000 m, containing no water o... Hot Dry Rock (HDR) refers to those generally deeply buried impermeable metamorphic or crystallized biotite gneiss, granite and granodiorite rock bodies, with a burial depth greater than 2000 m, containing no water or vapor. HDR is as implied, hot and dry, with temperatures ranging from 150 to 650℃, and it can be utilized as a heat resource. Because this type of heat system does not require porosity, permeability and fluids and is widespread at the drillable depth range of 10 kin, it is thereby an infinite resource type. By contrast, thermal power generation results in copious pollution; wind power is irregular and unstable; solar energy occupies large areas. 展开更多
关键词 HDR China First discovered Massive Available Hot Dry Rock Resources ROCK
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A Large Dinosaur Assemblage has been Discovered in Pu'an,Yunyang County,Chongqing,China 被引量:2
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作者 HAO Ziguo FEI Hongcai +1 位作者 HAO Qingqing LIU Lian 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2017年第4期1487-1488,共2页
In June 2017, the Chongqing Municipal Govemment and Chinese scientists announced the discovery of a world -class dinosaur assemblage in Pu'an, a town of Yunyang County, Chongqing. This group of skeletons was buried i... In June 2017, the Chongqing Municipal Govemment and Chinese scientists announced the discovery of a world -class dinosaur assemblage in Pu'an, a town of Yunyang County, Chongqing. This group of skeletons was buried in the Jurassic Ziliujing Formation Da'anzhai member and the lower and upper members of the Shaximiao Formation. 展开更多
关键词 In A Large Dinosaur Assemblage has been discovered in Pu’an Yunyang County Chongqing China
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Newly Discovered Fluvial-Lacustrine Sediments in the Western Yangtze Block and their Geological Significance for the Emeishan Large Igneous Province 被引量:2
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作者 MABI Awei ZHANG Mingchun +3 位作者 YANG Zhengxi LI Yanlong WEN Dengkui LIU Xuyang 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2017年第2期741-742,共2页
Objective The Emeishan large igneous province (ELIP) in SW China is the only one large igneous province in China recognized by international geologists. Previous studies of ELIP over past two decades indicate that ... Objective The Emeishan large igneous province (ELIP) in SW China is the only one large igneous province in China recognized by international geologists. Previous studies of ELIP over past two decades indicate that the ELIP age, duration, scale and generation mechanism are still controversial. Among those scientific topics, some scholars suggest that ELIP is an example of up-doming prior to LIP formation, which was evidenced by: (1) The thickness of the Yangxin Formation (P^v) limestone unit, which lies directly beneath ELIP, reduces from the center of erosional area to the outer edge. (2) Paleo-karst surfaces are present. (3) The clastic rocks of alluvial fan deposits, from the eroded materials in the maximum uplifted area, developed surrounding the inner zone. However, other scholars urge that those so-called "alluvial fan" deposits are "hydromagmatic deposits", erupted or emplaced at or near sea level, and conclude that there was no pre-emptive uplift in ELIP. In order to constrain the above-mentioned scientific issue, we conducted detailed field geological investigations and systematically measured geological sections to provide new evidence by using sedimentary data. 展开更多
关键词 Newly discovered Fluvial-Lacustrine Sediments in the Western Yangtze Block and their Geological Significance for the Emeishan Large Igneous Province
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Seismic Signature Analysis for Clarification of Mud Volcanoes from the New Mud Diapirs Discovered at the NE-SW Moroccan Atlantic Margin
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作者 Asher Hategekamungu Nadia Mhammdi Amine Manar Mohamed 《Open Journal of Geology》 CAS 2022年第11期973-982,共10页
Our aim is to clarify mud volcanoes from the new mud diapirs resulting from the seismic attributes analysis applied to the low resolution Burmah oil “1973-1974” seismic data. The latter was carried out on the Larach... Our aim is to clarify mud volcanoes from the new mud diapirs resulting from the seismic attributes analysis applied to the low resolution Burmah oil “1973-1974” seismic data. The latter was carried out on the Larache and Tanger-Larache offshores from the NE-SW Atlantic margin. The high resolution seismic data was essential for this evaluation. In this case, we applied seismic signature analysis to four seismic profiles from the map of the seismic data set, which includes all new mud diapirs. This helped us to classify different types of mud diapirs within the seismic profiles. And as a result, six deep mud diapirs from the Prerifaine Nappe of Morocco, a shallow mud diapir, and four seafloor-piercing mud diapirs have been observed. Furthermore, the seafloor-piercing mud diapirs show a mushroom-shaped and conical-shaped cone. As they break through the seafloor, these kinds of cones characterize mud volcanoes. In this case, we may conclude that the resultant seafloor-piercing mud diapirs are likely to be mud volcanoes. However, more geological sampling and seafloor observation are still required. 展开更多
关键词 Seismic Signature Analysis CLARIFICATION Mud Volcanoes discovered Mud Diapirs NW-SW Moroccan Margin
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A set of source-and age-diagnostic biomarkers discovered in the marine oils 被引量:1
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作者 WANG Guangli ZHANG Qin +2 位作者 YANG Xiaofa MA Zhongzhen XIE Yinfu 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2017年第S1期285-286,共2页
1 Introduction Biological markers or biomarkers(Eglinton et al.,1964;Eglinton and Calvin,1967)are molecular fossils,which were derived from once living organisms through the earth history.They occur in sediments,rocks... 1 Introduction Biological markers or biomarkers(Eglinton et al.,1964;Eglinton and Calvin,1967)are molecular fossils,which were derived from once living organisms through the earth history.They occur in sediments,rocks,and crude 展开更多
关键词 In WANG A set of source-and age-diagnostic biomarkers discovered in the marine oils GC
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牛顿与万有引力定律的发现 被引量:1
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作者 朱小村 《湖南科技学院学报》 2006年第5期67-69,共3页
牛顿发现万有引力定律有一个复杂、长期的演变过程。而不是那种广为流传的牛顿看到“苹果落地”就发现了万有引力定律。把牛顿的创作过程呈现给学生,让他们体验到科学发展过程的艰辛,从而形成正确的科学态度和科学精神。
关键词 万有引力定律 发现 牛顿 创作
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A Megaton Tungsten Deposit Discovered in Dahutang, Jiangxi Province 被引量:1
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作者 Hao Ziguo, Fei Hongcai and Liu Lian 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2012年第5期1312-1313,共2页
Jiangxi Province, China's largest base tbr tungsten production and export is known as the world capital of tungsten. By the end of 2002, there were 72 primary tungsten deposits tbund, with accumulated reserves and a ... Jiangxi Province, China's largest base tbr tungsten production and export is known as the world capital of tungsten. By the end of 2002, there were 72 primary tungsten deposits tbund, with accumulated reserves and a proven resource of reserves of 1.9 Mt and 1.12 Mt, respectively, accounting for 20 percent of China's total reserves. 展开更多
关键词 Jiangxi Province A Megaton Tungsten Deposit discovered in Dahutang
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China's Largest Granite-Type Gas Field was Discovered in Qinghai——The Inorganic Theory has Aroused Attention again 被引量:1
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作者 HAO Ziguo FEI Hongcai +1 位作者 LIU Lian HAO Qingqing 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2015年第1期302-303,共2页
A growing number of oil and gas reservoirs have been discovered in granite and metamorphic crystallized rock areas. Statistics show that, about 157 oil and gas fields were found in crystallized bedrocks, with oil rese... A growing number of oil and gas reservoirs have been discovered in granite and metamorphic crystallized rock areas. Statistics show that, about 157 oil and gas fields were found in crystallized bedrocks, with oil reserves of 5048x 10^8 t, and gas reserves of 2681x10^8m3. Among the discovered industrial oil and gas fields hosted in crystallized rocks, most occurred in granite rocks, occupying 40% in quantity and 75% in reserves, followed by those hosted in mafic and ultra-mafic rocks (about 3%), and then tbllowed by those in volcanic rocks and metamorphic rocks. 展开更多
关键词 The Inorganic Theory has Aroused Attention again China’s Largest Granite-Type Gas Field was discovered in Qinghai
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A New Dinosaur Fauna is Discovered in Yunyang, Chongqing, China 被引量:1
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作者 DAI Hui MA Qingyu +3 位作者 HU Xufeng ZHOU Yuxuan TAN Chao LI Ning 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2020年第1期216-217,共2页
The 2019 Annual Symposium on Yunyang Dinosaur Fossil Protection and Research was held in Chongqing on December 16,2019.It was proposed in the symposium that the dinosaurs discovered from the early Middle Jurassic Xint... The 2019 Annual Symposium on Yunyang Dinosaur Fossil Protection and Research was held in Chongqing on December 16,2019.It was proposed in the symposium that the dinosaurs discovered from the early Middle Jurassic Xintiangou Formation in Yunyang,Chongqing could represent a new dinosaur fauna.Previously,only a few dinosaurs have been reported from the Xintiangou Formation.Moreover,the Xintiangou dinosaurs are playing an important role in studying the evolutionary sequence of dinosaurs,and have the potential to fill the gaps during the Early-Middle dinosaur turnover. 展开更多
关键词 A NEW DINOSAUR FAUNA IS discovered in Yunyang CHONGQING
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The Firstly Discovered Cosmic Spherules in Carbonaceous Siltstone from the Taizi Formation of the Mesoproterozoic Shennongjia Group,Central China 被引量:1
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作者 KUANG Hongwei SONG Tianrui +7 位作者 LIU Yongqing PENG Nan ZHU Zhicai FAN Zhengxiu WANG Yuchong XIA Xiaoxu SONG Huanxin TANG Yong 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2017年第3期1137-1138,共2页
Objective Spherical micro-particles are often preserved in Precambrian sedimentary rocks. Finnish and Chinese scholars have previously discovered carbonaceous, siliceous or ferruginous spherules of out-space origin in... Objective Spherical micro-particles are often preserved in Precambrian sedimentary rocks. Finnish and Chinese scholars have previously discovered carbonaceous, siliceous or ferruginous spherules of out-space origin in the 1.6 Ga and 1.4 Ga sequence, respectively. The presence of spherules can record possible cosmic impact events. Also, cosmic spherules provide important information on the evolution of planets from outer space. 展开更多
关键词 of on or is from The Firstly discovered Cosmic Spherules in Carbonaceous Siltstone from the Taizi Formation of the Mesoproterozoic Shennongjia Group Central China in
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Newly Discovered Ca. 163 Ma OIB-Type Diabase Dike from the Shiquanhe Ophiolites, Western Tibet
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作者 LI Chenwei LI Zhijun +1 位作者 CAO Hui ZENG Min 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2018年第6期2443-2444,共2页
Objective The Shiquanhe ophiolite is an important tectonic belt in western Tibet. It has been debated whether the Shiquanhe ophiolite represents an allochthonous nappe derived from the Bangong-Nujiang suture zone to t... Objective The Shiquanhe ophiolite is an important tectonic belt in western Tibet. It has been debated whether the Shiquanhe ophiolite represents an allochthonous nappe derived from the Bangong-Nujiang suture zone to the north or the 展开更多
关键词 OIB Th Pb Ma OIB-Type Diabase Dike from the Shiquanhe Ophiolites Newly discovered Ca
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Many New Dinosaur Fossil Spots Discovered in the Dunhuang-Yumenguan-Jiuquan Area of Gansu Province, China
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作者 HAO Ziguo FEI Hongcai +1 位作者 HAO Qingqing LIU Lian 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2017年第5期1904-1905,共2页
Two Mesozoic intramontane basins are developed in the Dunhuang-Yumenguan-Jiuquan area of Gansu Province,China,i.e.,the Gongpoquan Basin(E97°30′-98°10′,N41°30′-41°45′)and the Yujingzi Basin(E... Two Mesozoic intramontane basins are developed in the Dunhuang-Yumenguan-Jiuquan area of Gansu Province,China,i.e.,the Gongpoquan Basin(E97°30′-98°10′,N41°30′-41°45′)and the Yujingzi Basin(E98°15′-99°00′,N40°15'-40°40')(Fig.1).A large number of dinosaurs and other fossils have been discovered in these two basins,which are called dinosaur'tribes'by paleontologists. 展开更多
关键词 China Many New Dinosaur Fossil Spots discovered in the Dunhuang-Yumenguan-Jiuquan Area of Gansu Province
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105 Tons of Gold Resource Amounts Have Been Newly Discovered in Tongbai Mountain,Henan Province
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作者 HAO Ziguo FEI Hongcai +1 位作者 HAO Qingqing LIU Lian 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2016年第5期1903-1904,共2页
In September 2016, the Department of Land and Resources of ttenan Province announced that the First Geological Exploration Institute of Henan Bureau of Geo- Exploration & Mineral Development had recently discovered a... In September 2016, the Department of Land and Resources of ttenan Province announced that the First Geological Exploration Institute of Henan Bureau of Geo- Exploration & Mineral Development had recently discovered a new104.96-ton gold resource, with 122.034 tons of associated silver and also abundant natural soda and lead-zinc mineral resources in the deep and peripheral areas of the Laowan gold deposit in Tongbai County. 展开更多
关键词 Tons of Gold Resource Amounts Have Been Newly discovered in Tongbai Mountain Henan Province REE
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A Report of the Newly Discovered Cu–Ni Ore Deposit in the West of East Tianshan, North Xinjiang, China
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作者 CHEN Baoyun YU Jinjie +4 位作者 WANG Junliang TIAN Jiangtao LI Dahai LIU shuaijie WANG Cheng 《Acta Geologica Sinica(English Edition)》 CAS CSCD 2018年第2期857-858,共2页
Objective The Early Permian mafic-ultramafic intrusions (298- 270 Ma, Mao et al., 2008), which are widely distributed in different tectonic domains in North Xinjiang, host magmatic sulfide ore deposits, making Nort... Objective The Early Permian mafic-ultramafic intrusions (298- 270 Ma, Mao et al., 2008), which are widely distributed in different tectonic domains in North Xinjiang, host magmatic sulfide ore deposits, making North Xinjiang the second most important region for Ni resources in China. The bulk of Cu-Ni ore deposits in East Tianshan, making up a large portion of Ni resources in North Xinjiang, were concentrated in the east of East Tianshan (the Huangshan- Jing'erquan region) (Feng Yanqing, et al., 2017), while no any analogue was discovered in the west of East Tianshan until the Lubei Cu-Ni (Co) ore deposit (90°21'E, 42°10rN) was identified by Xinjiang Geological Survey in 2014. The Lubei Cu-Ni (Co) ore deposit is a medium- to large- sized deposit with Ni and Cu grades in the range 0.2%- 7.76% and 0.2%-2.30%, respectively. This work has initiated the prospection for a large-sized Cu-Ni ore deposit in the west of East Tianshan. 展开更多
关键词 North Xinjiang A Report of the Newly discovered Cu China Ni Ore Deposit in the West of East Tianshan
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New Stone Artifacts Discovered by Xardai Co Lake
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作者 Huo Wei 《China's Tibet》 1994年第6期22-23,共2页
Early on the aftermnoon of May 24,1992,1 members of the Tibet Cultural Relics Survey Team discovered 93 stone implements in a 5,000 square meter area on the northeast banks of Xardai Co Lake in Ngari.
关键词 New Stone Artifacts discovered by Xardai Co Lake CO
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