Background Compensatory sweating （CS） is one of the most common postoperative complications after thoracic sympathectomy, sympathicotomy or endoscopic sympathetic block （ESB） for palmar hyperhidrosis. This study w...Background Compensatory sweating （CS） is one of the most common postoperative complications after thoracic sympathectomy, sympathicotomy or endoscopic sympathetic block （ESB） for palmar hyperhidrosis. This study was conducted to examine the relevance between CS and the sympathetic segment being transected in the surgical treatment of palmar hyperhidrosis, and thus to detect the potential mechanism of the occurrence of CS. Methods Between October 2004 and June 2006, 163 patients with primary hyperhidrosis were randomly divided into two groups, T3 sympathicotomy （78 patients） and T4 sympathicotomy（85）, who were operated upon under general anesthesia via single lumen intubation and intercostal video-mediastinoscopy （VM）. Results No morbidity or mortality occurred. Palmar hyperhidrosis was cured in all patients. Follow-up（mean （13.8i-6.2） months） showed no recurrence of palmar hyperhidrosis. The difference of rates of mild CS in groups T3 and T4 was of no statistical significance. The rate of moderate CS was significantly lower in group T4 than in group T3. No severe CS occurred. Conclusion The rates of occurrence and severity of CS are lowered with the lower sympathetic chain being transected.展开更多
With improvements in personnel and vehicular body armor,robust casualty evacuation capabilities,and damage control resuscitation strategies,more combat casualties are surviving to reach higher levels of care throughou...With improvements in personnel and vehicular body armor,robust casualty evacuation capabilities,and damage control resuscitation strategies,more combat casualties are surviving to reach higher levels of care throughout the casualty evacuation system.As such,medical centers are becoming more accustomed to managing the deleterious late consequences of combat trauma related to the dysregulation of the immune system.In this review,we aim to highlight these late consequences and identify areas for future research and therapeutic strategies.Trauma leads to the dysregulation of both the innate and adaptive immune responses,which places the injured at risk for several late consequences,including delayed wound healing,late onset sepsis and infection,multi-organ dysfunction syndrome,and acute respiratory distress syndrome,which are significant for their association with the increased morbidity and mortality of wounded personnel.The mechanisms by which these consequences develop are complex but include an imbalance of the immune system leading to robust inflammatory responses,triggered by the presence of damage associated molecules and other immune-modifying agents following trauma.Treatment strategies to improve outcomes have been difficult to develop as the immunophenotype of injured personnel following trauma is variable,fluid and difficult to determine.As more information regarding the triggers that lead to immune dysfunction following trauma is elucidated,it may be possible to identify the immunophenotype of injured personnel and provide targeted treatments to reduce the late consequences of trauma,which are known to lead to significant morbidity and mortality.展开更多
Background Video-assisted thoracic sympathetic block is an effective, safe, and minimally invasive method for treatment of primary hyperhidrosis. The purpose of this study was to decide which one of using electrocaute...Background Video-assisted thoracic sympathetic block is an effective, safe, and minimally invasive method for treatment of primary hyperhidrosis. The purpose of this study was to decide which one of using electrocautery hook and titanium clip is the appropriate procedure for primary palmar hyperhidrosis by assessing the compensatory sweating （CS） and quality of life （QOL） of patients after sympathetic block. Methods Between October 2007 to August 2010, 120 patients with primary palmar hyperhidrosis were randomly divided into two groups, electrocautery hook group （60 patients） and titanium clip group （60 patients）. All patients were treated by sympathetic block at T4 level. The CS was graded based on severity and location; the QOL was classified to 5 different levels based upon the summed total scores （range from 20 to 100） before and after surgery. The variables were compared. Results The postoperative follow-up period was 2 months. All patients were cured. Three patients in electrocautery hook group and 1 patient in titanium clip group had a unilateral pneumothorax on chest X-ray, but none of them was necessary to have chest drainage. Neither perioperative mortality nor serious complications such as cardiac arrhythmia or arrest were observed during the operation. No bradycardia or Horner＇s syndrome occured. CS was not more common in patients in titanium clip group than in those in electrocautery hook group （P=0.001）. Moderate and severe CS was few in all patients, and there was no significant difference between two groups （P=0.193）. Most of the patients feel a notable improvement of the the QOL; nevertheless, there was no significant difference between the groups （P=0.588）. Conclusions Both electrocautery hook and titanium clip used for sympathetic block at the T4 level are effective, safe, and minimally invasive for palmar hyperhidrosis. Because of the lower severity of CS and the similar improvements in the QOL after operation, we prefer to use of titanium clip for treating pa展开更多
Plant community structure responds strongly to anthropogenic disturbances, which greatly influence community stability. The changes in community structure, aboveground biomass（AGB）, biodiversity and community stabil...Plant community structure responds strongly to anthropogenic disturbances, which greatly influence community stability. The changes in community structure, aboveground biomass（AGB）, biodiversity and community stability associated with different management practices were studied with a three-year field investigation in a temperate steppe of Inner Mongolia, China. The species richness, Shannon-Wiener index, evenness, plant functional type abundance, AGB, temporal community stability, summed covariance, scaling coefficient and dominant species stability were compared among areas subjected to long-term reservation（R）, long-term grazing（G）, mowing since enclosure in 2008（M） and grazing enclosure since 2008（E）. Site R had higher perennial grass abundance and lower species richness than sites G, M and E, although the AGB was not significantly different among the four sites. The species structure varied from a single dominant species at site R to multiple dominant species at sites G, M and E. The long-term reservation grassland had lower biodiversity but higher stability, whereas the enclosed grassland with/without mowing had higher biodiversity but lower stability. Different stability mechanisms, such as the compensatory dynamics, mean-variance scaling and dominant species stability were examined. Results showed that community stability was most closely related to the relative stability of the dominant species, which supports the biomass ratio hypothesis proposed by Grime.展开更多
This study explores the role of a traditional tillage method,i.e.,compensatory hoeing,for sustainable agro-ecosystem management in the hilly areas of the Chongqing municipality,south-western China.To validate the effe...This study explores the role of a traditional tillage method,i.e.,compensatory hoeing,for sustainable agro-ecosystem management in the hilly areas of the Chongqing municipality,south-western China.To validate the effects of compensatory tillage on the terraced slopes,the tillage method of noncompensatory hoeing was conducted on a linear slope.To acquire information about 137 Cs inventories and soil texture,soil samples were collected by a core sampler with a 6.8-cm diameter at 5.0-m intervals along the toposequence and the linear slope in the dry season(March) of 2007.Meanwhile,a tillage erosion model was used for evaluating the spatial pattern of tillage erosion.The 137 Cs data showed that on the terraced slope,soil was lost from the upper slope,and soil deposition occurred at the toe slope positions on each terrace.As a result,abrupt changes in the 137 Cs inventories of soil were found over short distances between two sides of terrace boundaries.Results obtained from the tillage erosion model and the 137 Cs data indicate that soil redistribution mainly results from tillage erosion in the terraced landscape.Consecutive non-compensatory tillage caused soil redistribution on the linear slope,resulting in thin soil profile disappearing at the top and soil accumulating at the bottom positions of the linear slope.This result further validates that compensatory tillage could avoid the complete erosion of the thin soil layer at the summit position.Therefore,this traditional tillage.method,i.e.,compensatory tillage,has maintained the soil quality at the summit of the slope in the past decades.展开更多
Background Subjective cognitive decline(SCD)is a preclinical stage along the Alzheimer’s disease(AD)continuum.However,little is known about the aberrant patterns of connectivity and topological alterations of the bra...Background Subjective cognitive decline(SCD)is a preclinical stage along the Alzheimer’s disease(AD)continuum.However,little is known about the aberrant patterns of connectivity and topological alterations of the brain functional connectome and their diagnostic value in SCD.Methods Resting-state functional magnetic resonance imaging and graph theory analyses were used to investigate the alterations of the functional connectome in 66 SCD individuals and 64 healthy controls(HC).Pearson correlation analysis was computed to assess the relationships among network metrics,neuropsychological performance and pathological biomarkers.Finally,we used the multiple kernel learning-support vector machine(MKL-SVM)to differentiate the SCD and HC individuals.Results SCD individuals showed higher nodal topological properties(including nodal strength,nodal global efficiency and nodal local efficiency)associated with amyloid-βlevels and memory function than the HC,and these regions were mainly located in the default mode network(DMN).Moreover,increased local and medium-range connectivity mainly between the bilateral parahippocampal gyrus(PHG)and other DMN-related regions was found in SCD individuals compared with HC individuals.These aberrant functional network measures exhibited good classification performance in the differentiation of SCD individuals from HC individuals at an accuracy up to 79.23%.Conclusion The findings of this study provide insight into the compensatory mechanism of the functional connectome underlying SCD.The proposed classification method highlights the potential of connectome-based metrics for the identification of the preclinical stage of AD.展开更多
The aircraft engine multi-loop control system is described and the switching control theory is introduced to solve the regulating and protecting control problems in this paper. The aircraft engine multi-loop control s...The aircraft engine multi-loop control system is described and the switching control theory is introduced to solve the regulating and protecting control problems in this paper. The aircraft engine multi-loop control system is firstly described and the control problems are formulated. Secondly, the theory of the smooth switching control is devoted and a new extended scheme for the smooth switching of a switched control system is introduced. Then, for the key technologies of aero-engines switching control, a design algorithm is presented which can determine which candidate controller should be put in feedback with the plant to achieve a desired performance and the procedure to design the aircraft engine multi-loop control system is detailed. The switching performance objectives and the switching scheme are given and a family of PID controllers and compensators is designed. The simulation shows that using the switching control design method can not only improve the dynamic performance of the aircraft engine control system and reduce the switching times, but also guarantee the stability in some peculiar occasions.展开更多
文摘Background Compensatory sweating （CS） is one of the most common postoperative complications after thoracic sympathectomy, sympathicotomy or endoscopic sympathetic block （ESB） for palmar hyperhidrosis. This study was conducted to examine the relevance between CS and the sympathetic segment being transected in the surgical treatment of palmar hyperhidrosis, and thus to detect the potential mechanism of the occurrence of CS. Methods Between October 2004 and June 2006, 163 patients with primary hyperhidrosis were randomly divided into two groups, T3 sympathicotomy （78 patients） and T4 sympathicotomy（85）, who were operated upon under general anesthesia via single lumen intubation and intercostal video-mediastinoscopy （VM）. Results No morbidity or mortality occurred. Palmar hyperhidrosis was cured in all patients. Follow-up（mean （13.8i-6.2） months） showed no recurrence of palmar hyperhidrosis. The difference of rates of mild CS in groups T3 and T4 was of no statistical significance. The rate of moderate CS was significantly lower in group T4 than in group T3. No severe CS occurred. Conclusion The rates of occurrence and severity of CS are lowered with the lower sympathetic chain being transected.
基金RJS was supported by National Institutes of Health grants,K08-GM117367.
文摘With improvements in personnel and vehicular body armor,robust casualty evacuation capabilities,and damage control resuscitation strategies,more combat casualties are surviving to reach higher levels of care throughout the casualty evacuation system.As such,medical centers are becoming more accustomed to managing the deleterious late consequences of combat trauma related to the dysregulation of the immune system.In this review,we aim to highlight these late consequences and identify areas for future research and therapeutic strategies.Trauma leads to the dysregulation of both the innate and adaptive immune responses,which places the injured at risk for several late consequences,including delayed wound healing,late onset sepsis and infection,multi-organ dysfunction syndrome,and acute respiratory distress syndrome,which are significant for their association with the increased morbidity and mortality of wounded personnel.The mechanisms by which these consequences develop are complex but include an imbalance of the immune system leading to robust inflammatory responses,triggered by the presence of damage associated molecules and other immune-modifying agents following trauma.Treatment strategies to improve outcomes have been difficult to develop as the immunophenotype of injured personnel following trauma is variable,fluid and difficult to determine.As more information regarding the triggers that lead to immune dysfunction following trauma is elucidated,it may be possible to identify the immunophenotype of injured personnel and provide targeted treatments to reduce the late consequences of trauma,which are known to lead to significant morbidity and mortality.
文摘Background Video-assisted thoracic sympathetic block is an effective, safe, and minimally invasive method for treatment of primary hyperhidrosis. The purpose of this study was to decide which one of using electrocautery hook and titanium clip is the appropriate procedure for primary palmar hyperhidrosis by assessing the compensatory sweating （CS） and quality of life （QOL） of patients after sympathetic block. Methods Between October 2007 to August 2010, 120 patients with primary palmar hyperhidrosis were randomly divided into two groups, electrocautery hook group （60 patients） and titanium clip group （60 patients）. All patients were treated by sympathetic block at T4 level. The CS was graded based on severity and location; the QOL was classified to 5 different levels based upon the summed total scores （range from 20 to 100） before and after surgery. The variables were compared. Results The postoperative follow-up period was 2 months. All patients were cured. Three patients in electrocautery hook group and 1 patient in titanium clip group had a unilateral pneumothorax on chest X-ray, but none of them was necessary to have chest drainage. Neither perioperative mortality nor serious complications such as cardiac arrhythmia or arrest were observed during the operation. No bradycardia or Horner＇s syndrome occured. CS was not more common in patients in titanium clip group than in those in electrocautery hook group （P=0.001）. Moderate and severe CS was few in all patients, and there was no significant difference between two groups （P=0.193）. Most of the patients feel a notable improvement of the the QOL; nevertheless, there was no significant difference between the groups （P=0.588）. Conclusions Both electrocautery hook and titanium clip used for sympathetic block at the T4 level are effective, safe, and minimally invasive for palmar hyperhidrosis. Because of the lower severity of CS and the similar improvements in the QOL after operation, we prefer to use of titanium clip for treating pa
基金funded by the National Natural Science Foundation of China (41030535, 41371069)the Fundamental Research Funds for the Central Universitiesthe Program for Changjiang Scholars and Innovative Research Team in University (IRT1108)
文摘Plant community structure responds strongly to anthropogenic disturbances, which greatly influence community stability. The changes in community structure, aboveground biomass（AGB）, biodiversity and community stability associated with different management practices were studied with a three-year field investigation in a temperate steppe of Inner Mongolia, China. The species richness, Shannon-Wiener index, evenness, plant functional type abundance, AGB, temporal community stability, summed covariance, scaling coefficient and dominant species stability were compared among areas subjected to long-term reservation（R）, long-term grazing（G）, mowing since enclosure in 2008（M） and grazing enclosure since 2008（E）. Site R had higher perennial grass abundance and lower species richness than sites G, M and E, although the AGB was not significantly different among the four sites. The species structure varied from a single dominant species at site R to multiple dominant species at sites G, M and E. The long-term reservation grassland had lower biodiversity but higher stability, whereas the enclosed grassland with/without mowing had higher biodiversity but lower stability. Different stability mechanisms, such as the compensatory dynamics, mean-variance scaling and dominant species stability were examined. Results showed that community stability was most closely related to the relative stability of the dominant species, which supports the biomass ratio hypothesis proposed by Grime.
基金provided by the Special Support Foundation of the Institute of Mountain Hazards and Environment (IMHE)the 100 Talents Programme of IMHE,Chinese Academy of Sciences (No. SDSQB-2011-01)
文摘This study explores the role of a traditional tillage method,i.e.,compensatory hoeing,for sustainable agro-ecosystem management in the hilly areas of the Chongqing municipality,south-western China.To validate the effects of compensatory tillage on the terraced slopes,the tillage method of noncompensatory hoeing was conducted on a linear slope.To acquire information about 137 Cs inventories and soil texture,soil samples were collected by a core sampler with a 6.8-cm diameter at 5.0-m intervals along the toposequence and the linear slope in the dry season(March) of 2007.Meanwhile,a tillage erosion model was used for evaluating the spatial pattern of tillage erosion.The 137 Cs data showed that on the terraced slope,soil was lost from the upper slope,and soil deposition occurred at the toe slope positions on each terrace.As a result,abrupt changes in the 137 Cs inventories of soil were found over short distances between two sides of terrace boundaries.Results obtained from the tillage erosion model and the 137 Cs data indicate that soil redistribution mainly results from tillage erosion in the terraced landscape.Consecutive non-compensatory tillage caused soil redistribution on the linear slope,resulting in thin soil profile disappearing at the top and soil accumulating at the bottom positions of the linear slope.This result further validates that compensatory tillage could avoid the complete erosion of the thin soil layer at the summit position.Therefore,this traditional tillage.method,i.e.,compensatory tillage,has maintained the soil quality at the summit of the slope in the past decades.
基金This work was supported partly by grants from the National Natural Science Foundation of China(No.81822013,81671665)Jiangsu Provincial Key Medical Talents(No.ZDRCA2016085)+2 种基金the Key Research and Development Program of Jiangsu Province of China(BE2016610)the National Key Research and Development Program of China(2016YFC1300500–504)Jiangsu Province Key Medical Discipline(ZDXKA2016020).
文摘Background Subjective cognitive decline(SCD)is a preclinical stage along the Alzheimer’s disease(AD)continuum.However,little is known about the aberrant patterns of connectivity and topological alterations of the brain functional connectome and their diagnostic value in SCD.Methods Resting-state functional magnetic resonance imaging and graph theory analyses were used to investigate the alterations of the functional connectome in 66 SCD individuals and 64 healthy controls(HC).Pearson correlation analysis was computed to assess the relationships among network metrics,neuropsychological performance and pathological biomarkers.Finally,we used the multiple kernel learning-support vector machine(MKL-SVM)to differentiate the SCD and HC individuals.Results SCD individuals showed higher nodal topological properties(including nodal strength,nodal global efficiency and nodal local efficiency)associated with amyloid-βlevels and memory function than the HC,and these regions were mainly located in the default mode network(DMN).Moreover,increased local and medium-range connectivity mainly between the bilateral parahippocampal gyrus(PHG)and other DMN-related regions was found in SCD individuals compared with HC individuals.These aberrant functional network measures exhibited good classification performance in the differentiation of SCD individuals from HC individuals at an accuracy up to 79.23%.Conclusion The findings of this study provide insight into the compensatory mechanism of the functional connectome underlying SCD.The proposed classification method highlights the potential of connectome-based metrics for the identification of the preclinical stage of AD.
基金supported by the National Natural Science Foundation of China (Grant No. 61104146/F030203)Innovation Plan of Aero Engine Complex System Safety by the Ministry of Education Chang Jiang Scholars of China (Grant No. IRT0905)
文摘The aircraft engine multi-loop control system is described and the switching control theory is introduced to solve the regulating and protecting control problems in this paper. The aircraft engine multi-loop control system is firstly described and the control problems are formulated. Secondly, the theory of the smooth switching control is devoted and a new extended scheme for the smooth switching of a switched control system is introduced. Then, for the key technologies of aero-engines switching control, a design algorithm is presented which can determine which candidate controller should be put in feedback with the plant to achieve a desired performance and the procedure to design the aircraft engine multi-loop control system is detailed. The switching performance objectives and the switching scheme are given and a family of PID controllers and compensators is designed. The simulation shows that using the switching control design method can not only improve the dynamic performance of the aircraft engine control system and reduce the switching times, but also guarantee the stability in some peculiar occasions.
