Class III malocclusion associated with posterior crossbite, anterior open bite pattern with asymmetric occlusion in adults can be a challenging orthodontic problem, especially for the nonsurgical treatment. Skeletal C...Class III malocclusion associated with posterior crossbite, anterior open bite pattern with asymmetric occlusion in adults can be a challenging orthodontic problem, especially for the nonsurgical treatment. Skeletal Class III anteroposterior discrepancies in adult patients are generally managed either by surgical-orthodontic treatment or by orthodontic camouflage through dentoalveolar compensation. Although correction with surgery may be the most effective and stable way, many patients refuse surgical treatment plan because of the costs and traumas it may bring. This case report describes the successful use of TADs with expansion auxiliary wire to treat a 24-year-old man with skeletal class III malocclusion, posterior crossbite, anterior open-bite and asymmetric occlusion, mild upper and lower dental spacing and a chief manifestation of anterior crossbite. The patient refused surgery. A treatment plan was formulated consisting of using auxiliary expansion wire to expand the maxillary arch, 8 mm mini-screws between the roots of the mandibular canines and first premolars, preadjusted edgewise brackets to align the teeth, Class III and asymmetric elastics to correct the canines, premolars, and molars relationship and midline deviation, reverse curve of the nickel-titanium wire combined with anterior vertical elastics to intrude molars and correct the anterior open-bite. In this case, without going through surgery, the posterior cross-bite was corrected, and ideal overjet and overbite relationships, midline coincidence and functional occlusion were all achieved. Satisfactory occlusal, functional, esthetic and stable results were obtained.展开更多
背景:颞下颌关节骨关节炎是一种发病率很高的口腔常见病,而颞下颌关节骨关节炎早期隐匿不易被发现,临床上病理标本获取难度较高,难以开展相关研究。将数字化3D打印技术应用到颞下颌关节骨关节炎动物模型上来增加动物模型的一致性,从而...背景:颞下颌关节骨关节炎是一种发病率很高的口腔常见病,而颞下颌关节骨关节炎早期隐匿不易被发现,临床上病理标本获取难度较高,难以开展相关研究。将数字化3D打印技术应用到颞下颌关节骨关节炎动物模型上来增加动物模型的一致性,从而促进颞下颌关节骨关节炎疾病的研究。目的:利用新型数字技术建立标准化的颞下颌关节骨关节炎大鼠模型。方法:将30只SD雌性大鼠根据单侧前牙反牙合建模方法的不同,随机分为3组,传统模型组、数字化模型组和对照组,每组10只。于建模后4,8周采集髁突软骨标本,体式显微镜观察表观形态,苏木精-伊红染色、番红O/固绿染色观察病理形态,ELISA观察白细胞介素1β、肿瘤坏死因子α的表达变化,免疫组织化学染色观察蛋白多糖、Ⅱ型胶原及基质金属蛋白酶13的表达变化。结果与结论:(1)数字化模型组和传统模型组观察到不同程度的退行性病变。干预后第1周,模型组大鼠体质量均呈下降趋势,随后呈增长趋势,且显著低于对照组。(2)体式显微镜观察结果显示,建模后4,8周,数字化模型组表面的变形及缺损程度明显高于传统模型组。(3)两个时间点,数字化模型组和传统模型组的国际骨关节炎研究学会(Osteoarthritis Research Society International,OARSI)评分均高于对照组,数字化模型组高于传统模型组(P<0.05)。(4)组织病理学观察显示,建模后4,8周,两个模型组的改良Mankin评分和OARSI评分均显著高于同龄对照组(P<0.05)。(5)免疫组织化学染色结果显示,建模后4,8周,与同龄对照组相比,蛋白多糖及Ⅱ型胶原在传统模型组与数字化模型组两个时间点表达降低,基质金属蛋白酶13表达增强(P<0.05)。(6)ELISA结果显示,传统和数字化模型组大鼠8周时炎性因子白细胞介素1β和肿瘤坏死因子α的表达水平均高于同龄对照组,数字化模型组高于传统模型组(P<0.05)。(7)展开更多
文摘Class III malocclusion associated with posterior crossbite, anterior open bite pattern with asymmetric occlusion in adults can be a challenging orthodontic problem, especially for the nonsurgical treatment. Skeletal Class III anteroposterior discrepancies in adult patients are generally managed either by surgical-orthodontic treatment or by orthodontic camouflage through dentoalveolar compensation. Although correction with surgery may be the most effective and stable way, many patients refuse surgical treatment plan because of the costs and traumas it may bring. This case report describes the successful use of TADs with expansion auxiliary wire to treat a 24-year-old man with skeletal class III malocclusion, posterior crossbite, anterior open-bite and asymmetric occlusion, mild upper and lower dental spacing and a chief manifestation of anterior crossbite. The patient refused surgery. A treatment plan was formulated consisting of using auxiliary expansion wire to expand the maxillary arch, 8 mm mini-screws between the roots of the mandibular canines and first premolars, preadjusted edgewise brackets to align the teeth, Class III and asymmetric elastics to correct the canines, premolars, and molars relationship and midline deviation, reverse curve of the nickel-titanium wire combined with anterior vertical elastics to intrude molars and correct the anterior open-bite. In this case, without going through surgery, the posterior cross-bite was corrected, and ideal overjet and overbite relationships, midline coincidence and functional occlusion were all achieved. Satisfactory occlusal, functional, esthetic and stable results were obtained.
文摘背景:颞下颌关节骨关节炎是一种发病率很高的口腔常见病,而颞下颌关节骨关节炎早期隐匿不易被发现,临床上病理标本获取难度较高,难以开展相关研究。将数字化3D打印技术应用到颞下颌关节骨关节炎动物模型上来增加动物模型的一致性,从而促进颞下颌关节骨关节炎疾病的研究。目的:利用新型数字技术建立标准化的颞下颌关节骨关节炎大鼠模型。方法:将30只SD雌性大鼠根据单侧前牙反牙合建模方法的不同,随机分为3组,传统模型组、数字化模型组和对照组,每组10只。于建模后4,8周采集髁突软骨标本,体式显微镜观察表观形态,苏木精-伊红染色、番红O/固绿染色观察病理形态,ELISA观察白细胞介素1β、肿瘤坏死因子α的表达变化,免疫组织化学染色观察蛋白多糖、Ⅱ型胶原及基质金属蛋白酶13的表达变化。结果与结论:(1)数字化模型组和传统模型组观察到不同程度的退行性病变。干预后第1周,模型组大鼠体质量均呈下降趋势,随后呈增长趋势,且显著低于对照组。(2)体式显微镜观察结果显示,建模后4,8周,数字化模型组表面的变形及缺损程度明显高于传统模型组。(3)两个时间点,数字化模型组和传统模型组的国际骨关节炎研究学会(Osteoarthritis Research Society International,OARSI)评分均高于对照组,数字化模型组高于传统模型组(P<0.05)。(4)组织病理学观察显示,建模后4,8周,两个模型组的改良Mankin评分和OARSI评分均显著高于同龄对照组(P<0.05)。(5)免疫组织化学染色结果显示,建模后4,8周,与同龄对照组相比,蛋白多糖及Ⅱ型胶原在传统模型组与数字化模型组两个时间点表达降低,基质金属蛋白酶13表达增强(P<0.05)。(6)ELISA结果显示,传统和数字化模型组大鼠8周时炎性因子白细胞介素1β和肿瘤坏死因子α的表达水平均高于同龄对照组,数字化模型组高于传统模型组(P<0.05)。(7)
