目的:探讨宫腔镜检查在子宫内膜癌患者中的诊断价值,分析其是否增加子宫内膜癌细胞的腹腔内播散及对患者临床结局的影响。方法:计算机检索Pubmed、Web of science、Elsevier、CNKI等数据库,搜集子宫内膜癌患者术前进行和未进行宫腔镜检...目的:探讨宫腔镜检查在子宫内膜癌患者中的诊断价值,分析其是否增加子宫内膜癌细胞的腹腔内播散及对患者临床结局的影响。方法:计算机检索Pubmed、Web of science、Elsevier、CNKI等数据库,搜集子宫内膜癌患者术前进行和未进行宫腔镜检查的随机对照或病例对照实验。采用Rev Man 5.3及Stata12.0软件进行Meta分析。结果:共纳入22篇文献,共7127例子宫内膜癌患者。Meta分析结果显示,子宫内膜癌患者术前行宫腔镜检查组与未行宫腔镜检查组比较,不增加患者癌细胞腹腔内播散的风险(OR=1.61,95%CI为0.94~1.43,P=0.18)。宫腔镜检查组中,腹腔冲洗液细胞学阳性率与采用的膨宫介质相关,液体膨宫介质增加腹腔冲洗液肿瘤细胞阳性率,且使用盐水时最显著(OR=1.54,95%CI为1.08~2.19,P=0.02)。对3篇文献合并分析两组的5年总存活率及无病生存率,HR分别为1.28(0.75~2.17)和1.17(0.63~2.15)。结论:子宫内膜癌患者术前行宫腔镜检查能提高诊断准确性,且不增加癌细胞的腹腔内播散,亦无证据表明宫腔镜检查可导致不良临床结局,是较理想的检测手段;盐水等液体介质是腹腔冲洗液细胞学阳性的高危因素之一,应慎用。展开更多
Allan Poe has been deemed as the founder of modern detective story. This paper mainly talks about his contributions tomake this new genre a formal sub-genre of literature. Techniques he used in his short stories, lock...Allan Poe has been deemed as the founder of modern detective story. This paper mainly talks about his contributions tomake this new genre a formal sub-genre of literature. Techniques he used in his short stories, locked-room murder and the arm-chair detective, have become the classical conventions of detective story. The eccentric but brilliant protagonist, Auguste Dupin inhis story, has become a model of the later detectives. Poe has also contributed to define the detective story as some kind of intellec-tual game, the plot of which concentrates on the process of investigation.展开更多
It is a crucial problem in gene engineering whether an exogenous gene could be correctly expressed in cells of transgenic animal or plant, and how the expression products could be detected quantitatively in translatio...It is a crucial problem in gene engineering whether an exogenous gene could be correctly expressed in cells of transgenic animal or plant, and how the expression products could be detected quantitatively in translational level. It is very difficult to analyze some gene expression products, such as isopentenyl transferase (ipt), in transgenic investigation because they are trace in organisms. A convenient method is described to determine trace content gene expression product which is hard to purify. The method includes predicting and synthesizing the antigenic peptide according to the cDNA sequence, coupling the synthetic antigenic peptide with carrier protein, raising specific antibodies against the synthetic antigen, and detecting the gene expression product by ELISA and Western blot.展开更多
The identification of contamination sources within the food chain with polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzo-furans (PCDFs), (“dioxins”), and PCBs is difficult and complex. PCDD/PCDF ...The identification of contamination sources within the food chain with polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzo-furans (PCDFs), (“dioxins”), and PCBs is difficult and complex. PCDD/PCDF can be formed as unintentional compounds in a number of chemical processes as well as in almost every combustion process. PCBs were intentionally produced chemicals that were manufactured for decades before the ban in marketing and use in many countries around 1985. The pattern of occurrence can change from the original source in particular via feedingstuffs to food of animal origin as result of bioaccumulation. A number of examples illustrate the challenging detective work and key scientific aspects for identification of the sources, for support of the risk management and for performance of monitoring programs. The contamination of milk and milk products in European countries with dioxins was caused by compound feeds containing citrus pulp pellets from Brazil which had high dioxin levels as a result of the use of heavily contaminated lime used for neutralization. The Belgian dioxin crisis was caused by a feed additive heavily contaminated with PCBs which were discharged into a recycled fat used in the production of animal feed. Guar gum from India was contaminated with sodium pentachlorophenate and dioxins. Clay was found to be possibly highly contaminated with dioxins possibly formed by geothermal processes over time;use of such clay as feed additive or for human intake led to elevated dioxin levels in food and humans. Bioanalytical screening in combination with comprehensive physicochemical investigations led to the detection of brominated flame retardants and brominated dioxins in a feed additive. Buffalo milk was contaminated in Italy presumably caused by illegal deposition of waste. High PCB levels in fuel oil for drying of breadcrumb used as a feed ingredient caused a major dioxin crisis with pork meat in Ireland. Fatty acids for technical purposes originating from a biodiesel company were u展开更多
Compared with other kinds of fiction,detective story is a kind of fiction with different characteristics,it involves a process of thinking,analysis,inference,interaction.This passage mainly discusses detective story&#...Compared with other kinds of fiction,detective story is a kind of fiction with different characteristics,it involves a process of thinking,analysis,inference,interaction.This passage mainly discusses detective story's characteristics as a kind of intellectual game and reader's psychology during reading.展开更多
The scientific study of crime comes under the general categories of forensic science and criminology, which include a large set of related branches, from forensic psychology to computer forensics. The emergence of for...The scientific study of crime comes under the general categories of forensic science and criminology, which include a large set of related branches, from forensic psychology to computer forensics. The emergence of forensic semiotics as part of this interdisciplinary amalgam is relatively unknown among both criminologists and semioticians. This paper provides an overview of the main objectives of forensic semiotics and its importance to the study of crime. One of the premises of forensic semiotics is that there is a thematic and interpretive continuity between actual crimes and their fictional representations. Actually, contemporary semiotics itself can be seen to start with Peirce's interest in detective fiction, from which he developed several of his key ideas, including the theory of abduction. This paper also discusses some case studies that have been carried out under the rubric of forensic semiotics, which indicate the relevance of semiotic analysis to the study of crime.展开更多
Modern detective novels are believed to have their roots in Sir Arthur Conan Doyle's Sherlock Holmes, when nearly fifty years prior Edgar Allen Poe had published one of the first murder mysteries in history. Altho...Modern detective novels are believed to have their roots in Sir Arthur Conan Doyle's Sherlock Holmes, when nearly fifty years prior Edgar Allen Poe had published one of the first murder mysteries in history. Although many years had elapsed little change had been made to the major elements of these detective stories. This essay explores the similarities of"Murders in the Rue Morgue"and"Hound of the Baskervilles".展开更多
As the world-famous Queen of Crime,Agatha Christie not only won great honor for detective fiction but also made a significant contribution towards helping popular novels step into the palace of elegant culture.The met...As the world-famous Queen of Crime,Agatha Christie not only won great honor for detective fiction but also made a significant contribution towards helping popular novels step into the palace of elegant culture.The methods like analysis and contrast are used in this paper to analyze its unique artistic value of her detective works from the artistic technique employed and her antiheroic qualities as a feminine detective fiction writer.展开更多
This paper,in the frame of Barthes and Foucault's ideas about the"Author",explores the complicated relationship between the author and reader by comparing the classical detective story,Edgar Allen Poe...This paper,in the frame of Barthes and Foucault's ideas about the"Author",explores the complicated relationship between the author and reader by comparing the classical detective story,Edgar Allen Poe's The Murder in the Rue Morgue,and the metaphysical detective story,Paul Auster'City of Glass and Umberto Eco's The Name of the Rose.These two stories investigate the perspectives;the story of crime and the story of investigation.展开更多
Despite of only producing five ratiocinative tales in the whole life,Edgar Allan Poe is acknowledged as the "father of the detective story".In those tales,Poe portrays the hero Dupin who is the first detecti...Despite of only producing five ratiocinative tales in the whole life,Edgar Allan Poe is acknowledged as the "father of the detective story".In those tales,Poe portrays the hero Dupin who is the first detective image in the history of the western literature vividly.Based on the stories in which Dupin appeared,concerns on the creation of Dupin,the analysis of his features and the function of the setting fellows,like friend and police,summarizing the traditional image pattern of detective stories created by Poe,revealing the great influence Poe had on the development of detective literature,even on the literature of the whole world.展开更多
Sherlock Holmes is a fictional detective created by Sir Arthur Conan Doyle, the Scottish author and physician. As a London-based "consulting detective" whose abilities border on the fantastic, Holmes is famo...Sherlock Holmes is a fictional detective created by Sir Arthur Conan Doyle, the Scottish author and physician. As a London-based "consulting detective" whose abilities border on the fantastic, Holmes is famous for his astute logical reasoning, his ability to adopt almost any disguise, and his use of forensic science skills to solve difficult cases. The paper tries to analyze the characteristics of the Holmes and how did Holmes observe evidences and analyze clues.展开更多
文摘目的:探讨宫腔镜检查在子宫内膜癌患者中的诊断价值,分析其是否增加子宫内膜癌细胞的腹腔内播散及对患者临床结局的影响。方法:计算机检索Pubmed、Web of science、Elsevier、CNKI等数据库,搜集子宫内膜癌患者术前进行和未进行宫腔镜检查的随机对照或病例对照实验。采用Rev Man 5.3及Stata12.0软件进行Meta分析。结果:共纳入22篇文献,共7127例子宫内膜癌患者。Meta分析结果显示,子宫内膜癌患者术前行宫腔镜检查组与未行宫腔镜检查组比较,不增加患者癌细胞腹腔内播散的风险(OR=1.61,95%CI为0.94~1.43,P=0.18)。宫腔镜检查组中,腹腔冲洗液细胞学阳性率与采用的膨宫介质相关,液体膨宫介质增加腹腔冲洗液肿瘤细胞阳性率,且使用盐水时最显著(OR=1.54,95%CI为1.08~2.19,P=0.02)。对3篇文献合并分析两组的5年总存活率及无病生存率,HR分别为1.28(0.75~2.17)和1.17(0.63~2.15)。结论:子宫内膜癌患者术前行宫腔镜检查能提高诊断准确性,且不增加癌细胞的腹腔内播散,亦无证据表明宫腔镜检查可导致不良临床结局,是较理想的检测手段;盐水等液体介质是腹腔冲洗液细胞学阳性的高危因素之一,应慎用。
文摘Allan Poe has been deemed as the founder of modern detective story. This paper mainly talks about his contributions tomake this new genre a formal sub-genre of literature. Techniques he used in his short stories, locked-room murder and the arm-chair detective, have become the classical conventions of detective story. The eccentric but brilliant protagonist, Auguste Dupin inhis story, has become a model of the later detectives. Poe has also contributed to define the detective story as some kind of intellec-tual game, the plot of which concentrates on the process of investigation.
文摘It is a crucial problem in gene engineering whether an exogenous gene could be correctly expressed in cells of transgenic animal or plant, and how the expression products could be detected quantitatively in translational level. It is very difficult to analyze some gene expression products, such as isopentenyl transferase (ipt), in transgenic investigation because they are trace in organisms. A convenient method is described to determine trace content gene expression product which is hard to purify. The method includes predicting and synthesizing the antigenic peptide according to the cDNA sequence, coupling the synthetic antigenic peptide with carrier protein, raising specific antibodies against the synthetic antigen, and detecting the gene expression product by ELISA and Western blot.
文摘The identification of contamination sources within the food chain with polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzo-furans (PCDFs), (“dioxins”), and PCBs is difficult and complex. PCDD/PCDF can be formed as unintentional compounds in a number of chemical processes as well as in almost every combustion process. PCBs were intentionally produced chemicals that were manufactured for decades before the ban in marketing and use in many countries around 1985. The pattern of occurrence can change from the original source in particular via feedingstuffs to food of animal origin as result of bioaccumulation. A number of examples illustrate the challenging detective work and key scientific aspects for identification of the sources, for support of the risk management and for performance of monitoring programs. The contamination of milk and milk products in European countries with dioxins was caused by compound feeds containing citrus pulp pellets from Brazil which had high dioxin levels as a result of the use of heavily contaminated lime used for neutralization. The Belgian dioxin crisis was caused by a feed additive heavily contaminated with PCBs which were discharged into a recycled fat used in the production of animal feed. Guar gum from India was contaminated with sodium pentachlorophenate and dioxins. Clay was found to be possibly highly contaminated with dioxins possibly formed by geothermal processes over time;use of such clay as feed additive or for human intake led to elevated dioxin levels in food and humans. Bioanalytical screening in combination with comprehensive physicochemical investigations led to the detection of brominated flame retardants and brominated dioxins in a feed additive. Buffalo milk was contaminated in Italy presumably caused by illegal deposition of waste. High PCB levels in fuel oil for drying of breadcrumb used as a feed ingredient caused a major dioxin crisis with pork meat in Ireland. Fatty acids for technical purposes originating from a biodiesel company were u
文摘Compared with other kinds of fiction,detective story is a kind of fiction with different characteristics,it involves a process of thinking,analysis,inference,interaction.This passage mainly discusses detective story's characteristics as a kind of intellectual game and reader's psychology during reading.
文摘The scientific study of crime comes under the general categories of forensic science and criminology, which include a large set of related branches, from forensic psychology to computer forensics. The emergence of forensic semiotics as part of this interdisciplinary amalgam is relatively unknown among both criminologists and semioticians. This paper provides an overview of the main objectives of forensic semiotics and its importance to the study of crime. One of the premises of forensic semiotics is that there is a thematic and interpretive continuity between actual crimes and their fictional representations. Actually, contemporary semiotics itself can be seen to start with Peirce's interest in detective fiction, from which he developed several of his key ideas, including the theory of abduction. This paper also discusses some case studies that have been carried out under the rubric of forensic semiotics, which indicate the relevance of semiotic analysis to the study of crime.
文摘Modern detective novels are believed to have their roots in Sir Arthur Conan Doyle's Sherlock Holmes, when nearly fifty years prior Edgar Allen Poe had published one of the first murder mysteries in history. Although many years had elapsed little change had been made to the major elements of these detective stories. This essay explores the similarities of"Murders in the Rue Morgue"and"Hound of the Baskervilles".
文摘As the world-famous Queen of Crime,Agatha Christie not only won great honor for detective fiction but also made a significant contribution towards helping popular novels step into the palace of elegant culture.The methods like analysis and contrast are used in this paper to analyze its unique artistic value of her detective works from the artistic technique employed and her antiheroic qualities as a feminine detective fiction writer.
文摘This paper,in the frame of Barthes and Foucault's ideas about the"Author",explores the complicated relationship between the author and reader by comparing the classical detective story,Edgar Allen Poe's The Murder in the Rue Morgue,and the metaphysical detective story,Paul Auster'City of Glass and Umberto Eco's The Name of the Rose.These two stories investigate the perspectives;the story of crime and the story of investigation.
文摘Despite of only producing five ratiocinative tales in the whole life,Edgar Allan Poe is acknowledged as the "father of the detective story".In those tales,Poe portrays the hero Dupin who is the first detective image in the history of the western literature vividly.Based on the stories in which Dupin appeared,concerns on the creation of Dupin,the analysis of his features and the function of the setting fellows,like friend and police,summarizing the traditional image pattern of detective stories created by Poe,revealing the great influence Poe had on the development of detective literature,even on the literature of the whole world.
文摘Sherlock Holmes is a fictional detective created by Sir Arthur Conan Doyle, the Scottish author and physician. As a London-based "consulting detective" whose abilities border on the fantastic, Holmes is famous for his astute logical reasoning, his ability to adopt almost any disguise, and his use of forensic science skills to solve difficult cases. The paper tries to analyze the characteristics of the Holmes and how did Holmes observe evidences and analyze clues.
