This paper transforms fuzzy number into clear number using the centroid method, thus we can research the traditional linear regression model which is transformed from the fuzzy linear regression model. The model’s in...This paper transforms fuzzy number into clear number using the centroid method, thus we can research the traditional linear regression model which is transformed from the fuzzy linear regression model. The model’s input and output are fuzzy numbers, and the regression coefficients are clear numbers. This paper considers the parameter estimation and impact analysis based on data deletion. Through the study of example and comparison with other models, it can be concluded that the model in this paper is applied easily and better.展开更多
Dear Editor,I am Dr.Jia X from the Department of Ophthalmology,Second Xiangya Hospital,Central South University,Changsha,China.I write to present a rare case report of 9p deletion syndrome with congenital infantile gl...Dear Editor,I am Dr.Jia X from the Department of Ophthalmology,Second Xiangya Hospital,Central South University,Changsha,China.I write to present a rare case report of 9p deletion syndrome with congenital infantile glaucoma in an infant,accompanying with an effective method of both diagnosis and treatment.展开更多
目的建立一种基于两对交叉引物PCR技术(PCR with confronting two-pair primers,PCR-CTPP)同时快速检测非缺失型α地中海贫血WS、QS和CS三种突变类型的方法及其在临床中的应用。方法根据α珠蛋白基因中发生WS、QS和CS突变的区域基因序列...目的建立一种基于两对交叉引物PCR技术(PCR with confronting two-pair primers,PCR-CTPP)同时快速检测非缺失型α地中海贫血WS、QS和CS三种突变类型的方法及其在临床中的应用。方法根据α珠蛋白基因中发生WS、QS和CS突变的区域基因序列,分别针对单个位点设计两对引物即通用外引物和特异性引物,经过聚合酶链反应、电泳鉴别基因型,同时检测非缺失型α地中海贫血。将该方法与PCR反向斑点杂交(PCR-RDB)技术比较,验证其检测准确性。结果PCR-CTPP方法可用于准确检测非缺失型α地中海贫血的WS、QS和CS突变类型,结果显示与常规非缺失型α地中海贫血PCR-RDB检测方法一致。结论PCR-CTPP技术检测非缺失型α地中海贫血WS、QS、CS三种突变位点,简单快速、经济省力,可用于非缺失型α地中海贫血的快速筛查和分子流行病学研究,适合在一般实验室推广应用。适用于非缺失型α地中海贫血的人群筛查及婚前或产前筛查,适合各个层次医院应用。展开更多
文摘This paper transforms fuzzy number into clear number using the centroid method, thus we can research the traditional linear regression model which is transformed from the fuzzy linear regression model. The model’s input and output are fuzzy numbers, and the regression coefficients are clear numbers. This paper considers the parameter estimation and impact analysis based on data deletion. Through the study of example and comparison with other models, it can be concluded that the model in this paper is applied easily and better.
基金Supported by the Natural Science Foundation of China(No.81370913)
文摘Dear Editor,I am Dr.Jia X from the Department of Ophthalmology,Second Xiangya Hospital,Central South University,Changsha,China.I write to present a rare case report of 9p deletion syndrome with congenital infantile glaucoma in an infant,accompanying with an effective method of both diagnosis and treatment.
文摘目的建立一种基于两对交叉引物PCR技术(PCR with confronting two-pair primers,PCR-CTPP)同时快速检测非缺失型α地中海贫血WS、QS和CS三种突变类型的方法及其在临床中的应用。方法根据α珠蛋白基因中发生WS、QS和CS突变的区域基因序列,分别针对单个位点设计两对引物即通用外引物和特异性引物,经过聚合酶链反应、电泳鉴别基因型,同时检测非缺失型α地中海贫血。将该方法与PCR反向斑点杂交(PCR-RDB)技术比较,验证其检测准确性。结果PCR-CTPP方法可用于准确检测非缺失型α地中海贫血的WS、QS和CS突变类型,结果显示与常规非缺失型α地中海贫血PCR-RDB检测方法一致。结论PCR-CTPP技术检测非缺失型α地中海贫血WS、QS、CS三种突变位点,简单快速、经济省力,可用于非缺失型α地中海贫血的快速筛查和分子流行病学研究,适合在一般实验室推广应用。适用于非缺失型α地中海贫血的人群筛查及婚前或产前筛查,适合各个层次医院应用。
