OBJECTIVE: To evaluate the effectiveness and safety of filiform needle acupuncture for poststroke depression, and to compare acupuncture with the therapeutic efficacy of antidepressant drugs. DATA RETRIEVAL: We retr...OBJECTIVE: To evaluate the effectiveness and safety of filiform needle acupuncture for poststroke depression, and to compare acupuncture with the therapeutic efficacy of antidepressant drugs. DATA RETRIEVAL: We retrieved data from the Chinese National Knowledge Infrastructure (1979-2012), Wanfang (1980-2012), VIP (1989-2012), Chinese Biomedical Literature (1975- 2012), PubMed (1966-2012), Ovid Lww (-2012), and Cochrane Library (-2012) Database using the internet. SELECTION CRITERIA: Randomized controlled trials on filiform needle acupuncture versus antidepressant drugs for treatment of poststroke depression were included. Moreover, the in- cluded articles scored at least 4 points on the Jadad scale. Exclusion criteria: other acupuncture therapies as treatment group, not stroke-induced depression patients, score 〈 4 points, non-ran- domized controlled trials, or animal trials. MAIN OUTCOME MEASURES: These were the Hamilton Depression Scale scores, clinical ef- fective rate, Self-Rating Depression Scale scores, Side Effect Rating Scale scores, and incidence of adverse reaction and events. RESULTS: A total of 17 randomized controlled clinical trials were included. Meta-analysis results displayed that after 4 weeks of treatment, clinical effective rate was better in patients treated with fill- form needle acupuncture than those treated with simple antidepressant drugs [relative risk = 1.11, 95% confidence interval (C/): 1.03-1.21, P = 0.01]. At 6 weeks, clinical effective rate was similar between filiform needle acupuncture and antidepressant drug groups. At 2 weeks after filiform needle acupuncture, Hamilton Depression Scale (17 items) scores were lower than in the antide- pressant drug group (mean difference = -2.34, 95%CI: -3.46 to -1.22, P 〈 0.000,1). At 4 weeks, Hamilton Depression Scale (24 items) scores were similar between filiform needle acupuncture and antidepressant drug groups. Self-Rating Depression Scale scores were lower in filiform needle展开更多
Software cybernetics explores the interplay between control theory/engineering and software theory/engineering. The controlled Markov chains (CMC) approach to software testing follows the idea of software cybernetics ...Software cybernetics explores the interplay between control theory/engineering and software theory/engineering. The controlled Markov chains (CMC) approach to software testing follows the idea of software cybernetics and treats software testing as a control problem. The software under test serves as a controlled object and the software testing strategy serves as the corresponding controller. The software under test and the software testing strategy make up a closed-loop feedback control system, and the theory of controlled Markov chains can be used to design and optimize software testing strategies in accordance with testing/reliability goals given a priori. In this paper we apply the CMC approach to the optimal stopping problem of multi-project software testing. The problem under consideration assumes that a single stopping action can stop testing of all the software systems under test simultaneously. The theoretical results presented in this paper describe how to test multiple software systems and when to stop testing in an optimal manner. An illustrative example is used to explain the theoretical results. The study of this paper further justifies the effectiveness of the CMC approach to software testing in particular and the idea of software cybernetics in general.展开更多
基金supported by the Guangdong Provincial"211 Engineering"Stage-III Key Disciplines Construction Project in China,No.Yue 2009431
文摘OBJECTIVE: To evaluate the effectiveness and safety of filiform needle acupuncture for poststroke depression, and to compare acupuncture with the therapeutic efficacy of antidepressant drugs. DATA RETRIEVAL: We retrieved data from the Chinese National Knowledge Infrastructure (1979-2012), Wanfang (1980-2012), VIP (1989-2012), Chinese Biomedical Literature (1975- 2012), PubMed (1966-2012), Ovid Lww (-2012), and Cochrane Library (-2012) Database using the internet. SELECTION CRITERIA: Randomized controlled trials on filiform needle acupuncture versus antidepressant drugs for treatment of poststroke depression were included. Moreover, the in- cluded articles scored at least 4 points on the Jadad scale. Exclusion criteria: other acupuncture therapies as treatment group, not stroke-induced depression patients, score 〈 4 points, non-ran- domized controlled trials, or animal trials. MAIN OUTCOME MEASURES: These were the Hamilton Depression Scale scores, clinical ef- fective rate, Self-Rating Depression Scale scores, Side Effect Rating Scale scores, and incidence of adverse reaction and events. RESULTS: A total of 17 randomized controlled clinical trials were included. Meta-analysis results displayed that after 4 weeks of treatment, clinical effective rate was better in patients treated with fill- form needle acupuncture than those treated with simple antidepressant drugs [relative risk = 1.11, 95% confidence interval (C/): 1.03-1.21, P = 0.01]. At 6 weeks, clinical effective rate was similar between filiform needle acupuncture and antidepressant drug groups. At 2 weeks after filiform needle acupuncture, Hamilton Depression Scale (17 items) scores were lower than in the antide- pressant drug group (mean difference = -2.34, 95%CI: -3.46 to -1.22, P 〈 0.000,1). At 4 weeks, Hamilton Depression Scale (24 items) scores were similar between filiform needle acupuncture and antidepressant drug groups. Self-Rating Depression Scale scores were lower in filiform needle
基金supported by the National Outstanding Youth Foundation of China,the"863"Programme of China and the Aviation Science Foundation of China.
文摘Software cybernetics explores the interplay between control theory/engineering and software theory/engineering. The controlled Markov chains (CMC) approach to software testing follows the idea of software cybernetics and treats software testing as a control problem. The software under test serves as a controlled object and the software testing strategy serves as the corresponding controller. The software under test and the software testing strategy make up a closed-loop feedback control system, and the theory of controlled Markov chains can be used to design and optimize software testing strategies in accordance with testing/reliability goals given a priori. In this paper we apply the CMC approach to the optimal stopping problem of multi-project software testing. The problem under consideration assumes that a single stopping action can stop testing of all the software systems under test simultaneously. The theoretical results presented in this paper describe how to test multiple software systems and when to stop testing in an optimal manner. An illustrative example is used to explain the theoretical results. The study of this paper further justifies the effectiveness of the CMC approach to software testing in particular and the idea of software cybernetics in general.