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腹腔镜下保留神经手术联合GnRH-a治疗深部浸润型子宫内膜异位症的疗效分析 被引量:10
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作者 魏刚 史欣 +1 位作者 王恒 韦君丽 《广西医科大学学报》 CAS 2018年第11期1543-1547,共5页
目的:探讨腹腔镜下保留神经手术联合促性腺释放激素激动剂(GnRH-a)治疗深部浸润型子宫内膜异位症(DIE)的临床疗效及机制。方法:将88例DIE患者随机分为观察组与对照组,每组44例。两组均行腹腔镜下保留神经手术治疗,观察组术后应用GnRH-a... 目的:探讨腹腔镜下保留神经手术联合促性腺释放激素激动剂(GnRH-a)治疗深部浸润型子宫内膜异位症(DIE)的临床疗效及机制。方法:将88例DIE患者随机分为观察组与对照组,每组44例。两组均行腹腔镜下保留神经手术治疗,观察组术后应用GnRH-a,对照组术后应用孕三烯酮。比较两组临床疗效、并发症、复发率及血清糖类抗原199(CA199)、基质金属蛋白酶-9 (MMP-9)、基质金属蛋白酶抑制剂-1(TIMP-1)和Th1/Th2细胞因子水平。结果 :术后6个月,观察组血清CA199、MMP-9、MMP-9/TIMP-1、白介素(IL)-4、IL-6、IL-10均显著低于对照组,TIMP-1、γ干扰素(IFN-γ)、IL-2均明显高于对照组(均P<0.05)。术后3个月、6个月、12个月,观察组疼痛视觉模拟量表(VAS)评分显著低于对照组(P<0.05)。两组治疗总有效率比较,差异无统计学意义(97.62%vs 90.24%,P>0.05),但观察组治愈率显著高于对照组(78.57%vs.53.66%,P<0.05)。观察组复发率显著低于对照组(4.88%vs.21.62%,P<0.05),妊娠率显著高于对照组(44.44%vs.20.00%,P<0.05)。结论:腹腔镜下保留神经手术联合GnRH-a治疗DIE安全、有效,能够降低复发率,其机制可能与调节Th1/Th2细胞平衡和MMP-9/TIMP-1平衡有关。 展开更多
关键词 深部浸润型子宫内膜异位症 腹腔镜 保留神经手术 GNRH-A
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Effects of straw size in buried straw layers on water movement in adjacent soil layers 被引量:9
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作者 Yao Mingze Li Bo +1 位作者 Wang Tieliang Feng Xue 《International Journal of Agricultural and Biological Engineering》 SCIE EI CAS 2016年第2期74-84,共11页
Deeply buried straw retention can improve the soil content of organic matter,its capacity for moisture preservation,the agroecological environment utilization efficiency of water resources,ensuring a stable crop yield... Deeply buried straw retention can improve the soil content of organic matter,its capacity for moisture preservation,the agroecological environment utilization efficiency of water resources,ensuring a stable crop yield;at the same time,the quantitative effects of deeply buried straw retention on soil moisture have a direct influence on the promotion and application of the technology.Using an infiltration and evaporation experiment of a one-dimensional soil column,the effects of straw size on the water content of the straw and the adjacent soil were evaluated when the straw was deeply buried in soil;the infiltration and evaporation features of different sized straw and its adjacent soil were analyzed;the hydraulic conductivity,sorptivity and saturated water content of the straw were obtained;in the end,the water distribution laws of straw and adjacent soil under the same conditions were concluded.The experiment was comprised of rod-shaped straw(RS),segment-shaped straw(SS)and filament-shaped straw(FS)to control treatment(CK).The results indicated that from the perspective of infiltration,the infiltration rate of filament-shape straw was the lowest at the stage of straw unsaturation.The hydraulic conductivities of rod-shaped,filament-shaped and segment-shaped straws are 4.01 mm/min,1.33 mm/min and 0.03 mm/min at the stage of straw and adjacent soil saturation,respectively.There is a strong effect on preventing infiltration from segment-shaped straw;with the help of the Philip model of long duration,the sorptivity of the soil with rod-shaped,filament-shaped and segment-shaped straws was 12.31 mm/min0.5,11.02 mm/min0.5 and 24.26 mm/min0.5 at the unsaturation stage,respectively.The segment-shape straw improved the water absorption capacity of the soil and straw column.The water retention capacities indicated that the saturated water contents of sandy loam,filament-shaped straw,segment-shaped straw and rod-shaped straw were 0.38 cm^(3)/cm^(3),0.29 cm^(3)/cm^(3),0.26 cm^(3)/cm^(3)and 0.13 cm^(3)/cm^(3),respectively.Addit 展开更多
关键词 deeply buried straw straw size soil moisture infiltration evaporation water retention
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深部浸润性子宫内膜异位症的研究进展 被引量:1
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作者 王素敏 唐卉 +1 位作者 史颖莉 张伟毅 《中国优生与遗传杂志》 2006年第7期125-127,共3页
子宫内膜异位症(内异症)有多种病理类型,不同类型具有不同的发病机制。深部浸润性内异症是指异位灶浸润深度超过5mm,其严重程度与盆腔疼痛及深部性交痛密切相关,因而得到越来越多的重视。本文综述近年来有关深部浸润性内异症研究进展的... 子宫内膜异位症(内异症)有多种病理类型,不同类型具有不同的发病机制。深部浸润性内异症是指异位灶浸润深度超过5mm,其严重程度与盆腔疼痛及深部性交痛密切相关,因而得到越来越多的重视。本文综述近年来有关深部浸润性内异症研究进展的相关文献。 展开更多
关键词 子宫内膜异位症 深部浸润 病机 诊断 治疗
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