Regenerative medicine and anti-aging research have made great strides at the molecular and cellular levels in dermatology and the medical aesthetic field,targeting potential treatments with skin therapeutic and interv...Regenerative medicine and anti-aging research have made great strides at the molecular and cellular levels in dermatology and the medical aesthetic field,targeting potential treatments with skin therapeutic and intervention pathways,which make it possible to develop effective skin regeneration and repair ingredients.With the rapid development of computational biology,bioinformatics as well as artificial intelligence(A.I.),the development of new ingredients for regenerative medicine has been greatly accelerated,and the success rate has been improved.Some application cases have appeared in topical skin regeneration and repair scenarios.This review will briefly introduce the application of bioactive peptides in skin repair and anti-aging as emerging ingredients in cosmeceutics and emphasize how A.I.based computational biology technology may accelerate the development of innovative peptide molecules and ultimately translate them into potential skin regenerative and anti-aging scenarios.Typically,two research routines have been summarized and current limitations as well as directions were discussed for border applications in future research.展开更多
Introduction: Cosmeceutical is a term used to describe cosmetics with antiaging effects these days. The aim of the current study was to determine the efficacy of different type of antiaging dermatological products bas...Introduction: Cosmeceutical is a term used to describe cosmetics with antiaging effects these days. The aim of the current study was to determine the efficacy of different type of antiaging dermatological products based on consumer self-assessment and to identify those driving factors that influence women’s purchase of these products and to have an insight into their perception and knowledge about these products. Methods: A prospective study was conducted about the use of antiaging cosmetics, consumer satisfaction, skin concerns related with age, importance of younger looking skin and socioeconomic status. Results and Discussion: It was observed in the study that such products do work to improve skin conditions but the claim that wrinkles could be cured completely could not be determined. Participant reported discrepancies between ideal and real effect of antiaging cosmetics. Even if such cosmetic products are expensive people like to spend on these to fulfill the human dream of looking younger.展开更多
The Baumann Skin Typing System diagnoses patients as having one of 16 skin types based on their answers to a validated questionnaire [i] known as the Baumann Skin Type Indicator [ii]. The BSTI questionnaire has been t...The Baumann Skin Typing System diagnoses patients as having one of 16 skin types based on their answers to a validated questionnaire [i] known as the Baumann Skin Type Indicator [ii]. The BSTI questionnaire has been tested over the last decade on over 200,000 people of various ages and ethnicities in different geographic locations around the world. In this study, data were collected from 52,862 patients to compare skin type prevalence between those who presented to doctor’s offices and those who took the quiz without supervision online. The most common skin types varied only slightly between patients that took the quiz online and those that completed the questionnaire in their doctor’s office. This indicates that the prevalence of skin types seen in the doctor’s office is similar to that in the general population and that supervision is not necessary to get an accurate result on the BSTI. [iii] In addition, comparison of data gathered in China, Korea, and the US did not show a significant difference in skin type prevalence between Asian and Caucasian skin types. [iv] This study demonstrates that the English version of the BSTI is valid for English speaking patients online, and in doctors’ offices in the US, China and Korea.展开更多
A flow-based iodometric extraction method for the determination of selenium sulfide was developed and applied to cosmeceutical products. Iodine which was generated from the reduction of selenium(IV) ions by iodide i...A flow-based iodometric extraction method for the determination of selenium sulfide was developed and applied to cosmeceutical products. Iodine which was generated from the reduction of selenium(IV) ions by iodide ion was on-line extracted using a polypropylene HFM (hollow fiber membrane) liquid extraction technique. The HFM extraction unit was constructed and used to support an organic solvent (hexane) and separate between the organic phase and aqueous phase. The resulting purple extract was carried to a fiber optic spectrophotometric detector for the measurement at 521 nm. Parameters which affected the extraction efficiency, sensitivity and sample throughput such as iodide (selenium molar ratio, extraction time and washing time between the cycles) were investigated and optimized. A linear dynamic range of 80-373 mg.Lt selenium solution was obtained with an extraction time of 60 sec. The total analysis time including washing was about 180 sec which provided a sample throughput of approximately 20 samples'hr1 and excluded the sample pre-treatment. The recoveries for the determination of selenium in the forms of selenium dioxide and selenium sulfide were in the range of 103%-104% with 1%-3% RSD (relative standard deviation). The relative errors of this method which was applied for determination of selenium sulfide levels in an anti-dandruff shampoo and a cosmeceutical bead sample were both less than 2.5%.展开更多
Background:The utilization of seaweed-based biologically active components in cosmeceutical formulations has been extensively rising due to skin health-promoting effects.Seaweeds have varieties of biologically active ...Background:The utilization of seaweed-based biologically active components in cosmeceutical formulations has been extensively rising due to skin health-promoting effects.Seaweeds have varieties of biologically active components and possess potential benefits in skincare products.Methods:Hence,the present study was done to characterize the bioactive constituents of green seaweed Chaetomorpha aerea by using the gas chromatography coupled with high-resolution mass spectrometry technique in ethanolic and methanolic extracts for presenting its cosmetic potential.Results:In analysis,a total of twenty-one different components were found in both the extracts.Their cosmetic potentials have been studied based on previous research studies.In addition,we characterized 9-octadecenoic acid[Z]-,phenylmethyl ester which belongs to benzyloxycarbonyls class.This compound exhibits promising applications in the cosmeceutical sector.This compound has a target peak percentage area(16.64%)with a retention time(39.1 min)in methanolic extract.Conclusion:The incorporation of seaweed-based bioactive components in cosmetics has been extensively growing due to its skin health-promoting effects.展开更多
基金supported by the Guangdong Basic and Applied Basic Research Foundation(No.2023A1515030047)Zhejiang Provincial Department of Agriculture and Rural Affairs(2022SNJF078).
文摘Regenerative medicine and anti-aging research have made great strides at the molecular and cellular levels in dermatology and the medical aesthetic field,targeting potential treatments with skin therapeutic and intervention pathways,which make it possible to develop effective skin regeneration and repair ingredients.With the rapid development of computational biology,bioinformatics as well as artificial intelligence(A.I.),the development of new ingredients for regenerative medicine has been greatly accelerated,and the success rate has been improved.Some application cases have appeared in topical skin regeneration and repair scenarios.This review will briefly introduce the application of bioactive peptides in skin repair and anti-aging as emerging ingredients in cosmeceutics and emphasize how A.I.based computational biology technology may accelerate the development of innovative peptide molecules and ultimately translate them into potential skin regenerative and anti-aging scenarios.Typically,two research routines have been summarized and current limitations as well as directions were discussed for border applications in future research.
文摘Introduction: Cosmeceutical is a term used to describe cosmetics with antiaging effects these days. The aim of the current study was to determine the efficacy of different type of antiaging dermatological products based on consumer self-assessment and to identify those driving factors that influence women’s purchase of these products and to have an insight into their perception and knowledge about these products. Methods: A prospective study was conducted about the use of antiaging cosmetics, consumer satisfaction, skin concerns related with age, importance of younger looking skin and socioeconomic status. Results and Discussion: It was observed in the study that such products do work to improve skin conditions but the claim that wrinkles could be cured completely could not be determined. Participant reported discrepancies between ideal and real effect of antiaging cosmetics. Even if such cosmetic products are expensive people like to spend on these to fulfill the human dream of looking younger.
文摘The Baumann Skin Typing System diagnoses patients as having one of 16 skin types based on their answers to a validated questionnaire [i] known as the Baumann Skin Type Indicator [ii]. The BSTI questionnaire has been tested over the last decade on over 200,000 people of various ages and ethnicities in different geographic locations around the world. In this study, data were collected from 52,862 patients to compare skin type prevalence between those who presented to doctor’s offices and those who took the quiz without supervision online. The most common skin types varied only slightly between patients that took the quiz online and those that completed the questionnaire in their doctor’s office. This indicates that the prevalence of skin types seen in the doctor’s office is similar to that in the general population and that supervision is not necessary to get an accurate result on the BSTI. [iii] In addition, comparison of data gathered in China, Korea, and the US did not show a significant difference in skin type prevalence between Asian and Caucasian skin types. [iv] This study demonstrates that the English version of the BSTI is valid for English speaking patients online, and in doctors’ offices in the US, China and Korea.
文摘A flow-based iodometric extraction method for the determination of selenium sulfide was developed and applied to cosmeceutical products. Iodine which was generated from the reduction of selenium(IV) ions by iodide ion was on-line extracted using a polypropylene HFM (hollow fiber membrane) liquid extraction technique. The HFM extraction unit was constructed and used to support an organic solvent (hexane) and separate between the organic phase and aqueous phase. The resulting purple extract was carried to a fiber optic spectrophotometric detector for the measurement at 521 nm. Parameters which affected the extraction efficiency, sensitivity and sample throughput such as iodide (selenium molar ratio, extraction time and washing time between the cycles) were investigated and optimized. A linear dynamic range of 80-373 mg.Lt selenium solution was obtained with an extraction time of 60 sec. The total analysis time including washing was about 180 sec which provided a sample throughput of approximately 20 samples'hr1 and excluded the sample pre-treatment. The recoveries for the determination of selenium in the forms of selenium dioxide and selenium sulfide were in the range of 103%-104% with 1%-3% RSD (relative standard deviation). The relative errors of this method which was applied for determination of selenium sulfide levels in an anti-dandruff shampoo and a cosmeceutical bead sample were both less than 2.5%.
基金financed by national funds through FCT-Foundation for Science and Technology,I.P.,within the scope of the projects UIDB/04292/2020 of MARE-Marine and Environmental Sciences Centre.
文摘Background:The utilization of seaweed-based biologically active components in cosmeceutical formulations has been extensively rising due to skin health-promoting effects.Seaweeds have varieties of biologically active components and possess potential benefits in skincare products.Methods:Hence,the present study was done to characterize the bioactive constituents of green seaweed Chaetomorpha aerea by using the gas chromatography coupled with high-resolution mass spectrometry technique in ethanolic and methanolic extracts for presenting its cosmetic potential.Results:In analysis,a total of twenty-one different components were found in both the extracts.Their cosmetic potentials have been studied based on previous research studies.In addition,we characterized 9-octadecenoic acid[Z]-,phenylmethyl ester which belongs to benzyloxycarbonyls class.This compound exhibits promising applications in the cosmeceutical sector.This compound has a target peak percentage area(16.64%)with a retention time(39.1 min)in methanolic extract.Conclusion:The incorporation of seaweed-based bioactive components in cosmetics has been extensively growing due to its skin health-promoting effects.