Insulin was chemically modified with dehydrocholic acid without the use of protecting agents and the main monoacylated insulin. ε-NB29-Dehydrocholyl insulin was obtained selectively and analyzed by PAGE, HPLC and MAL...Insulin was chemically modified with dehydrocholic acid without the use of protecting agents and the main monoacylated insulin. ε-NB29-Dehydrocholyl insulin was obtained selectively and analyzed by PAGE, HPLC and MALDI-TOF-MS.展开更多
基金supported by the National Natural Science Foundation of China(Project No.20371018)the Research Fund from the Department of Education of Hubei Province
文摘Insulin was chemically modified with dehydrocholic acid without the use of protecting agents and the main monoacylated insulin. ε-NB29-Dehydrocholyl insulin was obtained selectively and analyzed by PAGE, HPLC and MALDI-TOF-MS.
